Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy
Authors
Keywords
-
Journal
PERIODONTOLOGY 2000
Volume 84, Issue 1, Pages 14-34
Publisher
Wiley
Online
2020-08-26
DOI
10.1111/prd.12331
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
- (2018) Ioannis Mitroulis et al. CELL
- BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
- (2018) Rob J.W. Arts et al. Cell Host & Microbe
- New Analogs of the Complement C3 Inhibitor Compstatin with Increased Solubility and Improved Pharmacokinetic Profile
- (2018) Nadja Berger et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tissue-Specific Immunity at the Oral Mucosal Barrier
- (2018) Niki M. Moutsopoulos et al. TRENDS IN IMMUNOLOGY
- Host defense against oral microbiota by bone-damaging T cells
- (2018) Masayuki Tsukasaki et al. Nature Communications
- Prevalence of gingivitis and calculus in 12-year-old Puerto Ricans: a cross-sectional study
- (2018) Augusto R. Elias-Boneta et al. BMC Oral Health
- Safety profile after prolonged C3 inhibition
- (2018) Edimara S. Reis et al. CLINICAL IMMUNOLOGY
- DEL-1 promotes macrophage efferocytosis and clearance of inflammation
- (2018) Ioannis Kourtzelis et al. NATURE IMMUNOLOGY
- The oral microbiota: dynamic communities and host interactions
- (2018) Richard J. Lamont et al. NATURE REVIEWS MICROBIOLOGY
- A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans
- (2018) Nicolas Dutzan et al. Science Translational Medicine
- Immunometabolic Crosstalk: An Ancestral Principle of Trained Immunity?
- (2018) Sider Penkov et al. TRENDS IN IMMUNOLOGY
- Endothelial transplantation rejuvenates aged hematopoietic stem cell function
- (2017) Michael G. Poulos et al. JOURNAL OF CLINICAL INVESTIGATION
- Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche
- (2017) Ioannis Mitroulis et al. JOURNAL OF CLINICAL INVESTIGATION
- Milk fat globule epidermal growth factor 8 inhibits periodontitis in non-human primates and its gingival crevicular fluid levels can differentiate periodontal health from disease in humans
- (2017) Tetsuhiro Kajikawa et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Global epidemiology of dental caries and severe periodontitis - a comprehensive review
- (2017) Jo E. Frencken et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Natural history of periodontitis: Disease progression and tooth loss over 40 years
- (2017) Christoph A. Ramseier et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Role of microbial communities in the pathogenesis of periodontal diseases and caries
- (2017) Alex Mira et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Gingivitis and lifestyle influences on high-sensitivity C-reactive protein and interleukin 6 in adolescents
- (2017) Vinay Pitchika et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Differential Expression and Roles of Secreted Frizzled-Related Protein 5 and the Wingless Homolog Wnt5a in Periodontitis
- (2017) T. Maekawa et al. JOURNAL OF DENTAL RESEARCH
- From leukocyte recruitment to resolution of inflammation: the cardinal role of integrins
- (2017) Ioannis Kourtzelis et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Denosumab-related osteonecrosis of the jaw: A retrospective study
- (2017) Claire Egloff-Juras et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Impact of periodontal disease on quality of life: a systematic review
- (2017) M. C. Ferreira et al. JOURNAL OF PERIODONTAL RESEARCH
- Pro-resolving mediators in the regulation of periodontal disease
- (2017) Thomas E. Van Dyke MOLECULAR ASPECTS OF MEDICINE
- The renaissance of complement therapeutics
- (2017) Daniel Ricklin et al. Nature Reviews Nephrology
- Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
- (2017) Niki M. Moutsopoulos et al. NEW ENGLAND JOURNAL OF MEDICINE
- Host modulation: controlling the inflammation to control the infection
- (2017) P. Mark Bartold et al. PERIODONTOLOGY 2000
- Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later
- (2017) George Hajishengallis et al. PERIODONTOLOGY 2000
- Porphyromonas gingivalis Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88
- (2017) Hasnaa Makkawi et al. Frontiers in Cellular and Infection Microbiology
- Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates
- (2017) Tetsuhiro Kajikawa et al. Molecular Therapy-Methods & Clinical Development
- Rapamycin treatment attenuates age-associated periodontitis in mice
- (2017) Jonathan Y. An et al. GeroScience
- Oral administration of Lactobacillus gasseri SBT2055 is effective in preventing Porphyromonas gingivalis-accelerated periodontal disease
- (2017) R. Kobayashi et al. Scientific Reports
- Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient MiceSignificance
- (2016) Amanda C. Foks et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Omega-3 fatty acids as an adjunct for periodontal therapy—a review
- (2016) B. Chee et al. Clinical Oral Investigations
- Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease
- (2016) Steven Offenbacher et al. HUMAN MOLECULAR GENETICS
- Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3
- (2016) Tomoki Maekawa et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Clinical efficacy of probiotics as an adjunctive therapy to non-surgical periodontal treatment of chronic periodontitis: a systematic review and meta-analysis
- (2016) Rodrigo Martin-Cabezas et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Microenvironmental Views on Mesenchymal Stem Cell Differentiation in Aging
- (2016) B.D. Sui et al. JOURNAL OF DENTAL RESEARCH
- Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis
- (2016) Chun-Teh Lee et al. JOURNAL OF IMMUNOLOGY
- Characterization of the human immune cell network at the gingival barrier
- (2016) N Dutzan et al. Mucosal Immunology
- Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
- (2016) David R Withers et al. NATURE MEDICINE
- Complement in disease: a defence system turning offensive
- (2016) Daniel Ricklin et al. Nature Reviews Nephrology
- From restoration to regeneration: periodontal aging and opportunities for therapeutic intervention
- (2016) Lan Huang et al. PERIODONTOLOGY 2000
- Aging, inflammation, immunity and periodontal disease
- (2016) Jeffrey L. Ebersole et al. PERIODONTOLOGY 2000
- Trained immunity: A program of innate immune memory in health and disease
- (2016) M. G. Netea et al. SCIENCE
- Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity
- (2016) Yanxia Guo et al. Cell Reports
- A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis
- (2016) Neil M O’Brien-Simpson et al. npj Vaccines
- Comparative metagenomics reveals taxonomically idiosyncratic yet functionally congruent communities in periodontitis
- (2016) Shareef M. Dabdoub et al. Scientific Reports
- Age-related decline in the matrix contents and functional properties of human periodontal ligament stem cell sheets
- (2015) Rui-Xin Wu et al. Acta Biomaterialia
- Transcellular biosynthesis of eicosanoid lipid mediators
- (2015) Valérie Capra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Intracellular signalling during neutrophil recruitment
- (2015) Attila Mócsai et al. CARDIOVASCULAR RESEARCH
- Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells
- (2015) Fabio R. Santori et al. Cell Metabolism
- Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention
- (2015) Dimitrios C. Mastellos et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Host response mechanisms in periodontal diseases
- (2015) Nora SILVA et al. Journal of Applied Oral Science
- Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury
- (2015) Kazuto Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-B lymphocyte immunotherapy is associated with improvement of periodontal status in subjects with rheumatoid arthritis
- (2015) Juliette Coat et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- The B Cell–Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell–Dependent Bone Loss in Experimental Murine Periodontitis
- (2015) Toshiharu Abe et al. JOURNAL OF IMMUNOLOGY
- Role of the endothelial surface layer in neutrophil recruitment
- (2015) A. Marki et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Immune system transcriptome in gingival tissues of young nonhuman primates
- (2015) O. A. Gonzalez et al. JOURNAL OF PERIODONTAL RESEARCH
- Epigenetics and Its Role in Periodontal Diseases: A State-of-the-Art Review
- (2015) Lena Larsson et al. JOURNAL OF PERIODONTOLOGY
- Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012
- (2015) Paul I. Eke et al. JOURNAL OF PERIODONTOLOGY
- Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa
- (2015) J.L. Ebersole et al. Molecular Oral Microbiology
- Peroxisome proliferator-activated receptor δ inhibitsPorphyromonas gingivalislipopolysaccharide-induced activation of matrix metalloproteinase-2 by downregulating NADPH oxidase 4 in human gingival fibroblasts
- (2015) T. Yoo et al. Molecular Oral Microbiology
- Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention
- (2015) D.C. Mastellos et al. Molecular Oral Microbiology
- PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines
- (2015) Y-S Yoon et al. Mucosal Immunology
- Modulation of the host response by probioticLactobacillus brevisCD2 in experimental gingivitis
