NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy

Mitochondrial Stability in Diabetic Retinopathy: Lessons Learned From Epigenetics

(2019) Renu A. Kowluru   DIABETES

Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury

(2019) Alexey Pronin et al.   Frontiers in Molecular Neuroscience

Pannexin 1 Channels Contribute to IL-1β Expression via NLRP3/Caspase-1 Inflammasome in Aspergillus Fumigatus Keratitis

(2019) Xuejiao Yang et al.   CURRENT EYE RESEARCH

NLRP3 inflammasome in NMDA-induced retinal excitotoxicity

(2019) Pavlina Tsoka et al.   EXPERIMENTAL EYE RESEARCH

Characterization of a functionally active primary microglial cell culture from the pig retina

(2019) Rayne R. Lim et al.   EXPERIMENTAL EYE RESEARCH

Neovascular glaucoma regulation by arylsulfonyl indoline-benzamide (ASIB) through targeting NF-kB signalling pathway

(2019) Xiaojun Lei et al.   3 Biotech

The levels and significance of inflammasomes in the mouse retina following optic nerve crush

(2019) Zheng Qijun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

(2019) Hiroaki Shimizu et al.   Scientific Reports

IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative Diseases

(2019) Yvette Wooff et al.   Frontiers in Immunology

Microglia in Retinal Degeneration

(2019) Khalid Rashid et al.   Frontiers in Immunology

Auranofin Mediates Mitochondrial Dysregulation and Inflammatory Cell Death in Human Retinal Pigment Epithelial Cells: Implications of Retinal Neurodegenerative Diseases

(2019) Thangal Yumnamcha et al.   Frontiers in Neuroscience

NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response

(2018) Yan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release

(2018) Odunayo O. Mugisho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The rescue effect of mesenchymal stem cell on sodium iodate-induced retinal pigment epithelial cell death through deactivation of NF-κB-mediated NLRP3 inflammasome

(2018) Xiying Mao et al.   BIOMEDICINE & PHARMACOTHERAPY

Pyroptosis in pterygium pathogenesis

(2018) Naiyu Sun et al.   BIOSCIENCE REPORTS

Role of Inflammation in Diabetic Retinopathy

(2018) Anne Rübsam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis

(2018) Soumyava Basu et al.   MICROBIAL PATHOGENESIS

Targeting the NLRP3 inflammasome in inflammatory diseases

(2018) Matthew S. J. Mangan et al.   NATURE REVIEWS DRUG DISCOVERY

Methylene Blue Attenuates Diabetic Retinopathy by Inhibiting NLRP3 Inflammasome Activation in STZ-induced Diabetic Rats

(2018) Jingfang Hao et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

(2018) Niina Piippo et al.   Scientific Reports

Cyanidin-3-glucoside Alleviates 4-Hydroxyhexenal-Induced NLRP3 Inflammasome Activation via JNK-c-Jun/AP-1 Pathway in Human Retinal Pigment Epithelial Cells

(2018) Xiaolu Jin et al.   Journal of Immunology Research

Photo-Oxidative Blue-Light Stimulation in Retinal Pigment Epithelium Cells Promotes Exosome Secretion and Increases the Activity of the NLRP3 Inflammasome

(2018) Wei Zhang et al.   CURRENT EYE RESEARCH

Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection

(2018) Yan Sun et al.   JOURNAL OF IMMUNOLOGY

The role of mitochondria in NLRP3 inflammasome activation

(2018) Qiuyun Liu et al.   MOLECULAR IMMUNOLOGY

The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

(2018) Shyam S. Chaurasia et al.   Scientific Reports

Kaempferol attenuates retinal ganglion cell death by suppressing NLRP1/NLRP3 inflammasomes and caspase-8 via JNK and NF-κB pathways in acute glaucoma

(2018) Chaobin Lin et al.   EYE

Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma

(2018) Mohammad Harun-Or-Rashid et al.   Journal of Neuroinflammation

Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice

(2018) Shuai Wang et al.   Molecular Medicine Reports

Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2

(2018) Zhimin Xu et al.   Frontiers in Neuroscience

Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells

(2018) Yiqin Dai et al.   Redox Biology

Puerarin inhibits amyloid β-induced NLRP3 inflammasome activation in retinal pigment epithelial cells via suppressing ROS-dependent oxidative and endoplasmic reticulum stresses

(2017) Ke Wang et al.   EXPERIMENTAL CELL RESEARCH

Inflammasomes, the eye and anti-inflammasome therapy

(2017) P Yerramothu et al.   EYE

Inhibition of TLR4 alleviates the inflammation and apoptosis of retinal ganglion cells in high glucose

(2017) Lili Hu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Corneal Fibroblasts as Sentinel Cells and Local Immune Modulators in Infectious Keratitis

(2017) Ken Fukuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

(2017) Fang Bian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye

(2017) Wei Chi et al.   JOURNAL OF AUTOIMMUNITY

Epac1 Blocks NLRP3 Inflammasome to Reduce IL-1β in Retinal Endothelial Cells and Mouse Retinal Vasculature

(2017) Youde Jiang et al.   MEDIATORS OF INFLAMMATION

Fenofibrate ameliorates diabetic retinopathy by modulating Nrf2 signaling and NLRP3 inflammasome activation

(2017) Qiuping Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Amelioration of amyloid β-induced retinal inflammatory responses by a LXR agonist TO901317 is associated with inhibition of the NF-κB signaling and NLRP3 inflammasome

(2017) Chunyan Lei et al.   NEUROSCIENCE

Strong upregulation of inflammatory genes accompanies photoreceptor demise in canine models of retinal degeneration

(2017) Tatyana Appelbaum et al.   PLoS One

Diabetic retinopathy and dysregulated innate immunity

(2017) Heping Xu et al.   VISION RESEARCH

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

(2017) Farraj Albalawi et al.   Frontiers in Cellular Neuroscience

Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

(2017) Yi Zhang et al.   Cell Death & Disease

TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy

(2017) Takhellambam Swornalata Devi et al.   Cell Death & Disease

NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis

(2017) Sharon A. McClellan et al.   PLoS One

CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulation

(2016) Sijia Cao et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Upregulation of NLRP3 inflammasome components in Mooren’s ulcer

(2016) Zhiyuan Li et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration

(2016) Ishaq A. Viringipurampeer et al.   HUMAN MOLECULAR GENETICS

Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production

(2016) Ke Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Transcription Profiling of NOD-like Receptors in the Human Cornea with Disease

(2016) Joo Youn Oh et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

P2Y1 Receptor Signaling Contributes to High Salt-Induced Priming of the NLRP3 Inflammasome in Retinal Pigment Epithelial Cells

(2016) Philipp Prager et al.   PLoS One

Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light

(2016) Zizhong Hu et al.   Cell Death & Disease

Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice

(2016) Zhen Puyang et al.   Scientific Reports

Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress

(2015) Huanqi Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients

(2015) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy

(2015) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux

(2015) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

(2015) Wei Chi et al.   Journal of Neuroinflammation

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

(2015) M. D. Weber et al.   JOURNAL OF NEUROSCIENCE

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

(2015) Jiangyuan Gao et al.   MEDIATORS OF INFLAMMATION

The crosstalk between TLR2 and NOD2 in Aspergillus fumigatus keratitis

(2015) Jiayin Wu et al.   MOLECULAR IMMUNOLOGY

NOD-Like Receptors: Versatile Cytosolic Sentinels

(2015) Vinicius Motta et al.   PHYSIOLOGICAL REVIEWS

Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy

(2015) Renu A. Kowluru et al.   PROGRESS IN RETINAL AND EYE RESEARCH

CAPS — pathogenesis, presentation and treatment of an autoinflammatory disease

(2015) Jasmin B. Kuemmerle-Deschner   Seminars in Immunopathology

7-Ketocholesterol Increases Retinal Microglial Migration, Activation and Angiogenicity: A Potential Pathogenic Mechanism Underlying Age-related Macular Degeneration

(2015) Maanasa Indaram et al.   Scientific Reports

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome

(2015) Bradley D. Gelfand et al.   Cell Reports

Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells

(2014) Niina Piippo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aspergillus fumigatus triggers innate immune response via NOD1 signaling in human corneal epithelial cells

(2014) Yuting Zhang et al.   EXPERIMENTAL EYE RESEARCH

Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells

(2014) Ruozhou Tom Liu et al.   EXPERIMENTAL EYE RESEARCH

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye

(2014) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

The Evolution of Reproduction-Related NLRP Genes

(2014) Edgar A. Duéñez-Guzmán et al.   JOURNAL OF MOLECULAR EVOLUTION

Anti-Inflammatory Therapy in Diabetic Retinopathy

(2014) Katarzyna Zorena   MEDIATORS OF INFLAMMATION

Chemokine Mediated Monocyte Trafficking into the Retina: Role of Inflammation in Alteration of the Blood-Retinal Barrier in Diabetic Retinopathy

(2014) Sampathkumar Rangasamy et al.   PLoS One

Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1  production in acute glaucoma

(2014) W. Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Description of a new family with cryopyrin-associated periodic syndrome: risk of visual loss in patients bearing the R260W mutation

(2014) N. Alejandre et al.   RHEUMATOLOGY

Microglia and Interleukin-1β in Ischemic Retinopathy Elicit Microvascular Degeneration Through Neuronal Semaphorin-3A

(2013) José Carlos Rivera et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Involvement of HMGB1 mediated signalling pathway in diabetic retinopathy: evidence from type 2 diabetic rats and ARPE-19 cells under diabetic condition

(2013) Xiao-Li Chen et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

(2013) M F El-Azab et al.   BRITISH JOURNAL OF PHARMACOLOGY

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy

(2013) Takhellambam S. Devi et al.   EXPERIMENTAL CELL RESEARCH

Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization

(2013) Alexa Klettner et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cryopyrin-associated Periodic Syndromes and the Eye

