Specialized pro-resolving mediator network: an update on production and actions

Preface

(2020) Dipak Panigrahy et al.   CANCER AND METASTASIS REVIEWS

Resolvin D1 Administration is Beneficial in Trypanosoma cruzi Infection

(2020) Aline L. Horta et al.   INFECTION AND IMMUNITY

MCTR1 alleviates lipopolysaccharide‐induced acute lung injury by protecting lung endothelial glycocalyx

(2020) Hui Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA

(2020) D. Fussbroich et al.   Mucosal Immunology

Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization

(2020) Kai Shan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Maresin 1 Promotes Wound Healing and Socket Bone Regeneration for Alveolar Ridge Preservation

(2020) C.W. Wang et al.   JOURNAL OF DENTAL RESEARCH

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parenteral Fish‐Oil Emulsions in Critically Ill COVID‐19 Emulsions

(2020) Bruce R. Bistrian   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Letter to the Editor in relation to Bistrian BR. Parenteral fish oil emulsions in critically ill COVID‐19 emulsions [published online ahead of print, 2020 May 8]. JPEN J Parenter Enteral Nutr. 2020;10.1002/jpen.1871

(2020) Raquel S. Torrinhas et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Shifting the paradigm from inhibitors of inflammation to resolvers of inflammation in periodontitis

(2020) Thomas E. Van Dyke   JOURNAL OF PERIODONTOLOGY

A Novel Mechanism of Specialized Proresolving Lipid Mediators Mitigating Radicular Pain: The Negative Interaction with NLRP3 Inflammasome

(2020) Yi-hao Wang et al.   NEUROCHEMICAL RESEARCH

Balancing the Effect of Leukotrienes in Asthma

(2020) Catherine Godson   NEW ENGLAND JOURNAL OF MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Covid-19, Angiogenesis, and ARDS Endotypes

(2020) Lida Hariri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resolvin E1 is a pro-repair molecule that promotes intestinal epithelial wound healing

(2020) Miguel Quiros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

15-Epi-LXA4and 17-epi-RvD1 restore TLR9-mediated impaired neutrophil phagocytosis and accelerate resolution of lung inflammation

(2020) Meriem Sekheri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Synthesis of Benzene Congeners of Resolvin E2, a Proresolving Lipid Mediator, as Its Stable Equivalents

(2020) Yuto Murakami et al.   ACS Medicinal Chemistry Letters

N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease

(2020) Ju Youn Lee et al.   Nature Communications

Resolvin D1 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Increasing Treg Percentages via the ALX/FPR2 Pathway

(2020) Hong Luan et al.   Frontiers in Physiology

Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans

(2020) Sharon E Fox et al.   Lancet Respiratory Medicine

Resolvin D1 Reduces Lung Infection and Inflammation Activating Resolution in Cystic Fibrosis

(2020) Elisa Isopi et al.   Frontiers in Immunology

Race‐based and sex‐based differences in bioactive lipid mediators after myocardial infarction

(2020) Ganesh V. Halade et al.   ESC Heart Failure

Pro‐resolving mediator protectin D1 promotes epimorphic regeneration by controlling immune cell function in vertebrates

(2020) Mai Nguyen‐Chi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Omega-3 Polyunsaturated Fatty Acids Decrease Aortic Valve Disease through the Resolvin E1 and ChemR23 Axis

(2020) Gonzalo Artiach et al.   CIRCULATION

COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

(2020) Alexander V. Sorokin et al.   FASEB JOURNAL

Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity

(2020) Bochra Tourki et al.   FASEB JOURNAL

PCTR1 improves pulmonary edema fluid clearance through activating the sodium channel and lymphatic drainage in lipopolysaccharide‐induced ARDS

(2020) Pu‐hong Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neutrophils and COVID-19: Nots, NETs, and knots

(2020) Carl Nathan   JOURNAL OF EXPERIMENTAL MEDICINE

COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation

(2020) Duraisamy Kempuraj et al.   NEUROSCIENTIST

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

RvE1 uses the LTB4 receptor BLT1 to increase [Ca2+]i and stimulate mucin secretion in cultured rat and human conjunctival goblet cells

(2020) Menglu Yang et al.   Ocular Surface

Myeloid ALX/FPR2 regulates vascularization following tissue injury

(2020) Brian E. Sansbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential Immunotherapeutic Targets For Hypoxia Due to COVI-FLU

(2020) Yan Leyfman et al.   SHOCK

Use of Specialized Pro‐Resolving Mediators to Alleviate Cold Platelet Storage Lesion

(2020) Kristin M. Reddoch‐Cardenas et al.   TRANSFUSION

Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease

(2020) Melinda S. Schaller et al.   Journal of the American Heart Association

Omics-wide quantitative B-cell infiltration analyses identify GPR18 for human cancer prognosis with superiority over CD20

(2020) Yuchen Liu et al.   Communications Biology

Pro-resolving lipid mediator ameliorates obesity induced osteoarthritis by regulating synovial macrophage polarisation

(2019) Antonia Rujia Sun et al.   Scientific Reports

Treatment with maresin 1, a docosahexaenoic acid-derived pro-resolution lipid, protects skin from inflammation and oxidative stress caused by UVB irradiation

(2019) Talita L. C. Cezar et al.   Scientific Reports

Aspirin-triggered proresolving mediators stimulate resolution in cancer

(2019) Molly M. Gilligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

(2019) Yong-Hyun Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukocytes from obese individuals exhibit an impaired SPM signature

(2019) Cristina López-Vicario et al.   FASEB JOURNAL

Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome

(2019) Markus Werner et al.   FASEB JOURNAL

The specialised pro‐resolving lipid mediator maresin 1 reduces inflammatory pain with a long‐lasting analgesic effect

(2019) Victor Fattori et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells

(2019) Nora Botten et al.   FASEB JOURNAL

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration

(2019) Nikolas Giannakis et al.   NATURE IMMUNOLOGY

Resolvin D4 attenuates the severity of pathological thrombosis in mice

(2019) Deya Cherpokova et al.   BLOOD

Herring roe oil supplementation alters microglial cell gene expression and reduces peripheral inflammation after immune activation in a neonatal piglet model

(2019) Megan P. Caputo et al.   BRAIN BEHAVIOR AND IMMUNITY

Resolvin D1 promotes the targeting and clearance of necroptotic cells

(2019) Brennan D. Gerlach et al.   CELL DEATH AND DIFFERENTIATION

Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases

(2019) Dipak Panigrahy et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain tissue saving effects by single-dose intralesional administration of Neuroprotectin D1 on experimental focal penetrating brain injury in rats

(2019) Rand Wilcox Vanden Berg et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial)

(2019) Joel L. Ramirez et al.   JOURNAL OF SURGICAL RESEARCH

Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy

(2019) Xin Luo et al.   Frontiers in Pharmacology

Resolvin E3 attenuates allergic airway inflammation via the interleukin-23–interleukin-17A pathway

(2019) Makiko Sato et al.   FASEB JOURNAL

Resolvin D1 (RvD1) and maresin 1 (Mar1) contribute to human macrophage control of M. tuberculosis infection while resolving inflammation

(2019) Andy Ruiz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis

(2019) Tianye Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of weight loss on neutrophil resolvins in the metabolic syndrome

(2019) A. Barden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis

(2019) Romain A. Colas et al.   FASEB JOURNAL

Resolvin D1 promotes efferocytosis in aging by limiting senescent cell‐induced MerTK cleavage

(2019) Nicholas Rymut et al.   FASEB JOURNAL

Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

(2019) Gijs Kooij et al.   HAEMATOLOGICA

Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes

(2019) Bruce D. Levy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Liquid chromatography-coupled mass spectrometry analysis of glutathione conjugates of oxygenated polyunsaturated fatty acids

(2019) Stefanie Liening et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease

(2019) Paraskevi Krashia et al.   Nature Communications

Resolution metabolomes activated by hypoxic environment

(2019) Paul C. Norris et al.   Science Advances

Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses

(2019) Patricia R. Souza et al.   CIRCULATION RESEARCH

GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections

(2019) Magdalena B. Flak et al.   JOURNAL OF CLINICAL INVESTIGATION

First total syntheses of the pro-resolving lipid mediators 7(S),13(R),20(S)-Resolvin T1 and 7(S),13(R)-Resolvin T4

(2019) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes

(2019) Rupak Shivakoti et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration

(2018) Xavier de la Rosa et al.   AMERICAN JOURNAL OF PATHOLOGY

ERV1/ChemR23 Signaling Protects from Atherosclerosis by Modifying oxLDL Uptake and Phagocytosis in Macrophages

(2018) Andres Laguna-Fernandez et al.   CIRCULATION

Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPAIncrease Systemic Inflammation and Cardiovascular DiseaseNovelty and Significance

(2018) Romain A. Colas et al.   CIRCULATION RESEARCH

Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs . sunflower oil

(2018) C. Dawczynski et al.   CLINICAL NUTRITION

Potent Anti-Inflammatory and Pro-Resolving Effects of Anabasum in a Human Model of Self-Resolving Acute Inflammation

(2018) Madhur P. Motwani et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease

(2018) Alpdogan Kantarci et al.   EXPERIMENTAL NEUROLOGY

New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses

(2018) Nan Chiang et al.   FASEB JOURNAL

Dexamethasone induces ω3-derived immunoresolvents driving resolution of allergic airway inflammation

(2018) Katerina Pyrillou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia

(2018) Ho Pan Sham et al.   JOURNAL OF IMMUNOLOGY

Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair

(2018) Jason Hellmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Frontline Science: Specialized proresolving lipid mediators inhibit the priming and activation of the macrophage NLRP3 inflammasome

