Molecular interactions of amyloid nanofibrils with biological aggregation modifiers: implications for cytotoxicity mechanisms and biomaterial design

Amyloid Fibrils as Building Blocks for Natural and Artificial Functional Materials

(2016) Tuomas P. J. Knowles et al.   ADVANCED MATERIALS

Amyloid Aggregates Arise from Amino Acid Condensations under Prebiotic Conditions

(2016) Jason Greenwald et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell Adhesion on Amyloid Fibrils Lacking Integrin Recognition Motif

(2016) Reeba S. Jacob et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer⿿s disease

(2016) Cecilia Wallin et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Coassembled nanostructured bioscaffold reduces the expression of proinflammatory cytokines to induce apoptosis in epithelial cancer cells

(2016) Rui Li et al.   Nanomedicine-Nanotechnology Biology and Medicine

The activities of amyloids from a structural perspective

(2016) Roland Riek et al.   NATURE

Amyloid–carbon hybrid membranes for universal water purification

(2016) Sreenath Bolisetty et al.   Nature Nanotechnology

Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper

(2016) Shin Jung C. Lee et al.   Chemical Science

Implantable amyloid hydrogels for promoting stem cell differentiation to neurons

(2016) Subhadeep Das et al.   NPG Asia Materials

Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones

(2016) Jonathan D. Taylor et al.   Scientific Reports

Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells

(2016) Anna Drews et al.   Scientific Reports

Functional Organic Semiconductors Assembled via Natural Aggregating Peptides

(2015) Galen L. Eakins et al.   ADVANCED FUNCTIONAL MATERIALS

Amyloid Templated Gold Aerogels

(2015) Gustav Nyström et al.   ADVANCED MATERIALS

Microtubule-Binding R3 Fragment from Tau Self-Assembles into Giant Multistranded Amyloid Ribbons

(2015) Jozef Adamcik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Topography and Chemistry Control Cell Attachment to Amyloid Fibrils

(2015) Nicholas P. Reynolds et al.   BIOMACROMOLECULES

Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation

(2015) Reeba S. Jacob et al.   BIOMATERIALS

β-Sheet interfering molecules acting against β-amyloid aggregation and fibrillogenesis

(2015) Antonio Francioso et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death

(2015) A-L Mahul-Mellier et al.   CELL DEATH AND DIFFERENTIATION

Structural, morphological, and functional diversity of amyloid oligomers

(2015) Leonid Breydo et al.   FEBS LETTERS

Hybrid Amyloid Membranes for Continuous Flow Catalysis

(2015) Sreenath Bolisetty et al.   LANGMUIR

GM1 Ganglioside: Past Studies and Future Potential

(2015) Massimo Aureli et al.   MOLECULAR NEUROBIOLOGY

The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

(2015) Clara Iannuzzi et al.   MOLECULES

On the lag phase in amyloid fibril formation

(2015) Paolo Arosio et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Crystallin Nanofibrils: A Functionalizable Nanoscaffold with Broad Applications Manufactured from Waste

(2015) Manmeet Kaur et al.   ChemPlusChem

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

(2015) Erik Chorell et al.   PLoS One

Metal Ions and Intrinsically Disordered Proteins and Peptides: From Cu/Zn Amyloid-β to General Principles

(2014) Peter Faller et al.   ACCOUNTS OF CHEMICAL RESEARCH

Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity

(2014) Benedetta Mannini et al.   ACS Chemical Biology

Multiwalled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles

(2014) Yi-An Lin et al.   ACS Nano

Protein/Lipid Coaggregates are Formed During α-Synuclein-Induced Disruption of Lipid Bilayers

(2014) Andreas van Maarschalkerweerd et al.   BIOMACROMOLECULES

Amyloid Fibrils Enhance Transport of Metal Nanoparticles in Living Cells and Induced Cytotoxicity

(2014) Sreenath Bolisetty et al.   BIOMACROMOLECULES

Engineered Lysozyme Amyloid Fibril Networks Support Cellular Growth and Spreading

(2014) Nicholas P. Reynolds et al.   BIOMACROMOLECULES

Amyloids of Alpha-Synuclein Affect the Structure and Dynamics of Supported Lipid Bilayers

(2014) Aditya Iyer et al.   BIOPHYSICAL JOURNAL

Amyloid-based nanosensors and nanodevices

(2014) Charlotte A. E. Hauser et al.   CHEMICAL SOCIETY REVIEWS

Functional amyloid: widespread in Nature, diverse in purpose

(2014) Chi L.L. Pham et al.   Essays in Biochemistry

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

(2014) Alexander K. Buell et al.   Essays in Biochemistry

Heparin binding confers prion stability and impairs its aggregation

(2014) Tuane C. R. G. Vieira et al.   FASEB JOURNAL

Membrane interactions and fibrillization of α-synuclein play an essential role in membrane disruption

(2014) Himanshu Chaudhary et al.   FEBS LETTERS

Differential Effects on Light Chain Amyloid Formation Depend on Mutations and Type of Glycosaminoglycans

(2014) Luis M. Blancas-Mejía et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How to Determine the Size of Folding Nuclei of Protofibrils from the Concentration Dependence of the Rate and Lag-Time of Aggregation. I. Modeling the Amyloid Protofibril Formation

(2014) Nikita V. Dovidchenko et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Characterization of biometal profiles in neurological disorders

(2014) Stefanie Pfaender et al.   Metallomics

Hybrid Nanocomposites of Gold Single-Crystal Platelets and Amyloid Fibrils with Tunable Fluorescence, Conductivity, and Sensing Properties

(2013) Chaoxu Li et al.   ADVANCED MATERIALS

Nanotopographic Surfaces with Defined Surface Chemistries from Amyloid Fibril Networks Can Control Cell Attachment

(2013) Nicholas P. Reynolds et al.   BIOMACROMOLECULES

Cations as Switches of Amyloid-Mediated Membrane Disruption Mechanisms: Calcium and IAPP

(2013) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity

(2013) Carole Anne De Carufel et al.   BIOPOLYMERS

Beta-adrenoceptor antagonists affect amyloid nanostructure; amyloid hydrogels as drug delivery vehicles

(2013) Jenifer Mains et al.   CHEMICAL COMMUNICATIONS

α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling

(2013) Myriam M. Ouberai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Lipid Co-Aggregation with α-Synuclein Fibrils

(2013) Erik Hellstrand et al.   PLoS One

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Tafamidis on Transthyretin Stabilization and Clinical Outcomes in Patients with Non-Val30Met Transthyretin Amyloidosis

(2013) Giampaolo Merlini et al.   Journal of Cardiovascular Translational Research

Copper prevents amyloid-β1–42 from forming amyloid fibrils under near-physiological conditions in vitro

(2013) Matthew Mold et al.   Scientific Reports

Phosphatidylethanolamine Enhances Amyloid Fiber-Dependent Membrane Fragmentation

(2012) Michele F. M. Sciacca et al.   BIOCHEMISTRY

Amyloid-Like Fibril Formation by Tachykinin Neuropeptides and Its Relevance to Amyloid β-Protein Aggregation and Toxicity

(2012) Pradeep K. Singh et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Metal ions as modulators of protein conformation and misfolding in neurodegeneration

(2012) Sónia S. Leal et al.   COORDINATION CHEMISTRY REVIEWS

Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation

(2012) Igor F. Tsigelny et al.   FEBS Journal

Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates

(2012) Theodora Saridaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Radiating Amyloid Fibril Formation on the Surface of Lipid Membranes through Unit-Assembly of Oligomeric Species of α-Synuclein

(2012) Jung-Ho Lee et al.   PLoS One

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

(2012) L. Milanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

(2012) C. E. Bulawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparin Binds 8 kDa Gelsolin Cross-β-Sheet Oligomers and Accelerates Amyloidogenesis by Hastening Fibril Extension

(2011) James P. Solomon et al.   BIOCHEMISTRY

Sulfated Glycosaminoglycans Accelerate Transthyretin Amyloidogenesis by Quaternary Structural Conversion

(2011) Steve Bourgault et al.   BIOCHEMISTRY

Functional fibrils derived from the peptide TTR1-cycloRGDfK that target cell adhesion and spreading

(2011) Marie N. Bongiovanni et al.   BIOMATERIALS

Misfolded proteins in Alzheimer's disease and type II diabetes

(2011) Alaina S. DeToma et al.   CHEMICAL SOCIETY REVIEWS

Dynamics of ZnII Binding as a Key Feature in the Formation of Amyloid Fibrils by Aβ11-28

(2011) Bruno Alies et al.   INORGANIC CHEMISTRY

Aluminum, copper, iron and zinc differentially alter amyloid-Aβ1–42 aggregation and toxicity

(2011) Silvia Bolognin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Single-channel Ca2+imaging implicates Aβ1–42 amyloid pores in Alzheimer’s disease pathology

(2011) Angelo Demuro et al.   JOURNAL OF CELL BIOLOGY

α-Synuclein-Induced Tubule Formation in Lipid Bilayers

(2011) Anjan P. Pandey et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Metastability of Native Proteins and the Phenomenon of Amyloid Formation

(2011) Andrew J. Baldwin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Membrane Interaction and Disruption by α-Synuclein

(2011) Nicholas P. Reynolds et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity, biogenesis and function of microbial amyloids

(2011) Luz P. Blanco et al.   TRENDS IN MICROBIOLOGY

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioresponsive peptide–inorganic hybrid nanomaterials

(2010) Daniel Aili et al.   CHEMICAL SOCIETY REVIEWS

Stimulus responsive peptide based materials

(2010) Dennis W. P. M. Löwik et al.   CHEMICAL SOCIETY REVIEWS

More than just bare scaffolds: towards multi-component and decorated fibrous biomaterials

(2010) Derek N. Woolfson et al.   CHEMICAL SOCIETY REVIEWS

Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure

(2010) Juan José Valle-Delgado et al.   FASEB JOURNAL

Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species

(2010) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

(2010) Jobin Varkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease

(2010) Claire J. Sarell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins†

(2009) Jerson L. Silva et al.   ACCOUNTS OF CHEMICAL RESEARCH

Deprotonation of the Asp1Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid-β Peptide near Physiological pH

(2009) Christelle Hureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cholesterol Modulates the Interaction of β-Amyloid Peptide with Lipid Bilayers

(2009) Liming Qiu et al.   BIOPHYSICAL JOURNAL

Interaction Between Amyloid-β (1–42) Peptide and Phospholipid Bilayers: A Molecular Dynamics Study

(2009) Charles H. Davis et al.   BIOPHYSICAL JOURNAL

Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts

(2009) Masaki Wakabayashi et al.   FEBS LETTERS

Amyloid Formation by the Model Protein Muscle Acylphosphatase is Accelerated by Heparin and Heparan Sulphate Through a Scaffolding-based Mechanism

(2009) N. Motamedi-Shad et al.   JOURNAL OF BIOCHEMISTRY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Functional Amyloids Signal Their Arrival

(2009) M. P. Badtke et al.   Science Signaling

Amyloids: Not Only Pathological Agents but Also Ordered Nanomaterials

(2008) Izhack Cherny et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu(II) Binding to Monomeric, Oligomeric, and Fibrillar Forms of the Alzheimer’s Disease Amyloid-β Peptide†

(2008) Jesse W. Karr et al.   BIOCHEMISTRY

Soluble Amyloid β-Oligomers Affect Dielectric Membrane Properties by Bilayer Insertion and Domain Formation: Implications for Cell Toxicity

(2008) Gintaras Valincius et al.   BIOPHYSICAL JOURNAL

Protein- and Peptide-Directed Syntheses of Inorganic Materials

(2008) Matthew B. Dickerson et al.   CHEMICAL REVIEWS

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death

(2008) Sandrine Greffard et al.   NEUROBIOLOGY OF AGING

Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

(2008) Eva Y. Chi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

Islet Amyloid Polypeptide Forms Rigid Lipid–Protein Amyloid Fibrils on Supported Phospholipid Bilayers

(2007) Yegor A. Domanov et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane Fusogenic Activity of the Alzheimer's Peptide Aβ(1–42) Demonstrated by Small-Angle Neutron Scattering

(2007) Silvia Dante et al.   JOURNAL OF MOLECULAR BIOLOGY

α-Synuclein Selectively Binds to Anionic Phospholipids Embedded in Liquid-Disordered Domains

(2007) Martin Stöckl et al.   JOURNAL OF MOLECULAR BIOLOGY