New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity

Ionic Strength Effects on Amyloid Formation by Amylin Are a Complicated Interplay among Debye Screening, Ion Selectivity, and Hofmeister Effects

(2012) Peter J. Marek et al.   BIOCHEMISTRY

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates

(2012) Theodora Saridaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid Formation in Heterogeneous Environments: Islet Amyloid Polypeptide Glycosaminoglycan Interactions

(2012) Hui Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate

(2012) Neda Motamedi-Shad et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

(2011) Steve Bourgault et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heparin Binds 8 kDa Gelsolin Cross-β-Sheet Oligomers and Accelerates Amyloidogenesis by Hastening Fibril Extension

(2011) James P. Solomon et al.   BIOCHEMISTRY

Sulfated Glycosaminoglycans Accelerate Transthyretin Amyloidogenesis by Quaternary Structural Conversion

(2011) Steve Bourgault et al.   BIOCHEMISTRY

Mechanism of Amylin Fibrillization Enhancement by Heparin

(2011) Suman Jha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

Heparin Induces Harmless Fibril Formation in Amyloidogenic W7FW14F Apomyoglobin and Amyloid Aggregation in Wild-Type Protein In Vitro

(2011) Silvia Vilasi et al.   PLoS One

The Flavanol (−)-Epigallocatechin 3-Gallate Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity

(2010) Fanling Meng et al.   BIOCHEMISTRY

Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin

(2010) Jillian Madine et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Heparan sulfate mediates amyloid-beta internalization and cytotoxicity

(2010) Elina Sandwall et al.   GLYCOBIOLOGY

The Sulfated Triphenyl Methane Derivative Acid Fuchsin Is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation

(2010) Fanling Meng et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanistic Studies of Peptide Self-Assembly: Transient α-Helices to Stable β-Sheets

(2010) Gai Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X

(2010) Angela C. Bradshaw et al.   PLoS Pathogens

Common features between diabetes mellitus and Alzheimer’s disease

(2009) J. Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kinetic Analysis of Amyloid Formation in the Presence of Heparan Sulfate

(2009) Neda Motamedi-Shad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

(2009) A. Abedini et al.   PROTEIN ENGINEERING DESIGN & SELECTION