Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production

Differential Accumulation of Secreted AβPP Metabolites in Ocular Fluids

(2017) Annamalai Prakasam et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammation and its role in age-related macular degeneration

(2016) Anu Kauppinen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

β-amyloid, microglia, and the inflammasome in Alzheimer’s disease

(2015) Maike Gold et al.   Seminars in Immunopathology

The Dry Form of Age-Related Macular Degeneration (AMD): The Current Concepts of Pathogenesis and Prospects for Treatment

(2015) Hanna Zając-Pytrus et al.   Advances in Clinical and Experimental Medicine

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells

(2014) Ruozhou Tom Liu et al.   EXPERIMENTAL EYE RESEARCH

Age-related macular degeneration-clinical review and genetics update

(2013) R Ratnapriya et al.   CLINICAL GENETICS

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

(2013) Kanchan Garai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease

(2013) B Parajuli et al.   Cell Death & Disease

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Sensing damage by the NLRP3 inflammasome

(2011) Jaklien C. Leemans et al.   IMMUNOLOGICAL REVIEWS

CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis

(2011) Julien Bruban et al.   NEUROBIOLOGY OF DISEASE

The Retinal Pigment Epithelium in Health and Disease

(2010) J. R. Sparrrow et al.   CURRENT MOLECULAR MEDICINE

Amyloid-β(1-42) alters structure and function of retinal pigmented epithelial cells

(2009) Julien Bruban et al.   AGING CELL

Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease

(2009) Seth L. Masters et al.   Annual Review of Immunology