Tenascin C in metastasis: A view from the invasive front

Metastatic Stem Cells: Sources, Niches, and Vital Pathways

(2014) Thordur Oskarsson et al.   Cell Stem Cell

Tenascin-C-derived Peptide TNIIIA2 Highly Enhances Cell Survival and Platelet-derived Growth Factor (PDGF)-dependent Cell Proliferation through Potentiated and Sustained Activation of Integrin α5β1

(2014) Rika Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretome Analysis of Testicular Peritubular Cells: A Window into the Human Testicular Microenvironment and the Spermatogonial Stem Cell Niche in Man

(2014) Florian Flenkenthaler et al.   JOURNAL OF PROTEOME RESEARCH

Tenascins in stem cell niches

(2014) Ruth Chiquet-Ehrismann et al.   MATRIX BIOLOGY

SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients

(2014) Irem Gurbuz et al.   Molecular Cancer

Emerging biomarkers in head and neck cancer in the era of genomics

(2014) Hyunseok Kang et al.   Nature Reviews Clinical Oncology

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

(2014) Mads A Jensen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis

(2013) Vanessa Y Tan et al.   BMC Medicine

PDGF and TGF-β promote tenascin-C expression in subepithelial myofibroblasts and contribute to intestinal mucosal protection in mice

(2013) M S Islam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Origins of Metastatic Traits

(2013) Sakari Vanharanta et al.   CANCER CELL

The molecular composition of the metastatic niche

(2013) Arnaud Descot et al.   EXPERIMENTAL CELL RESEARCH

The role of Tenascin C in the lymphoid progenitor cell niche

(2013) Sarah L. Ellis et al.   EXPERIMENTAL HEMATOLOGY

Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration

(2013) R. P. Tucker et al.   JOURNAL OF CELL SCIENCE

Cutaneous melanoma

(2013) Alexander MM Eggermont et al.   LANCET

Extracellular matrix proteins: A positive feedback loop in lung fibrosis?

(2013) Marjolein E. Blaauboer et al.   MATRIX BIOLOGY

Lung cancer chemoprevention: current status and future prospects

(2013) Robert L. Keith et al.   Nature Reviews Clinical Oncology

Preferential Biological Processes in the Human Limbus by Differential Gene Profiling

(2013) Martin N. Nakatsu et al.   PLoS One

Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

(2013) Falk Saupe et al.   Cell Reports

Binding of αvβ1 and αvβ6 integrins to tenascin-C induces epithelial–mesenchymal transition-like change of breast cancer cells

(2013) D Katoh et al.   Oncogenesis

Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration

(2012) A. Nakamura-Ishizu et al.   BLOOD

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Melanoma Cell Invasiveness Is Promoted at Least in Part by the Epidermal Growth Factor–Like Repeats of Tenascin-C

(2012) Jelena Grahovac et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tenascin C Induces Epithelial-Mesenchymal Transition–Like Change Accompanied by SRC Activation and Focal Adhesion Kinase Phosphorylation in Human Breast Cancer Cells

(2011) Keiki Nagaharu et al.   AMERICAN JOURNAL OF PATHOLOGY

The extracellular matrix: an active or passive player in fibrosis?

(2011) Thomas N. Wight et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

(2011) Lisha Patel et al.   BMC MUSCULOSKELETAL DISORDERS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Advances in tenascin-C biology

(2011) Kim S. Midwood et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extracellular matrix players in metastatic niches

(2011) Thordur Oskarsson et al.   EMBO JOURNAL

Different patterns of fibronectin and tenascin-C splice variants expression in primary and metastatic melanoma lesions

(2011) Katharina Frey et al.   EXPERIMENTAL DERMATOLOGY

Differential vascular expression and regulation of oncofetal tenascin-C and fibronectin variants in renal cell carcinoma (RCC): implications for an individualized angiogenesis-related targeted drug delivery

(2011) Kerstin Galler et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth

(2011) Ellen Van Obberghen-Schilling et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The roles of fascins in health and disease

(2011) Yosuke Hashimoto et al.   JOURNAL OF PATHOLOGY

Interactions between cancer stem cells and their niche govern metastatic colonization

(2011) Ilaria Malanchi et al.   NATURE

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

(2011) Thordur Oskarsson et al.   NATURE MEDICINE

VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

(2011) J. T. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

A comparative immunofluorescence analysis of three clinical-stage antibodies in head and neck cancer

(2011) Kathrin Schwager et al.   Head and Neck Optical Diagnostics Society

Tenascin-C deficiency attenuates TGF-β-mediated fibrosis following murine lung injury

(2010) William A. Carey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gemcitabine Resistance Induced by Interaction between Alternatively Spliced Segment of Tenascin-C and Annexin A2 in Pancreatic Cancer Cells

(2010) Xiao-Guang Gong et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma

(2010) Zhuomin Wang et al.   BIOMARKERS

The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion

(2010) Ang Li et al.   CURRENT BIOLOGY

14-3-3  Regulates Ubiquitin-Independent Proteasomal Degradation of p21, a Novel Mechanism of p21 Downregulation in Breast Cancer

(2010) B. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population

(2010) M Fukunaga-Kalabis et al.   ONCOGENE

The regulation of tenascin expression by tissue microenvironments

(2009) Richard P. Tucker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

From mechanotransduction to extracellular matrix gene expression in fibroblasts

(2009) Matthias Chiquet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tenascin-C Is a Novel RBPJ -Induced Target Gene for Notch Signaling in Gliomas

(2009) B. Sivasankaran et al.   CANCER RESEARCH

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

Incorporation of Tenascin-C into the Extracellular Matrix by Periostin Underlies an Extracellular Meshwork Architecture

(2009) Isao Kii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

B and C domain containing tenascin-C: urinary markers for invasiveness of urothelial carcinoma of the urinary bladder?

(2009) Petra Richter et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

(2009) Pierre Farmer et al.   NATURE MEDICINE

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

The role of tenascin-C in tissue injury and tumorigenesis

(2009) Kim S. Midwood et al.   Journal of Cell Communication and Signaling

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Association of an Extracellular Matrix Gene Cluster with Breast Cancer Prognosis and Endocrine Therapy Response

(2008) J. Helleman et al.   CLINICAL CANCER RESEARCH

Jak2/Stat5 Signaling in Mammogenesis, Breast Cancer Initiation and Progression

(2008) Kay-Uwe Wagner et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Comparative immunohistochemistry of L19 and F16 in non-small cell lung cancer and mesothelioma: Two human antibodies investigated in clinical trials in patients with cancer

(2008) Marta Pedretti et al.   LUNG CANCER

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

An Induction Gene Trap Screen in Neural Stem Cells Reveals an Instructive Function of the Niche and Identifies the Splicing Regulator Sam68 as a Tenascin-C-Regulated Target Gene

(2008) Sören Moritz et al.   STEM CELLS