(2018) Aritz Lopategi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Frontline Science: Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation

(2018) Jeremy W. Winkler et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Stereocontrolled Synthesis of Resolvin D4

(2018) Masao Morita et al.   JOURNAL OF ORGANIC CHEMISTRY

The effect of n-3 fatty acids and coenzyme Q10 supplementation on neutrophil leukotrienes, mediators of inflammation resolution and myeloperoxidase in chronic kidney disease

(2018) Anne E. Barden et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression

(2018) Natsuko Saito-Sasaki et al.   Scientific Reports

Resolvin D2 Restrains Th1 Immunity and Prevents Alveolar Bone Loss in Murine Periodontitis

(2018) Gabriel Mizraji et al.   Frontiers in Immunology

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation

(2018) Sun-Yee Cheung et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment

(2018) Vasundhara Kain et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reduction of high-fat diet-induced liver pro-inflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: Involvement of resolvins RvE1/2 and RvD1/2

(2018) F. Echeverría et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Resolvin E3 attenuates lipopolysaccharide-induced depression-like behavior in mice

(2018) Satoshi Deyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Resolvin E1 attenuates murine psoriatic dermatitis

(2018) Yu Sawada et al.   Scientific Reports

Resolution of sickle cell disease–associated inflammation and tissue damage with 17R-resolvin D1

(2018) Alessandro Matte et al.   BLOOD

Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders

(2018) T. Yang et al.   BRITISH JOURNAL OF ANAESTHESIA

Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids

(2018) Charles N. Serhan et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 decreases abdominal aortic aneurysm formation by inhibiting NETosis in a mouse model

(2018) Michael Spinosa et al.   JOURNAL OF VASCULAR SURGERY

GPR18 expression on PMNs as biomarker for outcome in patient with sepsis

(2018) Lanqiu Zhang et al.   LIFE SCIENCES

Pathogenic stromal cells as therapeutic targets in joint inflammation

(2018) Stephanie G. Dakin et al.   Nature Reviews Rheumatology

Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain

(2018) Gang Chen et al.   NEURON

Combined administration of docosahexaenoic acid and thyroid hormone synergistically enhances rat liver levels of resolvins RvD1 and RvD2

(2018) Luis A. Videla et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation

(2018) Paul C. Norris et al.   Scientific Reports

Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease

(2018) John Pirault et al.   Frontiers in Pharmacology

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

(2017) Mary E. Walker et al.   FASEB JOURNAL

Resolvins suppress tumor growth and enhance cancer therapy

(2017) Megan L. Sulciner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury

(2017) Isaac Francos-Quijorna et al.   JOURNAL OF NEUROSCIENCE

Specialized pro-resolving mediators in cardiovascular diseases

(2017) Gabrielle Fredman et al.   MOLECULAR ASPECTS OF MEDICINE

Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation

(2017) Melody G. Duvall et al.   MOLECULAR ASPECTS OF MEDICINE

The role of pro-resolving lipid mediators in ocular diseases

(2017) Jessica Wei et al.   MOLECULAR ASPECTS OF MEDICINE

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology

(2017) Charles N. Serhan   MOLECULAR ASPECTS OF MEDICINE

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

(2017) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

Immune resolution mechanisms in inflammatory arthritis

(2017) Mauro Perretti et al.   Nature Reviews Rheumatology

Protectin D1n-3 DPAand resolvin D5n-3 DPAare effectors of intestinal protection

(2017) Thomas Gobbetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway

(2017) Giorgio Mottola et al.   PLoS One

Effects of aspirin-triggered resolvin D1 on peripheral blood mononuclear cells from patients with Chagas' heart disease

(2016) Haline Ogata et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins

(2016) Karoline G. Primdahl et al.   JOURNAL OF NATURAL PRODUCTS

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

The role of neutrophils in inflammation resolution

(2016) Hefin R. Jones et al.   SEMINARS IN IMMUNOLOGY

Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

(2016) Jeremy W. Winkler et al.   Scientific Reports

Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent

(2015) Sarah K. Orr et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling

(2015) Yanjun Gong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

Resolvin Infectious Inflammation by Targeting the Host Response

(2015) Craig R. Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Specialized Proresolving Mediator 17-HDHA Enhances the Antibody-Mediated Immune Response against Influenza Virus: A New Class of Adjuvant?

(2014) Sesquile Ramon et al.   JOURNAL OF IMMUNOLOGY

Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines

(2014) Hildur H. Arnardottir et al.   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

(2014) J. Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY

Novel n-3 Immunoresolvents: Structures and Actions

(2013) Jesmond Dalli et al.   Scientific Reports

Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke

(2012) Nicolas G. Bazan et al.   EXPERIMENTAL NEUROLOGY

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

(2012) Yosuke Isobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Novel Proresolving Aspirin-Triggered DHA Pathway

(2011) Charles N. Serhan et al.   CHEMISTRY & BIOLOGY

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE