Material approaches to active tissue mechanics

Substrate curvature affects the shape, orientation, and polarization of renal epithelial cells

(2018) Sun-Min Yu et al.   Acta Biomaterialia

A hybrid computational model for collective cell durotaxis

(2018) Jorge Escribano et al.   Biomechanics and Modeling in Mechanobiology

Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces

(2018) Ehsan Ban et al.   BIOPHYSICAL JOURNAL

Wnt signaling in development and tissue homeostasis

(2018) Zachary Steinhart et al.   DEVELOPMENT

Force-dependent binding of vinculin to α-catenin regulates cell–cell contact stability and collective cell behavior

(2018) Rima Seddiki et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of cell cycle progression by cell–cell and cell–matrix forces

(2018) Marina Uroz et al.   NATURE CELL BIOLOGY

Geometric constraints during epithelial jamming

(2018) Lior Atia et al.   Nature Physics

Physics of lumen growth

(2018) Sabyasachi Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flocking transitions in confluent tissues

(2018) Fabio Giavazzi et al.   Soft Matter

Control of Mechanotransduction by Molecular Clutch Dynamics

(2018) Alberto Elosegui-Artola et al.   TRENDS IN CELL BIOLOGY

Quantifying compressive forces between living cell layers and within tissues using elastic round microgels

(2018) Erfan Mohagheghian et al.   Nature Communications

Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation

(2018) Elisabeth E. Charrier et al.   Nature Communications

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

(2018) Nil Ege et al.   Cell Systems

Collective cell migration without proliferation: density determines cell velocity and wave velocity

(2018) Sham Tlili et al.   Royal Society Open Science

Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo

(2018) Elias H. Barriga et al.   NATURE

Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin

(2017) Begum Erdogan et al.   JOURNAL OF CELL BIOLOGY

Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

(2017) Youmna Attieh et al.   JOURNAL OF CELL BIOLOGY

Physical models of collective cell motility: from cell to tissue

(2017) B A Camley et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Forces directing germ-band extension in Drosophila embryos

(2017) Deqing Kong et al.   MECHANISMS OF DEVELOPMENT

Measuring mechanodynamics in an unsupported epithelial monolayer grown at an air–water interface

(2017) Corinne Gullekson et al.   MOLECULAR BIOLOGY OF THE CELL

Topological defects control collective dynamics in neural progenitor cell cultures

(2017) Kyogo Kawaguchi et al.   NATURE

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Topological defects in epithelia govern cell death and extrusion

(2017) Thuan Beng Saw et al.   NATURE

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

(2017) Anna Labernadie et al.   NATURE CELL BIOLOGY

Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification

(2017) Yekaterina A. Miroshnikova et al.   NATURE CELL BIOLOGY

Quantifying forces in cell biology

(2017) Pere Roca-Cusachs et al.   NATURE CELL BIOLOGY

Endocytic reawakening of motility in jammed epithelia

(2017) Chiara Malinverno et al.   NATURE MATERIALS

Mechanobiology of collective cell behaviours

(2017) Benoit Ladoux et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Persistence-Driven Durotaxis: Generic, Directed Motility in Rigidity Gradients

(2017) Elizaveta A. Novikova et al.   PHYSICAL REVIEW LETTERS

Liquid behavior of cross-linked actin bundles

(2017) Kimberly L. Weirich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels

(2017) William J. Hadden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape

(2017) Kevin C. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collective cell migration: a physics perspective

(2017) Vincent Hakim et al.   REPORTS ON PROGRESS IN PHYSICS

Hydrodynamic instabilities, waves and turbulence in spreading epithelia

(2017) C. Blanch-Mercader et al.   Soft Matter

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions

(2017) René Marc Mège et al.   Cold Spring Harbor Perspectives in Biology

Matrix degradability controls multicellularity of 3D cell migration

(2017) Britta Trappmann et al.   Nature Communications

Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity

(2017) Julie Salomon et al.   Nature Communications

Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy

(2017) Alexander X. Cartagena-Rivera et al.   Nature Communications

Fibronectin-guided migration of carcinoma collectives

(2017) Sandeep Gopal et al.   Nature Communications

Shifting the optimal stiffness for cell migration

(2017) Benjamin L. Bangasser et al.   Nature Communications

Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

(2017) M. E. Dolega et al.   Nature Communications

Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

(2017) Alexandros Glentis et al.   Nature Communications

Preferred cell alignment along concave microgrooves

(2017) Baoce Sun et al.   RSC Advances

Laminin Levels Regulate Tissue Migration and Anterior-Posterior Polarity during Egg Morphogenesis in Drosophila

(2017) María C. Díaz de la Loza et al.   Cell Reports

Calcium spikes, waves and oscillations in a large, patterned epithelial tissue

(2017) Ramya Balaji et al.   Scientific Reports

Challenging FRET-based E-Cadherin force measurements in Drosophila

(2017) Dominik Eder et al.   Scientific Reports

On the Quantification of Cellular Velocity Fields

(2016) Dhruv K. Vig et al.   BIOPHYSICAL JOURNAL

Inference of Internal Stress in a Cell Monolayer

(2016) Vincent Nier et al.   BIOPHYSICAL JOURNAL

Tumor Cell Invasion Can Be Blocked by Modulators of Collagen Fibril Alignment That Control Assembly of the Extracellular Matrix

(2016) Moran Grossman et al.   CANCER RESEARCH

Epithelial Cell Packing Induces Distinct Modes of Cell Extrusions

(2016) Leyla Kocgozlu et al.   CURRENT BIOLOGY

Measuring forces and stressesin situin living tissues

(2016) Kaoru Sugimura et al.   DEVELOPMENT

Collective epithelial cell sheet adhesion and migration on polyelectrolyte multilayers with uniform and gradients of compliance

(2016) Jessica S. Martinez et al.   EXPERIMENTAL CELL RESEARCH

How cells respond to environmental cues – insights from bio-functionalized substrates

(2016) Verena Ruprecht et al.   JOURNAL OF CELL SCIENCE

Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells

(2016) R.J. Marjoram et al.   METHODS

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

Extracellular matrix scaffolding guides lumen elongation by inducing anisotropic intercellular mechanical tension

(2016) Qiushi Li et al.   NATURE CELL BIOLOGY

Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells

(2016) Arnold Hayer et al.   NATURE CELL BIOLOGY

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

Mechanosensing is critical for axon growth in the developing brain

(2016) David E Koser et al.   NATURE NEUROSCIENCE

Topological defects in confined populations of spindle-shaped cells

(2016) Guillaume Duclos et al.   Nature Physics

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

(2016) Sungmin Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial self-healing is recapitulated by a 3D biomimetic E-cadherin junction

(2016) Daniel J. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular smooth muscle cell durotaxis depends on extracellular matrix composition

(2016) Christopher D. Hartman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collective cell durotaxis emerges from long-range intercellular force transmission

(2016) R. Sunyer et al.   SCIENCE

Confocal reference free traction force microscopy

(2016) Martin Bergert et al.   Nature Communications

Boundaries steer the contraction of active gels

(2016) Matthias Schuppler et al.   Nature Communications

Cellular forces and matrix assembly coordinate fibrous tissue repair

(2016) Mahmut Selman Sakar et al.   Nature Communications

3D Printing Variable Stiffness Foams Using Viscous Thread Instability

(2016) Jeffrey I. Lipton et al.   Scientific Reports

Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation

(2016) Maike Werner et al.   Advanced Science

The design of reversible hydrogels to capture extracellular matrix dynamics

(2016) Adrianne M. Rosales et al.   Nature Reviews Materials

Multiprotein Printing by Light-Induced Molecular Adsorption

(2015) Pierre-Olivier Strale et al.   ADVANCED MATERIALS

Creating stiffness gradient polyvinyl alcohol hydrogel using a simple gradual freezing–thawing method to investigate stem cell differentiation behaviors

(2015) Tae Ho Kim et al.   BIOMATERIALS

Kymographic Imaging of the Elastic Modulus of Epithelial Cells during the Onset of Migration

(2015) Esra Roan et al.   BIOPHYSICAL JOURNAL

Two Fundamental Mechanisms Govern the Stiffening of Cross-linked Networks

(2015) Goran Žagar et al.   BIOPHYSICAL JOURNAL

Regulation of epithelial cell organization by tuning cell–substrate adhesion

(2015) Andrea Ravasio et al.   Integrative Biology

Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

(2015) Nam-Gyun Kim et al.   JOURNAL OF CELL BIOLOGY

Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes

(2015) Carol Jurchenko et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure

(2015) María Elena Fernández-Sánchez et al.   NATURE

Local and tissue-scale forces drive oriented junction growth during tissue extension

(2015) Claudio Collinet et al.   NATURE CELL BIOLOGY

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

(2015) Tamal Das et al.   NATURE CELL BIOLOGY

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Hydraulic fracture during epithelial stretching

(2015) Laura Casares et al.   NATURE MATERIALS

Unjamming and cell shape in the asthmatic airway epithelium

(2015) Jin-Ah Park et al.   NATURE MATERIALS

Active gel physics

(2015) J. Prost et al.   Nature Physics

Active Tensile Modulus of an Epithelial Monolayer

(2015) Romaric Vincent et al.   PHYSICAL REVIEW LETTERS

Emergence and Persistence of Collective Cell Migration on Small Circular Micropatterns

(2015) Felix J. Segerer et al.   PHYSICAL REVIEW LETTERS

Architecture and migration of an epithelium on a cylindrical wire

(2015) Hannah G. Yevick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis

(2015) Tom P. J. Wyatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct laser manipulation reveals the mechanics of cell contacts in vivo

(2015) Kapil Bambardekar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress controls the mechanics of collagen networks

(2015) Albert James Licup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

Celebrating Soft Matter's 10th Anniversary: Cell division: a source of active stress in cellular monolayers

(2015) Amin Doostmohammadi et al.   Soft Matter

Gap geometry dictates epithelial closure efficiency

(2015) Andrea Ravasio et al.   Nature Communications

Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices

(2015) Nikolce Gjorevski et al.   Scientific Reports

Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophila pupal wing

(2015) Raphaël Etournay et al.   eLife

Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results

(2015) P. Van Liedekerke et al.   Computational Particle Mechanics

Microfluidic approaches for epithelial cell layer culture and characterisation

(2014) Roland Thuenauer et al.   ANALYST

Cell jamming: Collective invasion of mesenchymal tumor cells imposed by tissue confinement

(2014) Anna Haeger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Vertex Models of Epithelial Morphogenesis

(2014) Alexander G. Fletcher et al.   BIOPHYSICAL JOURNAL

Determinants of Fluidlike Behavior and Effective Viscosity in Cross-Linked Actin Networks

(2014) Taeyoon Kim et al.   BIOPHYSICAL JOURNAL

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

(2014) Danfeng Cai et al.   CELL

ECM stiffness regulates glial migration in Drosophila and mammalian glioma models

(2014) S. N. Kim et al.   DEVELOPMENT

Tissue cohesion and the mechanics of cell rearrangement

(2014) R. David et al.   DEVELOPMENT

Instabilities and topological defects in active nematics

(2014) Sumesh P. Thampi et al.   EPL

Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells

(2014) M. Reffay et al.   NATURE CELL BIOLOGY

Collective and individual migration following the epithelial–mesenchymal transition

(2014) Ian Y. Wong et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vorticity, defects and correlations in active turbulence

(2014) S. P. Thampi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Universal Area Distributions in the Monolayers of Confluent Mammalian Cells

(2014) Gary Wilk et al.   PHYSICAL REVIEW LETTERS

Nonautonomous contact guidance signaling during collective cell migration

(2014) Camila Londono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area

(2014) Stephanie Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy barriers and cell migration in densely packed tissues

(2014) Dapeng Bi et al.   Soft Matter

Emergence of collective modes and tri-dimensional structures from epithelial confinement

(2014) M. Deforet et al.   Nature Communications

Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring

(2014) Corina Ciobanasu et al.   Nature Communications

Long-range ordered vorticity patterns in living tissue induced by cell division

(2014) Ninna S. Rossen et al.   Nature Communications

Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation

(2014) Maureen Cetera et al.   Nature Communications

Mechano-Transduction: From Molecules to Tissues

(2014) Beth L. Pruitt et al.   PLOS BIOLOGY

Surface Patterning via Thiol-Yne Click Chemistry: An Extremely Fast and Versatile Approach to Superhydrophilic-Superhydrophobic Micropatterns

(2014) Wenqian Feng et al.   Advanced Materials Interfaces

Integrated Micro/Nanoengineered Functional Biomaterials for Cell Mechanics and Mechanobiology: A Materials Perspective

(2013) Yue Shao et al.   ADVANCED MATERIALS

Polarizing cytoskeletal tension to induce leader cell formation during collective cell migration

(2013) Sebastian Rausch et al.   Biointerphases

Thermal Memory in Self-Assembled Collagen Fibril Networks

(2013) Martijn de Wild et al.   BIOPHYSICAL JOURNAL

Determinants of Maximal Force Transmission in a Motor-Clutch Model of Cell Traction in a Compliant Microenvironment

(2013) Benjamin L. Bangasser et al.   BIOPHYSICAL JOURNAL

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

(2013) Ludovic G. Vincent et al.   Biotechnology Journal

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Comparative study of non-invasive force and stress inference methods in tissue

(2013) S. Ishihara et al.   EUROPEAN PHYSICAL JOURNAL E

Toward single cell traction microscopy within 3D collagen matrices

(2013) Matthew S. Hall et al.   EXPERIMENTAL CELL RESEARCH

Guidance of collective cell migration by substrate geometry

(2013) Kevin Doxzen et al.   Integrative Biology

The cytoplasm of living cells behaves as a poroelastic material

(2013) Emad Moeendarbary et al.   NATURE MATERIALS

Epithelial bridges maintain tissue integrity during collective cell migration

(2013) Sri Ram Krishna Vedula et al.   NATURE MATERIALS

Quantifying cell-generated mechanical forces within living embryonic tissues

(2013) Otger Campàs et al.   NATURE METHODS

Molecular motors robustly drive active gels to a critically connected state

(2013) José Alvarado et al.   Nature Physics

Monolayer Stress Microscopy: Limitations, Artifacts, and Accuracy of Recovered Intercellular Stresses

(2013) Dhananjay T. Tambe et al.   PLoS One

Patterning droplets with durotaxis

(2013) R. W. Style et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theory of epithelial sheet morphology in three dimensions

(2013) E. Hannezo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrodynamics of soft active matter

(2013) M. C. Marchetti et al.   REVIEWS OF MODERN PHYSICS

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

A continuum model of epithelial spreading

(2013) Michael H. Köpf et al.   Soft Matter

Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention

(2013) Livingston Van De Water et al.   Advances in Wound Care

Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior

(2012) Brooke N. Mason et al.   Acta Biomaterialia

Complex Stiffness Gradient Substrates for Studying Mechanotactic Cell Migration

(2012) Cheng-Hwa R. Kuo et al.   ADVANCED MATERIALS

Matrix composition regulates three-dimensional network formation by endothelial cells and mesenchymal stem cells in collagen/fibrin materials

(2012) Rameshwar R. Rao et al.   ANGIOGENESIS

Mechanical Properties of the Extracellular Matrix of the Aorta Studied by Enzymatic Treatments

(2012) Jan-Willem M. Beenakker et al.   BIOPHYSICAL JOURNAL

In vitro 3D human small intestinal villous model for drug permeability determination

(2012) Jiajie Yu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cell confinement controls centrosome positioning and lumen initiation during epithelial morphogenesis

(2012) Alejo E. Rodríguez-Fraticelli et al.   JOURNAL OF CELL BIOLOGY

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

(2012) Mei Rosa Ng et al.   JOURNAL OF CELL BIOLOGY

Mechanical state, material properties and continuous description of an epithelial tissue

(2012) I. Bonnet et al.   Journal of the Royal Society Interface

Collective cell migration: leadership, invasion and segregation

(2012) A. J. Kabla   Journal of the Royal Society Interface

Bayesian inference of force dynamics during morphogenesis

(2012) Shuji Ishihara et al.   JOURNAL OF THEORETICAL BIOLOGY

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

A simple route to functionalize polyacrylamide hydrogels for the independent tuning of mechanotransduction cues

(2012) Thomas Grevesse et al.   LAB ON A CHIP

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

(2012) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding

(2012) Eliana Marinari et al.   NATURE

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Automated velocity mapping of migrating cell populations (AVeMap)

(2012) Maxime Deforet et al.   NATURE METHODS

Mechanical waves during tissue expansion

(2012) Xavier Serra-Picamal et al.   Nature Physics

Extrinsic Curvature Effects on Nematic Shells

(2012) Gaetano Napoli et al.   PHYSICAL REVIEW LETTERS

Multi-Scale Modeling in Morphogenesis: A Critical Analysis of the Cellular Potts Model

(2012) Anja Voss-Böhme   PLoS One

Easy Fabrication of Thin Membranes with Through Holes. Application to Protein Patterning

(2012) Thomas Masters et al.   PLoS One

Fabrication of Hydrogels with Steep Stiffness Gradients for Studying Cell Mechanical Response

(2012) Raimon Sunyer et al.   PLoS One

Host epithelial geometry regulates breast cancer cell invasiveness

(2012) E. Boghaert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coherent angular motion in the establishment of multicellular architecture of glandular tissues

(2012) K. Tanner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

(2012) E. Anon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging modes of collective cell migration induced by geometrical constraints

(2012) S. R. K. Vedula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing the mechanics of cultured cell monolayers

(2012) A. R. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collective and single cell behavior in epithelial contact inhibition

(2012) A. Puliafito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Screening of rat mesenchymal stem cell behaviour on polydimethylsiloxane stiffness gradients

(2011) Peng-Yuan Wang et al.   Acta Biomaterialia

Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

(2011) Mario A. Shields et al.   BIOCHEMICAL JOURNAL

Switchable adhesive substrates: Revealing geometry dependence in collective cell behavior

(2011) Claudio G. Rolli et al.   BIOMATERIALS

Substrate Viscosity Enhances Correlation in Epithelial Sheet Movement

(2011) Michael Murrell et al.   BIOPHYSICAL JOURNAL

The MDCK variety pack: choosing the right strain

(2011) Joseph D Dukes et al.   BMC CELL BIOLOGY

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

(2011) Gregory F. Weber et al.   DEVELOPMENTAL CELL

Probing mechanical principles of focal contacts in cell-matrix adhesion with a coupled stochastic-elastic modelling framework

(2011) H. Gao et al.   Journal of the Royal Society Interface

Electrospun Fibrous Scaffolds Promote Breast Cancer Cell Alignment and Epithelial–Mesenchymal Transition

(2011) Sharmistha Saha et al.   LANGMUIR

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

(2011) Ryan G. Wylie et al.   NATURE MATERIALS

Structure formation in active networks

(2011) Simone Köhler et al.   NATURE MATERIALS

Instabilities of Monolayered Epithelia: Shape and Structure of Villi and Crypts

(2011) E. Hannezo et al.   PHYSICAL REVIEW LETTERS

Glass-like dynamics of collective cell migration

(2011) T. E. Angelini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-ECM traction force modulates endogenous tension at cell-cell contacts

(2011) V. Maruthamuthu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Polarized Epithelium Organized by  - and  -Catenin Predates Cadherin and Metazoan Origins

(2011) D. J. Dickinson et al.   SCIENCE

Global Tissue Revolutions in a Morphogenetic Movement Controlling Elongation

(2011) S. L. Haigo et al.   SCIENCE

Productive tension: force-sensing and homeostasis of cell–cell junctions

(2011) Guillermo A. Gomez et al.   TRENDS IN CELL BIOLOGY

Velocity Fields in a Collectively Migrating Epithelium

(2010) L. Petitjean et al.   BIOPHYSICAL JOURNAL

The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation

(2010) S. Bahri et al.   DEVELOPMENT

Micropatterning as a tool to decipher cell morphogenesis and functions

(2010) M. Thery   JOURNAL OF CELL SCIENCE

Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

Myosin II contributes to cell-scale actin network treadmilling through network disassembly

(2010) Cyrus A. Wilson et al.   NATURE

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Boundary crossing in epithelial wound healing

(2010) E. Fong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluidization of tissues by cell division and apoptosis

(2010) J. Ranft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coaction of intercellular adhesion and cortical tension specifies tissue surface tension

(2010) M. Lisa Manning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Nonlinear viscoelasticity of adherent cells is controlled by cytoskeletal tension

(2010) Philip Kollmannsberger et al.   Soft Matter

Lifetime and Strength of Periodic Bond Clusters between Elastic Media under Inclined Loading

(2009) Jin Qian et al.   BIOPHYSICAL JOURNAL

PEGDA hydrogels with patterned elasticity: Novel tools for the study of cell response to substrate rigidity

(2009) Stephanie Nemir et al.   BIOTECHNOLOGY AND BIOENGINEERING

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure

(2009) Jerome Solon et al.   CELL

Mechanics of the F-actin cytoskeleton

(2009) Jonathan Stricker et al.   JOURNAL OF BIOMECHANICS

Nonlinear Elasticity of Stiff Filament Networks: Strain Stiffening, Negative Normal Stress, and Filament Alignment in Fibrin Gels†

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Simple and rapid process for single cell micro-patterning

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Study of cellular behaviors on concave and convex microstructures fabricated from elastic PDMS membranes

(2009) Joong Yull Park et al.   LAB ON A CHIP

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

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(2009) Xavier Trepat et al.   Nature Physics

Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells

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Strain-Induced Alignment in Collagen Gels

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Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition

(2009) E. H. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An active biopolymer network controlled by molecular motors

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Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

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Spatially controlled hydrogel mechanics to modulate stem cell interactions

(2009) Ross A. Marklein et al.   Soft Matter

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

AFM indentation study of breast cancer cells

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Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

(2008) Soo-Hong Lee et al.   BIOMATERIALS

Characterization of type I collagen gels modified by glycation

(2008) Megan E. Francis-Sedlak et al.   BIOMATERIALS

Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis

(2008) Fernando Martín-Belmonte et al.   CURRENT BIOLOGY

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

(2008) Aron B. Jaffe et al.   JOURNAL OF CELL BIOLOGY

Photopolymerized diffusion-defined polyacrylamide gradient gels for on-chip protein sizing

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Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

(2008) Celeste M Nelson et al.   Nature Protocols

Softening of the actin cytoskeleton by inhibition of myosin II

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Dynamical theory of active cellular response to external stress

(2008) Rumi De et al.   PHYSICAL REVIEW E

Polymer Pen Lithography

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