Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis

Strategy for Extending Half-life in Drug Design and Its Significance

(2018) Hakan Gunaydin et al.   ACS Medicinal Chemistry Letters

A Concise and Practical Semisynthesis of Ecteinascidin 743 and (-)-Jorumycin

(2017) Shanghu Xu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Isoquinoline Alkaloids: 2004–2015

(2016) Maria Chrzanowska et al.   CHEMICAL REVIEWS

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of Thailanstatin A

(2016) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding

(2016) Jialin Wen et al.   Chemical Science

Targeting PI3K/mTOR Overcomes Resistance to HER2-Targeted Therapy Independent of Feedback Activation of AKT

(2014) N. A. O'Brien et al.   CLINICAL CANCER RESEARCH

Asymmetric Hydrogenation of Isoquinolinium Salts Catalyzed by Chiral Iridium Complexes: Direct Synthesis for Optically Active 1,2,3,4-Tetrahydroisoquinolines

(2013) Atsuhiro Iimuro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Total Synthesis of (−)-Jorunnamycins A and C and (−)-Jorumycin from l-Tyrosine

(2013) Ruijiao Chen et al.   JOURNAL OF NATURAL PRODUCTS

Enantioselective Iridium-Catalyzed Hydrogenation of 3,4-Disubstituted Isoquinolines

(2012) Lei Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Studies on Direct Arylation of Pyridine N-Oxide: Evidence for Cooperative Catalysis between Two Distinct Palladium Centers

(2012) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis and cytotoxicity of (−)-jorumycin and its analogues

(2012) Wei Liu et al.   TETRAHEDRON

Meta-omic Characterization of the Marine Invertebrate Microbial Consortium That Produces the Chemotherapeutic Natural Product ET-743

(2011) Christopher M. Rath et al.   ACS Chemical Biology

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

Regioselective Reactions of Highly Substituted Arynes

(2010) Pamela M. Tadross et al.   ORGANIC LETTERS

Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem

(2009) Carmen Cuevas et al.   NATURAL PRODUCT REPORTS

Expedient synthesis of 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones via one-pot aryne acyl-alkylation/condensation

(2009) Kevin M. Allan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Total Syntheses of (−)-Renieramycin M and G and (−)-Jorumycin Using Aziridine as a Lynchpin

(2009) Yan-Chao Wu et al.   ORGANIC LETTERS

Benzothiazines in synthesis. Eight-membered ring formation in an intramolecular Friedel–Crafts reaction

(2009) Michael Harmata et al.   TETRAHEDRON LETTERS

Practical suggestions for better crystal structures

(2009) Peter Müller   Crystallography Reviews

Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks

(2008) E. M. Ocio et al.   BLOOD

Site-Selective sp2and Benzylic sp3Palladium-Catalyzed Direct Arylation

(2008) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY