Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components

CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

(2015) Thorsten Jung et al.   NEOPLASIA

Extracellular vesicles - vehicles that spread cancer genes

(2012) Janusz Rak et al.   BIOESSAYS

The metastatic niche and stromal progression

(2012) Jonathan P. Sleeman   CANCER AND METASTASIS REVIEWS

Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

(2012) Bradley M. Coleman et al.   FASEB JOURNAL

Ultrastructural Evidence of Exosome Secretion by Progenitor Cells in Adult Mouse Myocardium and Adult Human Cardiospheres

(2012) Lucio Barile et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Biological and clinical relevance of stem cells in pancreatic adenocarcinoma

(2012) Zeshaan A Rasheed et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids

(2012) Bow J. Tauro et al.   MOLECULAR & CELLULAR PROTEOMICS

Get on the exosome bus with ALIX

(2012) James H. Hurley et al.   NATURE CELL BIOLOGY

Rap2A links intestinal cell polarity to brush border formation

(2012) Martijn Gloerich et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells

(2012) U. Putz et al.   Science Signaling

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

Exosomes as intercellular signalosomes and pharmacological effectors

(2011) Michel Record et al.   BIOCHEMICAL PHARMACOLOGY

Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis

(2011) Sanyukta Rana et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A TeNaCious Foundation for the Metastatic Niche

(2011) Irina Matei et al.   CANCER CELL

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis

(2011) Chenjie Yang et al.   Clinical & Developmental Immunology

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Increased membrane shedding – indicated by an elevation of CD133-enriched membrane particles – into the CSF in partial epilepsy

(2011) Hagen B. Huttner et al.   EPILEPSY RESEARCH

Lipid rafts: signaling and sorting platforms of cells and their roles in cancer

(2011) Simon Staubach et al.   Expert Review of Proteomics

Tumor microenvironment and progression

(2011) Harold F. Dvorak et al.   JOURNAL OF SURGICAL ONCOLOGY

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

(2011) Thordur Oskarsson et al.   NATURE MEDICINE

The biology of head and neck cancer stem cells

(2011) Zhaocheng Zhang et al.   ORAL ONCOLOGY

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

CD133 and membrane microdomains: Old facets for future hypotheses

(2011) Christine A Fargeas   WORLD JOURNAL OF GASTROENTEROLOGY

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

(2011) J D Lathia et al.   Cell Death & Disease

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

RACK1 down-regulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells

(2010) M. Cecilia Subauste et al.   CANCER BIOLOGY & THERAPY

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development

(2010) Hiroshi Kawabe et al.   NEURON

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand

(2010) Nai-Ying Yang et al.   Pigment Cell & Melanoma Research

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Membrane Microvesicles as Actors in the Establishment of a Favorable Prostatic Tumoral Niche: A Role for Activated Fibroblasts and CX3CL1-CX3CR1 Axis

(2009) D. Castellana et al.   CANCER RESEARCH

Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation

(2009) J.-L. Qu et al.   DIGESTIVE AND LIVER DISEASE

The kinase TNIK is an essential activator of Wnt target genes

(2009) Tokameh Mahmoudi et al.   EMBO JOURNAL

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Antimetastatic Role of Smad4 Signaling in Colorectal Cancer

(2009) Bixiang Zhang et al.   GASTROENTEROLOGY

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Claudin-7 Regulates EpCAM-Mediated Functions in Tumor Progression

(2009) T. Nubel et al.   MOLECULAR CANCER RESEARCH

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7

(2009) Simon Staubach et al.   PROTEOMICS

Secretome-based proteomics reveals sulindac-modulated proteins released from colon cancer cells

(2009) Hong Ji et al.   Proteomics Clinical Applications

The reggie/flotillin connection to growth

(2009) Claudia A.O. Stuermer   TRENDS IN CELL BIOLOGY

Cancer and the tumor microenvironment: a review of an essential relationship

(2008) Flaubert Mbeunkui et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Role of CD133 in Normal Human Prostate Stem Cells and Malignant Cancer-Initiating Cells

(2008) D. J. Vander Griend et al.   CANCER RESEARCH

Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants

(2008) Réjean Cantin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma

(2008) O Ndozangue-Touriguine et al.   ONCOGENE

The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic Melanoma

(2008) Germana Rappa et al.   STEM CELLS

A review of the S100 proteins in cancer

(2007) I. Salama et al.   EJSO