- (2015) J-K Lee et al. ORAL DISEASES
- Basic biology and role of interleukin-17 in immunity and inflammation
- (2015) Camille Zenobia et al. PERIODONTOLOGY 2000
- DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates
- (2015) Jieun Shin et al. Science Translational Medicine
- HSC Aging and Senescent Immune Remodeling
- (2015) Michael D. Denkinger et al. TRENDS IN IMMUNOLOGY
- Polymicrobial synergy and dysbiosis in inflammatory disease
- (2015) Richard J. Lamont et al. TRENDS IN MOLECULAR MEDICINE
- Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway
- (2015) Tomoki Maekawa et al. Nature Communications
- Functional signatures of oral dysbiosis during periodontitis progression revealed by microbial metatranscriptome analysis
- (2015) Susan Yost et al. Genome Medicine
- Subgingival microbiota in health compared to periodontitis and the influence of smoking
- (2015) Anny J. Camelo-Castillo et al. Frontiers in Microbiology
- How Neutrophils Shape Adaptive Immune Responses
- (2015) Pieter H. C. Leliefeld et al. Frontiers in Immunology
- Prospects for treatment of Porphyromonas gingivalis-mediated disease – immune-based therapy
- (2015) Eric C. Reynolds et al. Journal of Oral Microbiology
- Social networking of human neutrophils within the immune system
- (2014) P. Scapini et al. BLOOD
- Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis
- (2014) Tomoki Maekawa et al. Cell Host & Microbe
- Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis
- (2014) Ana E Duran-Pinedo et al. ISME Journal
- Smoking decreases structural and functional resilience in the subgingival ecosystem
- (2014) Vinayak Joshi et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Global Burden of Severe Periodontitis in 1990-2010
- (2014) N.J. Kassebaum et al. JOURNAL OF DENTAL RESEARCH
- Chronic Periodontitis Genome-wide Association Studies
- (2014) K. Rhodin et al. JOURNAL OF DENTAL RESEARCH
- Docosahexaenoic Acid and Periodontitis in Adults
- (2014) A.Z. Naqvi et al. JOURNAL OF DENTAL RESEARCH
- Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis
- (2014) T.E. Van Dyke et al. JOURNAL OF DENTAL RESEARCH
- C1q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition
- (2014) H. Paidassi et al. JOURNAL OF IMMUNOLOGY
- Regulation of Osteoclast Homeostasis and Inflammatory Bone Loss by MFG-E8
- (2014) T. Abe et al. JOURNAL OF IMMUNOLOGY
- Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis
- (2014) T. Maekawa et al. JOURNAL OF IMMUNOLOGY
- Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis
- (2014) G. Hajishengallis et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Topical treatment with probioticLactobacillus brevisCD2 inhibits experimental periodontal inflammation and bone loss
- (2014) T. Maekawa et al. JOURNAL OF PERIODONTAL RESEARCH
- Cellular composition of long-standing gingivitis and periodontitis lesions
- (2014) S. Thorbert-Mros et al. JOURNAL OF PERIODONTAL RESEARCH
- The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis
- (2014) Ronald S. Flannagan et al. MOLECULAR BIOLOGY OF THE CELL
- The inflammophilic character of the periodontitis-associated microbiota
- (2014) G. Hajishengallis Molecular Oral Microbiology
- Pro-resolving lipid mediators are leads for resolution physiology
- (2014) Charles N. Serhan NATURE
- Hematopoietic stem cell niche maintenance during homeostasis and regeneration
- (2014) Avital Mendelson et al. NATURE MEDICINE
- The BAFF/APRIL system in SLE pathogenesis
- (2014) Fabien B. Vincent et al. Nature Reviews Rheumatology
- Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss
- (2014) N. M. Moutsopoulos et al. Science Translational Medicine
- Age associated communication between cells and matrix: a potential impact on stem cell-based tissue regeneration strategies
- (2014) Kevin Lynch et al. Organogenesis
- Time to take periodontitis seriously
- (2014) I. L. C. Chapple BMJ-British Medical Journal
- Common Risk Factors in the Management of Periodontal and Associated Systemic Diseases: The Dental Setting and Interprofessional Collaboration
- (2014) Robert J. Genco et al. Journal of Evidence-Based Dental Practice
- Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases
- (2013) Matthew Spite et al. Cell Metabolism
- New biologic therapy for systemic lupus erythematosus
- (2013) Hui Jen Ding et al. CURRENT OPINION IN PHARMACOLOGY
- Resolution of inflammation: an integrated view
- (2013) Almudena Ortega-Gómez et al. EMBO Molecular Medicine
- Porphyromonas gingivalis Infection-Associated Periodontal Bone Resorption Is Dependent on Receptor Activator of NF-κB Ligand
- (2013) Xiaozhe Han et al. INFECTION AND IMMUNITY
- Impact of periodontal disease and periodontal therapy on oral health-related quality of life
- (2013) Fabian Brauchle et al. INTERNATIONAL DENTAL JOURNAL
- The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation
- (2013) Loreto Abusleme et al. ISME Journal
- Diverse novel functions of neutrophils in immunity, inflammation, and beyond
- (2013) Attila Mócsai JOURNAL OF EXPERIMENTAL MEDICINE
- Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms
- (2013) D. Ricklin et al. JOURNAL OF IMMUNOLOGY
- Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned concepts
- (2013) P. Mark Bartold et al. PERIODONTOLOGY 2000
- Modifiable risk factors in periodontitis: at the intersection of aging and disease
- (2013) Mark A. Reynolds PERIODONTOLOGY 2000
- Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes
- (2013) A. J. Glowacki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities
- (2013) I. Tabas et al. SCIENCE
- Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin
- (2013) Ioannis Mitroulis et al. THROMBOSIS AND HAEMOSTASIS
- Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response
- (2013) George Hajishengallis TRENDS IN IMMUNOLOGY
- New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties
- (2012) Hongchang Qu et al. IMMUNOBIOLOGY
- Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity
- (2012) Yoko Kidani et al. IMMUNOLOGICAL REVIEWS
- Complement C3a-Induced IL-17 Plays a Critical Role in an IgE-Mediated Late-Phase Asthmatic Response and Airway Hyperresponsiveness via Neutrophilic Inflammation in Mice
- (2012) N. Mizutani et al. JOURNAL OF IMMUNOLOGY
- Local Complement-Targeted Intervention in Periodontitis: Proof-of-Concept Using a C5a Receptor (CD88) Antagonist
- (2012) T. Abe et al. JOURNAL OF IMMUNOLOGY
- Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects
- (2012) MiJung Kim et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss
- (2012) Mehmet A Eskan et al. NATURE IMMUNOLOGY
- Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
- (2012) Kazuhiro Maeda et al. NATURE MEDICINE
- Targeting IL-17 and TH17 cells in chronic inflammation
- (2012) Pierre Miossec et al. NATURE REVIEWS DRUG DISCOVERY
- The keystone-pathogen hypothesis
- (2012) George Hajishengallis et al. NATURE REVIEWS MICROBIOLOGY
- Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans
- (2012) Rafael Solana et al. SEMINARS IN IMMUNOLOGY
- New insights into osteoclastogenic signaling mechanisms
- (2012) Tomoki Nakashima et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Effect of anti-rheumatic agents on periodontal parameters and biomarkers of inflammation: a systematic review and meta-analysis
- (2012) Ji Young Han et al. Journal of Periodontal and Implant Science
- A Review of α1-Antitrypsin Deficiency
- (2011) James K. Stoller et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Review: milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation
- (2011) Monowar Aziz et al. APOPTOSIS
- Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement
- (2011) George Hajishengallis et al. Cell Host & Microbe
- Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis
- (2011) Markus Bosmann et al. FASEB JOURNAL
- Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways
- (2011) Kodi S. Ravichandran IMMUNITY
- Recombinant human milk fat globule-EGF factor 8 produces dose-dependent benefits in sepsis
- (2011) Kavin G. Shah et al. INTENSIVE CARE MEDICINE
- Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing
- (2011) Ann L Griffen et al. ISME Journal
- Coordinate regulation of neutrophil homeostasis by liver X receptors in mice
- (2011) Cynthia Hong et al. JOURNAL OF CLINICAL INVESTIGATION
- Biological approaches to the development of novel periodontal therapies - Consensus of the Seventh European Workshop on Periodontology
- (2011) Maurizio S. Tonetti et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- The RANKL-OPG system in clinical periodontology
- (2011) Georgios N. Belibasakis et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Effect of non-surgical periodontal therapy on the levels of Th17/Th1/Th2 cytokines and their transcription factors in Chinese chronic periodontitis patients
- (2011) Lu Zhao et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Induction of IL-10-producing CD4+ T-cells in Chronic Periodontitis
- (2011) R. Kobayashi et al. JOURNAL OF DENTAL RESEARCH
- Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration
- (2011) Baoying Liu et al. Journal of Translational Medicine
- Emerging Role of PPAR-β/δin Inflammatory Process Associated to Experimental Periodontitis
- (2011) Rosanna Di Paola et al. MEDIATORS OF INFLAMMATION
- The neutrophil in vascular inflammation
- (2011) Mia Phillipson et al. NATURE MEDICINE
- Recombinant human MFG-E8 attenuates cerebral ischemic injury: Its role in anti-inflammation and anti-apoptosis
- (2011) Cletus Cheyuo et al. NEUROPHARMACOLOGY
- Genetic susceptibility to periodontitis
- (2011) Marja L. Laine et al. PERIODONTOLOGY 2000
- Tobacco Smoke Augments Porphyromonas gingivalis - Streptococcus gordonii Biofilm Formation
- (2011) Juhi Bagaitkar et al. PLoS One
- Denosumab and bisphosphonates: Different mechanisms of action and effects
- (2010) Roland Baron et al. BONE
- Novel Lipid Mediators Promote Resolution of Acute Inflammation
- (2010) Matthew Spite et al. CIRCULATION RESEARCH
- Control of Macrophage Activation and Function by PPARs
- (2010) Ajay Chawla CIRCULATION RESEARCH
- Complement C5a regulates IL-17 by affecting the crosstalk between DC and γδ T cells in CLP-induced sepsis
- (2010) Ruonan Xu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism
- (2010) Franziska Petermann et al. IMMUNITY
- Antibody to Receptor Activator of NF-κB Ligand Ameliorates T Cell-Mediated Periodontal Bone Resorption
- (2010) Xiaoping Lin et al. INFECTION AND IMMUNITY
- The Human Oral Microbiome
- (2010) F. E. Dewhirst et al. JOURNAL OF BACTERIOLOGY
- Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
- (2010) David E. Hughes et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Destructive and Protective Roles of Cytokines in Periodontitis: A Re-appraisal from Host Defense and Tissue Destruction Viewpoints
- (2010) G.P. Garlet JOURNAL OF DENTAL RESEARCH
- The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss
- (2010) S. Liang et al. JOURNAL OF IMMUNOLOGY
- Adjunctive Treatment of Chronic Periodontitis With Daily Dietary Supplementation With Omega-3 Fatty Acids and Low-Dose Aspirin
- (2010) Hesham El-Sharkawy et al. JOURNAL OF PERIODONTOLOGY
- Denosumab
- (2010) Steven C. Pageau mAbs
- Too old to fight? Aging and its toll on innate immunity
- (2010) G. Hajishengallis Molecular Oral Microbiology
- COX-2's new role in inflammation
- (2010) Chu Chen Nature Chemical Biology
- Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
- (2010) Stephane Lajoie et al. NATURE IMMUNOLOGY
- Complement: a key system for immune surveillance and homeostasis
- (2010) Daniel Ricklin et al. NATURE IMMUNOLOGY
- Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures
- (2010) Thomas Beikler et al. PERIODONTOLOGY 2000
- Epidemiologic patterns of chronic and aggressive periodontitis
- (2010) Ryan T. Demmer et al. PERIODONTOLOGY 2000
- Clinical studies on the management of periodontal diseases utilizing subantimicrobial dose doxycycline (SDD)
- (2010) Jack Caton et al. PHARMACOLOGICAL RESEARCH
- Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity
- (2010) N. Ouchi et al. SCIENCE
- Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells
- (2010) J. J. O'Shea et al. SCIENCE
- WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis
- (2010) Enrico Briguglio et al. PPAR Research
- Evidence for a cross-talk between human neutrophils and Th17 cells
- (2009) M. Pelletier et al. BLOOD
- Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR
- (2009) Noelia A-Gonzalez et al. IMMUNITY
- A New Inflammatory Cytokine on the Block: Re-thinking Periodontal Disease and the Th1/Th2 Paradigm in the Context of Th17 Cells and IL-17
- (2009) S.L. Gaffen et al. JOURNAL OF DENTAL RESEARCH
- Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine
- (2009) G.T.-J. Huang et al. JOURNAL OF DENTAL RESEARCH
- Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
- (2009) Matthew Spite et al. NATURE
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- Novel aspects in the regulation of the leukocyte adhesion cascade
- (2009) Emmanouil Chavakis et al. THROMBOSIS AND HAEMOSTASIS
- Loss of Proliferation and Differentiation Capacity of Aged Human Periodontal Ligament Stem Cells and Rejuvenation by Exposure to the Young Extrinsic Environment
- (2009) Wei Zheng et al. TISSUE ENGINEERING PART A
- Aging of hematopoietic stem cells is regulated by the stem cell niche
- (2008) Wolfgang Wagner et al. EXPERIMENTAL GERONTOLOGY
- Innate immunity and aging
- (2008) Christian R. Gomez et al. EXPERIMENTAL GERONTOLOGY
- Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease
- (2008) P. Bovolenta et al. JOURNAL OF CELL SCIENCE
- Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
- (2008) Joshua D. Milner et al. NATURE
- Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment
- (2008) E. Y. Choi et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started