期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 353, 期 18, 页码 3367-3372出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201100195
关键词
amines; enantioselectivity; fluorine; high-throughput screen (HTS); homogeneous catalysis; hydrogenation; ruthenium; tetrasubstituted ss-fluoroenamides
Ruthenium-catalyzed asymmetric homogeneous hydrogenation (AHH) is used as the key step of a multi-kilogram scale synthesis of an enantiomeric fluoropiperidine. The AHH of a tetrasubstituted beta-fluoroenamide is carried out under mild conditions using a Ru/Josiphos catalyst with high ee (98%).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
