Statins Decrease Lung Inflammation in Mice by Upregulating Tetraspanin CD9 in Macrophages

Statins as a Novel Therapeutic Strategy in Acute Lung Injury

(2012) Sunit Singla et al.   Pulmonary Circulation

Lipid rafts: A signalling platform linking lipoprotein metabolism to atherogenesis

(2011) Stéphanie Lemaire-Ewing et al.   ATHEROSCLEROSIS

The complexity of tetraspanins: Figure 1

(2011) Eric Rubinstein   BIOCHEMICAL SOCIETY TRANSACTIONS

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Mechanisms for the anti-inflammatory effects of statins

(2011) De-xiu Bu et al.   CURRENT OPINION IN LIPIDOLOGY

Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients

(2011) Deepti Malhotra et al.   JOURNAL OF CLINICAL INVESTIGATION

Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 macrophages

(2011) Pak-On Leung et al.   TOXICOLOGY LETTERS

Statin Reverses Smoke-induced Pulmonary Hypertension and Prevents Emphysema but Not Airway Remodeling

(2010) Joanne L. Wright et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Randomized Clinical Trial of Hydroxymethylglutaryl– Coenzyme A Reductase Inhibition for Acute Lung Injury (The HARP Study)

(2010) Thelma R. Craig et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

(2010) Jason W. Rosch et al.   JOURNAL OF CLINICAL INVESTIGATION

Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers

(2009) Murali Shyamsundar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Systemic manifestations and comorbidities of COPD

(2009) P. J. Barnes et al.   EUROPEAN RESPIRATORY JOURNAL

Tetraspanin CD9 Negatively Regulates Lipopolysaccharide-Induced Macrophage Activation and Lung Inflammation

(2009) Mayumi Suzuki et al.   JOURNAL OF IMMUNOLOGY

Simvastatin attenuates experimental small airway remodelling in rats

(2009) Xue-Mei OU et al.   RESPIROLOGY

Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes

(2009) María Yáñez-Mó et al.   TRENDS IN CELL BIOLOGY

Associations between statins and COPD: a systematic review

(2009) Claudia C Dobler et al.   BMC Pulmonary Medicine

Role of HDAC2 in the Pathophysiology of COPD

(2008) Peter J. Barnes   Annual Review of Physiology

Complex chronic comorbidities of COPD

(2008) L. M. Fabbri et al.   EUROPEAN RESPIRATORY JOURNAL

Statins: under investigation for increasing bone mineral density and augmenting fracture healing

(2008) Quen Oak Tang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Double Deficiency of Tetraspanins CD9 and CD81 Alters Cell Motility and Protease Production of Macrophages and Causes Chronic Obstructive Pulmonary Disease-like Phenotype in Mice

(2008) Yoshito Takeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation

(2008) Kamala P. Sundararaj et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of macrophage adhesion and migration by Rho GTP-binding proteins

(2008) A.J. RIDLEY   JOURNAL OF MICROSCOPY