Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins

Assembly and substrate recognition of curli biogenesis system

(2020) Zhaofeng Yan et al.   Nature Communications

Nucleolar Organization and Functions in Health and Disease

(2020) Ursula Stochaj et al.   Cells

Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila

(2020) Ruben Hervas et al.   SCIENCE

Spot the Difference: Function versus Toxicity in Amyloid Fibrils

(2020) Sabine M. Ulamec et al.   TRENDS IN BIOCHEMICAL SCIENCES

The mechanism of Hsp90-induced oligomerizaton of Tau

(2020) S. Weickert et al.   Science Advances

Current understanding of metal ions in the pathogenesis of Alzheimer’s disease

(2020) Lu Wang et al.   Translational Neurodegeneration

Do Post-Translational Modifications Influence Protein Aggregation in Neurodegenerative Diseases: A Systematic Review

(2020) Larissa-Nele Schaffert et al.   Brain Sciences

Hydroxytyrosol Inhibits Protein Oligomerization and Amyloid Aggregation in Human Insulin

(2020) Ivana Sirangelo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

(2020) Fabian den Brave et al.   Cell Reports

Allosteric disulfides: Sophisticated molecular structures enabling flexible protein regulation

(2019) Joyce Chiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc binding regulates amyloid-like aggregation of GAPR-1

(2019) Jie Sheng et al.   BIOSCIENCE REPORTS

Ca(II) and Zn(II) Cooperate To Modulate the Structure and Self-Assembly of S100A12

(2019) Qian Wang et al.   BIOCHEMISTRY

Phase Separation in Regulation of Aggrephagy

(2019) Daxiao Sun et al.   JOURNAL OF MOLECULAR BIOLOGY

Liquid–Liquid Phase Separation in Disease

(2019) Simon Alberti et al.   Annual Review of Genetics

A review of copper concentrations in Iranian populations

(2019) Samaneh Torkian et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents

(2019) Sergei Perov et al.   PLoS Pathogens

Polyphosphates diminish solubility of a globular protein and thereby promote amyloid aggregation

(2019) Kenji Sasahara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal ions and redox balance regulate distinct amyloid-like aggregation pathways of GAPR-1

(2019) Jie Sheng et al.   Scientific Reports

Regulation of α-synuclein by chaperones in mammalian cells

(2019) Björn M. Burmann et al.   NATURE

Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A

(2019) Christoph Göbl et al.   Redox Biology

Bacterial Model Membranes Reshape Fibrillation of a Functional Amyloid Protein

(2018) Ravit Malishev et al.   BIOCHEMISTRY

Analysis of the Role of the Conserved Disulfide in Amyloid Formation by Human Islet Amyloid Polypeptide in Homogeneous and Heterogeneous Environments

(2018) Zachary Ridgway et al.   BIOCHEMISTRY

Role of the Disulfide Bond in Prion Protein Amyloid Formation: A Thermodynamic and Kinetic Analysis

(2018) Ryo Honda   BIOPHYSICAL JOURNAL

Reversible, functional amyloids: towards an understanding of their regulation in yeast and humans

(2018) Gea Cereghetti et al.   CELL CYCLE

The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS

(2018) Shannon Rhoads et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils

(2018) Surabhi Mehra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A hydrophobic low-complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregatesin vitro

(2018) Erica Grignaschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid assembly and disassembly

(2018) Edward Chuang et al.   JOURNAL OF CELL SCIENCE

Why Study Functional Amyloids? Lessons from the Repeat Domain of Pmel17

(2018) Ryan P. McGlinchey et al.   JOURNAL OF MOLECULAR BIOLOGY

Organization and Function of Non-dynamic Biomolecular Condensates

(2018) Jeffrey B. Woodruff et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111

(2018) Wen-Chang Xu et al.   Cell Death & Disease

Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery

(2018) Sonja Kroschwald et al.   Cell Reports

A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation

(2018) Patrizia Marinelli et al.   Redox Biology

A new era for understanding amyloid structures and disease

(2018) Matthew G. Iadanza et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inorganic polyphosphate, a multifunctional polyanionic protein scaffold

(2018) Lihan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metals and neurodegenerative diseases. A systematic review

(2017) Calogero Edoardo Cicero et al.   ENVIRONMENTAL RESEARCH

Galectin-8–mediated selective autophagy protects against seeded tau aggregation

(2017) Benjamin Falcon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An acetylation–phosphorylation switch that regulates tau aggregation propensity and function

(2017) Yari Carlomagno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetic Insights into Zn2+-Induced Amyloid β-Protein Aggregation Revealed by Stopped-Flow Fluorescence Spectroscopy

(2017) Jingjing Guo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress

(2017) Shady Saad et al.   NATURE CELL BIOLOGY

Nucleation and growth of a bacterial functional amyloid at single-fiber resolution

(2017) Mike Sleutel et al.   Nature Chemical Biology

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis

(2017) Shuzhen Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From structure to redox: The diverse functional roles of disulfides and implications in disease

(2017) Tyler J. Bechtel et al.   PROTEOMICS

Emerging Insights into the Functions of Pathogenesis-Related Protein 1

(2017) Susan Breen et al.   TRENDS IN PLANT SCIENCE

Molecular interactions of amyloid nanofibrils with biological aggregation modifiers: implications for cytotoxicity mechanisms and biomaterial design

(2017) Durga Dharmadana et al.   Interface Focus

Semen amyloids participate in spermatozoa selection and clearance

(2017) Nadia R Roan et al.   eLife

Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein

(2017) Yue Li et al.   Acta Crystallographica Section D-Structural Biology

Crystal Structure of MpPR-1i, a SCP/TAPS protein from Moniliophthora perniciosa, the fungus that causes Witches’ Broom Disease of Cacao

(2017) Renata M. Baroni et al.   Scientific Reports

How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal

(2016) Jack H. Kaplan et al.   BIOPHYSICAL JOURNAL

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism

(2016) Shambaditya Saha et al.   CELL

Adaptation to Stressors by Systemic Protein Amyloidogenesis

(2016) Timothy E. Audas et al.   DEVELOPMENTAL CELL

Cellular proteostasis: degradation of misfolded proteins by lysosomes

(2016) M. P. Jackson et al.   Essays in Biochemistry

Mechanistic Insights into Hsp104 Potentiation

(2016) Mariana P. Torrente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43

(2016) Takashi Nonaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyphosphate: A Conserved Modifier of Amyloidogenic Processes

(2016) Claudia M. Cremers et al.   MOLECULAR CELL

The removal of disulfide bonds in amylin oligomers leads to the conformational change of the ‘native’ amylin oligomers

(2016) Vered Wineman-Fisher et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Wheat PR-1 proteins are targeted by necrotrophic pathogen effector proteins

(2016) Susan Breen et al.   PLANT JOURNAL

Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein

(2016) Rabih Darwiche et al.   Scientific Reports

The fertilization-induced zinc spark is a novel biomarker of mouse embryo quality and early development

(2016) Nan Zhang et al.   Scientific Reports

Good Amyloid, Bad Amyloid—What’s the Difference?

(2016) Roland G. Roberts   PLOS BIOLOGY

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

(2016) Matthias Christoph Munder et al.   eLife

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules

(2016) Reeba S. Jacob et al.   Scientific Reports

Zinc levels in seminal plasma and their correlation with male infertility: A systematic review and meta-analysis

(2016) Jiang Zhao et al.   Scientific Reports

Bivalent Copper Ions Promote Fibrillar Aggregation of KCTD1 and Induce Cytotoxicity

(2016) Zhepeng Liu et al.   Scientific Reports

Arresting Amyloid with Coulomb’s Law: Acetylation of ALS-Linked SOD1 by Aspirin Impedes Aggregation

(2015) Alireza Abdolvahabi et al.   BIOPHYSICAL JOURNAL

Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress

(2015) Edward W.J. Wallace et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

The basics of thiols and cysteines in redox biology and chemistry

(2015) Leslie B. Poole   FREE RADICAL BIOLOGY AND MEDICINE

The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation

(2015) Madhuri Chattopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation

(2015) Tina Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization

(2015) Juan I. Ernesto et al.   JOURNAL OF CELL BIOLOGY

Chaperones in Neurodegeneration

(2015) I. Lindberg et al.   JOURNAL OF NEUROSCIENCE

Structural and functional analysis of BB0689 from Borrelia burgdorferi , a member of the bacterial CAP superfamily

(2015) Kalvis Brangulis et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

(2015) Clara Iannuzzi et al.   MOLECULES

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

(2015) Natura Myeku et al.   NATURE MEDICINE

Autophagy in Alzheimer’s disease

(2015) Ameneh Zare-shahabadi et al.   REVIEWS IN THE NEUROSCIENCES

An acetylation switch controls TDP-43 function and aggregation propensity

(2015) Todd J. Cohen et al.   Nature Communications

LK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegeneration

(2015) Shiqing Zhang et al.   Scientific Reports

The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member fromAncylostoma caninum

(2015) Dongying Ma et al.   Acta Crystallographica Section F-Structural Biology Communications

Amyloid Properties of the Mouse Egg Zona Pellucida

(2015) Nathan Egge et al.   PLoS One

Golgi-Associated plant Pathogenesis Related protein 1 (GAPR-1) forms amyloid-like fibrils by interaction with acidic phospholipids and inhibits Aβ aggregation

(2014) Nick K. Olrichs et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid BMAA

(2014) Oskar Karlsson et al.   ARCHIVES OF TOXICOLOGY

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

(2014) Mi-Hyang Cho et al.   Autophagy

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity

(2014) Kristen E. Funk et al.   BIOCHEMICAL JOURNAL

Acetylation of Gly1 and Lys2 Promotes Aggregation of Human γD-Crystallin

(2014) Michael A. DiMauro et al.   BIOCHEMISTRY

Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events

(2014) Meredith E. Jackrel et al.   CELL

Heparin binding confers prion stability and impairs its aggregation

(2014) Tuane C. R. G. Vieira et al.   FASEB JOURNAL

Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

(2014) Arunagiri Anoop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysophospholipid-Containing Membranes Modulate the Fibril Formation of the Repeat Domain of a Human Functional Amyloid, Pmel17

(2014) Zhiping Jiang et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional Amyloids in the Mouse Sperm Acrosome

(2014) B. Guyonnet et al.   MOLECULAR AND CELLULAR BIOLOGY

A dimeric PR-1-type pathogenesis-related protein interacts with ToxA and potentially mediates ToxA-induced necrosis in sensitive wheat

(2014) Shunwen Lu et al.   MOLECULAR PLANT PATHOLOGY

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

(2014) Sami J Barmada et al.   Nature Chemical Biology

Proteostasis impairment in protein-misfolding and -aggregation diseases

(2014) Mark S. Hipp et al.   TRENDS IN CELL BIOLOGY

Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Disease

(2014) Sandra Tenreiro et al.   PLoS Genetics

Structure ofOstertagia ostertagiASP-1: insights into disulfide-mediated cyclization and dimerization

(2013) Jimmy Borloo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Probing the interplay between amyloidogenic proteins and membranes using lipid monolayers and bilayers

(2013) Annalisa Relini et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid β 42

(2013) Jihoon Nah et al.   Autophagy

New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity

(2013) Carole Anne De Carufel et al.   BIOPOLYMERS

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

The role of protein glycosylation in Alzheimer disease

(2013) Sophia Schedin-Weiss et al.   FEBS Journal

HDAC6 Regulates Mutant SOD1 Aggregation through Two SMIR Motifs and Tubulin Acetylation

(2013) Jozsef Gal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Protein Function and Signaling by Reversible CysteineS-Nitrosylation

(2013) Neal Gould et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Tau phosphorylation affects its axonal transport and degradation

(2013) Teresa Rodríguez-Martín et al.   NEUROBIOLOGY OF AGING

Disulfide bonds in amyloidogenesis diseases related proteins

(2013) Yang Li et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization

(2012) Josse van Galen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid and Nonamyloid Clients

(2012) Morgan E. DeSantis et al.   CELL

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein

(2012) Weijiao Huang et al.   CELL RESEARCH

Hsp104 Drives “Protein-Only” Positive Selection of Sup35 Prion Strains Encoding Strong [PSI+]

(2012) Morgan E. DeSantis et al.   CHEMISTRY & BIOLOGY

Metal ions as modulators of protein conformation and misfolding in neurodegeneration

(2012) Sónia S. Leal et al.   COORDINATION CHEMISTRY REVIEWS

Prolactin and Growth Hormone Aggregates in Secretory Granules: The Need to Understand the Structure of the Aggregate

(2012) Priscilla S. Dannies   ENDOCRINE REVIEWS

Imaging free zinc levels in vivo – What can be learned?

(2012) Luis De Leon-Rodriguez et al.   INORGANICA CHIMICA ACTA

A PR-1-like Protein ofFusarium oxysporumFunctions in Virulence on Mammalian Hosts

(2012) Rafael C. Prados-Rosales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates

(2012) Theodora Saridaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Dimerization and protease resistance: New insight into the function of PR-1

(2012) Shunwen Lu et al.   JOURNAL OF PLANT PHYSIOLOGY

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Zinc in Specialized Secretory Tissues: Roles in the Pancreas, Prostate, and Mammary Gland

(2012) Shannon L. Kelleher et al.   Advances in Nutrition

Structure of a two-CAP-domain protein from the human hookworm parasiteNecator americanus

(2011) Oluwatoyin A. Asojo   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Heparin Binds 8 kDa Gelsolin Cross-β-Sheet Oligomers and Accelerates Amyloidogenesis by Hastening Fibril Extension

(2011) James P. Solomon et al.   BIOCHEMISTRY

Sulfated Glycosaminoglycans Accelerate Transthyretin Amyloidogenesis by Quaternary Structural Conversion

(2011) Steve Bourgault et al.   BIOCHEMISTRY

Evidence for the Involvement of Zinc in the Association of CRISP1 with Rat Sperm During Epididymal Maturation

(2011) J. A. Maldera et al.   BIOLOGY OF REPRODUCTION

Identification of Distinct Populations of Prostasomes That Differentially Express Prostate Stem Cell Antigen, Annexin A1, and GLIPR2 in Humans1

(2011) Marian Aalberts et al.   BIOLOGY OF REPRODUCTION

Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

(2011) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Glycosaminoglycans, Protein Aggregation and Neurodegeneration

(2011) Papy-Garcia Dulce et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Epididymal Protein CRISP1 Plays Different Roles During the Fertilization Process

(2011) D. J. Cohen et al.   JOURNAL OF ANDROLOGY

Hyperphosphorylation as a Defense Mechanism to Reduce TDP-43 Aggregation

(2011) Huei-Ying Li et al.   PLoS One

Cysteine-Rich Secretory Protein-3 (CRISP3) Is Strongly Up-Regulated in Prostate Carcinomas with the TMPRSS2-ERG Fusion Gene

(2011) Franclim R. Ribeiro et al.   PLoS One

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biogenesis and function of nuclear bodies

(2011) Yuntao S. Mao et al.   TRENDS IN GENETICS

Strengthening relationships: amyloids create adhesion nanodomains in yeasts

(2011) Peter N. Lipke et al.   TRENDS IN MICROBIOLOGY

Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

(2011) Brenda Watt et al.   PLoS Genetics

Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases

(2010) Jacques Fantini et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity

(2010) Massimo Stefani   FEBS Journal

Cobra CRISP Functions as an Inflammatory Modulator via a Novel Zn2+- and Heparan Sulfate-dependent Transcriptional Regulation of Endothelial Cell Adhesion Molecules

(2010) Yu-Ling Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment

(2010) Shelly Adi-Harel et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Effect of the Disulfide Bond on the Monomeric Structure of Human Amylin Studied by Combined Hamiltonian and Temperature Replica Exchange Molecular Dynamics Simulations

(2010) Rozita Laghaei et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein aggregation diseases: pathogenicity and therapeutic perspectives

(2010) Adriano Aguzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Evidence for a Partially Structured State of the Amylin Monomer

(2009) Sara M. Vaiana et al.   BIOPHYSICAL JOURNAL

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

(2009) Olga V Moroz et al.   BMC BIOCHEMISTRY

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

The Role of Thiols and Disulfides on Protein Stability

(2009) Maulik Trivedi et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

(2009) Brenda Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits

(2009) X.-m. Zha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc is an essential trace element for spermatogenesis

(2009) S. Yamaguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation

(2009) R. Narayanaswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Amylin Proprotein Processing Generates Progressively More Amyloidogenic Peptides that Initially Sample the Helical State†

(2008) Isaac T. Yonemoto et al.   BIOCHEMISTRY

Glioma Pathogenesis-Related Protein 1 Exerts Tumor Suppressor Activities through Proapoptotic Reactive Oxygen Species c-Jun NH2 Kinase Signaling

(2008) L. Li et al.   CANCER RESEARCH

The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune Defense

(2008) Gerard M. Gibbs et al.   ENDOCRINE REVIEWS

Crisp proteins and sperm chemotaxis: discovery in amphibians and explorations in mammals

(2008) Lindsey A. Burnett et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The role of the acrosomal matrix in fertilization

(2008) Mariano G. Buffone et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Dynamics of component exchange at PML nuclear bodies

(2008) S. Weidtkamp-Peters et al.   JOURNAL OF CELL SCIENCE

Purification and multimer formation of allurin, a sperm chemoattractant fromXenopus laevisegg jelly

(2008) Hitoshi Sugiyama et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT