Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

Thioredoxin-Interacting Protein Expression Is Required for VEGF-Mediated Angiogenic Signal in Endothelial Cells

(2013) Mohammed A. Abdelsaid et al.   ANTIOXIDANTS & REDOX SIGNALING

PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype

(2013) Yoshihiro Wada et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy

(2012) Takhellambam S. Devi et al.   Experimental Diabetes Research

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

(2012) Kate Schroder et al.   IMMUNOBIOLOGY

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

(2012) Catherine Diane Savage et al.   Frontiers in Immunology

Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1

(2011) Katherine E. Trueblood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms

(2011) Oded N. Spindel et al.   ANTIOXIDANTS & REDOX SIGNALING

17β-estradiol prevents reduction of retinal phosphorylated 14-3-3 zeta protein levels following a neurotoxic insult

(2011) Natsuko Koseki et al.   BRAIN RESEARCH

Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity

(2011) Mohammed MH Al-Gayyar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotection in glaucoma: recent and future directions

(2011) Helen V Danesh-Meyer   CURRENT OPINION IN OPHTHALMOLOGY

Coactivation of NMDA Receptors by Glutamate and d-Serine Induces Dilation of Isolated Middle Cerebral Arteries

(2011) Jillian L LeMaistre et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Neurovascular Protective Effect of FeTPPs in N-Methyl-D-Aspartate Model

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Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury

(2010) T. K. Ali et al.   DIABETOLOGIA

Animal Research: Reporting In Vivo Experiments: The ARRIVE Guidelines

(2010) Carol Kilkenny et al.   JOURNAL OF GENE MEDICINE

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned

(2009) Neville N. Osborne   ACTA OPHTHALMOLOGICA

Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system xc − in mouse retinal Müller glial cells

(2009) Barbara Mysona et al.   CELL AND TISSUE RESEARCH

Oxidative stress upregulates the NMDA receptor on cerebrovascular endothelium

(2009) Christian Betzen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions

(2009) Lorena Perrone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cutting Edge: TNF-  Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

(2009) L. Franchi et al.   JOURNAL OF IMMUNOLOGY

A Novel Calpain Inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic Acid 5-Methoxy-3-oxapentyl Ester (SNJ-1945), Reduces Murine Retinal Cell Death In Vitro and In Vivo

(2009) M. Shimazawa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Edaravone, a Free Radical Scavenger, Protects against Retinal Damage in Vitro and in Vivo

(2009) Y. Inokuchi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Early Intervention of Tyrosine Nitration Prevents Vaso-Obliteration and Neovascularization in Ischemic Retinopathy

(2009) M. A. Abdelsaid et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cellular signaling and factors involved in Müller cell gliosis: Neuroprotective and detrimental effects

(2009) Andreas Bringmann et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo

(2008) Yoshimi Nakajima et al.   BRAIN RESEARCH

Neurodegenerative Diseases of the Retina and Potential for Protection and Recovery

(2008) K.-G. Schmidt et al.   Current Neuropharmacology

Peroxynitrite Mediates Retinal Neurodegeneration by Inhibiting Nerve Growth Factor Survival Signaling in Experimental and Human Diabetes

(2008) T. K. Ali et al.   DIABETES

Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma

(2008) Y Munemasa et al.   GENE THERAPY

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

(2008) S. T. Y. Hui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA