Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis

Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29

(2015) Carla Cicchini et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

(2015) M. Fierro-Fernandez et al.   EMBO REPORTS

The expression profiling and ontology analysis of noncoding RNAs in peritoneal fibrosis induced by peritoneal dialysis fluid

(2015) Yanli Liu et al.   GENE

Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis

(2015) L. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10

(2015) Akira Onishi et al.   LABORATORY INVESTIGATION

Mast cell involvement in the progression of peritoneal fibrosis in rats with chronic renal failure

(2015) Itsuro Kazama et al.   NEPHROLOGY

T Helper 17/Regulatory T Cell Balance and Experimental Models of Peritoneal Dialysis-Induced Damage

(2015) Georgios Liappas et al.   Biomed Research International

A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid

(2015) E. Ferrantelli et al.   Biomed Research International

Mesothelial cells in tissue repair and fibrosis

(2015) Steven E. Mutsaers et al.   Frontiers in Pharmacology

Gremlin Promotes Peritoneal Membrane Injury in an Experimental Mouse Model and Is Associated with Increased Solute Transport in Peritoneal Dialysis Patients

(2014) Imad Siddique et al.   AMERICAN JOURNAL OF PATHOLOGY

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

(2014) R. Strippoli et al.   EMBO Molecular Medicine

Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

(2014) Ceri A. Fielding et al.   IMMUNITY

Astragalus membranaceus Inhibits Peritoneal Fibrosis via Monocyte Chemoattractant Protein (MCP)-1 and the Transforming Growth Factor-β1 (TGF-β1) Pathway in Rats Submitted to Peritoneal Dialysis

(2014) Zhenghong Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Pathogenetic Role for Endothelin-1 in Peritoneal Dialysis-Associated Fibrosis

(2014) O. Busnadiego et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-17A is a novel player in dialysis-induced peritoneal damage

(2014) Raquel Rodrigues-Díez et al.   KIDNEY INTERNATIONAL

MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis

(2014) Jian-Wen Yu et al.   LABORATORY INVESTIGATION

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases

(2014) Ivan Caiello et al.   PLoS One

Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis

(2013) Suman Karki et al.   FASEB JOURNAL

BMP-7 counteracting TGF-beta1 activities in organ fibrosis

(2013) Ralf Weiskirchen   Frontiers in Bioscience-Landmark

Differential expression of long non-coding RNAs in bleomycin-induced lung fibrosis

(2013) GUOHONG CAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis

(2013) Pilar Sandoval et al.   JOURNAL OF PATHOLOGY

The Potential Role of HMGB1 Release in Peritoneal Dialysis-Related Peritonitis

(2013) Shirong Cao et al.   PLoS One

The Noncoding RNA Expression Profile and the Effect of lncRNA AK126698 on Cisplatin Resistance in Non-Small-Cell Lung Cancer Cell

(2013) Yong Yang et al.   PLoS One

Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis

(2012) Michael Zeisberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

MicroRNAs and fibrosis

(2012) Vishal Patel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Retraction

(2012)   FASEB JOURNAL

The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription

(2012) Jelena Stanisavljevic et al.   JOURNAL OF CELL SCIENCE

The monocyte chemoattractant protein-1 (MCP-1)/CCR2 system is involved in peritoneal dialysis-related epithelial–mesenchymal transition of peritoneal mesothelial cells

(2012) Sun Ha Lee et al.   LABORATORY INVESTIGATION

Pathophysiological Changes to the Peritoneal Membrane during PD-Related Peritonitis: The Role of Mesothelial Cells

(2012) Susan Yung et al.   MEDIATORS OF INFLAMMATION

Twist overexpression promoted epithelial-to-mesenchymal transition of human peritoneal mesothelial cells under high glucose

(2012) C. Li et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells

(2012) Raffaele Strippoli et al.   PLoS One

TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling

(2012) Chris Hough et al.   PLoS One

miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1

(2011) Jingcheng Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs

(2011) F Garibaldi et al.   CELL DEATH AND DIFFERENTIATION

Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways

(2011) Olorunseun O. Ogunwobi et al.   CLINICAL & EXPERIMENTAL METASTASIS

The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α

(2011) Laura Santangelo et al.   HEPATOLOGY

Pathophysiology of the Peritoneal Membrane during Peritoneal Dialysis: The Role of Hyaluronan

(2011) Susan Yung et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response

(2011) Yoshimi Sekiguchi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Blocking TGF- 1 Protects the Peritoneal Membrane from Dialysate-Induced Damage

(2011) J. Loureiro et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors

(2011) Chantal S. Colmont et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

p38 maintains E-cadherin expression by modulating TAK1-NF- B during epithelial-to-mesenchymal transition

(2010) R. Strippoli et al.   JOURNAL OF CELL SCIENCE

The Pathophysiology of the Peritoneal Membrane

(2010) O. Devuyst et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Low-GDP peritoneal dialysis fluid ('balance') has less impact in vitro and ex vivo on epithelial-to-mesenchymal transition (EMT) of mesothelial cells than a standard fluid

(2010) M. A. Bajo et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure

(2010) Jesús Loureiro et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Treatment of Established Peritoneal Fibrosis by Gene Transfer of Smad7 in a Rat Model of Peritoneal Dialysis

(2009) Yanyan Sun et al.   AMERICAN JOURNAL OF NEPHROLOGY

Association between Markers of Inflammation, Fibrosis and Hypervolemia in Peritoneal Dialysis Patients

(2009) Azim S. Gangji et al.   BLOOD PURIFICATION

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyclooxygenase-2 Mediates Dialysate-Induced Alterations of the Peritoneal Membrane

(2009) L. S. Aroeira et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

HGF and BMP-7 Ameliorate High Glucose-Induced Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelium

(2009) M.-A Yu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Smad3-dependent and -independent pathways are involved in peritoneal membrane injury

(2009) Pranali Patel et al.   KIDNEY INTERNATIONAL

Altering peritoneal membrane function: removing the GAG?

(2009) D. J. Fraser et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Alterations in proteoglycan components and histopathology of the peritoneum in uraemic and peritoneal dialysis (PD) patients

(2009) S. Osada et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Impact of Uremia, Diabetes, and Peritoneal Dialysis Itself on the Pathogenesis of Peritoneal Sclerosis: A Quantitative Study of Peritoneal Membrane Morphology

(2008) K. Honda et al.   Clinical Journal of the American Society of Nephrology

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF- B/Snail1 pathway

(2008) R. Strippoli et al.   Disease Models & Mechanisms

Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression

(2008) Kristina E. Hoot et al.   JOURNAL OF CLINICAL INVESTIGATION

CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy

(2008) T. Q. Nguyen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effects of epithelial-to-mesenchymal transition on acute stress response in human peritoneal mesothelial cells

(2008) R. Vargha et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION