Extracellular Vesicles: An Emerging Mechanism Governing the Secretion and Biological Roles of Tenascin-C

Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine

(2021) Wumei Wei et al.   Frontiers in Pharmacology

Transfer of extracellular vesicle‐micro RNA controls germinal center reaction and antibody production

(2020) Lola Fernández‐Messina et al.   EMBO REPORTS

Tenascin-C promotes acute kidney injury to chronic kidney disease progression by impairing tubular integrity via αvβ6 integrin signaling.

(2020) Haili Zhu et al.   KIDNEY INTERNATIONAL

Pembrolizumab for Early Triple-Negative Breast Cancer

(2020) Peter Schmid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Matrix-Targeting Immunotherapy Controls Tumor Growth and Spread by Switching Macrophage Phenotype

(2020) Claire Deligne et al.   Cancer Immunology Research

Cargo crowding contributes to sorting stringency in COPII vesicles

(2020) Natalia Gomez-Navarro et al.   JOURNAL OF CELL BIOLOGY

Non-caveolar caveolins – duties outside the caves

(2020) Albert Pol et al.   JOURNAL OF CELL SCIENCE

Antifibrotic therapy to normalize the tumor microenvironment

(2020) Anette Hauge et al.   Journal of Translational Medicine

Tenascin-C Induces Phenotypic Changes in Fibroblasts to Myofibroblasts with High Contractility through the Integrin αvβ1/Transforming Growth Factor β/SMAD Signaling Axis in Human Breast Cancer

(2020) Daisuke Katoh et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation

(2020) Zhi-Ling Li et al.   Nature Communications

Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma

(2020) Caroline Spenlé et al.   Cancer Immunology Research

Tenascin-C preserves microglia surveillance and restricts leukocyte and, more specifically, T cell infiltration of the ischemic brain

(2020) Daniel Manrique-Castano et al.   BRAIN BEHAVIOR AND IMMUNITY

ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting

(2020) Lucas Albacete-Albacete et al.   JOURNAL OF CELL BIOLOGY

Fibroblast heterogeneity in tumor micro-environment: Role in immunosuppression and new therapies

(2020) Rana Mhaidly et al.   SEMINARS IN IMMUNOLOGY

Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors

(2020) Saveria Femminò et al.   VASCULAR PHARMACOLOGY

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis

(2020) Raffaele Strippoli et al.   Cell Death & Disease

Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion

(2019) Oliver D Yuan et al.   STEM CELLS AND DEVELOPMENT

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

(2019) Rongkun Li et al.   Molecular Cancer

Exosome-Mediated Metastasis: Communication from a Distance

(2019) Inbal Wortzel et al.   DEVELOPMENTAL CELL

Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance

(2019) Ladan Mashouri et al.   Molecular Cancer

Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling

(2019) Songying Qian et al.   OncoTargets and Therapy

Neutral Sphingomyelinase 2 (SMPD3)-Deficiency in Mice Causes Chondrodysplasia with Unimpaired Skeletal Mineralization

(2019) Wilhelm Stoffel et al.   AMERICAN JOURNAL OF PATHOLOGY

Exosomal MALAT1 derived from ox-LDL-treated endothelial cells induce neutrophil extracellular traps to aggravate atherosclerosis

(2019) Hailai Gao et al.   BIOLOGICAL CHEMISTRY

Tenascin-C increases lung metastasis by impacting blood vessel invasions

(2019) Zhen Sun et al.   MATRIX BIOLOGY

Targeting metabolic dysregulation for fibrosis therapy

(2019) Xiao Zhao et al.   NATURE REVIEWS DRUG DISCOVERY

Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection

(2019) Jake T. Mills et al.   Frontiers in Immunology

The therapy of idiopathic pulmonary fibrosis: what is next?

