Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation
出版年份 2021 全文链接
标题
Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation
作者
关键词
-
出版物
CHEMICAL REVIEWS
Volume 122, Issue 1, Pages 269-339
出版商
American Chemical Society (ACS)
发表日期
2021-10-22
DOI
10.1021/acs.chemrev.1c00496
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis
- (2020) Albert Cabré et al. ACCOUNTS OF CHEMICAL RESEARCH
- Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates
- (2020) Yawen Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines
- (2020) Aaron Trowbridge et al. CHEMICAL REVIEWS
- P-Stereogenic N-Phosphine-Phosphite Ligands for the Rh-Catalyzed Hydrogenation of Olefins
- (2020) Maria Biosca et al. JOURNAL OF ORGANIC CHEMISTRY
- Cobalt-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Carboxylic Acids by Homolytic H2 Cleavage
- (2020) Hongyu Zhong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Development of a Convergent, Kilogram Scale Synthesis of an Antibacterial Clinical Candidate using an Enantioselective Hydrogenation
- (2020) Helen Benson et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Enantioselective Synthesis of a 2,3-Benzodiazepine Intermediate of BET Inhibitor BAY 1238097 via Catalytic Asymmetric Hydrogenation
- (2020) Gerard K. M. Verzijl et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Application of Crabtree/Pfaltz-Type Iridium Complexes for the Catalyzed Asymmetric Hydrogenation of an Agrochemical Building Block
- (2020) Jacob Schneekönig et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- The combination of asymmetric hydrogenation of olefins and direct reductive amination
- (2020) Shuai Yuan et al. Nature Communications
- Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines
- (2020) Alexia N. Kim et al. ACS Catalysis
- Asymmetric Hydrogenation of α-Boryl Enamides Enabled by Nonbonding Interactions
- (2020) Dongyang Fan et al. ACS Catalysis
- Highly Enantioselective Synthesis of Sitagliptin
- (2020) Kishor V. Khopade et al. Asian Journal of Organic Chemistry
- Diaza-Crown Ether-Bridged Chiral Diphosphoramidite Ligands: Synthesis and Applications in Asymmetric Catalysis
- (2020) Yier Luo et al. JOURNAL OF ORGANIC CHEMISTRY
- Correction to “Application of Crabtree/Pfaltz-type Iridium Complexes for the Catalyzed Asymmetric Hydrogenation of an Agrochemical Building Block”
- (2020) Jacob Schneekönig et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Enantioselective Total Syntheses of (−)‐20‐ epi ‐Vincamine and (−)‐20‐ epi ‐Eburnamonine by Ir‐Catalyzed Asymmetric Imine Hydrogenation/Lactamization Cascade
- (2020) Wen Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Iridium‐Catalyzed Enantioselective Hydrogenation of Indole and Benzofuran Derivatives
- (2020) Yao Ge et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation of Cationic Intermediates for the Synthesis of Chiral N , O ‐Acetals
- (2020) Yongjie Sun et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Ruthenium-Catalyzed Hydrogenation of Terpyridine-Type N-Heteroarenes: Direct Access to Chiral Tridentate Nitrogen Ligands
- (2020) Chenghao Li et al. ORGANIC LETTERS
- Iridium-catalyzed acid-assisted asymmetric hydrogenation of oximes to hydroxylamines
- (2020) Josep Mas-Roselló et al. SCIENCE
- Noncovalent Interaction-Assisted Ferrocenyl Phosphine Ligands in Asymmetric Catalysis
- (2020) Qingyang Zhao et al. ACCOUNTS OF CHEMICAL RESEARCH
- Transition-Metal-Catalyzed Reductive Amination Employing Hydrogen
- (2020) Torsten Irrgang et al. CHEMICAL REVIEWS
- P-Chirogenic Diphosphazanes with Axially Chiral Substituents and Their Use in Rh-Catalyzed Asymmetric Hydrogenation
- (2020) Jan-Ole Moritz et al. JOURNAL OF ORGANIC CHEMISTRY
- Ruthenium-Catalyzed Enantioselective Hydrogenation of Hydrazones
- (2020) Christopher H. Schuster et al. ORGANIC LETTERS
- Recent Developments in Transition-Metal-Catalyzed Asymmetric Hydrogenation of Enamides
- (2020) Phannarath Phansavath et al. SYNTHESIS-STUTTGART
- Efficient Access to Chiral 2-Oxazolidinones via Ni-Catalyzed Asymmetric Hydrogenation: Scope Study, Mechanistic Explanation, and Origin of Enantioselectivity
- (2020) Yuanhua Liu et al. ACS Catalysis
- Manganese‐Catalyzed Asymmetric Hydrogenation of Quinolines Enabled by π–π Interaction**
- (2020) Chenguang Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iridium-Catalyzed Asymmetric Hydrogenation of Sterically Hindered Cyclic Imines for Enantioselective Synthesis of Tetrahydroisoquinolines
- (2020) Bin Li et al. ORGANIC LETTERS
- Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines
- (2020) Dan Liu et al. Nature Communications
- Metal-Catalyzed Asymmetric Hydrogenation of C═N Bonds
- (2020) Racha Abed Ali Abdine et al. ACS Catalysis
- Synthesis of Chiral α-Aminosilanes through Palladium-Catalyzed Asymmetric Hydrogenation of Silylimines
- (2019) Dongyang Fan et al. ORGANIC LETTERS
- Phosphite-thioether/selenoether ligands from carbohydrates: An easily accessible ligand library for the asymmetric hydrogenation of functionalized and unfunctionalized olefins
- (2019) Montserrat Diéguez et al. ChemCatChem
- Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines
- (2019) Bowen Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selective Arene Hydrogenation Provides Direct Access to Saturated Carbo- and Heterocycles
- (2019) Mario Patrick Wiesenfeldt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective Access to Chiral Cyclic Sulfamidates Through Iridium-Catalyzed Asymmetric Hydrogenation
- (2019) Yuanhua Liu et al. ADVANCED SYNTHESIS & CATALYSIS
- Syntheses and Catalytic Hydrogenation Performance of Cationic Bis(phosphine) Cobalt(I) Diene and Arene Compounds
- (2019) Hongyu Zhong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ir-Catalyzed Double Asymmetric Hydrogenation of 3,6-Dialkylidene-2,5-diketopiperazines for Enantioselective Synthesis of Cyclic Dipeptides
- (2019) Yao Ge et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Total Synthesis of Conulothiazole A
- (2019) Antoine Nitelet et al. ORGANIC LETTERS
- A Synthetic Route to Chiral Benzo-Fused N-Heterocycles via Sequential Intramolecular Hydroamination and Asymmetric Hydrogenation of Anilino-Alkynes
- (2019) Cong Xu et al. ORGANOMETALLICS
- Iridium complexes with P-stereogenic phosphino imidazole ligands: Synthesis, structure and catalysis
- (2019) Rubén Álvarez-Yebra et al. TETRAHEDRON
- Enantioselective Synthesis of β‐Methyl Amines via Iridium‐Catalyzed Asymmetric Hydrogenation of N‐Sulfonyl Allyl Amines
- (2019) Albert Cabré et al. ADVANCED SYNTHESIS & CATALYSIS
- Stereoelectronic Effect in Ligand Design: Enantioselective Rh-Catalyzed Hydrogenation of Alkyl Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib
- (2019) Wenjun Tang ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemo- and Enantioselective Hydrogenation of α-Formyl Enamides: An Efficient Access to Chiral α-Amido Aldehydes
- (2019) Jian Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Chiral β-Fluoroalkyl β-Amino Acid Derivatives via Palladium-Catalyzed Hydrogenation
- (2019) Mu-Wang Chen et al. JOURNAL OF ORGANIC CHEMISTRY
- Asymmetric Hydrogenation of Dibenzo[c,e]azepine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts
- (2019) Shanshan Zhang et al. ORGANIC LETTERS
- Ir‐catalyzed Asymmetric Hydrogenation of α‐Imino Esters with Chiral Ferrocenylphosphine‐Phosphoramidite Ligands
- (2019) Xin‐Hu Hu et al. ADVANCED SYNTHESIS & CATALYSIS
- Enantioselective Hydrogenation of Activated Aryl Imines Catalyzed by an Iron(II) P-NH-P′ Complex
- (2019) Chris S. G. Seo et al. JOURNAL OF ORGANIC CHEMISTRY
- Efficient Chemoenzymatic Synthesis of Optically Active Pregabalin from Racemic Isobutylsuccinonitrile
- (2019) Qin Zhang et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Consecutive Intermolecular Reductive Amination/Asymmetric Hydrogenation: Facile Access to Sterically Tunable Chiral Vicinal Diamines and N-Heterocyclic Carbenes
- (2019) Ya Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cobalt-Catalyzed Asymmetric Hydrogenation of C=N Bonds Enabled by Assisted Coordination and Nonbonding Interactions
- (2019) Yanhua Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Josiphos-Type Binaphane Ligands for Iridium-Catalyzed Enantioselective Hydrogenation of 1-Aryl-Substituted Dihydroisoquinolines
- (2019) Huifang Nie et al. ORGANIC LETTERS
- A Bulky Three-Hindered Quadrant Bisphosphine Ligand: Synthesis and Application in Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes
- (2019) Yuuki Sawatsugawa et al. ORGANIC LETTERS
- Rh-Catalyzed Asymmetric Hydrogenation of (Z)-β-Phosphorylated Enamides: Highly Enantioselective Access to β-Aminophosphines
- (2019) Hong-Quan Du et al. ORGANIC LETTERS
- Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of α-Iminoesters
- (2019) Jianzhong Chen et al. ORGANIC LETTERS
- Nickel-Catalyzed Chemoselective Asymmetric Hydrogenation of α,β-Unsaturated Ketoimines: An Efficient Approach to Chiral Allylic Amines
- (2019) Xiang Zhao et al. ORGANIC LETTERS
- Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides
- (2019) Albert Cabré et al. ORGANIC LETTERS
- Ir/Thioether–Carbene, −Phosphinite, and −Phosphite Complexes for Asymmetric Hydrogenation. A Case for Comparison
- (2019) Pol de la Cruz-Sánchez et al. ORGANOMETALLICS
- Josiphos-type binaphane ligands for the asymmetric Ir-catalyzed hydrogenation of acyclic aromatic N-aryl imines
- (2019) Dongxu Zhang et al. CATALYSIS COMMUNICATIONS
- Highly Diastereo- and Enantioselective Ir-Catalyzed Hydrogenation of 2,3-Disubstituted Quinolines with Structurally Fine-Tuned Phosphine–Phosphoramidite Ligands
- (2019) Xin-Hu Hu et al. ORGANIC LETTERS
- Palladium-Catalyzed Dual Ligand-Enabled Alkylation of Silyl Enol Ether and Enamide under Irradiation: Scope, Mechanism, and Theoretical Elucidation of Hybrid Alkyl Pd(I)-Radical Species
- (2019) Bin Zhao et al. ACS Catalysis
- Facile Synthesis of Chiral Cyclic Ureas through Hydrogenation of 2-Hydroxypyrimidine/Pyrimidin-2(1H )-one Tautomers
- (2018) Guang-Shou Feng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design, Synthesis, and Application of Chiral C 2 -Symmetric Spiroketal-Containing Ligands in Transition-Metal Catalysis
- (2018) Alonso J. Argüelles et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A one-pot process for the enantioselective synthesis of tetrahydroquinolines and tetrahydroisoquinolines via asymmetric reductive amination (ARA)
- (2018) Tao Yang et al. CHEMICAL COMMUNICATIONS
- Rhodium-catalyzed asymmetric hydrogenation of β-branched enamides for the synthesis of β-stereogenic amines
- (2018) Jian Zhang et al. CHEMICAL COMMUNICATIONS
- Dual Stereocontrol for Enantioselective Hydrogenation of Dihydroisoquinolines Induced by Tuning the Amount of N -Bromosuccinimide
- (2018) Yue Ji et al. CHINESE JOURNAL OF CHEMISTRY
- Asymmetric Transfer and Pressure Hydrogenation with Earth-Abundant Transition Metal Catalysts
- (2018) Zhenfeng Zhang et al. CHINESE JOURNAL OF CHEMISTRY
- Regio-, Diastereo- and Enantioselective Synthesis of Piperidines with Three Stereogenic Centers from Isoxazolinones by Palladium/Iridium Relay Catalysis
- (2018) Stefan Rieckhoff et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- P-Stereogenic and Non-P-Stereogenic Ir–MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles
- (2018) Ernest Salomó et al. JOURNAL OF ORGANIC CHEMISTRY
- An Enantioselective Total Synthesis of (+)-Duocarmycin SA
- (2018) Michael A. Schmidt et al. JOURNAL OF ORGANIC CHEMISTRY
- Hydrogenation catalyst generates cyclic peptide stereocentres in sequence
- (2018) Diane N. Le et al. Nature Chemistry
- Organic synthesis provides opportunities to transform drug discovery
- (2018) David C. Blakemore et al. Nature Chemistry
- Ruthenium-Catalyzed Hydrogenation of Carbocyclic Aromatic Amines: Access to Chiral Exocyclic Amines
- (2018) Zhong Yan et al. ORGANIC LETTERS
- BABIPhos Family of Biaryl Dihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation
- (2018) Guisheng Li et al. ORGANIC LETTERS
- Enantioselective Synthesis of α-(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights
- (2018) Bo Qu et al. ORGANIC LETTERS
- Brønsted-Acid-Promoted Rh-Catalyzed Asymmetric Hydrogenation of N-Unprotected Indoles: A Cocatalysis of Transition Metal and Anion Binding
- (2018) Jialin Wen et al. ORGANIC LETTERS
- Total Synthesis of (R)-Sarkomycin Methyl Ester via Regioselective Intermolecular Pauson–Khand Reaction and Iridium-Catalyzed Asymmetric Isomerization
- (2018) Albert Cabré et al. ORGANIC LETTERS
- Correction to Brønsted-Acid-Promoted Rh-Catalyzed Asymmetric Hydrogenation of N-Unprotected Indoles: A Cocatalysis of Transition Metal and Anion Binding
- (2018) Jialin Wen et al. ORGANIC LETTERS
- Cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction
- (2018) Max R. Friedfeld et al. SCIENCE
- Rhodium-catalyzed asymmetric hydrogenation of β-cyanocinnamic esters with the assistance of a single hydrogen bond in a precise position
- (2018) Xiuxiu Li et al. Chemical Science
- Enantioselective synthesis of 2-oxazolidinones by ruthenium(ii)–NHC-catalysed asymmetric hydrogenation of 2-oxazolones
- (2018) Wei Li et al. Chemical Science
- Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination
- (2018) Zhao Wu et al. Nature Communications
- Highly Enantioselective Synthesis of Chiral γ-Lactams by Rh-Catalyzed Asymmetric Hydrogenation
- (2018) Qiwei Lang et al. ACS Catalysis
- Iridium-catalyzed Asymmetric Hydrogenation of Polycyclic Pyrrolo/Indolo[1,2-a ]quinoxalines and Phenanthridines
- (2018) Shu-Bo Hu et al. ADVANCED SYNTHESIS & CATALYSIS
- Rhodium-Catalyzed Chemo- and Enantioselective Hydrogenation of Alkynyl-Aryl Hydrazones
- (2018) Dongyang Fan et al. ADVANCED SYNTHESIS & CATALYSIS
- A New Phosphine-Amine-Oxazoline Ligand for Ru-Catalyzed Asymmetric Hydrogenation of N -Phosphinylimines
- (2018) Xiaochen Ma et al. CHINESE JOURNAL OF CHEMISTRY
- Pd/Zn(OTf)₂ Co-catalyzed Asymmetric Hydrogenation of Imines under Normal Pressure of Hydrogen
- (2018) Yang Gao et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Asymmetric Synthesis of Chiral Spiroketal Bisphosphine Ligands and Their Application in Enantioselective Olefin Hydrogenation
- (2018) Jian Huang et al. JOURNAL OF ORGANIC CHEMISTRY
- Nickel-Catalyzed Highly Enantioselective Hydrogenation of β-Acetylamino Vinylsulfones: Access to Chiral β-Amido Sulfones
- (2018) Jiao Long et al. ORGANIC LETTERS
- Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines
- (2018) Albert Cabré et al. ORGANIC LETTERS
- Total syntheses of (+)-bernumidine and its unnatural enantiomer
- (2018) Bianca K. Corrêa et al. TETRAHEDRON LETTERS
- Facile synthesis of chiral indolines through asymmetric hydrogenation of in situ generated indoles
- (2018) Chang-Bin Yu et al. Organic Chemistry Frontiers
- Iridium-Catalyzed Asymmetric Hydrogenation of N -Alkyl α-Aryl Furan-Containing Imines: an Efficient Route to Unnatural N -Alkyl Arylalanines and Related Derivatives.
- (2018) Javier Mazuela et al. ADVANCED SYNTHESIS & CATALYSIS
- Rapid Construction of Structurally Diverse Quinolizidines, Indolizidines, and Their Analogues via Ruthenium-Catalyzed Asymmetric Cascade Hydrogenation/Reductive Amination
- (2018) Ya Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- “Backdoor Induction” of Chirality: Trans-1,2-cyclohexanediamine as Key Building Block for Asymmetric Hydrogenation Catalysts
- (2018) Saša Opačak et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
- (2018) Ernest Salomó et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iridium-Catalyzed Asymmetric Hydrogenation of 4,6-Disubstituted 2-Hydroxypyrimidines
- (2018) Guang-Shou Feng et al. ORGANIC LETTERS
- Iridium-Catalyzed Asymmetric Hydrogenation of Tetrasubstituted α-Fluoro-β-enamino Esters: Efficient Access to Chiral α-Fluoro-β-amino Esters with Two Adjacent Tertiary Stereocenters
- (2018) Zhengyu Han et al. ORGANIC LETTERS
- Catalytic Homogeneous Asymmetric Hydrogenation: Successes and Opportunities
- (2018) Chris S. G. Seo et al. ORGANOMETALLICS
- Exploring the Alcohol Stability of Bis(phosphine) Cobalt Dialkyl Precatalysts in Asymmetric Alkene Hydrogenation
- (2018) Hongyu Zhong et al. ORGANOMETALLICS
- Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis
- (2018) Eric R. Welin et al. SCIENCE
- Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines
- (2018) Jianzhong Chen et al. Nature Communications
- Oxidoreductase-Catalyzed Synthesis of Chiral Amines
- (2018) Mahesh D. Patil et al. ACS Catalysis
- Asymmetric Hydrogenation of Disubstituted, Trisubstituted, and Tetrasubstituted Minimally Functionalized Olefins and Cyclic β-Enamides with Easily Accessible Ir–P,Oxazoline Catalysts
- (2018) Maria Biosca et al. ACS Catalysis
- Bidentate Phosphine-Phosphoramidite Ligands of the BettiPhos Family for Rh-Catalyzed Asymmetric Hydrogenation
- (2017) Christian Schmitz et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Asymmetric Hydrogenation of Cyclic Imines of Benzoazepines and Benzodiazepines with Chiral, Cationic Ruthenium-Diamine Catalysts
- (2017) Zhusheng Yang et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Evolution and Prospects of the Asymmetric Hydrogenation of Unfunctionalized Olefins
- (2017) Cristiana Margarita et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent Advances in Asymmetric Hydrogenation of Tetrasubstituted Olefins
- (2017) Stefan Kraft et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines
- (2017) Ying Zhang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Enantioselective Synthesis of α-Acetal-β′-Amino Ketone Derivatives by Rhodium-Catalyzed Asymmetric Hydrogenation
- (2017) Quentin Llopis et al. ORGANIC LETTERS
- Synthesis of Chiral γ-Lactams via in Situ Elimination/Iridium-Catalyzed Asymmetric Hydrogenation of Racemic γ-Hydroxy γ-Lactams
- (2017) Qianjia Yuan et al. ORGANIC LETTERS
- Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib
- (2017) Chong Han et al. ORGANIC LETTERS
- Iridium-Catalyzed Asymmetric Hydrogenation of β,γ-Unsaturated γ-Lactams: Scope and Mechanistic Studies
- (2017) Qianjia Yuan et al. ORGANIC LETTERS
- Nickel-Catalyzed Enantioselective Hydrogenation of β-(Acylamino)acrylates: Synthesis of Chiral β-Amino Acid Derivatives
- (2017) Xiuxiu Li et al. ORGANIC LETTERS
- Enantioselective Direct Synthesis of Free Cyclic Amines via Intramolecular Reductive Amination
- (2017) Ying Zhang et al. ORGANIC LETTERS
- Rh/DuanPhos-Catalyzed Asymmetric Hydrogenation of β-Acetylamino Vinylsulfides: An Approach to Chiral β-Acetylamino Sulfides
- (2017) Wenchao Gao et al. ORGANIC LETTERS
- Ruthenium-Catalyzed Enantioselective Hydrogenation of Phenanthridine Derivatives
- (2017) Zhusheng Yang et al. ORGANIC LETTERS
- Asymmetric Hydrogenation of Isoquinolines and Pyridines Using Hydrogen Halide Generated in Situ as Activator
- (2017) Mu-Wang Chen et al. ORGANIC LETTERS
- Access to Chiral Seven-Member Cyclic Amines via Rh-Catalyzed Asymmetric Hydrogenation
- (2017) Pan Li et al. ORGANIC LETTERS
- Enantioselective Catalytic Methods for the Elaboration of Chiral Tetrahydro-β-carbolines and Related Scaffolds
- (2017) Xavier Guinchard et al. SYNTHESIS-STUTTGART
- Nickel-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins: an efficient approach to chiral amines
- (2017) Wenchao Gao et al. Chemical Science
- Revisiting the Stereodetermining Step in Enantioselective Iridium-Catalyzed Imine Hydrogenation
- (2017) Brandon Tutkowski et al. ACS Catalysis
- Chemoselective and Enantioselective Hydrogenation of 2,4-Diaryl-3H -benzo[b ]azepines Catalyzed by Dendritic Phosphinooxazoline Iridium Complexes
- (2017) Tingting Miao et al. Asian Journal of Organic Chemistry
- Ir/BiphPHOX-catalyzed asymmetric hydrogenation of 3-substituted 2,5-dihydropyrroles and 2,5-dihydrothiophene 1,1-dioxides
- (2017) Ke Meng et al. Organic Chemistry Frontiers
- Iridium-catalyzed asymmetric hydrogenation of cyclic iminium salts
- (2017) Yue Ji et al. Organic Chemistry Frontiers
- A Mixed Ligand Approach for the Asymmetric Hydrogenation of 2-Substituted Pyridinium Salts
- (2016) Marc Renom-Carrasco et al. ADVANCED SYNTHESIS & CATALYSIS
- One-Pot Two-Step Synthesis of Optically Activeα-Amino Phosphonates by Palladium-Catalyzed Hydrogenation/Hydrogenolysis ofα-Hydrazono Phosphonates
- (2016) Nataliya S. Goulioukina et al. ADVANCED SYNTHESIS & CATALYSIS
- Iridium-Catalyzed Asymmetric Hydrogenation of Tosylamido-Substituted Pyrazines for Constructing Chiral Tetrahydropyrazines with an Amidine Skelton
- (2016) Kosuke Higashida et al. ADVANCED SYNTHESIS & CATALYSIS
- Asymmetric Hydrogenation of 3-Amido-2-arylpyridinium Salts by Triply Chloride-Bridged Dinuclear Iridium Complexes Bearing Enantiopure Diphosphine Ligands: Synthesis of Neurokinin-1 Receptor Antagonist Derivatives
- (2016) Atsuhiro Iimuro et al. ADVANCED SYNTHESIS & CATALYSIS
- Asymmetric Hydrogenation of Azaindoles: Chemo- and Enantioselective Reduction of Fused Aromatic Ring Systems Consisting of Two Heteroarenes
- (2016) Yusuke Makida et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Enantioselective Direct Synthesis of Endocyclic Vicinal Diamines through Chiral Ru(diamine)-Catalyzed Hydrogenation of 2,2′-Bisquinoline Derivatives
- (2016) Wenpeng Ma et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides
- (2016) Ernest Salomó et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Enantioselective Synthesis of Indolines: Asymmetric Hydrogenation at Ambient Temperature and Pressure with Cationic Ruthenium Diamine Catalysts
- (2016) Zhusheng Yang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective synthesis of β-substituted chiral allylic amines via Rh-catalyzed asymmetric hydrogenation
- (2016) Qingli Wang et al. CHEMICAL COMMUNICATIONS
- Enantioselective hydrogenation of cyclic imines catalysed by Noyori–Ikariya half-sandwich complexes and their analogues
- (2016) B. Vilhanová et al. CHEMICAL COMMUNICATIONS
- Asymmetric Hydrogenation of Quinoline Derivatives Catalyzed by Cationic Transition Metal Complexes of Chiral Diamine Ligands: Scope, Mechanism and Catalyst Recycling
- (2016) Yi-Er Luo et al. CHEMICAL RECORD
- Asymmetric Hydrogenation of Nonaromatic Cyclic Substrates
- (2016) Zhenfeng Zhang et al. CHEMICAL REVIEWS
- Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts
- (2016) Marc Renom-Carrasco et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation of Isoxazolium Triflates with a Chiral Iridium Catalyst
- (2016) Ryuhei Ikeda et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation of Seven-Membered C=N-containing Heterocycles and Rationalization of the Enantioselectivity
- (2016) Bugga Balakrishna et al. CHEMISTRY-A EUROPEAN JOURNAL
- Phosphite-Thiother Ligands Derived from Carbohydrates allow the Enantioswitchable Hydrogenation of Cyclic β-Enamides by using either Rh or Ir Catalysts
- (2016) Jèssica Margalef et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Synthesis of Optically Active Spirocyclic Indoline Scaffolds through an Enantioselective Reduction of Indoles
- (2016) Ruediger Borrmann et al. CHEMISTRY-A EUROPEAN JOURNAL
- Rh-Catalyzed Chemo- and Enantioselective Hydrogenation of Allylic Hydrazones
- (2016) Qiupeng Hu et al. CHEMISTRY-A EUROPEAN JOURNAL
- Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s through Host-Guest Interactions
- (2016) Tianli Wang et al. Chemistry-An Asian Journal
- Enantioselective Hydrogenation of Diarylmethanimines for Synthesis of Chiral Diarylmethylamines
- (2016) Duanyang Kong et al. JOURNAL OF ORGANIC CHEMISTRY
- Sequential C–H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor
- (2016) Xudong Wei et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric Hydrogenation of Unprotected Indoles Catalyzed by η6-Arene/N-Me-sulfonyldiamine–Ru(II) Complexes
- (2016) Taichiro Touge et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,β-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation
- (2016) Michael Shevlin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination
- (2016) Shaolin Zhu et al. Nature Chemistry
- Rhodium-catalyzed asymmetric hydrogenation of unprotected β-enamine phosphonates
- (2016) Ming Zhou et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Enantioselective synthesis of β-amino acid derivatives via nickel-promoted regioselective carboxylation of ynamides and rhodium-catalyzed asymmetric hydrogenation
- (2016) Nozomi Saito et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides
- (2016) Wen-Xue Huang et al. ORGANIC LETTERS
- Rh-Catalyzed One-Pot Sequential Asymmetric Hydrogenation of α-Dehydroamino Ketones for the Synthesis of Chiral Cyclic trans-β-Amino Alcohols
- (2016) Qiupeng Hu et al. ORGANIC LETTERS
- Ruthenium-Catalyzed Enantioselective Hydrogenation of 1,8-Naphthyridine Derivatives
- (2016) Wenpeng Ma et al. ORGANIC LETTERS
- Asymmetric Reduction of Lactam-Based β-Aminoacrylates. Synthesis of Heterocyclic β2-Amino Acids
- (2016) Hugo Rego Campello et al. ORGANIC LETTERS
- Synthesis of Chiral Fluorinated Hydrazines via Pd-Catalyzed Asymmetric Hydrogenation
- (2016) Zhang-Pei Chen et al. ORGANIC LETTERS
- Enantioselective Synthesis of α-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation
- (2016) Zhong Yan et al. ORGANIC LETTERS
- Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts
- (2016) Bo Qu et al. ORGANIC LETTERS
- Development of the Asymmetric Hydrogenation Step for Multikilogram Production of Etamicastat
- (2016) Alexandre Beliaev ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Rhodium-Catalyzed Asymmetric Hydrogenation of N-(1-benzylpiperidin-3-yl)-enamides: An Efficient Access to Valuable Enantioenriched 3-Aminopiperidine Derivatives
- (2016) Bernard Boudet et al. SYNLETT
- Asymmetric Hydrogenation of Cyclic Imines and Enamines: Access to 1,5-Benzodiazepine Pharmacophores
- (2016) Magnus Rueping et al. SYNTHESIS-STUTTGART
- Recent Developments in Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones and Imines through Dynamic Kinetic Resolution
- (2016) Phannarath Phansavath et al. SYNTHESIS-STUTTGART
- Recent Developments in Asymmetric Allylic Amination Reactions
- (2016) P. Evans et al. SYNTHESIS-STUTTGART
- Asymmetric Hydrogenation of Heteroarenes with Multiple Heteroatoms
- (2016) Yong-Gui Zhou et al. SYNTHESIS-STUTTGART
- First catalytic asymmetric hydrogenation of quinoxaline-2-carboxylates
- (2016) Anna M. Maj et al. TETRAHEDRON
- New catalytic route for the synthesis of an optically active tetralone-derived amine for rotigotine
- (2016) Christopher J. Cobley et al. TETRAHEDRON LETTERS
- New synthetic strategy for chiral 2-oxazolidinones derivatives via rhodium-catalyzed asymmetric hydrogenation
- (2016) Qingli Wang et al. TETRAHEDRON LETTERS
- A supramolecularly tunable chiral diphosphine ligand: application to Rh and Ir-catalyzed enantioselective hydrogenation
- (2016) Xi-Chang Zhang et al. Chemical Science
- Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding
- (2016) Jialin Wen et al. Chemical Science
- Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatics Bearing a Hydroxyl Group, 3-Hydroxypyridinium Salts
- (2016) Wen-Xue Huang et al. ACS Catalysis
- PHOX-Based Phosphite-Oxazoline Ligands for the Enantioselective Ir-Catalyzed Hydrogenation of Cyclic β-Enamides
- (2016) Marc Magre et al. ACS Catalysis
- N-Heterocyclic Carbenes in Asymmetric Hydrogenation
- (2016) Dongbing Zhao et al. ACS Catalysis
- Enantioselective Hydrogenation of Ketones Catalyzed by Chiral Cobalt Complexes Containing PNNP Ligand
- (2016) Dong Zhang et al. Asian Journal of Organic Chemistry
- Iron-, Cobalt-, and Nickel-Catalyzed Asymmetric Transfer Hydrogenation and Asymmetric Hydrogenation of Ketones
- (2015) Yan-Yun Li et al. ACCOUNTS OF CHEMICAL RESEARCH
- Iron- and Cobalt-Catalyzed Alkene Hydrogenation: Catalysis with Both Redox-Active and Strong Field Ligands
- (2015) Paul J. Chirik ACCOUNTS OF CHEMICAL RESEARCH
- Disulfonimide-Catalyzed Asymmetric Reduction ofN-Alkyl Imines
- (2015) Vijay N. Wakchaure et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalytic Asymmetric Hydrogenation of Pyrimidines
- (2015) Ryoichi Kuwano et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Ruthenium-Catalyzed Hydrogenation of 2,6-Disubstituted 1,5-Naphthyridines: Access to Chiral 1,5-Diaza-cis-Decalins
- (2015) Jianwei Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes
- (2015) Michael T. Pirnot et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Phospholane-Phosphoramidite Ligands and their Application in Asymmetric Catalysis
- (2015) Tim Hammerer et al. ChemCatChem
- Stereospecific SN2@P reactions: novel access to bulky P-stereogenic ligands
- (2015) Sílvia Orgué et al. CHEMICAL COMMUNICATIONS
- Asymmetric hydrogenation of quinazolinium salts catalysed by halide-bridged dinuclear iridium complexes bearing chiral diphosphine ligands
- (2015) Yusuke Kita et al. CHEMICAL COMMUNICATIONS
- Catalytic Asymmetric Transfer Hydrogenation of Imines: Recent Advances
- (2015) Francisco Foubelo et al. CHEMICAL RECORD
- Rhodium-catalyzed Asymmetric Hydrogenation of α-Dehydroamino Ketones: A General Approach to Chiral α-amino Ketones
- (2015) Wenchao Gao et al. Chemistry-An Asian Journal
- P-Trifluoromethyl ligands derived from Josiphos in the Ir-catalysed hydrogenation of 3,4-dihydroisoquinoline hydrochlorides
- (2015) R. Schwenk et al. DALTON TRANSACTIONS
- Iridium-Catalyzed Asymmetric Hydrogenation of 2-Pyridyl Cyclic Imines: A Highly Enantioselective Approach to Nicotine Derivatives
- (2015) Cui Guo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic, Asymmetric, and Stereodivergent Synthesis of Non-Symmetric β,β-Diaryl-α-Amino Acids
- (2015) Carmela Molinaro et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Relay Iron/Chiral Brønsted Acid Catalysis: Enantioselective Hydrogenation of Benzoxazinones
- (2015) Liang-Qiu Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly Efficient Rh-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Nitriles
- (2015) Qiaozhi Yan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Total Synthesis of Cyclomarin A, a Marine Cycloheptapeptide with Anti-Tuberculosis and Anti-Malaria Activity
- (2015) Philipp Barbie et al. ORGANIC LETTERS
- Highly Enantioselective Hydrogenation of ο-Alkoxy Tetrasubstituted Enamides Catalyzed by a Rh/(R,S)-JosiPhos Catalyst
- (2015) Jingjing Meng et al. ORGANIC LETTERS
- Formal Palladium-Catalyzed Asymmetric Hydrogenolysis of Racemic N-Sulfonyloxaziridines
- (2015) Bo Song et al. ORGANIC LETTERS
- Rh-Catalyzed Asymmetric Hydrogenation of Cyclic α-Dehydroamino Ketones
- (2015) Zhenfeng Zhang et al. ORGANIC LETTERS
- Highly Efficient Synthesis of Chiral α-CF3 Amines via Rh-Catalyzed Asymmetric Hydrogenation
- (2015) Jun Jiang et al. ORGANIC LETTERS
- Synthesis of Chiral β-Amino Nitroalkanes via Rhodium-Catalyzed Asymmetric Hydrogenation
- (2015) Pan Li et al. ORGANIC LETTERS
- Catalytic asymmetric hydroamination of unactivated internal olefins to aliphatic amines
- (2015) Y. Yang et al. SCIENCE
- Asymmetric Homogeneous Hydrogenation of 2-Pyridones
- (2015) Frank Glorius et al. SYNLETT
- Utilization of optically active secondary phosphine–boranes: synthesis of P-chiral diphosphines and their enantioinduction ability in rhodium-catalyzed asymmetric hydrogenation
- (2015) Tsuneo Imamoto et al. TETRAHEDRON
- Rh catalyzed asymmetric olefin hydrogenation: enamides, enol esters and beyond
- (2015) Patryk Kleman et al. TETRAHEDRON LETTERS
- Synthesis of new N-substituted chiral phosphine–phosphoramidite ligands and their application in asymmetric hydrogenations and allylic alkylations
- (2015) Szabolcs Balogh et al. TETRAHEDRON-ASYMMETRY
- Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations
- (2015) Zeng-bo Pang et al. TETRAHEDRON-ASYMMETRY
- Enantioselective synthesis of the apremilast aminosulfone using catalytic asymmetric hydrogenation
- (2015) Alexander L. Ruchelman et al. TETRAHEDRON-ASYMMETRY
- Pd-catalyzed asymmetric hydrogenation of fluorinated aromatic pyrazol-5-ols via capture of active tautomers
- (2015) Zhang-Pei Chen et al. Chemical Science
- Synthesis of Chiral Trifluoromethyl-Substituted Hydrazines via Pd-Catalyzed Asymmetric Hydrogenation and Reductive Amination
- (2015) Zhang-Pei Chen et al. ACS Catalysis
- Chiral phosphine-phosphoramidite ligands for highly enantioselective hydrogenation of N-arylimines
- (2015) Qing Li et al. RSC Advances
- Enantioselective synthesis of trifluoromethyl substituted piperidines with multiple stereogenic centers via hydrogenation of pyridinium hydrochlorides
- (2015) Mu-Wang Chen et al. Organic Chemistry Frontiers
- MaxPHOS Ligand: PH/NH Tautomerism and Rhodium- Catalyzed Asymmetric Hydrogenations
- (2014) Edgar Cristóbal-Lecina et al. ADVANCED SYNTHESIS & CATALYSIS
- A Mild Dihydrobenzooxaphosphole Oxazoline/Iridium Catalytic System for Asymmetric Hydrogenation of Unfunctionalized Dialins
- (2014) Bo Qu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Regio- and Enantioselective Synthesis of γ,δ-Unsaturated Amido Esters by Catalytic Hydrogenation of Conjugated Enamides
- (2014) Min Gao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Rhodium-Catalyzed Asymmetric Hydrogenation of Unprotected NH Imines Assisted by a Thiourea
- (2014) Qingyang Zhao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst
- (2014) Mingxin Chang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- P-Aryl-Diphenylphospholanes and their Phospholanium Salts as Efficient Monodentate Ligands for Asymmetric Rhodium-Catalyzed Hydrogenation
- (2014) Cristian Dobrota et al. ChemCatChem
- Palladium-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines
- (2014) Xian-Feng Cai et al. CHEMICAL COMMUNICATIONS
- Highly efficient iridium-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins
- (2014) Qiaozhi Yan et al. CHEMICAL COMMUNICATIONS
- Synthesis of Chiral Exocyclic Amines by Asymmetric Hydrogenation of Aromatic Quinolin-3-amines
- (2014) Xian-Feng Cai et al. CHEMISTRY-A EUROPEAN JOURNAL
- Efficient Asymmetric Hydrogenation of α-Acetamidocinnamates through a Simple, Readily Available Monodentate ChiralH-Phosphinate
- (2014) Xiang-Bo Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantiopure Narrow Bite-Angle POP Ligands: Synthesis and Catalytic Performance in Asymmetric Hydroformylations and Hydrogenations
- (2014) Héctor Fernández-Pérez et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Enantioselective Hydrogenation ofN-Aryl Imines Derived from Acetophenones by Using Ru-Pybox Complexes under Hydrogenation or Transfer Hydrogenation Conditions in Isopropanol
- (2014) Estefanía Menéndez-Pedregal et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enhancing Effects of Salt Formation on Catalytic Activity and Enantioselectivity for Asymmetric Hydrogenation of Isoquinolinium Salts by Dinuclear Halide-Bridged Iridium Complexes Bearing Chiral Diphosphine Ligands
- (2014) Yusuke Kita et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective imine hydrogenation with iridium-catalysts: Reactions, mechanisms and stereocontrol
- (2014) Kathrin Helen Hopmann et al. COORDINATION CHEMISTRY REVIEWS
- Metallacrown Ether Catalysts Containing Phosphine-Phosphite Polyether Ligands for Rh-Catalyzed Asymmetric Hydrogenation - Enhancements in Activity and Enantioselectivity
- (2014) Feng-Tao Song et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement
- (2014) Chang-Bin Yu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iron(II) Complexes Containing Unsymmetrical P–N–P′ Pincer Ligands for the Catalytic Asymmetric Hydrogenation of Ketones and Imines
- (2014) Paraskevi O. Lagaditis et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rhodium-Catalyzed Enantioselective Hydrogenation of Tetrasubstituted α-Acetoxy β-Enamido Esters: A New Approach to Chiral α-Hydroxyl-β-amino Acid Derivatives
- (2014) Qingli Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies
- (2014) Ying Duan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iridium-Catalyzed Asymmetric Hydrogenation of Pyrrolo[1,2-a]pyrazinium Salts
- (2014) Wen-Xue Huang et al. ORGANIC LETTERS
- Highly Enantioselective Synthesis of Chiral Cyclic Allylic Amines via Rh-Catalyzed Asymmetric Hydrogenation
- (2014) Ming Zhou et al. ORGANIC LETTERS
- Practical Asymmetric Hydrogenation-Based Synthesis of a Class-Selective Histone Deacetylase Inhibitor
- (2014) Junli Chen et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Development of an Enantioselective Hydrogenation Route to (S)-1-(2-(Methylsulfonyl)pyridin-4-yl)propan-1-amine
- (2014) Jonathan T. Reeves et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Asymmetric Hydrogenation of Imines via Metal–Organo Cooperative Catalysis
- (2014) Jianliang Xiao et al. SYNTHESIS-STUTTGART
- An enantioselective synthesis of a MEM-protected aetheramide A derivative
- (2014) Arun K. Ghosh et al. TETRAHEDRON LETTERS
- Rh-catalyzed asymmetric hydrogenation using a furanoside monophosphite second-generation ligand library: scope and limitations
- (2014) Sabina Alegre et al. TETRAHEDRON-ASYMMETRY
- Rhodium-Catalyzed Asymmetric Hydrogenation of β-Acetylamino Acrylosulfones: A Practical Approach to Chiral β-Amido Sulfones
- (2014) Jun Jiang et al. ACS Catalysis
- Efficient asymmetric hydrogenation of quinolines in neat water catalyzed by chiral cationic Ru-diamine complexes
- (2014) Zhusheng Yang et al. Catalysis Science & Technology
- Asymmetric hydrogenation of 3-substituted 2H-1,4-benzoxazines with chiral cationic Ru-MsDPEN catalysts: a remarkable counteranion effect
- (2014) Jie Qin et al. Organic Chemistry Frontiers
- Asymmetric Hydrogenation of Quinoxalines, Benzoxazines, and a Benzothiazine Catalyzed by Chiral Ruthenabicyclic Complexes
- (2013) Noriyoshi Arai et al. ADVANCED SYNTHESIS & CATALYSIS
- Highly Enantioselective Synthesis of Chiral Tetrahydroquinolines and Tetrahydroisoquinolines by Ruthenium-Catalyzed Asymmetric Hydrogenation in Ionic Liquid
- (2013) Zi-Yuan Ding et al. ADVANCED SYNTHESIS & CATALYSIS
- Ruthenium-NHC-Catalyzed Asymmetric Hydrogenation of Indolizines: Access to Indolizidine Alkaloids
- (2013) Nuria Ortega et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis of Chiral β-Arylamines by Asymmetric Hydrogenation
- (2013) Guodu Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iridium-Catalyzed Enantioselective Hydrogenation of Unsaturated Heterocyclic Acids
- (2013) Song Song et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cooperative Catalysis through Noncovalent Interactions
- (2013) Weijun Tang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Ruthenium-Catalyzed Hydrogenation of 2- and 2,9-Substituted 1,10-Phenanthrolines
- (2013) Tianli Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Chiral Aliphatic Amines through Asymmetric Hydrogenation
- (2013) Tang-Lin Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective Iridium-Catalyzed Hydrogenation of 1- and 3-Substituted Isoquinolinium Salts
- (2013) Zhi-Shi Ye et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Hydrogenation of Isoquinolinium Salts Catalyzed by Chiral Iridium Complexes: Direct Synthesis for Optically Active 1,2,3,4-Tetrahydroisoquinolines
- (2013) Atsuhiro Iimuro et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- An efficient route to chiral N-heterocycles bearing a C–F stereogenic center via asymmetric hydrogenation of fluorinated isoquinolines
- (2013) Ran-Ning Guo et al. CHEMICAL COMMUNICATIONS
- Asymmetric Hydrogenation of Olefins Using Chiral Crabtree-type Catalysts: Scope and Limitations
- (2013) J. Johan Verendel et al. CHEMICAL REVIEWS
- Iridium-catalyzed Asymmetric Hydrogenation of Pyridinium Salts for Constructing Multiple Stereogenic Centers on Piperidines
- (2013) Yusuke Kita et al. CHEMISTRY LETTERS
- Cooperative Iron-Brønsted Acid Catalysis: Enantioselective Hydrogenation of Quinoxalines and 2 H-1,4-Benzoxazines
- (2013) Steffen Fleischer et al. CHEMISTRY-A EUROPEAN JOURNAL
- Cooperative Catalysis: Combining an Achiral Metal Catalyst with a Chiral Brønsted Acid Enables Highly Enantioselective Hydrogenation of Imines
- (2013) Weijun Tang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Efficient Synthesis of Heterocyclic and Alicyclic β2-Amino Acid Derivatives by Catalytic Asymmetric Hydrogenation
- (2013) Lanning Li et al. Chemistry-An Asian Journal
- Highly Enantioselective Hydrogenation of 2,4-Diaryl-1,5-Benzodiazepines Catalyzed by Dendritic Phosphinooxazoline Iridium Complexes
- (2013) Baode Ma et al. Chemistry-An Asian Journal
- Asymmetric hydrogenation of unprotected indoles using iridium complexes derived from P–OP ligands and (reusable) Brønsted acids
- (2013) José Luis Núñez-Rico et al. GREEN CHEMISTRY
- Rhodium Phosphine–Phosphite Catalysts in the Hydrogenation of Challenging N-(3,4-dihydronaphthalen-2-yl) Amide Derivatives
- (2013) Inmaculada Arribas et al. JOURNAL OF ORGANIC CHEMISTRY
- Rhodium-Catalyzed Enantioselective Hydrogenation of Oxime Acetates
- (2013) Kexuan Huang et al. ORGANIC LETTERS
- Asymmetric Synthesis of Vabicaserin via Oxidative Multicomponent Annulation and Asymmetric Hydrogenation of a 3,4-Substituted Quinolinium Salt
- (2013) Vladimir Dragan et al. ORGANIC LETTERS
- [Ir(P−OP)]-Catalyzed Asymmetric Hydrogenation of Diversely Substituted C═N-Containing Heterocycles
- (2013) José Luis Núñez-Rico et al. ORGANIC LETTERS
- Small Bite-Angle P–OP Ligands for Asymmetric Hydroformylation and Hydrogenation
- (2013) Héctor Fernández-Pérez et al. ORGANIC LETTERS
- Direct Catalytic Asymmetric Reductive Amination of Simple Aromatic Ketones
- (2013) Mingxin Chang et al. ORGANIC LETTERS
- Rhodium-Catalyzed Enantioselective Hydrogenation of β-Acylamino Nitroolefins: A New Approach to Chiral β-Amino Nitroalkanes
- (2013) Ming Zhou et al. ORGANIC LETTERS
- Practical Asymmetric Synthesis of a Chiral Piperazinone Derivative
- (2013) Mark McLaughlin et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- The P-Chiral Phosphane Ligand (MeO-BIBOP) for Efficient and Practical Large-Scale Rh-Catalyzed Asymmetric Hydrogenation of N-Acetyl Enamides with High TONs
- (2013) Wenjie Li et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- An Efficient Catalytic Asymmetric Synthesis of a β2-Amino Acid on Multikilogram Scale
- (2013) Travis Remarchuk et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Novel Bis(1,3,2-diazaphospholidine) Ligands for Asymmetric Catalysis
- (2013) Inmaculada Arribas et al. ORGANOMETALLICS
- New Enantiopure P,P-Bidentate Bis(diamidophosphite) Ligands. Application in Asymmetric Rhodium-Catalyzed Hydrogenation
- (2013) Maritza J. Bravo et al. ORGANOMETALLICS
- Iridium-catalyzed asymmetric hydrogenation of dibenzo[b,f][1,4]thiazepines
- (2013) Ran-Ning Guo et al. PURE AND APPLIED CHEMISTRY
- Cobalt Precursors for High-Throughput Discovery of Base Metal Asymmetric Alkene Hydrogenation Catalysts
- (2013) M. R. Friedfeld et al. SCIENCE
- Enantioselective Synthesis of Endocyclic β-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Alkoxycarbonyl-2-Substituted Quinolines
- (2013) Yong-Gui Zhou et al. SYNTHESIS-STUTTGART
- Highly enantioselective hydrogenation of N-unprotected indoles using (S)-C10–BridgePHOS as the chiral ligand
- (2013) Chao Li et al. TETRAHEDRON
- Synthesis of new chiral 2-functionalized-1,2,3,4-tetrahydroquinoline derivatives via asymmetric hydrogenation of substituted quinolines
- (2013) Anna M. Maj et al. TETRAHEDRON
- Palladium-catalyzed asymmetric hydrogenation of dibenzo[b,f][1,4]thiazepines activated by Brønsted acid
- (2013) Jinzhu Wang TETRAHEDRON LETTERS
- Palladium-catalyzed asymmetric hydrogenation of fluorinated quinazolinones
- (2013) Ying Duan et al. TETRAHEDRON LETTERS
- Synthesis of chiral cyclic β-amino ketones by Ru-catalyzed asymmetric hydrogenation
- (2013) Kexuan Huang et al. TETRAHEDRON LETTERS
- Fine tuning of the structure of phosphine–phosphoramidites: application for rhodium-catalyzed asymmetric hydrogenations
- (2013) Szabolcs Balogh et al. TETRAHEDRON-ASYMMETRY
- Synthesis of enantiopure β2-homoalanine derivatives via rhodium catalyzed asymmetric hydrogenation
- (2013) Susan Lühr et al. TETRAHEDRON-ASYMMETRY
- Discovery of an iridacycle catalyst with improved reactivity and enantioselectivity in the hydrogenation of dialkyl ketimines
- (2013) York Schramm et al. Chemical Science
- Mechanism of Asymmetric Hydrogenation of β-Dehydroamino Acids Catalyzed by Rhodium Complexes: Large-Scale Experimental and Computational Study
- (2013) Ilya D. Gridnev et al. ACS Catalysis
- Iridium-Catalyzed Asymmetric Hydrogenation of Substituted Pyridines
- (2013) Alban Cadu et al. Asian Journal of Organic Chemistry
- Evolutionary Catalyst Screening: Iridium-Catalyzed Imine Hydrogenation
- (2012) Alexander M. Kluwer et al. ADVANCED SYNTHESIS & CATALYSIS
- Iridium-Catalyzed Asymmetric Hydrogenation of 3-Substituted 2H-1,4-Benzoxazines
- (2012) Kai Gao et al. ADVANCED SYNTHESIS & CATALYSIS
- Palladium-Catalyzed Asymmetric Hydrogenation ofN-Hydroxy-α-imino Phosphonates Using Brønsted Acid as Activator: The First Catalytic Enantioselective Approach to ChiralN-Hydroxy-α-amino Phosphonates
- (2012) Nataliya S. Goulioukina et al. ADVANCED SYNTHESIS & CATALYSIS
- Asymmetric Hydrogenation of N-Arylimines Catalyzed by the Xyl-Skewphos/DPEN-Ruthenium(II) Complex
- (2012) Noriyoshi Arai et al. ADVANCED SYNTHESIS & CATALYSIS
- SIAPhos: Phosphorylated Sulfonimidamides and their Use in Iridium-Catalyzed Asymmetric Hydrogenations of Sterically Hindered Cyclic Enamides
- (2012) Frederic W. Patureau et al. ADVANCED SYNTHESIS & CATALYSIS
- Brønsted Acid Activation Strategy in Transition-Metal Catalyzed Asymmetric Hydrogenation of N-Unprotected Imines, Enamines, and N-Heteroaromatic Compounds
- (2012) Zhengkun Yu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Hydrogenation of 2,4-Disubstituted 1,5-Benzodiazepines Using Cationic Ruthenium Diamine Catalysts: An Unusual Achiral Counteranion Induced Reversal of Enantioselectivity
- (2012) Zi-Yuan Ding et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective Iridium-Catalyzed Hydrogenation of 3,4-Disubstituted Isoquinolines
- (2012) Lei Shi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iridium-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts
- (2012) Zhi-Shi Ye et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric homogeneous hydrogenations at scale
- (2012) David J. Ager et al. CHEMICAL SOCIETY REVIEWS
- Recent advances in transition metal-catalyzed enantioselective hydrogenation of unprotected enamines
- (2012) Jian-Hua Xie et al. CHEMICAL SOCIETY REVIEWS
- Rhodium-catalysed asymmetric hydrogenation as a valuable synthetic tool for the preparation of chiral drugs
- (2012) Pablo Etayo et al. CHEMICAL SOCIETY REVIEWS
- Homogeneous palladium-catalyzed asymmetric hydrogenation
- (2012) Qing-An Chen et al. CHEMICAL SOCIETY REVIEWS
- Additive Effects of Amines on Asymmetric Hydrogenation of Quinoxalines Catalyzed by Chiral Iridium Complexes
- (2012) Takuto Nagano et al. CHEMISTRY-A EUROPEAN JOURNAL
- A Library Approach to the Development of BenzaPhos: Highly Efficient Chiral Supramolecular Ligands for Asymmetric Hydrogenation
- (2012) Luca Pignataro et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation Using Rhodium Complexes Generated from Mixtures of Monodentate Neutral and Anionic Phosphorus Ligands
- (2012) Dominik J. Frank et al. CHEMISTRY-A EUROPEAN JOURNAL
- Chiral Hetero- and Carbocyclic Compounds from the Asymmetric Hydrogenation of Cyclic Alkenes
- (2012) J. Johan Verendel et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Rh-catalyzed hydrogenation using a furanoside phosphite–phosphoroamidite and diphosphoroamidite ligand library
- (2012) Mercedes Coll et al. DALTON TRANSACTIONS
- The first example of asymmetric hydrogenation of imines with Co2(CO)8/(R)-BINAP as catalytic precursor
- (2012) Manuel Amézquita-Valencia et al. JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
- Three-Hindered Quadrant Phosphine Ligands with an Aromatic Ring Backbone for the Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes
- (2012) Zhenfeng Zhang et al. JOURNAL OF ORGANIC CHEMISTRY
- General Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxaline Derivatives Catalyzed by Iridium-Difluorphos: Unusual Halide Effect and Synthetic Application
- (2012) Damien Cartigny et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantiopure C1-Symmetric Bis(imino)pyridine Cobalt Complexes for Asymmetric Alkene Hydrogenation
- (2012) Sebastien Monfette et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dihydrophenanthridine: A New and Easily Regenerable NAD(P)H Model for Biomimetic Asymmetric Hydrogenation
- (2012) Qing-An Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines
- (2012) Kai Gao et al. ORGANIC LETTERS
- Chiral Phosphine–Phosphoramidite Ligands for Highly Efficient Ir-Catalyzed Asymmetric Hydrogenation of Sterically Hindered N-Arylimines
- (2012) Chuan-Jin Hou et al. ORGANIC LETTERS
- Enantioselective Synthesis of 1-Aryl-tetrahydroisoquinolines through Iridium Catalyzed Asymmetric Hydrogenation
- (2012) Farouk Berhal et al. ORGANIC LETTERS
- The Large-Scale Synthesis of (S)-N-Boc-bis(4-fluorophenyl)alanine
- (2012) Robert B. Appell et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- The Development of an Asymmetric Hydrogenation Process for the Preparation of Solifenacin
- (2012) Miloš Ružič et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Selection of an Enantioselective Process for the Preparation of a CGRP Receptor Inhibitor
- (2012) Reginald O. Cann et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Asymmetric hydrogenation of N-alkyl and N-aryl ketimines using chiral cationic Ru(diamine) complexes as catalysts: the counteranion and solvent effects, and substrate scope
- (2012) Fei Chen et al. TETRAHEDRON
- Enantioselective hydrogenation of (Z)- and (E)-β-arylenamides catalyzed by rhodium complexes of monodentate chiral spiro phosphorous ligands: a new access to chiral β-arylisopropylamines
- (2012) Shou-Fei Zhu et al. TETRAHEDRON
- Highly enantioselective hydrogenation of new 2-functionalized quinoline derivatives
- (2012) Anna M. Maj et al. TETRAHEDRON LETTERS
- Enantioselective straightforward access to benzo[b]thiophene analogs of Azatoxin
- (2012) Stéphanie Gracia et al. TETRAHEDRON LETTERS
- A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation
- (2012) De-Yang Zhang et al. TETRAHEDRON LETTERS
- Enantioselective Pd-catalyzed hydrogenation of tetrasubstituted olefins of cyclic β-(arylsulfonamido)acrylates
- (2012) Chang-Bin Yu et al. TETRAHEDRON LETTERS
- Novel phosphine–phosphites and their use in asymmetric hydrogenation
- (2012) Gergely Farkas et al. TETRAHEDRON-ASYMMETRY
- Synthesis of chiral β2-amino acids by asymmetric hydrogenation
- (2012) Susan Lühr et al. TETRAHEDRON-ASYMMETRY
- Asymmetric Hydrogenation of Cyclic Imines Catalyzed by Chiral Spiro Iridium Phosphoramidite Complexes for Enantioselective Synthesis of Tetrahydroisoquinolines
- (2012) Jian-Hua Xie et al. ACS Catalysis
- Highly Enantioselective Hydrogenation of β-Ketoenamides with the Rh-ZhangPhos Catalyst
- (2012) Kexuan Huang et al. ACS Catalysis
- Development of the BIPI ligands for asymmetric hydrogenation
- (2012) Carl A. Busacca et al. Catalysis Science & Technology
- New Synthetic Strategy for High-Enantiopurity N-Protected α-Amino Ketones and their Derivatives by Asymmetric Hydrogenation
- (2011) Tian Sun et al. ADVANCED SYNTHESIS & CATALYSIS
- Kilogram-Scale Asymmetric Ruthenium-Catalyzed Hydrogenation of a Tetrasubstituted Fluoroenamide
- (2011) Andreas Stumpf et al. ADVANCED SYNTHESIS & CATALYSIS
- Asymmetric Hydrogenation of α- and β-Enamido Phosphonates: Rhodium(I)/Monodentate Phosphoramidite Catalyst
- (2011) Jinzhu Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Highly Efficient and Enantioselective Access to Tetrahydroisoquinoline Alkaloids: Asymmetric Hydrogenation with an Iridium Catalyst
- (2011) Mingxin Chang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Graphical Abstract: Angew. Chem. Int. Ed. 38/2011
- (2011) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective Pd-catalyzed hydrogenation of enesulfonamides
- (2011) Chang-Bin Yu et al. CHEMICAL COMMUNICATIONS
- Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: substituted dibenzo[b,f][1,4]oxazepines
- (2011) Kai Gao et al. CHEMICAL COMMUNICATIONS
- Asymmetric hydrogenation of alkenes lacking coordinating groups
- (2011) David H. Woodmansee et al. CHEMICAL COMMUNICATIONS
- Asymmetric Strecker Reactions
- (2011) Jun Wang et al. CHEMICAL REVIEWS
- Advances in the Chemistry of Tetrahydroquinolines
- (2011) Vellaisamy Sridharan et al. CHEMICAL REVIEWS
- Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update
- (2011) Shu̅ Kobayashi et al. CHEMICAL REVIEWS
- Asymmetric Hydrogenation of Heteroarenes and Arenes
- (2011) Duo-Sheng Wang et al. CHEMICAL REVIEWS
- Enantioselective Access to Chiral Drugs by using Asymmetric Hydrogenation Catalyzed by Rh(POP) Complexes
- (2011) Pablo Etayo et al. CHEMISTRY-A EUROPEAN JOURNAL
- An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Brønsted Acid/Pd-Complex-Promoted Tandem Reactions
- (2011) Ying Duan et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation of N-Alkyl Ketimines with Phosphine-Free, Chiral, Cationic Ru-MsDPEN Catalysts
- (2011) Fei Chen et al. CHEMISTRY-A EUROPEAN JOURNAL
- Advances in catalytic metal-free reductions: from bio-inspired concepts to applications in the organocatalytic synthesis of pharmaceuticals and natural products
- (2011) Magnus Rueping et al. GREEN CHEMISTRY
- The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
- (2011) Stephen D. Roughley et al. JOURNAL OF MEDICINAL CHEMISTRY
- Asymmetric Syntheses of α-Methyl γ-Amino Acid Derivatives
- (2011) Ye Zhu et al. JOURNAL OF ORGANIC CHEMISTRY
- Catalytic Asymmetric Hydrogenation of 2,3,5-Trisubstituted Pyrroles
- (2011) Ryoichi Kuwano et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enantioselective Supramolecular Catalysis Induced by Remote Chiral Diols
- (2011) Piet W. N. M. van Leeuwen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly Enantioselective Hydrogenation of Quinolines Using Phosphine-Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism, and Origin of Enantioselectivity
- (2011) Tianli Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic Asymmetric Hydrogenation of N-Boc-Imidazoles and Oxazoles
- (2011) Ryoichi Kuwano et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly Enantioselective Partial Hydrogenation of Simple Pyrroles: A Facile Access to Chiral 1-Pyrrolines
- (2011) Duo-Sheng Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rigid P-Chiral Phosphine Ligands with tert-Butylmethylphosphino Groups for Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes
- (2011) Tsuneo Imamoto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Protecting-group-free synthesis of a dual CCK1/CCK2 receptor antagonist
- (2011) Jing Liu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles
- (2011) Ying Duan et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric Hydrogenation of 2- and 2,3-Substituted Quinoxalines with Chiral Cationic Ruthenium Diamine Catalysts
- (2011) Jie Qin et al. ORGANIC LETTERS
- Efficient Enantioselective Synthesis of 3-Aminochroman Derivatives Through Ruthenium-Synphos Catalyzed Asymmetric Hydrogenation
- (2011) Zi Wu et al. ORGANIC LETTERS
- Highly Effective Asymmetric Hydrogenation of CyclicN-Alkyl Imines with Chiral Cationic Ru-MsDPEN Catalysts‡
- (2011) Fei Chen et al. ORGANIC LETTERS
- Practical, Catalytic Enantioselective Hydrogenation to SynthesizeN-Unprotected β-Amino Esters
- (2011) Kazuhiko Matsumura et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Development of a Commercial Process for (S)-β-Phenylalanine(1)
- (2011) J. Ian Grayson et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Large-Scale Synthesis of a Substitutedd-Phenylalanine Using Asymmetric Hydrogenation
- (2011) Martin E. Fox et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- The Development of a Practical Multikilogram Synthesis of the Chiral β-Amino Acid Imagabalin Hydrochloride (PD-0332334) via Asymmetric Hydrogenation
- (2011) Melissa Birch et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Asymmetric Synthesis of (S)-3-Amino-4-methoxy-butan-1-ol by Way of Reductive Amination
- (2011) Patrizio Mattei et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- On the Mechanism of Iridium-Catalyzed Asymmetric Hydrogenation of Imines and Alkenes: A Theoretical Study
- (2011) Kathrin Helen Hopmann et al. ORGANOMETALLICS
- Chiral Rhodium Complexes Derived From Electron-Rich Phosphine-Phosphites as Asymmetric Hydrogenation Catalysts
- (2011) Pablo Etayo et al. ORGANOMETALLICS
- The use of a new carboranylamidophosphite ligand in the asymmetric Rh-catalyzed hydrogenation of α- and β-dehydroamino acid derivatives
- (2011) Sergey E. Lyubimov et al. POLYHEDRON
- Synthesis of Electronically Deficient Atropisomeric Bisphosphine Ligands and Their Application in Asymmetric Hydrogenation of Quinolines
- (2011) Min-Can Wang et al. SYNTHESIS-STUTTGART
- Catalytic asymmetric hydrogenation of heterocyclic ketone-derived hydrazones, pronounced solvent effect on the inversion of configuration
- (2011) Nizar Haddad et al. TETRAHEDRON LETTERS
- Rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles
- (2011) Miaofeng Ma et al. TETRAHEDRON-ASYMMETRY
- Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles
- (2011) Duo-Sheng Wang et al. Chemical Science
- Iridium-Catalyzed Asymmetric Hydrogenation of Quinoline Derivatives with C3*-TunePhos
- (2010) Fa-Rong Gou et al. ADVANCED SYNTHESIS & CATALYSIS
- Iridium-Catalyzed Enantioselective Hydrogenation of Cyclic Imines
- (2010) Mingxin Chang et al. ADVANCED SYNTHESIS & CATALYSIS
- Palladium-Catalyzed Asymmetric Hydrogenation of Simple Ketimines Using a Brønsted Acid as Activator
- (2010) Xiao-Yu Zhou et al. ADVANCED SYNTHESIS & CATALYSIS
- Novel Amido-Complexes for the Efficient Asymmetric Hydrogenation of Imines
- (2010) Kathrin Kutlescha et al. ADVANCED SYNTHESIS & CATALYSIS
- Enantioselective Hydrogenation of α-Dehydroamino Acid Esters Catalyzed by Rhodium Complexes with Chiral Bisaminophosphine Ligands
- (2010) Xianfeng Sun et al. ADVANCED SYNTHESIS & CATALYSIS
- A General Approach to the Synthesis of β2-Amino Acid Derivatives via Highly Efficient Catalytic Asymmetric Hydrogenation of α-Aminomethylacrylates
- (2010) Yujuan Guo et al. ADVANCED SYNTHESIS & CATALYSIS
- Highly Enantioselective Hydrogenation of Quinoline and Pyridine Derivatives with Iridium-(P-Phos) Catalyst
- (2010) Wei-Jun Tang et al. ADVANCED SYNTHESIS & CATALYSIS
- Iridium-Difluorphos-Catalyzed Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxalines: A General and Efficient Route into Tetrahydroquinoxalines
- (2010) Damien Cartigny et al. ADVANCED SYNTHESIS & CATALYSIS
- Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction
- (2010) Thomas C. Nugent et al. ADVANCED SYNTHESIS & CATALYSIS
- Electron-Donating and Rigid P-Stereogenic Bisphospholane Ligands for Highly Enantioselective Rhodium-Catalyzed Asymmetric Hydrogenations
- (2010) Xiaowei Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Primary and Secondary Aminophosphines as Novel P-Stereogenic Building Blocks for Ligand Synthesis
- (2010) Marc Revés et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highlights of Transition Metal-Catalyzed Asymmetric Hydrogenation of Imines
- (2010) Nicolas Fleury-Brégeot et al. ChemCatChem
- Design and synthesis of a novel three-hindered quadrant bisphosphine ligand and its application in asymmetric hydrogenation
- (2010) Kexuan Huang et al. CHEMICAL COMMUNICATIONS
- Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines
- (2010) Jian-Hua Xie et al. CHEMICAL REVIEWS
- Recent advances in the catalytic asymmetric synthesis of β-amino acids
- (2010) Barbara Weiner et al. CHEMICAL SOCIETY REVIEWS
- Iridium-Catalyzed Asymmetric Hydrogenation of Imines
- (2010) Alejandro Baeza et al. CHEMISTRY-A EUROPEAN JOURNAL
- Quinaphos and Dihydro-Quinaphos Phosphine-Phosphoramidite Ligands for Asymmetric Hydrogenation
- (2010) Thomas Pullmann et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Modular POP Ligands for Asymmetric Hydrogenation: Synthesis, Catalytic Activity, and Mechanism
- (2010) Héctor Fernández-Pérez et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Efficient RhI-Catalyzed Asymmetric Hydrogenation of β-Amino Acrylonitriles
- (2010) Miaofeng Ma et al. CHEMISTRY-A EUROPEAN JOURNAL
- Iridium-Catalyzed Asymmetric Hydrogenation of N-Protected Indoles
- (2010) Alejandro Baeza et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Hydrogenation of Cyclic N-Sulfonylimines with Phosphine-Free Chiral Cationic Ru-MsDPEN Catalysts
- (2010) Fei Chen et al. CHINESE JOURNAL OF CHEMISTRY
- Asymmetric Hydrogenation of Unfunctionalized Enamines Catalyzed by Iridium Complexes of Chiral Spiro N,N-Diarylphosphoramidites
- (2010) Pucha Yan et al. CHINESE JOURNAL OF CHEMISTRY
- Large-Scale Asymmetric Synthesis of a Cathepsin S Inhibitor
- (2010) Jon C. Lorenz et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Synthesis of Optically Pure β-Amino Ketones and γ-Aryl Amines by Rh-Catalyzed Asymmetric Hydrogenation
- (2010) Huiling Geng et al. JOURNAL OF ORGANIC CHEMISTRY
- Highly Flexible Synthesis of Chiral Azacycles via Iridium-Catalyzed Hydrogenation
- (2010) J. Johan Verendel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly Efficient Iridium-Catalyzed Asymmetric Hydrogenation of Unprotected β-Enamine Esters
- (2010) Guohua Hou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iridium−Monodentate Phosphoramidite-Catalyzed Asymmetric Hydrogenation of Substituted Benzophenone N−H Imines
- (2010) Guohua Hou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Brønsted Acids
- (2010) Duo-Sheng Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Phosphine-free chiral metal catalysts for highly effective asymmetric catalytic hydrogenation
- (2010) Yan-Mei He et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of β-(acylamino)acrylates: significant effect of substituents on 3,3′-positions of binaphthyl moiety
- (2010) Xiao-Mao Zhou et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Highly efficient and enantioselective hydrogenation of quinolines and pyridines with Ir-Difluorphos catalyst
- (2010) Weijun Tang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Enantiopure 1,2-Bis(tert-butylmethylphosphino)benzene as a Highly Efficient Ligand in Rhodium-Catalyzed Asymmetric Hydrogenation
- (2010) Ken Tamura et al. ORGANIC LETTERS
- Heavyweight “R-SMS-Phos” Ligands in the Olefins’ Hydrogenation Arena
- (2010) Borut Zupančič et al. ORGANIC LETTERS
- Impact on Hydrogenation Catalytic Cycle of the R Groups’ Cyclic Feature in “R-SMS-Phos”
- (2010) Borut Zupančič et al. ORGANIC LETTERS
- Asymmetric Hydrogenation of Protected Allylic Amines
- (2010) Dietrich P. Steinhuebel et al. ORGANIC LETTERS
- Enantioselective Synthesis of β-Trifluoromethyl α-Amino Acids
- (2010) Cyril Benhaim et al. ORGANIC LETTERS
- Novel and Efficient Chiral Bisphosphorus Ligands for Rhodium-Catalyzed Asymmetric Hydrogenation
- (2010) Wenjun Tang et al. ORGANIC LETTERS
- Rapid Identification of a Scalable Catalyst for the Asymmetric Hydrogenation of a Sterically Demanding Aryl Enamide
- (2010) Laurent Lefort et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Asymmetric hydrogenation of quinolines activated by Brønsted acids
- (2010) Duo-Sheng Wang et al. TETRAHEDRON LETTERS
- Sequential perfluoroalkylation and asymmetric reduction of nitriles triggered with perfluoroalkyl titanates: catalytic asymmetric synthesis of perfluoroalkyl amines
- (2010) Koichi Mikami et al. TETRAHEDRON LETTERS
- Enantioselective hydrogenation of indoles derivatives catalyzed by Walphos/rhodium complexes
- (2010) Anna M. Maj et al. TETRAHEDRON-ASYMMETRY
- Asymmetric hydrogenation of trisubstituted N-acetyl enamides derived from 2-tetralones using ruthenium-SYNPHOS catalysts: a practical synthetic approach to the preparation of β3-adrenergic agonist SR58611A
- (2010) Cyrielle Pautigny et al. TETRAHEDRON-ASYMMETRY
- Highly enantioselective synthesis of α-(perfluoroalkyl)amines via hydrogenation of enamide precursors in the presence of chiraphos-rhodium catalyst
- (2010) Koichi Mikami et al. TETRAHEDRON-ASYMMETRY
- Asymmetric hydrogenation of 2-substituted N-protected-indoles catalyzed by rhodium complexes of BINOL-derived phosphoramidites
- (2010) Nataša Mršić et al. TETRAHEDRON-ASYMMETRY
- Highly Efficient and Enantioselective Iridium-Catalyzed Asymmetric Hydrogenation of N-Arylimines
- (2009) Wei Li et al. ADVANCED SYNTHESIS & CATALYSIS
- Iridium-Catalysed Asymmetric Hydrogenation of Enamides in the Presence of 3,3′-Substituted H8-Phosphoramidites
- (2009) Giulia Erre et al. ADVANCED SYNTHESIS & CATALYSIS
- Enantioselective Synthesis of Chiral Tetrahydroisoquinolines by Iridium-Catalyzed Asymmetric Hydrogenation of Enamines
- (2009) Pu-Cha Yan et al. ADVANCED SYNTHESIS & CATALYSIS
- Highly Enantioselective Iridium-Catalyzed Hydrogenation of Trisubstituted Olefins, α,β-Unsaturated Ketones and Imines with Chiral Benzylic Substituted P,N Ligands
- (2009) Wei-Jing Lu et al. ADVANCED SYNTHESIS & CATALYSIS
- A Palladium(II)-Catalyzed Synthesis of Spiroacetals through a One-Pot Multicomponent Cascade Reaction
- (2009) José Barluenga et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Spiro[4,4]-1,6-nonadiene-Based Phosphine-Oxazoline Ligands for Iridium-Catalyzed Enantioselective Hydrogenation of Ketimines
- (2009) Zhaobin Han et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Hydrogenation of Quinoxalines with Diphosphinite Ligands: A Practical Synthesis of Enantioenriched, Substituted Tetrahydroquinoxalines
- (2009) Weijun Tang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Homogeneous Chiral Nickel-Catalyzed Asymmetric Hydrogenation of Substituted Aromaticα-Aminoketone Hydrochlorides through Dynamic Kinetic Resolution
- (2009) Takuya Hibino et al. ChemCatChem
- Synthesis of Melatonin Receptor Agonist Ramelteon via Rh-catalyzed Asymmetric Hydrogenation of an Allylamine
- (2009) Masayuki Yamashita et al. CHEMISTRY LETTERS
- Iridium-Catalyzed Asymmetric Hydrogenation of Unfunctionalized Enamines
- (2009) Alejandro Baeza et al. CHEMISTRY-A EUROPEAN JOURNAL
- Unprecedented Halide Dependence on Catalytic Asymmetric Hydrogenation of 2-Aryl- and 2-Alkyl-Substituted Quinolinium Salts by Using Ir Complexes with Difluorphos and Halide Ligands
- (2009) Hiroshi Tadaoka et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly enantioselective hydrogenation of quinolines under solvent-free or highly concentrated conditions
- (2009) Zhi-Jian Wang et al. GREEN CHEMISTRY
- Highly Enantioselective Synthesis of Sultams via Pd-Catalyzed Hydrogenation
- (2009) Chang-Bin Yu et al. JOURNAL OF ORGANIC CHEMISTRY
- Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Benzylquinolines and 2-Functionalized and 2,3-Disubstituted Quinolines
- (2009) Da-Wei Wang et al. JOURNAL OF ORGANIC CHEMISTRY
- Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines
- (2009) Guo-Hua Hou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iridium/Monodentate Phosphoramidite Catalyzed Asymmetric Hydrogenation ofN-Aryl Imines
- (2009) Nataša Mršić et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enantioselective Hydrogenation of N−H Imines
- (2009) Guohua Hou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly Efficient Asymmetric Synthesis of Sitagliptin
- (2009) Karl B. Hansen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Direct Asymmetric Reductive Amination
- (2009) Dietrich Steinhuebel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic Asymmetric Synthesis of an HIV Integrase Inhibitor
- (2009) Yong-Li Zhong et al. ORGANIC LETTERS
- Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation
- (2009) Wenjun Tang et al. ORGANIC LETTERS
- Catalytic Enantioselective Hydrogenation ofN-Alkoxycarbonyl Hydrazones: A Practical Synthesis of Chiral Hydrazines
- (2009) Naoki Yoshikawa et al. ORGANIC LETTERS
- New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity
- (2009) Debra J. Wallace et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Highly enantioselective Ir-catalyzed hydrogenation of exocyclic enamines
- (2009) Xiao-Bing Wang et al. TETRAHEDRON-ASYMMETRY
- Chiral Diphosphine and Monodentate Phosphorus Ligands on a Spiro Scaffold for Transition-Metal-Catalyzed Asymmetric Reactions
- (2008) Jian-Hua Xie et al. ACCOUNTS OF CHEMICAL RESEARCH
- Modular Phosphine-Aminophosphine Ligands Based on Chiral 1,2,3,4-Tetrahydro-1-naphthylamine Backbone: A New Class of Practical Ligands for Enantioselective Hydrogenations
- (2008) Min Qiu et al. ADVANCED SYNTHESIS & CATALYSIS
- Hydrogenation of Quinolines Using a Recyclable Phosphine-Free Chiral Cationic Ruthenium Catalyst: Enhancement of Catalyst Stability and Selectivity in an Ionic Liquid
- (2008) Haifeng Zhou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Efficient Synthesis of Chiral β-Arylisopropylamines by Using Catalytic Asymmetric Hydrogenation
- (2008) Jian Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Readily Available Chiral Phosphine−Aminophosphine Ligands for Highly Efficient Rh-Catalyzed Asymmetric Hydrogenation of α-Enol Ester Phosphonates and α-Enamido Phosphonates
- (2008) Dao-Yong Wang et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Synthesis of β2-Amino Acids via Rh-Catalyzed Asymmetric Hydrogenation with BoPhoz-Type Ligands: Important Influence of an N−H Proton in the Ligand on the Enantioselectivity
- (2008) Jun Deng et al. JOURNAL OF ORGANIC CHEMISTRY
- Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines
- (2008) Chaoqun Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric Hydrogenation of Cyclic Imines with an Ionic Cp*Rh(III) Catalyst
- (2008) Chaoqun Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric Hydrogenation Catalyzed by a Rhodium Complex of (R)-(tert-Butylmethylphosphino)(di-tert-butylphosphino)methane: Scope of Enantioselectivity and Mechanistic Study
- (2008) Ilya D. Gridnev et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Air-Stable and Phosphine-Free Iridium Catalysts for Highly Enantioselective Hydrogenation of Quinoline Derivatives†
- (2008) Zhi-Wei Li et al. ORGANIC LETTERS
- Regio- and Stereoselective Hydroamidation of 1-Alkynylphosphine Sulfides Catalyzed by Cesium Base
- (2008) Azusa Kondoh et al. ORGANIC LETTERS
- A Convenient Synthesis and the Asymmetric Hydrogenation ofN-Phthaloyl Dehydroamino Acid Esters
- (2008) Jian Chen et al. ORGANIC LETTERS
- Enantioselective Synthesis of Cyclic Sulfamidates via Pd-Catalyzed Hydrogenation
- (2008) You-Qing Wang et al. ORGANIC LETTERS
- Iridium-catalyzed asymmetric hydrogenation of pyridine derivatives, 7,8-dihydro-quinolin-5(6H)-ones
- (2008) Xiao-Bing Wang et al. TETRAHEDRON LETTERS
- Fluorine in medicinal chemistry
- (2007) Sophie Purser et al. CHEMICAL SOCIETY REVIEWS
- Catalytic Asymmetric Hydrogenation of 2,3,5-Trisubstituted Pyrroles
- (2007) Ryoichi Kuwano et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started