Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

(2015) Amaia Rodríguez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Interleukin-33-p38 Kinase Axis Confers Memory T Helper 2 Cell Pathogenicity in the Airway

(2015) Yusuke Endo et al.   IMMUNITY

Targeting T cell metabolism for therapy

(2015) David O'Sullivan et al.   TRENDS IN IMMUNOLOGY

Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1

(2015) Yusuke Endo et al.   Cell Reports

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

(2014) Andrew N. Macintyre et al.   Cell Metabolism

Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling

(2014) Irfan J. Lodhi et al.   Cell Metabolism

Proatherogenic Conditions Promote Autoimmune T Helper 17 Cell Responses In Vivo

(2014) Hoyong Lim et al.   IMMUNITY

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

(2014) S. R. Jacobs et al.   JOURNAL OF IMMUNOLOGY

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Effector T cells require fatty acid metabolism during murine graft-versus-host disease

(2013) C. A. Byersdorfer et al.   BLOOD

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming

(2013) Kai Yang et al.   IMMUNITY

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

(2013) Yoko Kidani et al.   NATURE IMMUNOLOGY

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

(2013) Linda V Sinclair et al.   NATURE IMMUNOLOGY

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Metabolic checkpoints in activated T cells

(2012) Ruoning Wang et al.   NATURE IMMUNOLOGY

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Application of ChIP-Seq and Related Techniques to the Study of Immune Function

(2011) Daniel L. Northrup et al.   IMMUNITY

Eomesodermin Controls Interleukin-5 Production in Memory T Helper 2 Cells through Inhibition of Activity of the Transcription Factor GATA3

(2011) Yusuke Endo et al.   IMMUNITY

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peroxisome Proliferator-Activated Receptor γ Is Required for CD4 + T Cell-Mediated Lymphopenia-Associated Autoimmunity

(2011) William J. Housley et al.   JOURNAL OF IMMUNOLOGY

The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism

(2010) Jonathan D. Powell et al.   IMMUNITY

Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation

(2010) E. L. Carr et al.   JOURNAL OF IMMUNOLOGY

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

The TCR-mediated signaling pathways that control the direction of helper T cell differentiation

(2010) Toshinori Nakayama et al.   SEMINARS IN IMMUNOLOGY

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Th17 Differentiation by Epidermal Fatty Acid-Binding Protein

(2009) B. Li et al.   JOURNAL OF IMMUNOLOGY

Anergic T Cells Are Metabolically Anergic

(2009) Y. Zheng et al.   JOURNAL OF IMMUNOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory

(2009) Toshinori Nakayama et al.   SEMINARS IN IMMUNOLOGY