(2013) Thomas J. Oberg et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

A2E Induces IL-1ß Production in Retinal Pigment Epithelial Cells via the NLRP3 Inflammasome

(2013) Owen A. Anderson et al.   PLoS One

Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells

(2013) Victoria E. McGilligan et al.   PLoS One

NLRP3 Inflammasome Blockade Inhibits VEGF-A-Induced Age-Related Macular Degeneration

(2013) Alexander G. Marneros   Cell Reports

Hyperreflective Intraretinal Spots in Diabetics without and with Nonproliferative Diabetic Retinopathy: AnIn VivoStudy Using Spectral Domain OCT

(2013) Stela Vujosevic et al.   Journal of Diabetes Research

Unsolved Mysteries in NLR Biology

(2013) Christopher Lupfer et al.   Frontiers in Immunology

HMGB1 Promotes the Synthesis of Pro-IL-1β and Pro-IL-18 by Activation of p38 MAPK and NF-κB Through Receptors for Advanced Glycation End-products in Macrophages

(2012) Qiang He et al.   Asian Pacific Journal of Cancer Prevention

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

Current Epidemiology of Diabetic Retinopathy and Diabetic Macular Edema

(2012) Jie Ding et al.   Current Diabetes Reports

Incidence and Progression of Diabetic Retinopathy During 17 Years of a Population-Based Screening Program in England

(2012) C. D. Jones et al.   DIABETES CARE

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy

(2012) Takhellambam S. Devi et al.   Experimental Diabetes Research

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

The NLRP12 Inflammasome Recognizes Yersinia pestis

(2012) Gregory I. Vladimer et al.   IMMUNITY

An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages

(2012) Sonal Khare et al.   IMMUNITY

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

(2012) Irving C. Allen et al.   IMMUNITY

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

The rhapsody of NLRPs: master players of inflammation … and a lot more

(2012) Lia Paola Zambetti et al.   IMMUNOLOGIC RESEARCH

NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells

(2012) F. Staehli et al.   JOURNAL OF IMMUNOLOGY

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

(2012) Paras K. Anand et al.   NATURE

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

(2012) Monika Schneider et al.   NATURE IMMUNOLOGY

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

(2012) Sarah L Doyle et al.   NATURE MEDICINE

Nlrp2, a Maternal Effect Gene Required for Early Embryonic Development in the Mouse

(2012) Hui Peng et al.   PLoS One

Lymphatics and Lymphangiogenesis in the Eye

(2012) Shintaro Nakao et al.   Journal of Ophthalmology

Good news–bad news: the Yin and Yang of immune privilege in the eye

(2012) John V. Forrester et al.   Frontiers in Immunology

Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1

(2011) Katherine E. Trueblood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Microvascular Modifications in Diabetic Retinopathy

(2011) Jennifer T. Durham et al.   Current Diabetes Reports

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis

(2011) G. Y. Chen et al.   JOURNAL OF IMMUNOLOGY

Adenovirus Type 5 Rupture of Lysosomes Leads to Cathepsin B-Dependent Mitochondrial Stress and Production of Reactive Oxygen Species

(2011) K. A. McGuire et al.   JOURNAL OF VIROLOGY

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

NLR functions beyond pathogen recognition

(2011) Thomas A Kufer et al.   NATURE IMMUNOLOGY

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Diabetic retinopathy

(2010) Ning Cheung et al.   LANCET

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

(2010) L Perrone et al.   Cell Death & Disease

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?

(2009) T M Curtis et al.   EYE

Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions

(2009) Lorena Perrone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Immunohistochemical detection of NOD1 and NOD2 in the healthy murine and canine eye

(2009) Emma Scurrell et al.   VETERINARY OPHTHALMOLOGY

Microglial Activation in Human Diabetic Retinopathy

(2008) Hui-yang Zeng   ARCHIVES OF OPHTHALMOLOGY

Projection of Diabetic Retinopathy and Other Major Eye Diseases Among People With Diabetes Mellitus

(2008) Jinan B. Saaddine   ARCHIVES OF OPHTHALMOLOGY

Maternal depletion of NLRP5 blocks early embryogenesis in rhesus macaque monkeys (Macaca mulatta)

(2008) X. Wu   HUMAN REPRODUCTION

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

(2008) Antero Salminen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Identification of oocyte-selectiveNLRPgenes in rhesus macaque monkeys (Macaca mulatta)

(2008) Patrick McDaniel et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Association of Vitreous Inflammatory Factors with Diabetic Macular Edema

(2008) Hideharu Funatsu et al.   OPHTHALMOLOGY

Expression Analysis of the NLRP Gene Family Suggests a Role in Human Preimplantation Development

(2008) Pu Zhang et al.   PLoS One

Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice

(2007) Hideo Goto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS