Metal ions and redox balance regulate distinct amyloid-like aggregation pathways of GAPR-1

Zinc binding regulates amyloid-like aggregation of GAPR-1

(2019) Jie Sheng et al.   BIOSCIENCE REPORTS

NMR Measurements Reveal the Structural Basis of Transthyretin Destabilization by Pathogenic Mutations

(2018) Benjamin I. Leach et al.   BIOCHEMISTRY

Reversible, functional amyloids: towards an understanding of their regulation in yeast and humans

(2018) Gea Cereghetti et al.   CELL CYCLE

A hydrophobic low-complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregatesin vitro

(2018) Erica Grignaschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The function of yeast CAP family proteins in lipid export, mating, and pathogen defense

(2017) Rabih Darwiche et al.   FEBS LETTERS

Zinc in Cellular Regulation: The Nature and Significance of “Zinc Signals”

(2017) Wolfgang Maret   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production

(2017) Hermeto Gerber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into the mechanism of cystatin C oligomer and amyloid formation and its interaction with β-amyloid

(2017) Tyler J. Perlenfein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tracing the Evolutionary History of the CAP Superfamily of Proteins Using Amino Acid Sequence Homology and Conservation of Splice Sites

(2017) Anup Abraham et al.   JOURNAL OF MOLECULAR EVOLUTION

Cross talk between neurometals and amyloidogenic proteins at the synapse and the pathogenesis of neurodegenerative diseases

(2017) M. Kawahara et al.   Metallomics

Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress

(2017) Shady Saad et al.   NATURE CELL BIOLOGY

Evaluating the effect of mutations and ligand binding on transthyretin homotetramer dynamics

(2017) Tadeo. E. Saldaño et al.   PLoS One

MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis

(2017) Shuzhen Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging Insights into the Functions of Pathogenesis-Related Protein 1

(2017) Susan Breen et al.   TRENDS IN PLANT SCIENCE

Semen amyloids participate in spermatozoa selection and clearance

(2017) Nadia R Roan et al.   eLife

Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein

(2017) Yue Li et al.   Acta Crystallographica Section D-Structural Biology

How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal

(2016) Jack H. Kaplan et al.   BIOPHYSICAL JOURNAL

Adaptation to Stressors by Systemic Protein Amyloidogenesis

(2016) Timothy E. Audas et al.   DEVELOPMENTAL CELL

Human cystatin C monomer, dimer, oligomer, and amyloid structures are related to health and disease

(2016) Przemyslaw Jurczak et al.   FEBS LETTERS

Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein

(2016) Rabih Darwiche et al.   Scientific Reports

Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer

(2016) Irina Iakovleva et al.   PLoS One

Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules

(2016) Reeba S. Jacob et al.   Scientific Reports

The Golgi-Associated Plant Pathogenesis-Related Protein GAPR-1 Enhances Type I Interferon Signaling Pathway in Response to Toll-Like Receptor 4

(2015) Qing Zhou et al.   INFLAMMATION

The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation

(2015) Madhuri Chattopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thiol redox homeostasis in neurodegenerative disease

(2015) Gethin J. McBean et al.   Redox Biology

Golgi-Associated plant Pathogenesis Related protein 1 (GAPR-1) forms amyloid-like fibrils by interaction with acidic phospholipids and inhibits Aβ aggregation

(2014) Nick K. Olrichs et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

(2014) Arunagiri Anoop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A dimeric PR-1-type pathogenesis-related protein interacts with ToxA and potentially mediates ToxA-induced necrosis in sensitive wheat

(2014) Shunwen Lu et al.   MOLECULAR PLANT PATHOLOGY

Age-Related Oxidative Modifications of Transthyretin Modulate Its Amyloidogenicity

(2013) Lei Zhao et al.   BIOCHEMISTRY

Salivary Antigen-5/CAP Family Members Are Cu2+-dependent Antioxidant Enzymes That Scavenge O2⨪and Inhibit Collagen-induced Platelet Aggregation and Neutrophil Oxidative Burst

(2013) Teresa C. F. Assumpção et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization

(2012) Josse van Galen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Dimerization and protease resistance: New insight into the function of PR-1

(2012) Shunwen Lu et al.   JOURNAL OF PLANT PHYSIOLOGY

Pathogen-Related Yeast (PRY) proteins and members of the CAP superfamily are secreted sterol-binding proteins

(2012) V. Choudhary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for the Involvement of Zinc in the Association of CRISP1 with Rat Sperm During Epididymal Maturation

(2011) J. A. Maldera et al.   BIOLOGY OF REPRODUCTION

Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

(2011) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Tau Protein Assembles into Isoform- and Disulfide-dependent Polymorphic Fibrils with Distinct Structural Properties

(2011) Yoshiaki Furukawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism

(2011) Ruma Banerjee   JOURNAL OF BIOLOGICAL CHEMISTRY

Cobra CRISP Functions as an Inflammatory Modulator via a Novel Zn2+- and Heparan Sulfate-dependent Transcriptional Regulation of Endothelial Cell Adhesion Molecules

(2010) Yu-Ling Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis

(2009) Ashutosh Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain

(2008) Nobuhiro Suzuki et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune Defense

(2008) Gerard M. Gibbs et al.   ENDOCRINE REVIEWS

Purification and multimer formation of allurin, a sperm chemoattractant fromXenopus laevisegg jelly

(2008) Hitoshi Sugiyama et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT