Facile synthesis of chiral indolines through asymmetric hydrogenation of in situ generated indoles

A one-pot process for the enantioselective synthesis of tetrahydroquinolines and tetrahydroisoquinolines via asymmetric reductive amination (ARA)

(2018) Tao Yang et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Chiral Primary Amines by Ruthenium-Catalyzed Direct Reductive Amination of Alkyl Aryl Ketones with Ammonium Salts and Molecular H2

(2018) Xuefeng Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted-Acid-Promoted Rh-Catalyzed Asymmetric Hydrogenation of N-Unprotected Indoles: A Cocatalysis of Transition Metal and Anion Binding

(2018) Jialin Wen et al.   ORGANIC LETTERS

Enantioselective Direct Synthesis of Free Cyclic Amines via Intramolecular Reductive Amination

(2017) Ying Zhang et al.   ORGANIC LETTERS

Synthesis of chiral γ -sultams through intramolecular reductive amination with sulfonylcarbamate as N- source

(2017) Bo Song et al.   TETRAHEDRON LETTERS

Iridium-catalyzed direct asymmetric reductive amination of aromatic ketones

(2017) Haizhou Huang et al.   Organic Chemistry Frontiers

Highly Enantioselective Synthesis of Indolines: Asymmetric Hydrogenation at Ambient Temperature and Pressure with Cationic Ruthenium Diamine Catalysts

(2016) Zhusheng Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Optically Active Spirocyclic Indoline Scaffolds through an Enantioselective Reduction of Indoles

(2016) Ruediger Borrmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Hydrogenation of Unprotected Indoles Catalyzed by η6-Arene/N-Me-sulfonyldiamine–Ru(II) Complexes

(2016) Taichiro Touge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral 2,3-Disubstituted Indolines from Indoles and Aldehydes by Organocatalyzed Tandem Synthesis Involving Reduction by Trichlorosilane

(2014) Lin Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers

(2014) Victor Certal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Homogenous Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope and Mechanistic Studies

(2014) Ying Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric iridium-catalyzed hydrogenation of 2-methylindole using phosphite ligands

(2014) Sergey E. Lyubimov et al.   TETRAHEDRON LETTERS

Asymmetric hydrogenation of unprotected indoles using iridium complexes derived from P–OP ligands and (reusable) Brønsted acids

(2013) José Luis Núñez-Rico et al.   GREEN CHEMISTRY

Chiral Phosphoric Acid-Catalyzed Oxidative Kinetic Resolution of Indolines Based on Transfer Hydrogenation to Imines

(2013) Kodai Saito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Operation Deracemization of 3H-Indolines and Tetrahydroquinolines Enabled by Phase Separation

(2013) Aaron D. Lackner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective hydrogenation of N-unprotected indoles using (S)-C10–BridgePHOS as the chiral ligand

(2013) Chao Li et al.   TETRAHEDRON

New Progress and Prospects of Transition Metal-Catalyzed Asymmetric Hydrogenation

(2012) Jianhua Xie et al.   ACTA CHIMICA SINICA

Total Synthesis of Indoline Alkaloids: A Cyclopropanation Strategy

(2011) Dan Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Direct Asymmetric Hydrosilylation of Indoles: Combined Lewis Base and Brønsted Acid Activation

(2011) You-Cai Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Brønsted Acid/Pd-Complex-Promoted Tandem Reactions

(2011) Ying Duan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles

(2011) Ying Duan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Effective Asymmetric Hydrogenation of CyclicN-Alkyl Imines with Chiral Cationic Ru-MsDPEN Catalysts‡

(2011) Fei Chen et al.   ORGANIC LETTERS

Palladium-catalyzed asymmetric hydrogenation of simple ketones activated by Brønsted acids

(2011) Xiao-Yu Zhou et al.   TETRAHEDRON LETTERS

Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles

(2011) Duo-Sheng Wang et al.   Chemical Science

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium-Catalyzed Asymmetric Hydrogenation of N-Protected Indoles

(2010) Alejandro Baeza et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Brønsted Acids

(2010) Duo-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Indolines by Catalytic Enantioselective Reduction of 3H-Indoles

(2010) Magnus Rueping et al.   ORGANIC LETTERS

Enantioselective hydrogenation of indoles derivatives catalyzed by Walphos/rhodium complexes

(2010) Anna M. Maj et al.   TETRAHEDRON-ASYMMETRY

Asymmetric hydrogenation of 2-substituted N-protected-indoles catalyzed by rhodium complexes of BINOL-derived phosphoramidites

(2010) Nataša Mršić et al.   TETRAHEDRON-ASYMMETRY

Catalytic Asymmetric Hydrogenation of 5-Membered Heteroaromatics

(2009) Ryoichi Kuwano   HETEROCYCLES