Exosome secretion promotes chemotaxis of cancer cells

miR-146b-5p within BCR-ABL1-Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells

(2016) H.-M. Zhang et al.   CANCER RESEARCH

Cortactin promotes exosome secretion by controlling branched actin dynamics

(2016) Seema Sinha et al.   JOURNAL OF CELL BIOLOGY

Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation

(2016) Laura M. Desrochers et al.   Nature Communications

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

(2016) Andrew J. McKenzie et al.   Cell Reports

Exosomes Mediate LTB4 Release during Neutrophil Chemotaxis

(2016) Ritankar Majumdar et al.   PLOS BIOLOGY

Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome

(2015) Arun Cumpelik et al.   ANNALS OF THE RHEUMATIC DISEASES

The αvβ6Integrin Is Transferred Intercellularly via Exosomes

(2015) Carmine Fedele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAL-1 controls multivesicular body biogenesis and exosome secretion

(2015) Vincent Hyenne et al.   JOURNAL OF CELL BIOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

(2015) Charles P. Lai et al.   Nature Communications

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

Host Matrix Modulation by Tumor Exosomes Promotes Motility and Invasiveness

(2015) Wei Mu et al.   NEOPLASIA

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration

(2014) Liang Ma et al.   CELL RESEARCH

Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12

(2014) Stephen Douglass et al.   JOURNAL OF PATHOLOGY

CXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathways

(2014) Tammy Sobolik et al.   MOLECULAR BIOLOGY OF THE CELL

Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal

(2014) Andrew J. Muinonen-Martin et al.   PLOS BIOLOGY

Exosomes

(2013) Huang-Ge Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of CXCR4–CXCL12 chemotaxis in melanoma by AMD11070

(2013) G O'Boyle et al.   BRITISH JOURNAL OF CANCER

Proinflammatory role of epithelial cell–derived exosomes in allergic airway inflammation

(2013) Ankur Kulshreshtha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Hrs- and CD63-Dependent Competing Mechanisms Make Different Sized Endosomal Intraluminal Vesicles

(2013) James R. Edgar et al.   TRAFFIC

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

μ-Slide Chemotaxis: A new chamber for long-term chemotaxis studies

(2011) Pamela Zengel et al.   BMC CELL BIOLOGY

Cortactin Controls Cell Motility and Lamellipodial Dynamics by Regulating ECM Secretion

(2011) Bong Hwan Sung et al.   CURRENT BIOLOGY

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine

(2011) T. Chen et al.   JOURNAL OF IMMUNOLOGY

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

(2010) Julia Esser et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Directional sensing during chemotaxis

(2008) Christopher Janetopoulos et al.   FEBS LETTERS

Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge

(2008) Paul W. Kriebel et al.   JOURNAL OF CELL BIOLOGY

Itinerant exosomes: emerging roles in cell and tissue polarity

(2008) Aparna Lakkaraju et al.   TRENDS IN CELL BIOLOGY