(2019) Vivien Somogyi et al.   European Respiratory Review

The many functions of ESCRTs

(2019) Marina Vietri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Shared and distinct mechanisms of fibrosis

(2019) Jörg H. W. Distler et al.   Nature Reviews Rheumatology

Inflammation in myocardial disease: From myocarditis to dilated cardiomyopathy

(2019) Kyoko Imanaka‐Yoshida   PATHOLOGY INTERNATIONAL

NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress

(2019) D. Höglinger et al.   Nature Communications

Designing a Tenascin-C-Inspired Short Bioactive Peptide Scaffold to Direct and Control Cellular Behavior

(2019) Pooja Sharma et al.   ACS Biomaterials-Science & Engineering

Immunomodulatory role of the extracellular matrix protein tenascin-C in neuroinflammation

(2019) Susanne Wiemann et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells

(2019) Bo Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Life in the lumen: The multivesicular endosome

(2019) Jean Gruenberg   TRAFFIC

ER-to-Golgi Transport: A Sizeable Problem

(2019) Janine McCaughey et al.   TRENDS IN CELL BIOLOGY

Ultrastructure and biological function of matrix vesicles in bone mineralization

(2018) Tomoka Hasegawa   HISTOCHEMISTRY AND CELL BIOLOGY

Tissue-associated self-antigens containing exosomes: Role in allograft rejection

(2018) Monal Sharma et al.   HUMAN IMMUNOLOGY

Tenascin C: A Potential Biomarker for Predicting the Severity of Coronary Atherosclerosis

(2018) Wen Gao et al.   Journal of Atherosclerosis and Thrombosis

Inflammation and fibrosis

(2018) Matthias Mack   MATRIX BIOLOGY

Liver fibrosis: Direct antifibrotic agents and targeted therapies

(2018) Detlef Schuppan et al.   MATRIX BIOLOGY

Exosomal MALAT1 derived from oxidized low-density lipoprotein-treated endothelial cells promotes M2 macrophage polarization

(2018) Chaoyang Huang et al.   Molecular Medicine Reports

Mechanisms and impact of altered tumour mechanics

(2018) Hamid Mohammadi et al.   NATURE CELL BIOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer

(2018) Jian Zheng et al.   HPB

TMED2/emp24 is required in both the chorion and the allantois for placental labyrinth layer development

(2018) Wenyang Hou et al.   DEVELOPMENTAL BIOLOGY

Therapeutic Potential of Mesenchymal Cell–Derived miRNA-150-5p–Expressing Exosomes in Rheumatoid Arthritis Mediated by the Modulation of MMP14 and VEGF

(2018) Zhe Chen et al.   JOURNAL OF IMMUNOLOGY

A positive feedback loop bi-stably activates fibroblasts

(2018) So-Young Yeo et al.   Nature Communications

Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity

(2018) Reza Mirzaei et al.   OncoImmunology

Fibronectin on the Surface of Extracellular Vesicles Mediates Fibroblast Invasion

(2018) Diptiman Chanda et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Endothelial FN (Fibronectin) Deposition by α5β1 Integrins Drives Atherogenic Inflammation

(2018) Zaki Al-Yafeai et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tenascin-C accelerates adverse ventricular remodelling after myocardial infarction by modulating macrophage polarization

(2018) Taizo Kimura et al.   CARDIOVASCULAR RESEARCH

Role of SMPD3 during Bone Fracture Healing and Regulation of its Expression

(2018) Garthiga Manickam et al.   MOLECULAR AND CELLULAR BIOLOGY

Caveolin-1-containing extracellular vesicles transport adhesion proteins and promote malignancy in breast cancer cell lines

(2018) America Campos et al.   Nanomedicine

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

(2018) Zhicheng Zeng et al.   Nature Communications

Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP

(2018) Roberto Moreno-Vicente et al.   Cell Reports

Extracellular Vesicles and Matrix Remodeling Enzymes: The Emerging Roles in Extracellular Matrix Remodeling, Progression of Diseases and Tissue Repair

(2018) Muhammad Nawaz et al.   Cells

TANGO1 assembles into rings around COPII coats at ER exit sites

(2017) Ishier Raote et al.   JOURNAL OF CELL BIOLOGY

Extracellular vesicles are integral and functional components of the extracellular matrix

(2017) Kirsi Rilla et al.   MATRIX BIOLOGY

Intra-tumor heterogeneity from a cancer stem cell perspective

(2017) Pramudita R. Prasetyanti et al.   Molecular Cancer

Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts

(2017) Fengming Yang et al.   Molecular Cancer

Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis

(2017) Bin Zheng et al.   MOLECULAR THERAPY

Exosome secretion promotes chemotaxis of cancer cells

(2017) Bong Hwan Sung et al.   Cell Adhesion & Migration

Functional importance of lysyl oxidase family propeptide regions

(2017) Philip C. Trackman   Journal of Cell Communication and Signaling

Exosomes Derived from HIV-1 Infected DCs Mediate Viral trans-Infection via Fibronectin and Galectin-3

(2017) Rutuja Kulkarni et al.   Scientific Reports

Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling

(2016) Jennifer H. Benbow et al.   AMERICAN JOURNAL OF PATHOLOGY

Periostin promotes secretion of fibronectin from the endoplasmic reticulum

(2016) Isao Kii et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

COP-coated vesicles

(2016) Natalia Gomez-Navarro et al.   CURRENT BIOLOGY

Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions

(2016) Jennifer Alexander et al.   CURRENT OPINION IN CELL BIOLOGY

Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-κB in endothelial cells

(2016) Norina Tang et al.   FASEB JOURNAL

Tenascin-C at a glance

(2016) Kim S. Midwood et al.   JOURNAL OF CELL SCIENCE

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

(2016) Charlotte Lawson et al.   JOURNAL OF ENDOCRINOLOGY

Fibronectin-Containing Extracellular Vesicles Protect Melanocytes against Ultraviolet Radiation-Induced Cytotoxicity

(2016) Bum-Ho Bin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dual function of cTAGE5 in collagen export from the endoplasmic reticulum

(2016) Tomoya Tanabe et al.   MOLECULAR BIOLOGY OF THE CELL

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Tenascin C perpetuates tissue fibrosis

(2016) Dario Ummarino   Nature Reviews Rheumatology

The IL-1 cytokine family and its role in inflammation and fibrosis in the lung

(2016) L. A. Borthwick   Seminars in Immunopathology

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis

(2016) Raffaele Strippoli et al.   Stem Cells International

Mechanism of Fibronectin Binding to Human Trabecular Meshwork Exosomes and Its Modulation by Dexamethasone

(2016) W. Michael Dismuke et al.   PLoS One

The Pathway of Collagen Secretion

(2015) Vivek Malhotra et al.   Annual Review of Cell and Developmental Biology

Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery WallSignificance

(2015) Lasse Bach Steffensen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immunomodulatory role of microRNAs transferred by extracellular vesicles

(2015) Lola Fernández-Messina et al.   BIOLOGY OF THE CELL

Matrix vesicles: Are they anchored exosomes?

(2015) Irving M. Shapiro et al.   BONE

Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

(2015) A. N. Kapustin et al.   CIRCULATION RESEARCH

Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration

(2015) Jingli Cao et al.   DEVELOPMENT

Tenascin-C: Its functions as an integrin ligand

(2015) Richard P. Tucker et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions

(2015) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration

(2015) Ruisi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2

(2015) Olivier G. de Jong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Exosomes and their roles in immune regulation and cancer

(2015) David W. Greening et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

Tenascin C in metastasis: A view from the invasive front

(2015) Camille M Lowy et al.   Cell Adhesion & Migration

Tenascin-C and integrins in cancer

(2015) Toshimichi Yoshida et al.   Cell Adhesion & Migration

Tenascins in fibrotic disorders—from bench to bedside

(2015) M Kasprzycka et al.   Cell Adhesion & Migration

Tenascin-X: beyond the architectural function

(2015) Ulrich Valcourt et al.   Cell Adhesion & Migration

The evolution of tenascins and fibronectin

(2015) Josephine C Adams et al.   Cell Adhesion & Migration

Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice

(2015) Min Zhu et al.   Scientific Reports

AngioMatrix, a signature of the tumor angiogenic switch-specific matrisome, correlates with poor prognosis for glioma and colorectal cancer patients

(2015) Benoit Langlois et al.   Oncotarget

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Tenascin-C Signaling in melanoma

(2014) Hanshuang Shao et al.   Cell Adhesion & Migration

Tenascin-C: Form versus function

(2014) Sean P Giblin et al.   Cell Adhesion & Migration

Tenascin-C and mechanotransduction in the development and diseases of cardiovascular system

(2014) Kyoko Imanaka-Yoshida et al.   Frontiers in Physiology

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

Trafficking mechanisms of extracellular matrix macromolecules: Insights from vertebrate development and human diseases

(2013) Gokhan Unlu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition

(2013) Emily C. Benesh et al.   MOLECULAR BIOLOGY OF THE CELL

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

(2013) Anand Ramteke et al.   MOLECULAR CARCINOGENESIS

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components

(2013) Hong Ji et al.   PROTEOMICS

Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

(2013) Falk Saupe et al.   Cell Reports

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Binding of αvβ1 and αvβ6 integrins to tenascin-C induces epithelial–mesenchymal transition-like change of breast cancer cells

(2013) D Katoh et al.   Oncogenesis

Deletion of tenascin-C gene exacerbates atherosclerosis and induces intraplaque hemorrhage in Apo-E-deficient mice

(2012) Lai Wang et al.   CARDIOVASCULAR PATHOLOGY

The evolution of metazoan extracellular matrix

(2012) Richard O. Hynes   JOURNAL OF CELL BIOLOGY

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

(2012) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

A translational study of urine miRNAs in acute myocardial infarction

(2012) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS

(2012) Michelle Demory Beckler et al.   MOLECULAR & CELLULAR PROTEOMICS

Tenascin-C produced by oxidized LDL-stimulated macrophages increases foam cell formation through toll-like receptor-4

(2012) Rui Liu et al.   MOLECULES AND CELLS

Ubiquitin-dependent regulation of COPII coat size and function

(2012) Lingyan Jin et al.   NATURE

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells

(2012) B Li et al.   ONCOGENE

Tenascin C Induces Epithelial-Mesenchymal Transition–Like Change Accompanied by SRC Activation and Focal Adhesion Kinase Phosphorylation in Human Breast Cancer Cells

(2011) Keiki Nagaharu et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumor Cell Cross Talk with Tumor-Associated Leukocytes Leads to Induction of Tumor Exosomal Fibronectin and Promotes Tumor Progression

(2011) ZhongBin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Trophoblast-Derived Exosomal Fibronectin Induces Pro-Inflammatory Il-1β Production by Macrophages

(2011) Safinur Atay et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The role of tenascin C in cardiovascular disease

(2011) Jonathan Golledge et al.   CARDIOVASCULAR RESEARCH

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Advances in tenascin-C biology

(2011) Kim S. Midwood et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cortactin Controls Cell Motility and Lamellipodial Dynamics by Regulating ECM Secretion

(2011) Bong Hwan Sung et al.   CURRENT BIOLOGY

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Global defects in collagen secretion in aMia3/TANGO1knockout mouse

(2011) Deanna G. Wilson et al.   JOURNAL OF CELL BIOLOGY

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

(2011) M. A. Antonyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Assembly of Fibronectin Extracellular Matrix

(2010) Purva Singh et al.   Annual Review of Cell and Developmental Biology

Survivin is released from cancer cells via exosomes

(2010) Salma Khan et al.   APOPTOSIS

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

The Evolution of Extracellular Matrix

(2010) Suat Özbek et al.   MOLECULAR BIOLOGY OF THE CELL

Williams–Beuren Syndrome

(2010) Barbara R. Pober   NEW ENGLAND JOURNAL OF MEDICINE

Sec24D-Dependent Transport of Extracellular Matrix Proteins Is Required for Zebrafish Skeletal Morphogenesis

(2010) Swapnalee Sarmah et al.   PLoS One

The Collagen Family

(2010) S. Ricard-Blum   Cold Spring Harbor Perspectives in Biology

Active Uptake of Dendritic Cell-Derived Exovesicles by Epithelial Cells Induces the Release of Inflammatory Mediators through a TNF-α-Mediated Pathway

(2009) Carolina Obregon et al.   AMERICAN JOURNAL OF PATHOLOGY

Collagens

(2009) Marion K. Gordon et al.   CELL AND TISSUE RESEARCH

Genetic Evidence Supporting a Critical Role of Endothelial Caveolin-1 during the Progression of Atherosclerosis

(2009) Carlos Fernández-Hernando et al.   Cell Metabolism

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

Extracellular Matrix Molecules: Potential Targets in Pharmacotherapy

(2009) H. Jarvelainen et al.   PHARMACOLOGICAL REVIEWS

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

(2009) Sophie Viaud et al.   PLoS One

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

Caveolin-1-dependent  1 integrin endocytosis is a critical regulator of fibronectin turnover

(2008) F. Shi et al.   JOURNAL OF CELL SCIENCE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE