Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

Rho GTPase and Shroom direct planar polarized actomyosin contractility during convergent extension

(2014) Sérgio de Matos Simões et al.   JOURNAL OF CELL BIOLOGY

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

Principles of E-Cadherin Supramolecular Organization In Vivo

(2013) Binh-An Truong Quang et al.   CURRENT BIOLOGY

ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation

(2013) Cathrin Herder et al.   DEVELOPMENT

Pou5f1-Dependent EGF Expression Controls E-Cadherin Endocytosis, Cell Adhesion, and Zebrafish Epiboly Movements

(2013) Sungmin Song et al.   DEVELOPMENTAL CELL

Distinct Rap1 Activity States Control the Extent of Epithelial Invagination via α-Catenin

(2013) Yu-Chiun Wang et al.   DEVELOPMENTAL CELL

Integration of Left-Right Pitx2 Transcription and Wnt Signaling Drives Asymmetric Gut Morphogenesis via Daam2

(2013) Ian C. Welsh et al.   DEVELOPMENTAL CELL

Oscillation and Polarity of E-Cadherin Asymmetries Control Actomyosin Flow Patterns during Morphogenesis

(2013) Romain Levayer et al.   DEVELOPMENTAL CELL

An Autoinhibited Structure of α-Catenin and Its Implications for Vinculin Recruitment to Adherens Junctions

(2013) Noboru Ishiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding between the Junctional Proteins Afadin and PLEKHA7 and Implication in the Formation of Adherens Junction in Epithelial Cells

(2013) Souichi Kurita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of p190RhoGAP with C-terminal Domain of p120-catenin Modulates Endothelial Cytoskeleton and Permeability

(2013) Noureddine Zebda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

(2013) Koji Ando et al.   JOURNAL OF CELL BIOLOGY

TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function

(2013) S. P. Ngok et al.   JOURNAL OF CELL SCIENCE

Cycling around cell-cell adhesion with Rho GTPase regulators

(2013) J. McCormack et al.   JOURNAL OF CELL SCIENCE

αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors

(2013) Scott D. Hansen et al.   MOLECULAR BIOLOGY OF THE CELL

Monomeric α-catenin links cadherin to the actin cytoskeleton

(2013) Ridhdhi Desai et al.   NATURE CELL BIOLOGY

Apical domain polarization localizes actin–myosin activity to drive ratchet-like apical constriction

(2013) Frank M. Mason et al.   NATURE CELL BIOLOGY

Cell intercalation from top to bottom

(2013) Elise Walck-Shannon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dimer asymmetry defines α-catenin interactions

(2013) Erumbi S Rangarajan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure

(2013) Chih-Wen Chu et al.   PLoS One

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans

(2012) Allison M. Lynch et al.   CURRENT BIOLOGY

Shroom3 is required downstream of FGF signalling to mediate proneuromast assembly in zebrafish

(2012) S. Ernst et al.   DEVELOPMENT

Abl Regulates Planar Polarized Junctional Dynamics through β-Catenin Tyrosine Phosphorylation

(2012) Masako Tamada et al.   DEVELOPMENTAL CELL

The Cytoskeletal Protein α-Catenin Unfurls upon Binding to Vinculin

(2012) Erumbi S. Rangarajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p120-catenin binding masks an endocytic signal conserved in classical cadherins

(2012) Benjamin A. Nanes et al.   JOURNAL OF CELL BIOLOGY

α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction

(2012) Vivian W. Tang et al.   JOURNAL OF CELL BIOLOGY

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

The PDZ-GEF protein Dizzy regulates the establishment of adherens junctions required for ventral furrow formation in Drosophila

(2012) P. Spahn et al.   JOURNAL OF CELL SCIENCE

DLC1 Interaction with  -Catenin Stabilizes Adherens Junctions and Enhances DLC1 Antioncogenic Activity

(2012) V. Tripathi et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

(2012) Swarna Mohan et al.   MOLECULAR BIOLOGY OF THE CELL

A WAVE2–Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

(2012) Suzie Verma et al.   MOLECULAR BIOLOGY OF THE CELL

Differential positioning of adherens junctions is associated with initiation of epithelial folding

(2012) Yu-Chiun Wang et al.   NATURE

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

(2012) Aparna Ratheesh et al.   NATURE CELL BIOLOGY

Cadherins in Brain Morphogenesis and Wiring

(2012) Shinji Hirano et al.   PHYSIOLOGICAL REVIEWS

 E-catenin is an autoinhibited molecule that coactivates vinculin

(2012) H.-J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions

(2012) Minna Roh-Johnson et al.   SCIENCE

Thinking outside the cell: how cadherins drive adhesion

(2012) Julia Brasch et al.   TRENDS IN CELL BIOLOGY

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation

(2012) F. Twiss et al.   Biology Open

The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity

(2012) G Holeiter et al.   Oncogenesis

A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination

(2011) T. F. Plageman et al.   DEVELOPMENT

Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

(2011) Timothy F. Plageman et al.   DEVELOPMENTAL BIOLOGY

Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity

(2011) Ryan S. Gray et al.   DEVELOPMENTAL CELL

Epithelial Protein Lost In Neoplasm (EPLIN) Interacts with α-Catenin and Actin Filaments in Endothelial Cells and Stabilizes Vascular Capillary Networkin Vitro

(2011) Adeline Chervin-Pétinot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional diversity of cadherin at the adherens junction

(2011) Hiroki Oda et al.   JOURNAL OF CELL BIOLOGY

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

(2011) Buzz Baum et al.   JOURNAL OF CELL BIOLOGY

Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF

(2011) Hiroyuki Nakajima et al.   JOURNAL OF CELL BIOLOGY

Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping

(2011) Katsutoshi Taguchi et al.   JOURNAL OF CELL BIOLOGY

A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension

(2011) Jessica K. Sawyer et al.   MOLECULAR BIOLOGY OF THE CELL

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

(2011) Alan S. Fanning et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of small GTPases at epithelial cell-cell junctions

(2011) Sandra Citi et al.   MOLECULAR MEMBRANE BIOLOGY

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway

(2011) Eva M. Kovacs et al.   NATURE CELL BIOLOGY

Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation

(2011) Takashi Ishiuchi et al.   NATURE CELL BIOLOGY

Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis

(2011) Romain Levayer et al.   NATURE CELL BIOLOGY

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

(2011) Stephen J. Terry et al.   NATURE CELL BIOLOGY

Chirality in Planar Cell Shape Contributes to Left-Right Asymmetric Epithelial Morphogenesis

(2011) Kiichiro Taniguchi et al.   SCIENCE

The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins

(2011) Oliver J. Harrison et al.   STRUCTURE

Adherens junctions connect stress fibers between adjacent endothelial cells

(2010) Jaime Millan et al.   BMC BIOLOGY

Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion

(2010) Noboru Ishiyama et al.   CELL

Movement Directionality in Collective Migration of Germ Layer Progenitors

(2010) Yohanna Arboleda-Estudillo et al.   CURRENT BIOLOGY

Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

(2010) T. F. Plageman et al.   DEVELOPMENT

Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut

(2010) M.-I Chung et al.   DEVELOPMENT

The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila

(2010) D. J. V. David et al.   DEVELOPMENT

Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure

(2010) G. B. Blanchard et al.   DEVELOPMENT

Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

(2010) Sérgio de Matos Simões et al.   DEVELOPMENTAL CELL

Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction

(2010) Cory Bolinger et al.   DEVELOPMENTAL DYNAMICS

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

Vinculin regulates cell-surface E-cadherin expression by binding to  -catenin

(2010) X. Peng et al.   JOURNAL OF CELL SCIENCE

Planar polarized actomyosin contractile flows control epithelial junction remodelling

(2010) Matteo Rauzi et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

In vitro and in vivo reconstitution of the cadherin-catenin-actin complex from Caenorhabditis elegans

(2010) A. V. Kwiatkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure

(2009) Jerome Solon et al.   CELL

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia

(2009) Stephen J. Warner et al.   JOURNAL OF CELL BIOLOGY

TheDrosophilaafadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

(2009) Jessica K. Sawyer et al.   JOURNAL OF CELL BIOLOGY

03-P050 The role of Bazooka/Par3 in epithelial intercalation – A live imaging approach

(2009) Sergio Simoes et al.   MECHANISMS OF DEVELOPMENT

Rearrangements of the Actin Cytoskeleton and E-Cadherin–Based Adherens Junctions Caused by Neoplasic Transformation Change Cell–Cell Interactions

(2009) Dmitry V. Ayollo et al.   PLoS One

Endocytosis is required for E-cadherin redistribution at mature adherens junctions

(2009) S. de Beco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells

(2009) Gemma Bellett et al.   CELL MOTILITY AND THE CYTOSKELETON

Anchorage of Microtubule Minus Ends to Adherens Junctions Regulates Epithelial Cell-Cell Contacts

(2008) Wenxiang Meng et al.   CELL

The RapGEF PDZ-GEF2 is required for maturation of cell–cell junctions

(2008) Nadia Dubé et al.   CELLULAR SIGNALLING

Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability

(2008) Marios Georgiou et al.   CURRENT BIOLOGY

Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis

(2008) C. C. F. Homem et al.   DEVELOPMENT

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT

The Chirality of Gut Rotation Derives from Left-Right Asymmetric Changes in the Architecture of the Dorsal Mesentery

(2008) Nicole M. Davis et al.   DEVELOPMENTAL CELL

Apical Accumulation of Rho in the Neural Plate Is Important for Neural Plate Cell Shape Change and Neural Tube Formation

(2008) Nagatoki Kinoshita et al.   MOLECULAR BIOLOGY OF THE CELL

Pulsed contractions of an actin–myosin network drive apical constriction

(2008) Adam C. Martin et al.   NATURE

The direction of gut looping is established by changes in the extracellular matrix and in cell:cell adhesion

(2008) N. A. Kurpios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Cadherin Trafficking

(2008) Emmanuella Delva et al.   TRAFFIC