β-glucan, “the knight of health sector”: critical insights on physiochemical heterogeneities, action mechanisms and health implications

Changes in the Global Burden of Chronic Liver Diseases From 2012 to 2017: The Growing Impact of Nonalcoholic Fatty Liver Disease

(2020) James M. Paik et al.   HEPATOLOGY

Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway

(2020) Charng-Cherng Chyau et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Shaping the Innate Immune Response by Dietary Glucans: Any Role in the Control of Cancer?

(2020) Manuela Del Cornò et al.   Cancers

Bile acid-retention by native and modified oat and barley β-glucan

(2020) Elena Marasca et al.   CARBOHYDRATE POLYMERS

Soluble beta-glucan salecan improves vaginal infection of Candida albicans in mice

(2020) Xiaqing Sun et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

What is the effectiveness of beta-glucan for treatment of acute otitis media?

(2020) Erdem Atalay Cetinkaya et al.   Brazilian Journal of Otorhinolaryngology

β-Glucan Metabolic and Immunomodulatory Properties and Potential for Clinical Application

(2020) Emma J. Murphy et al.   Journal of Fungi

Radiation Degradation of β-Glucan Extracted from Brewer’s Yeast for Enhancing Growth Promotion and Immunostimulant Activities on Broilers

(2019) Nguyen Thanh Long et al.   International Journal of Polymer Science

Lifestyle interventions for non-alcoholic fatty liver disease

(2019) Idris Adewale Ahmed et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

β-Glucan-Based Wet Dressing for Cutaneous Wound Healing

(2019) Karthika Muthuramalingam et al.   Advances in Wound Care

Protein-Bound β-glucan from Coriolus Versicolor has Potential for Use Against Obesity

(2019) Xiaojun Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hydrogel-Based Strategies to Advance Therapies for Chronic Skin Wounds

(2019) Lucília P. da Silva et al.   Annual Review of Biomedical Engineering

Algae-derived β-glucan enhanced gut health and immune responses of weaned pigs experimentally infected with a pathogenic E. coli

(2019) Kwangwook Kim et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Barley β-glucan accelerates wound healing by favoring migration versus proliferation of human dermal fibroblasts

(2019) N.P. Fusté et al.   CARBOHYDRATE POLYMERS

Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials

(2019) Vaclav Vetvicka et al.   MOLECULES

The wound healing effect of four types of beta-glucan

(2019) Gayoung Seo et al.   Applied Biological Chemistry

Glucan and Mannan—Two Peas in a Pod

(2019) Tatiana A. Korolenko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cereal B-Glucans: The Impact of Processing and How It Affects Physiological Responses

(2019) Muriel Henrion et al.   Nutrients

A Concise Review on the Molecular Structure and Function Relationship of β-Glucan

(2019) Bin Du et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pure yeast beta-glucan and two types of yeast cell wall extracts enhance cell migration in porcine intestine model

(2019) Jenna Penney et al.   Journal of Functional Foods

Negative Effects of a High-Fat Diet on Intestinal Permeability: A Review

(2019) Michael W Rohr et al.   Advances in Nutrition

Dietary intervention using (1,3)/(1,6)-β-glucan, a fungus-derived soluble prebiotic ameliorates high-fat diet-induced metabolic distress and alters beneficially the gut microbiota in mice model

(2019) Karthika Muthuramalingam et al.   EUROPEAN JOURNAL OF NUTRITION

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Agaricus brasiliensis KA21 May Prevent Diet-Induced Nash Through Its Antioxidant, Anti-Inflammatory, and Anti-Fibrotic Activities in the Liver

(2019) Anna Nakamura et al.   Foods

Viscosity of β-glucan from oat products at the intestinal phase of the gastrointestinal model

(2019) Noora Mäkelä et al.   FOOD HYDROCOLLOIDS

Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice

(2018) Jostein Grip et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

β-1,3/1,4-Glucan Lichenan from Cetraria islandica (L.) ACH. induces cellular differentiation of human keratinocytes

(2018) Dominika M. Zacharski et al.   FITOTERAPIA

Accelerated Wound Healing on the Skin Using a Film Dressing with β-Glucan Paramylon

(2018) KOSUKE YASUDA et al.   IN VIVO

Effects of functional β-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells

(2018) Yan Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

β-Glucans: Multi-Functional Modulator of Wound Healing

(2018) Juraj Majtan et al.   MOLECULES

Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice

(2018) Junki Miyamoto et al.   PLoS One

β-glucan Salecan Improves Exercise Performance and Displays Anti-Fatigue Effects through Regulating Energy Metabolism and Oxidative Stress in Mice

(2018) Xi Xu et al.   Nutrients

Direct comparison of β-glucan content in wild and cultivated barley

(2018) Mutthanthirige Don Lalith Chandana Nishantha et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

A clinical observation evaluation of bioactive soluble beta-glucan gel compared with standard care

(2018) Sharon D. Hunt   Journal of Wound Care

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

(2018) Vishal Singh et al.   CELL

Agaricus bisporus supplementation reduces high-fat diet-induced body weight gain and fatty liver development

(2018) María Iñiguez et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Creation of Straight-Chain Cationic Polysaccharide-Based Bile Salt Sequestrants Made from Euglenoid β-1,3-Glucan as Potential Antidiabetic Agents

(2018) Motonari Shibakami et al.   PHARMACEUTICAL RESEARCH

Anti-fibrotic activity of Euglena gracilis and paramylon in a mouse model of non-alcoholic steatohepatitis

(2018) Ayaka Nakashima et al.   Food Science & Nutrition

Alterations in gut microbiota composition and metabolic parameters after dietary intervention with barley beta glucans in patients with high risk for metabolic syndrome development

(2018) Ana Velikonja et al.   ANAEROBE

Sprayable Carbopol hydrogel with soluble beta-1,3/1,6-glucan as an active ingredient for wound healing – Development and in-vivo evaluation

(2017) Jostein Grip et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Screening of beta-glucan contents in commercially cultivated and wild growing mushrooms

(2017) Miriam Sari et al.   FOOD CHEMISTRY

A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn’s Disease and Control Subjects

(2017) John-Peter Ganda Mall et al.   INFLAMMATORY BOWEL DISEASES

Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future

(2017) Khawaja Muhammad Bashir et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut Fermentation of Dietary Fibres: Physico-Chemistry of Plant Cell Walls and Implications for Health

(2017) Barbara Williams et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of processing on the beta-glucan physicochemical properties in barley and semolina pasta

(2017) Rosanna De Paula et al.   JOURNAL OF CEREAL SCIENCE

Extraction and Isolation of β-Glucan from Grain Sources-A Review

(2017) Gunjan Maheshwari et al.   JOURNAL OF FOOD SCIENCE

Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats

(2017) Qi Sun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Molecular Weight, Solubility and Viscosity of β-Glucan Preparations from Barley Pearling Byproducts

(2017) Young-Tack Lee et al.   Sains Malaysiana

Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet

(2017) Jie Xu et al.   Nutrients

Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms

(2017) Ping Geng et al.   Biomed Research International

Oral Supplementation with Baker's Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise

(2017) Brian K. McFarlin et al.   Frontiers in Physiology

Toll-Like Receptor Function in Acute Wounds

(2017) Lin Chen et al.   Advances in Wound Care

Characterization of cereal β-glucan extracts from oat and barley and quantification of proteinaceous matter

(2017) Claudia Zielke et al.   PLoS One

β-Glucan content, viscosity, and solubility of Canadian grown oat as influenced by cultivar and growing location

(2016) Mariana Perez Herrera et al.   CANADIAN JOURNAL OF PLANT SCIENCE

Beta-glucan contamination of pharmaceutical products: How much should we accept?

(2016) Claire Barton et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Heat treatment of curdlan enhances the enzymatic production of biologically active β-(1,3)-glucan oligosaccharides

(2016) Yuya Kumagai et al.   CARBOHYDRATE POLYMERS

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Effects of beta-glucans ingestion (Saccharomyces cerevisiae) on metabolism of rats receiving high-fat diet

(2016) T. V. de Araújo et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Nonalcoholic fatty liver disease and hepatocellular carcinoma

(2016) Heinz Zoller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Particulate β-glucans synergistically activate TLR4 and Dectin-1 in human dendritic cells

(2016) Neha M. Sahasrabudhe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cyclic β-(1→3) (1→6) glucan/carrageenan hydrogels for wound healing applications

(2016) Anju V. Nair et al.   RSC Advances

High Molecular Weight Barley β-Glucan Alters Gut Microbiota Toward Reduced Cardiovascular Disease Risk

(2016) Yanan Wang et al.   Frontiers in Microbiology

Lack of soluble fiber drives diet-induced adiposity in mice

(2015) Benoit Chassaing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Modification of the degree of branching of a beta-(1,3)-glucan affects aggregation behavior and activity in an oxidative burst assay

(2015) Andrew S. Magee et al.   BIOPOLYMERS

Construction of selenium nanoparticles/β-glucan composites for enhancement of the antitumor activity

(2015) Xuewei Jia et al.   CARBOHYDRATE POLYMERS

Nutrition to Support Recovery from Endurance Exercise

(2015) Daniel R. Moore   Current Sports Medicine Reports

Molecular Interactions of β-(1→3)-Glucans with Their Receptors

(2015) Laurent Legentil et al.   MOLECULES

Protective effect of β-glucan on acute lung injury induced bylipopolysaccharide in rats

(2015) Meryem IRAZ et al.   Turkish Journal Of Medical Sciences

Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice

(2015) Shiho Aoki et al.   Scientific Reports

Vocal Fold Augmentation with Beta Glucan Hydrogel Cross-Linked byγIrradiation for Enhanced Duration of Effect:In VivoAnimal Study

(2015) Youn-Mook Lim et al.   Biomed Research International

Dectin-1 activation induces proliferation and migration of human keratinocytes enhancing wound re-epithelialization

(2014) Linda M van den Berg et al.   CELLULAR IMMUNOLOGY

β-glucan reduces exercise-induced stress through downregulation of c-Fos and c-Jun expression in the brains of exhausted rats

(2014) HEEOK HONG et al.   Molecular Medicine Reports

Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan

(2014) Heike Stier et al.   Nutrition Journal

Beta-Glucan-Rich Extract fromPleurotus sajor-caju(Fr.) Singer Prevents Obesity and Oxidative Stress in C57BL/6J Mice Fed on a High-Fat Diet

(2013) G. Kanagasabapathy et al.   Evidence-based Complementary and Alternative Medicine

β-glucan enriched bath directly stimulates the wound healing process in common carp (Cyprinus carpio L.)

(2013) D.A. Przybylska-Diaz et al.   FISH & SHELLFISH IMMUNOLOGY

Immunostimulatory properties and antitumor activities of glucans

(2013) LUCA VANNUCCI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Impact of the Molecular Weight, Viscosity, and Solubility of β-Glucan on in Vitro Oat Starch Digestibility

(2013) Hyun Jung Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

High Dietary Glycemic Index and Low Fiber Content Are Associated with Metabolic Syndrome in Patients with Type 2 Diabetes

(2013) Flávia M. Silva et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects

(2013) Greta Jakobsdottir et al.   PLoS One

Oat β-glucan inhibits lipopolysaccharide-induced nonalcoholic steatohepatitis in mice

(2013) Shuiping You et al.   Food & Function

Antitumor activity of the β-glucan paramylon from Euglena against preneoplastic colonic aberrant crypt foci in mice

(2013) Toshiaki Watanabe et al.   Food & Function

Macrophage stimulating agent soluble yeast β-1,3/1,6-glucan as a topical treatment of diabetic foot and leg ulcers: A randomized, double blind, placebo-controlled phase II study

(2013) Svetlana N Zykova et al.   Journal of Diabetes Investigation

Oat beta-glucan ameliorates insulin resistance in mice fed on high-fat and high-fructose diet

(2013) Jie Zheng et al.   Food & Nutrition Research

Effects of oat β-glucan on endurance exercise and its anti-fatigue properties in trained rats

(2012) Chao Xu et al.   CARBOHYDRATE POLYMERS

Consumption of a high β-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat

(2012) David A. Brockman et al.   EUROPEAN JOURNAL OF NUTRITION

Protective Effects of Beta Glucan and Gliclazide on Brain Tissue and Sciatic Nerve of Diabetic Rats Induced by Streptozosin

(2012) Harun Alp et al.   Experimental Diabetes Research

Correlation of branching structure of mushroom β-glucan with its physiological activities

(2012) In Young Bae et al.   FOOD RESEARCH INTERNATIONAL

Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling

(2012) Jianping Fang et al.   GLYCOCONJUGATE JOURNAL

Evaluation of Electrospun (1,3)-(1,6)-β-D-Glucans/Biodegradable Polymer as Artificial Skin for Full-Thickness Wound Healing

(2012) Hye-Lee Kim et al.   TISSUE ENGINEERING PART A

Exercise-Induced Immunodepression in Endurance Athletes and Nutritional Intervention with Carbohydrate, Protein and Fat — What Is Possible, What Is Not?

(2012) Wolfgang Gunzer et al.   Nutrients

Water-soluble polysaccharides from the brown alga Eisenia bicyclis: Structural characteristics and antitumor activity

(2012) Svetlana Ermakova et al.   Algal Research-Biomass Biofuels and Bioproducts

A Novel Soluble Beta-Glucan Salecan Protects against Acute Alcohol-Induced Hepatotoxicity in Mice

(2011) Peng CHEN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived  -glucans

(2011) C. Qi et al.   BLOOD

Beta Glucan: A Valuable Functional Ingredient in Foods

(2011) Asif Ahmad et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Hypoglycaemic effects and inhibitory effect on intestinal disaccharidases of oat beta-glucan in streptozotocin-induced diabetic mice

(2011) Jilin Dong et al.   FOOD CHEMISTRY

Effect of a low molecular weight, high-purity β-glucan onin vitrodigestion and glycemic response

(2011) Pariyarath Sangeetha Thondre et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Natural glycans and glycoconjugates as immunomodulating agents

(2011) Ilona Chlubnová et al.   NATURAL PRODUCT REPORTS

Chemistry, physico-chemistry and applications linked to biological activities of β-glucans

(2011) Laura Barsanti et al.   NATURAL PRODUCT REPORTS

Stimulatory Effect of β-glucans on Immune Cells

(2011) Hyung Sook Kim et al.   Immune Network

The role of molecular weight and viscosity of oat β-glucan in hypocholesterolemic effect

(2010) Jiezhong Chen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits

(2010) Ahmed Bilal Waqar et al.   ATHEROSCLEROSIS

The biological activities of (1,3)-(1,6)-β-d-glucan and porous electrospun PLGA membranes containing β-glucan in human dermal fibroblasts and adipose tissue-derived stem cells

(2010) Yeon I Woo et al.   Biomedical Materials

Evaluation of water soluble β-d-glucan from Auricularia auricular-judae as potential anti-tumor agent

(2010) Zhaocheng Ma et al.   CARBOHYDRATE POLYMERS

Immunopotentiation and anti-tumor activity of carboxymethylated-sulfated β-(1→3)-d-glucan from Poria cocos

(2010) Xiaoyu Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

High-carbohydrate, High-fat Diet–induced Metabolic Syndrome and Cardiovascular Remodeling in Rats

(2010) Sunil K. Panchal et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

Effect of oat bran on time to exhaustion, glycogen content and serum cytokine profile following exhaustive exercise

(2010) Felipe F Donatto et al.   Journal of the International Society of Sports Nutrition

Consumption of barley β-glucan ameliorates fatty liver and insulin resistance in mice fed a high-fat diet

(2010) Joo Sun Choi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of Dietary Fiber and Its Components on Metabolic Health

(2010) James M. Lattimer et al.   Nutrients

Extraction of β-Glucan from Oat Bran in Laboratory Scale

(2009) Tina Immerstrand et al.   CEREAL CHEMISTRY

Glucose and insulin responses to whole grain breakfasts varying in soluble fiber, β-glucan

(2009) Hyunsook Kim et al.   EUROPEAN JOURNAL OF NUTRITION

β-glucan recognition by the innate immune system

(2009) Helen S. Goodridge et al.   IMMUNOLOGICAL REVIEWS

Physicochemical Properties of β-Glucan in Differently Processed Oat Foods Influence Glycemic Response

(2009) Alejandra Regand et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Wound repair at a glance

(2009) T. J. Shaw et al.   JOURNAL OF CELL SCIENCE

The effects of β-glucan on human immune and cancer cells

(2009) Godfrey Chan et al.   Journal of Hematology & Oncology

Health benefits of dietary fiber

(2009) James W Anderson et al.   NUTRITION REVIEWS

Glucans as Biological Response Modifiers

(2009) M. Novak et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Effects of medicinal mushroom (Sparassis crispa) on wound healing in streptozotocin-induced diabetic rats

(2008) A.-Hon Kwon et al.   AMERICAN JOURNAL OF SURGERY

Three exopolysaccharides of the β-(1→6)- d -glucan type and a β-(1→3;1→6)- d -glucan produced by strains of Botryosphaeria rhodina isolated from rotting tropical fruit

(2008) Ana Flora D. Vasconcelos et al.   CARBOHYDRATE RESEARCH

Dietary Fiber in the Prevention and Treatment of Metabolic Syndrome: A Review

(2008) Amaya Aleixandre et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Isolation ofβ-glucan from the cell wall ofSaccharomyces cerevisiae

(2008) Hojjatollah Shokri et al.   NATURAL PRODUCT RESEARCH

Viscosity of beta-glucan in oat products

(2005) H. ANTTILA et al.   AGRICULTURAL AND FOOD SCIENCE