The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL

(2015) T. Burgoyne et al.   JOURNAL OF CELL SCIENCE

ADAM protease inhibitors reduce melanogenesis by regulating PMEL17 processing in human melanocytes

(2015) Masakazu Kawaguchi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

(2015) Margery L. Evans et al.   MOLECULAR CELL

Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

(2014) Arunagiri Anoop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Forming disulfides in the endoplasmic reticulum

(2013) Ojore B.V. Oka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils

(2013) Ralf M. Leonhardt et al.   MOLECULAR BIOLOGY OF THE CELL

PMEL: a pigment cell-specific model for functional amyloid formation

(2013) Brenda Watt et al.   Pigment Cell & Melanoma Research

BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells

(2013) L. Rochin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the role of disulfide bonds on the amyloid formation of insulin

(2012) Yang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

Expanding roles for GILT in immunity

(2012) Laura Ciaccia West et al.   CURRENT OPINION IN IMMUNOLOGY

Using Intramolecular Disulfide Bonds in Tau Protein to Deduce Structural Features of Aggregation-resistant Conformations

(2012) Sophie Walker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export

(2012) S.-S. Chng et al.   SCIENCE

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Proprotein Convertases Process Pmel17 during Secretion

(2011) Ralf M. Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

(2011) Brenda Watt et al.   PLoS Genetics

Inactivation of Pmel Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation

(2011) Anders R. Hellström et al.   PLoS Genetics

Endoplasmic Reticulum Export, Subcellular Distribution, and Fibril Formation by Pmel17 Require an Intact N-terminal Domain Junction

(2010) Ralf M. Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding

(2009) Toshihiko Hoashi et al.   FASEB JOURNAL

N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

(2009) Brenda Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF

(2009) Ashley A. Nenninger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of Pmel17 Amyloid Is Regulated by Juxtamembrane Metalloproteinase Cleavage, and the Resulting C-terminal Fragment Is a Substrate for γ-Secretase

(2008) Markus P. Kummer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human IgG2 Antibody Disulfide Rearrangementin Vivo

(2008) Y. Diana Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets

(2008) I. Hurbain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA