Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS

Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes

(2012) Hee Doo Lee et al.   FASEB JOURNAL

Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated with worse overall survival

(2012) D. J. Hartman et al.   INTERNATIONAL JOURNAL OF CANCER

GeLC-MRM Quantitation of Mutant KRAS Oncoprotein in Complex Biological Samples

(2012) Patrick J. Halvey et al.   JOURNAL OF PROTEOME RESEARCH

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Supporting tool suite for production proteomics

(2011) Z.-Q. Ma et al.   BIOINFORMATICS

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Regulation of homeostasis and oncogenesis in the intestinal epithelium by Ras

(2011) Sergia Velho et al.   EXPERIMENTAL CELL RESEARCH

Proteomic Consequences of a Single Gene Mutation in a Colorectal Cancer Model

(2011) Patrick J. Halvey et al.   JOURNAL OF PROTEOME RESEARCH

Methods for Peptide and Protein Quantitation by Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry

(2011) Haixia Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Regulating the regulator: post-translational modification of RAS

(2011) Ian M. Ahearn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutant proteins as cancer-specific biomarkers

(2011) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitination of K-Ras Enhances Activation and Facilitates Binding to Select Downstream Effectors

(2011) A. T. Sasaki et al.   Science Signaling

H-ras resides on clathrin-independent ARF6 vesicles that harbor little RAF-1, but not on clathrin-dependent endosomes

(2010) Jodi McKay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy

(2010) Tian Tian et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

Comparative Shotgun Proteomics Using Spectral Count Data and Quasi-Likelihood Modeling

(2010) Ming Li et al.   JOURNAL OF PROTEOME RESEARCH

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes

(2009) Rui Zhan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rasosomes spread Ras signals from plasma membrane ‘hotspots’

(2009) Merav Kofer-Geles et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Advancing science and technology via 3D culture on basement membrane matrix

(2009) G. Benton et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells

(2009) Junichi Soh et al.   PLoS One

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Difference gel electrophoresis analysis of Ras‐transformed fibroblast cell‐derived exosomes

(2008) Hong Ji et al.   ELECTROPHORESIS

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS

Exosome Function: From Tumor Immunology to Pathogen Biology

(2008) Jeffrey S. Schorey et al.   TRAFFIC