Functional importance of lysyl oxidase family propeptide regions

Uncovering the role of nuclear Lysyl oxidase (LOX) in advanced high grade serous ovarian cancer

(2017) Marta De Donato et al.   GYNECOLOGIC ONCOLOGY

Proteolytic processing of lysyl oxidase–like-2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV

(2017) Alberto J. López-Jiménez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer

(2017) Avelino Fraga et al.   BMC Urology

LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway

(2017) Eva P. Cuevas et al.   Scientific Reports

TGF-β1 promotes linear invadosome formation in hepatocellular carcinoma cells, through DDR1 up-regulation and collagen I cross-linking

(2016) Zakaria Ezzoukhry et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer

(2016) Philip C. Trackman   EXPERT OPINION ON THERAPEUTIC TARGETS

Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone

(2016) Philip C. Trackman   MATRIX BIOLOGY

Loss of fibulin-4 results in abnormal collagen fibril assembly in bone, caused by impaired lysyl oxidase processing and collagen cross-linking

(2016) Takako Sasaki et al.   MATRIX BIOLOGY

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa

(2016) Takako Sasaki et al.   MATRIX BIOLOGY

ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis

(2016) D H Peng et al.   ONCOGENE

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

(2016) Benjamin Le Calvé et al.   Oncotarget

Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population

(2016) Guoli Wang et al.   International Journal of Environmental Research and Public Health

Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting fromEFEMP2mutations

(2015) Christina L. Papke et al.   HUMAN MOLECULAR GENETICS

Fibulin-4 E57K Knock-in Mice Recapitulate Cutaneous, Vascular and Skeletal Defects of Recessive Cutis Laxa 1B with both Elastic Fiber and Collagen Fibril Abnormalities

(2015) Olga Igoucheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide

(2015) Gokhan Baris Ozdener et al.   Molecular Oncology

Human copper-dependent amine oxidases

(2014) Joel Finney et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human lysyl oxidase-like 2

(2014) Hee-Jung Moon et al.   BIOORGANIC CHEMISTRY

Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer

(2014) Meimei Bu et al.   DNA AND CELL BIOLOGY

Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma

(2014) Carmen Chak-Lui Wong et al.   HEPATOLOGY

Alternative promoter activation leads to the expression of a novel human lysyl oxidase variant that functions as an amine oxidase

(2014) SEONKWAN KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lysyl oxidase rs1800449 polymorphism and cancer risk among Asians: evidence from a meta-analysis and a case–control study of colorectal cancer

(2014) Xueren Gao et al.   MOLECULAR GENETICS AND GENOMICS

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways

(2014) M V Bais et al.   ONCOGENE

Association of the G473A Polymorphism and Expression of Lysyl Oxidase with Breast Cancer Risk and Survival in European Women: A Hospital-Based Case-Control Study

(2014) Andrea Friesenhengst et al.   PLoS One

LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition

(2014) E. P. Cuevas et al.   Biology Open

Lysyl oxidase genetic variants and the prognosis of glioma

(2013) Song Han et al.   APMIS

Association between Lysyl Oxidase G473A Polymorphism and Ovarian Cancer in the Han Chinese Population

(2013) X Wang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Correction: The Unique Structure of the Apicoplast Genome of the Rodent Malaria Parasite Plasmodium chabaudi chabaudi

(2013) Shigeharu Sato et al.   PLoS One

Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer

(2012) Shulamit Sebban et al.   CLINICAL & EXPERIMENTAL METASTASIS

Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Ovarian Cancer

(2012) Jie Wu et al.   Genetic Testing and Molecular Biomarkers

Decreased expression of elastin, fibulin-5 and lysyl oxidase-like 1 in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse

(2012) Bai-hui Zhao et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer

(2012) Weiwei Shi et al.   TUMOR BIOLOGY

Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population

(2011) JUNG HWAN YOON et al.   APMIS

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

(2011) M. Bignon et al.   BLOOD

The Enzymatic Activity of Lysyl Oxidas-like-2 (LOXL2) Is Not Required for LOXL2-induced Inhibition of Keratinocyte Differentiation

(2011) Jennie Lugassy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Megakaryocyte Expansion and Bone Marrow Fibrosis by Lysyl Oxidase

(2011) Alexia Eliades et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lysyl Oxidase Propeptide Interacts with the Receptor-Type Protein Tyrosine Phosphatase Kappa and Inhibits  -Catenin Transcriptional Activity in Lung Cancer Cells

(2011) N. Sanchez-Morgan et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ras Signaling Inhibitor LOX-PP Interacts with Hsp70 and c-Raf To Reduce Erk Activation and Transformed Phenotype of Breast Cancer Cells

(2011) S. Sato et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of Recombinant Lysyl Oxidase Propeptide

(2010) Siddharth R. Vora et al.   BIOCHEMISTRY

Lysyl Oxidase 473 G>A Polymorphism and Breast Cancer Susceptibility in Chinese Han Population

(2010) Jinghua Ren et al.   DNA AND CELL BIOLOGY

Modulation of Lysyl Oxidase-like 2 Enzymatic Activity by an Allosteric Antibody Inhibitor

(2010) Hector M. Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl Oxidase Propeptide Inhibits FGF-2-induced Signaling and Proliferation of Osteoblasts

(2010) Siddharth R. Vora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between Periostin and BMP-1 Promotes Proteolytic Activation of Lysyl Oxidase

(2010) Takumi Maruhashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Lysyl Oxidase Propeptide in Secretion and Enzyme Activity

(2010) Jessica L. Grimsby et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nna1 Mediates Purkinje Cell Dendritic Development via Lysyl Oxidase Propeptide and NF-κB Signaling

(2010) Jianxue Li et al.   NEURON

A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer

(2009) C. Min et al.   CANCER RESEARCH

Fibronectin Binds and Enhances the Activity of Bone Morphogenetic Protein 1

(2009) Guorui Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling

(2009) A H Palamakumbura et al.   ONCOGENE

Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase

(2009) Masahito Horiguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Casin Breast Cancer Cells

(2008) Yingshe Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Periostin is essential for cardiac healingafter acute myocardial infarction

(2008) Masashi Shimazaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities

(2008) Shulamit Sebban et al.   VIRCHOWS ARCHIV