Mechanical memory and dosing influence stem cell fate

Mechanobiology of bone marrow stem cells: From myosin-II forces to compliance of matrix and nucleus in cell forms and fates

(2013) Jae-Won Shin et al.   DIFFERENTIATION

Modeling controlled photodegradation in optically thick hydrogels

(2013) Mark W. Tibbitt et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Mechanical Properties and Degradation of Chain and Step-Polymerized Photodegradable Hydrogels

(2013) Mark W. Tibbitt et al.   MACROMOLECULES

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway

(2013) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus

(2012) Huan Wang et al.   PLoS One

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

(2012) Murat Guvendiren et al.   Nature Communications

Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds

(2011) Peter D. Mariner et al.   Journal of Tissue Engineering and Regenerative Medicine

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

(2011) Rebecca J. McMurray et al.   NATURE MATERIALS

Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

(2010) John M. Maloney et al.   BIOPHYSICAL JOURNAL

Photodegradable Hydrogels to Generate Positive and Negative Features over Multiple Length Scales

(2010) Darice Y. Wong et al.   MACROMOLECULES

Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms

(2010) April M Kloxin et al.   Nature Protocols

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materials

(2010) Mark W. Tibbitt et al.   Soft Matter

Tunable Hydrogels for External Manipulation of Cellular Microenvironments through Controlled Photodegradation

(2009) April M. Kloxin et al.   ADVANCED MATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix

(2009) Farshid Guilak et al.   Cell Stem Cell

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

A photo-modulatable material for probing cellular responses to substrate rigidity

(2009) Margo T. Frey et al.   Soft Matter