Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions

Mechanosensing and Mechanotransduction at Cell–Cell Junctions

(2017) Alpha S. Yap et al.   Cold Spring Harbor Perspectives in Biology

Cis and Trans Cooperativity of E-Cadherin Mediates Adhesion in Biomimetic Lipid Droplets

(2016) Lea-Laetitia Pontani et al.   BIOPHYSICAL JOURNAL

Adherens Junction and E-Cadherin complex regulation by epithelial polarity

(2016) Peter Coopman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular clustering in the cell: from weak interactions to optimized functional architectures

(2016) Pierre Recouvreux et al.   CURRENT OPINION IN CELL BIOLOGY

Measuring forces and stressesin situin living tissues

(2016) Kaoru Sugimura et al.   DEVELOPMENT

Myosin-dependent remodeling of adherens junctions protects junctions from Snail-dependent disassembly

(2016) Mo Weng et al.   JOURNAL OF CELL BIOLOGY

Remodeling the zonula adherens in response to tension and the role of afadin in this response

(2016) Wangsun Choi et al.   JOURNAL OF CELL BIOLOGY

A phenomenological model of cell–cell adhesion mediated by cadherins

(2016) Simona Mancini et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Nanoscale architecture of cadherin-based cell adhesions

(2016) Cristina Bertocchi et al.   NATURE CELL BIOLOGY

Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism

(2016) Shota Kudo et al.   STRUCTURE

Front–Rear Polarization by Mechanical Cues: From Single Cells to Tissues

(2016) Benoit Ladoux et al.   TRENDS IN CELL BIOLOGY

25 Years of Tension over Actin Binding to the Cadherin Cell Adhesion Complex: The Devil is in the Details

(2016) W. James Nelson et al.   TRENDS IN CELL BIOLOGY

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

(2016) Zahra Erami et al.   Cell Reports

Mechano-adaptive sensory mechanism of α-catenin under tension

(2016) Koichiro Maki et al.   Scientific Reports

Dynamic Visualization of α-Catenin Reveals Rapid, Reversible Conformation Switching between Tension States

(2015) Tae-Jin Kim et al.   CURRENT BIOLOGY

Jack of all trades: functional modularity in the adherens junction

(2015) Anup Padmanabhan et al.   CURRENT OPINION IN CELL BIOLOGY

Actin-Delimited Adhesion-Independent Clustering of E-Cadherin Forms the Nanoscale Building Blocks of Adherens Junctions

(2015) Yao Wu et al.   DEVELOPMENTAL CELL

A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and β-Catenin In Vitro and In Vivo

(2015) Hee-Jung Choi et al.   DEVELOPMENTAL CELL

Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo

(2015) Chaminda R. Samarage et al.   DEVELOPMENTAL CELL

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

(2015) Alpha S. Yap et al.   DEVELOPMENTAL CELL

The mechanotransduction machinery at work at adherens junctions

(2015) B. Ladoux et al.   Integrative Biology

The formation of ordered nanoclusters controls cadherin anchoring to actin and cell–cell contact fluidity

(2015) Pierre-Olivier Strale et al.   JOURNAL OF CELL BIOLOGY

α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

(2015) Chi-Shuo Chen et al.   JOURNAL OF CELL BIOLOGY

 -Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism

(2015) D. J. Escobar et al.   JOURNAL OF CELL SCIENCE

Control of cell–cell forces and collective cell dynamics by the intercellular adhesome

(2015) Elsa Bazellières et al.   NATURE CELL BIOLOGY

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

(2015) Rashmi Priya et al.   NATURE CELL BIOLOGY

LPP inhibits collective cell migration during lung cancer dissemination

(2015) S Kuriyama et al.   ONCOGENE

Mechanosensitive Adaptation of E-Cadherin Turnover across adherens Junctions

(2015) Simon de Beco et al.   PLoS One

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

(2014) Danfeng Cai et al.   CELL

Tension-Sensitive Actin Assembly Supports Contractility at the Epithelial Zonula Adherens

(2014) Joanne M. Leerberg et al.   CURRENT BIOLOGY

Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton

(2014) R. B. Troyanovsky et al.   JOURNAL OF CELL SCIENCE

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The minimal cadherin-catenin complex binds to actin filaments under force

(2014) C. D. Buckley et al.   SCIENCE

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

(2014) Z. Guo et al.   Science Signaling

Force-dependent conformational switch of α-catenin controls vinculin binding

(2014) Mingxi Yao et al.   Nature Communications

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

(2014) Mingxi Yao et al.   Scientific Reports

Mapping the dynamics of force transduction at cell–cell junctions of epithelial clusters

(2014) Mei Rosa Ng et al.   eLife

Theory and Simulations of Adhesion Receptor Dimerization on Membrane Surfaces

(2013) Yinghao Wu et al.   BIOPHYSICAL JOURNAL

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Principles of E-Cadherin Supramolecular Organization In Vivo

(2013) Binh-An Truong Quang et al.   CURRENT BIOLOGY

NMII Forms a Contractile Transcellular Sarcomeric Network to Regulate Apical Cell Junctions and Tissue Geometry

(2013) Seham Ebrahim et al.   CURRENT BIOLOGY

Guidance of collective cell migration by substrate geometry

(2013) Kevin Doxzen et al.   Integrative Biology

An Autoinhibited Structure of α-Catenin and Its Implications for Vinculin Recruitment to Adherens Junctions

(2013) Noboru Ishiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding to F-actin guides cadherin cluster assembly, stability, and movement

(2013) Soonjin Hong et al.   JOURNAL OF CELL BIOLOGY

ZO-1 recruitment to  -catenin - a novel mechanism for coupling the assembly of tight junctions to adherens junctions

(2013) J. L. Maiers et al.   JOURNAL OF CELL SCIENCE

Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell–cell and cell–substrate adhesion

(2013) Christina M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1

(2013) L. S. Rodgers et al.   JOURNAL OF CELL SCIENCE

αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors

(2013) Scott D. Hansen et al.   MOLECULAR BIOLOGY OF THE CELL

Dimer asymmetry defines α-catenin interactions

(2013) Erumbi S Rangarajan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanics of Epithelial Tissue Homeostasis and Morphogenesis

(2013) C. Guillot et al.   SCIENCE

α-Catenin and Vinculin Cooperate to Promote High E-cadherin-based Adhesion Strength

(2012) William A. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cytoskeletal Protein α-Catenin Unfurls upon Binding to Vinculin

(2012) Erumbi S. Rangarajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

(2012) Aparna Ratheesh et al.   NATURE CELL BIOLOGY

Nucleation of Ligand-Receptor Domains in Membrane Adhesion

(2012) Timo Bihr et al.   PHYSICAL REVIEW LETTERS

Emerging modes of collective cell migration induced by geometrical constraints

(2012) S. R. K. Vedula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 E-catenin is an autoinhibited molecule that coactivates vinculin

(2012) H.-J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch

(2012) N. Borghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

(2011) Alan S. Fanning et al.   MOLECULAR BIOLOGY OF THE CELL

The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins

(2011) Oliver J. Harrison et al.   STRUCTURE

Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion

(2010) Noboru Ishiyama et al.   CELL

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

Vinculin regulates cell-surface E-cadherin expression by binding to  -catenin

(2010) X. Peng et al.   JOURNAL OF CELL SCIENCE

Planar polarized actomyosin contractile flows control epithelial junction remodelling

(2010) Matteo Rauzi et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Mechanical tugging force regulates the size of cell-cell junctions

(2010) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TheDrosophilaafadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

(2009) Jessica K. Sawyer et al.   JOURNAL OF CELL BIOLOGY

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

A two-tiered mechanism for stabilization and immobilization of E-cadherin

(2008) Matthieu Cavey et al.   NATURE

Crystallographic Conformers of Actin in a Biologically Active Bundle of Filaments

(2007) Yao Cong et al.   JOURNAL OF MOLECULAR BIOLOGY