Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

Differential Effects of Dexamethasone and Doxycycline on Inflammation and MMP Production in Murine Alkali-Burned Corneas Associated with Dry Eye

(2016) Fang Bian et al.   Ocular Surface

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

(2016) Rossana G. Iannitti et al.   Nature Communications

Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice

(2016) Zhen Puyang et al.   Scientific Reports

Inflammasome Inhibition: Putting Out the Fire

(2015) Mihai G. Netea et al.   Cell Metabolism

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

(2015) Yun-Hee Youm et al.   NATURE MEDICINE

Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway

(2015) Xukai Wang et al.   Scientific Reports

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

Aspergillus fumigatus triggers innate immune response via NOD1 signaling in human corneal epithelial cells

(2014) Yuting Zhang et al.   EXPERIMENTAL EYE RESEARCH

HCV core and NS3 proteins mediate toll like receptor induced innate immune response in corneal epithelium

(2014) Ayilam Ramachandran Rajalakshmy et al.   EXPERIMENTAL EYE RESEARCH

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye

(2014) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

Acidosis Drives Damage-associated Molecular Pattern (DAMP)-induced Interleukin-1 Secretion via a Caspase-1-independent Pathway

(2013) Michelle E. Edye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells

(2013) Victoria E. McGilligan et al.   PLoS One

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

(2013) Amina A. Negash et al.   PLoS Pathogens

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

(2012) Shrikant R. Mulay et al.   JOURNAL OF CLINICAL INVESTIGATION

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

IL-17 disrupts corneal barrier following desiccating stress

(2009) C S De Paiva et al.   Mucosal Immunology

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA