NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis

Retinal Photoreceptor Expresses Toll-Like Receptors (TLRs) and Elicits Innate Responses Following TLR Ligand and Bacterial Challenge

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Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

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Redundant and Cooperative Interactions between TLR5 and NLRC4 in Protective Lung Mucosal Immunity against Pseudomonas aeruginosa

(2014) Leslie Tolle et al.   Journal of Innate Immunity

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

NLRC4 and TLR5 Each Contribute to Host Defense in Respiratory Melioidosis

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The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Antimicrobial functions of inflammasomes

(2013) Kaiwen W Chen et al.   CURRENT OPINION IN MICROBIOLOGY

Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia

(2013) Taylor S. Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

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Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges

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NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

The Inflammasomes

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Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity

(2010) Je-In Youn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

Function of Nod-like receptors in microbial recognition and host defense

(2008) Luigi Franchi et al.   IMMUNOLOGICAL REVIEWS

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

Pseudomonas aeruginosa activates caspase 1 through Ipaf

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