Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis

Mesothelial-to-Mesenchymal Transition Contributes to the Generation of Carcinoma-Associated Fibroblasts in Locally Advanced Primary Colorectal Carcinomas

(2020) Carlos H. Gordillo et al.   Cancers

Rac-GTPase promotes fibrotic TGF-β1 signaling and chronic kidney disease via EGFR, p53, and Hippo/YAP/TAZ pathways

(2019) Samik Patel et al.   FASEB JOURNAL

Mechanochemical Feedback Loops in Development and Disease

(2019) Edouard Hannezo et al.   CELL

Functional molecules in mesothelial-to-mesenchymal transition revealed by transcriptome analyses

(2018) Sara Namvar et al.   JOURNAL OF PATHOLOGY

The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

(2018) Andrew J. McKenzie et al.   Scientific Reports

ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer

(2018) Teijo Pellinen et al.   Scientific Reports

Matrix Stiffness: the Conductor of Organ Fibrosis

(2018) Alba Santos et al.   Current Rheumatology Reports

SanXoT: a modular and versatile package for the quantitative analysis of high-throughput proteomics experiments

(2018) Marco Trevisan-Herraz et al.   BIOINFORMATICS

The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae

(2018) Valentina Rausch et al.   CURRENT BIOLOGY

Emerging roles of YAP/TAZ in lung physiology and diseases

(2018) Haojun Xie et al.   LIFE SCIENCES

Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers

(2018) Jonathan M. Tsai et al.   Science Translational Medicine

Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP

(2018) Roberto Moreno-Vicente et al.   Cell Reports

Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer

(2017) Hsiang-Hsi Ling et al.   EXPERIMENTAL CELL RESEARCH

Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer

(2017) Angela Rynne-Vidal et al.   JOURNAL OF PATHOLOGY

La presión intraperitoneal en diálisis peritoneal

(2017) Vicente Pérez Díaz et al.   NEFROLOGIA

Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients

(2017) Vicente Ruiz-Carpio et al.   Scientific Reports

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Mesothelial cells and peritoneal homeostasis

(2016) Steven Eugene Mutsaers et al.   FERTILITY AND STERILITY

Integrin-mediated mechanotransduction

(2016) Zhiqi Sun et al.   JOURNAL OF CELL BIOLOGY

Mesothelial-to-mesenchymal transition in the pathogenesis of post-surgical peritoneal adhesions

(2016) Pilar Sandoval et al.   JOURNAL OF PATHOLOGY

YAP/TAZ Are Mechanoregulators of TGF- -Smad Signaling and Renal Fibrogenesis

(2016) S. G. Szeto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Novel Systems-Biology Algorithm for the Analysis of Coordinated Protein Responses Using Quantitative Proteomics

(2016) Fernando García-Marqués et al.   MOLECULAR & CELLULAR PROTEOMICS

Caveolae: One Function or Many?

(2016) Jade P.X. Cheng et al.   TRENDS IN CELL BIOLOGY

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis

(2016) Raffaele Strippoli et al.   Stem Cells International

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

(2015) Fei Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Caveolae - mechanosensitive membrane invaginations linked to actin filaments

(2015) A. Echarri et al.   JOURNAL OF CELL SCIENCE

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization

(2015) C Hwangbo et al.   ONCOGENE

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

(2014) R. Strippoli et al.   EMBO Molecular Medicine

General Statistical Framework for Quantitative Proteomics by Stable Isotope Labeling

(2014) Pedro Navarro et al.   JOURNAL OF PROTEOME RESEARCH

Revisiting Peptide Identification by High-Accuracy Mass Spectrometry: Problems Associated with the Use of Narrow Mass Precursor Windows

(2014) Elena Bonzon-Kulichenko et al.   JOURNAL OF PROTEOME RESEARCH

A Pathogenetic Role for Endothelin-1 in Peritoneal Dialysis-Associated Fibrosis

(2014) O. Busnadiego et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

(2014) Pedro M. Quirós et al.   Cell Reports

YAP forces fibroblasts to feel the tension

(2013) Ori Maller et al.   NATURE CELL BIOLOGY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis

(2013) R. P. G. ten Broek et al.   BMJ-British Medical Journal

TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth

(2012) Makiko Fujii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity

(2011) Rebecca L. Heise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

A Refined Method To Calculate False Discovery Rates for Peptide Identification Using Decoy Databases

(2009) Pedro Navarro et al.   JOURNAL OF PROTEOME RESEARCH

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF- B/Snail1 pathway

(2008) R. Strippoli et al.   Disease Models & Mechanisms

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Properties of Average Score Distributions of SEQUEST

(2008) Salvador Martínez-Bartolomé et al.   MOLECULAR & CELLULAR PROTEOMICS

TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY