The inflammophilic character of the periodontitis-associated microbiota

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

(2014) Tomoki Maekawa et al.   Cell Host & Microbe

Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis

(2014) Ana E Duran-Pinedo et al.   ISME Journal

Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis

(2014) T. Maekawa et al.   JOURNAL OF IMMUNOLOGY

Topical treatment with probioticLactobacillus brevisCD2 inhibits experimental periodontal inflammation and bone loss

(2014) T. Maekawa et al.   JOURNAL OF PERIODONTAL RESEARCH

Transcriptional profiling of human gingival fibroblasts in response to multi-speciesin vitrosubgingival biofilms

(2014) G.N. Belibasakis et al.   Molecular Oral Microbiology

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

(2014) N. M. Moutsopoulos et al.   Science Translational Medicine

Metatranscriptomics of the Human Oral Microbiome during Health and Disease

(2014) P. Jorth et al.   mBio

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses

(2014) Kheng H. Tan et al.   PLoS Pathogens

Induction of Bone Loss by Pathobiont-Mediated Nod1 Signaling in the Oral Cavity

(2013) Yizu Jiao et al.   Cell Host & Microbe

Breaking bad: Manipulation of the host response byPorphyromonas gingivalis

(2013) George Hajishengallis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exploring the genetic basis of chronic periodontitis: a genome-wide association study

(2013) K. Divaris et al.   HUMAN MOLECULAR GENETICS

Porphyromonas gingivalis Lipid A Phosphatase Activity Is Critical for Colonization and Increasing the Commensal Load in the Rabbit Ligature Model

(2013) Camille Zenobia et al.   INFECTION AND IMMUNITY

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation

(2013) Loreto Abusleme et al.   ISME Journal

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response

(2013) George Hajishengallis   TRENDS IN IMMUNOLOGY

The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65

(2013) Hiroki Takeuchi et al.   PLoS Pathogens

Epigenetic biomarkers: a step forward for understanding periodontitis

(2013) Anders M. Lindroth et al.   Journal of Periodontal and Implant Science

Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen

(2012) Nagihan Bostanci et al.   FEMS MICROBIOLOGY LETTERS

Fusobacterium nucleatum and Tannerella forsythia Induce Synergistic Alveolar Bone Loss in a Mouse Periodontitis Model

(2012) Rajendra P. Settem et al.   INFECTION AND IMMUNITY

Structure of Factor H-binding Protein B (FhbB) of the Periopathogen,Treponema denticola

(2012) Daniel P. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyromonas gingivalis as a Potential Community Activist for Disease

(2012) R.P. Darveau et al.   JOURNAL OF DENTAL RESEARCH

Local Complement-Targeted Intervention in Periodontitis: Proof-of-Concept Using a C5a Receptor (CD88) Antagonist

(2012) T. Abe et al.   JOURNAL OF IMMUNOLOGY

A Metalloproteinase Karilysin Present in the Majority of Tannerella forsythia Isolates Inhibits All Pathways of the Complement System

(2012) M. Jusko et al.   JOURNAL OF IMMUNOLOGY

Impact of Periodontal Therapy on the Subgingival Microbiota of Severe Periodontitis: Comparison Between Good Responders and Individuals With Refractory Periodontitis Using the Human Oral Microbe Identification Microarray

(2012) Ana Paula V. Colombo et al.   JOURNAL OF PERIODONTOLOGY

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

(2012) Mehmet A Eskan et al.   NATURE IMMUNOLOGY

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

The Relationship of the Oral Microbiotia to Periodontal Health and Disease

(2011) Michael A. Curtis et al.   Cell Host & Microbe

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing

(2011) Ann L Griffen et al.   ISME Journal

Effect of periodontal treatment on receptor activator of NF-κB ligand and osteoprotegerin levels and relative ratio in gingival crevicular fluid

(2011) Nagihan Bostanci et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Synergistic virulence of Porphyromonas gingivalis and Treponema denticola in a murine periodontitis model

(2011) R.K-H. Orth et al.   Molecular Oral Microbiology

Genetic susceptibility to periodontitis

(2011) Marja L. Laine et al.   PERIODONTOLOGY 2000

CORE: A Phylogenetically-Curated 16S rDNA Database of the Core Oral Microbiome

(2011) Ann L. Griffen et al.   PLoS One

Signaling mechanisms in the restoration of impaired immune function due to diet-induced obesity

(2011) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolite Cross-Feeding Enhances Virulence in a Model Polymicrobial Infection

(2011) Matthew M. Ramsey et al.   PLoS Pathogens

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

The use of rodent models to investigate host-bacteria interactions related to periodontal diseases

(2010) Dana T. Graves et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss

(2010) S. Liang et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitis

(2010) Ayala Stabholz et al.   PERIODONTOLOGY 2000

Microbial Hijacking of Complement-Toll-Like Receptor Crosstalk

(2010) M. Wang et al.   Science Signaling

Mouse model of experimental periodontitis induced byPorphyromonas gingivalis/Fusobacterium nucleatuminfection: bone loss and host response

(2009) David Polak et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

(2009) Jennifer L. Krauss et al.   PERIODONTOLOGY 2000

Corruption of Innate Immunity by Bacterial Proteases

(2008) Jan Potempa et al.   Journal of Innate Immunity

Cytokines That Promote Periodontal Tissue Destruction

(2008) Dana Graves   JOURNAL OF PERIODONTOLOGY

Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing

(2008) Vishwanath Venketaraman et al.   MICROBIAL PATHOGENESIS

The chronicles of Porphyromonas gingivalis: the microbium, the human oral epithelium and their interplay

(2008) O. Yilmaz   MICROBIOLOGY-SGM