Topological defects in epithelia govern cell death and extrusion

Inference of Internal Stress in a Cell Monolayer

(2016) Vincent Nier et al.   BIOPHYSICAL JOURNAL

Tissue Crowding Induces Caspase-Dependent Competition for Space

(2016) Romain Levayer et al.   CURRENT BIOLOGY

Epithelial Cell Packing Induces Distinct Modes of Cell Extrusions

(2016) Leyla Kocgozlu et al.   CURRENT BIOLOGY

Topological defects in confined populations of spindle-shaped cells

(2016) Guillaume Duclos et al.   Nature Physics

Defect-Mediated Morphologies in Growing Cell Colonies

(2016) Amin Doostmohammadi et al.   PHYSICAL REVIEW LETTERS

Mechanical cell competition kills cells via induction of lethal p53 levels

(2016) Laura Wagstaff et al.   Nature Communications

Stabilization of active matter by flow-vortex lattices and defect ordering

(2016) Amin Doostmohammadi et al.   Nature Communications

MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status

(2016) Takanori Chiba et al.   Scientific Reports

Active gel physics

(2015) J. Prost et al.   Nature Physics

Celebrating Soft Matter's 10th Anniversary: Cell division: a source of active stress in cellular monolayers

(2015) Amin Doostmohammadi et al.   Soft Matter

Border Forces and Friction Control Epithelial Closure Dynamics

(2014) Olivier Cochet-Escartin et al.   BIOPHYSICAL JOURNAL

FogBank: a single cell segmentation across multiple cell lines and image modalities

(2014) Joe Chalfoun et al.   BMC BIOINFORMATICS

Instabilities and topological defects in active nematics

(2014) Sumesh P. Thampi et al.   EPL

Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours

(2014) D. Kuipers et al.   JOURNAL OF CELL SCIENCE

Forces driving epithelial wound healing

(2014) Agustí Brugués et al.   Nature Physics

Vorticity, defects and correlations in active turbulence

(2014) S. P. Thampi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Biphasic, Lyotropic, Active Nematics

(2014) Matthew L. Blow et al.   PHYSICAL REVIEW LETTERS

Long-range ordered vorticity patterns in living tissue induced by cell division

(2014) Ninna S. Rossen et al.   Nature Communications

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

New development in freefem++

(2013) F. Hecht   Journal of Numerical Mathematics

Epithelial bridges maintain tissue integrity during collective cell migration

(2013) Sri Ram Krishna Vedula et al.   NATURE MATERIALS

Quantifying cell-generated mechanical forces within living embryonic tissues

(2013) Otger Campàs et al.   NATURE METHODS

Mechanical Control of Cell flow in Multicellular Spheroids

(2013) Morgan Delarue et al.   PHYSICAL REVIEW LETTERS

Monolayer Stress Microscopy: Limitations, Artifacts, and Accuracy of Recovered Intercellular Stresses

(2013) Dhananjay T. Tambe et al.   PLoS One

Morphology transition in lipid vesicles due to in-plane order and topological defects

(2013) Linda S. Hirst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topological defects and density fluctuations in collectively moving systems

(2013) V. Schaller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular stresses in patterned cell assemblies

(2013) Michel Moussus et al.   Soft Matter

Spontaneous motion in hierarchically assembled active matter

(2012) Tim Sanchez et al.   NATURE

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding

(2012) Eliana Marinari et al.   NATURE

Emerging modes of collective cell migration induced by geometrical constraints

(2012) S. R. K. Vedula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing the mechanics of cultured cell monolayers

(2012) A. R. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluid Mechanics of Planktonic Microorganisms

(2011) Jeffrey S. Guasto et al.   Annual Review of Fluid Mechanics

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

(2011) R. Rezakhaniha et al.   Biomechanics and Modeling in Mechanobiology

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Nonlinear dynamics and rheology of active fluids: Simulations in two dimensions

(2011) S. M. Fielding et al.   PHYSICAL REVIEW E

Excitable Patterns in Active Nematics

(2011) L. Giomi et al.   PHYSICAL REVIEW LETTERS

Undulation Instability of Epithelial Tissues

(2011) Markus Basan et al.   PHYSICAL REVIEW LETTERS

Fluid dynamics and noise in bacterial cell-cell and cell-surface scattering

(2011) K. Drescher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bayesian inference in physics

(2011) Udo von Toussaint   REVIEWS OF MODERN PHYSICS

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Spontaneous flow states in active nematics: A unified picture

(2009) S. A. Edwards et al.   EPL

Quantification of growth asymmetries in developing epithelia

(2009) T. Bittig et al.   EUROPEAN PHYSICAL JOURNAL E

Characterization of the interface between normal and transformed epithelial cells

(2009) Catherine Hogan et al.   NATURE CELL BIOLOGY

Dynamics of anisotropic tissue growth

(2008) Thomas Bittig et al.   NEW JOURNAL OF PHYSICS

Biomechanical ordering of dense cell populations

(2008) D. Volfson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptotic Force and Tissue Dynamics During Drosophila Embryogenesis

(2008) Y. Toyama et al.   SCIENCE