Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy

(2016) Angèle Nalbandian et al.   INFLAMMATION

Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation

(2016) Michael J. Primiano et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease

(2016) Manuela Pennisi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

(2016) Isis Ludwig-Portugall et al.   KIDNEY INTERNATIONAL

Gout

(2016) Nicola Dalbeth et al.   LANCET

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

The NEK-sus of the NLRP3 inflammasome

(2016) Filip Van Hauwermeiren et al.   NATURE IMMUNOLOGY

Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light

(2016) Zizhong Hu et al.   Cell Death & Disease

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

(2015) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation

(2015) Jonathan L. Schmid-Burgk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

(2015) Hexin Shi et al.   NATURE IMMUNOLOGY

Role of Endothelial Dysfunction and Arterial Stiffness in the Development of Diabetic Retinopathy: Figure 1

(2014) Gerasimos Siasos et al.   DIABETES CARE

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology

(2013) Rojo A. Ratsimandresy et al.   Frontiers in Immunology

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

(Pro)renin receptor is associated with angiogenic activity in proliferative diabetic retinopathy

(2012) A. Kanda et al.   DIABETOLOGIA

NEK7 is essential for centriole duplication and centrosomal accumulation of pericentriolar material proteins in interphase cells

(2011) S. Kim et al.   JOURNAL OF CELL SCIENCE

The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes

(2011) Rebecca C. Coll et al.   PLoS One

The Inflammasome in Atherosclerosis and Type 2 Diabetes

(2011) S. L. Masters et al.   Science Translational Medicine

The Inflammasomes

(2010) Kate Schroder et al.   CELL

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose

(2009) Laura Toma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?

(2009) T M Curtis et al.   EYE

Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

(2009) Susannah D. Brydges et al.   IMMUNITY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Cellular responses to reactive oxygen species-induced DNA damage and aging

(2008) Catharina Bertram et al.   BIOLOGICAL CHEMISTRY