Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

Origin of Enantioselectivity in the Organocatalytic Reductive Amination of α-Branched Aldehydes

(2009) Tommaso Marcelli et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Efficient and Versatile Phosphine-Phosphoramidite Ligands for Asymmetric Hydrogenation

(2009) Matthias Eggenstein et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines

(2009) Guo-Hua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Hydrogenation of N−H Imines

(2009) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

(2009) Zhi-Yong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal−Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination

(2009) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular chiral dendritic monophosphites assembled by hydrogen bonding and their use in the Rh-catalyzed asymmetric hydrogenation

(2009) Yong Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ru(II) Complexes of N-Alkylated TsDPEN Ligands in Asymmetric Transfer Hydrogenation of Ketones and Imines

(2009) José E. D. Martins et al.   ORGANIC LETTERS

New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity

(2009) Debra J. Wallace et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Remarkable Positive Effect of Silver Salts on Asymmetric Hydrogenation of Acyclic Imines with Cp*Ir Complexes Bearing Chiral N-Sulfonylated Diamine Ligands

(2009) Shin-yo Shirai et al.   ORGANOMETALLICS

Chiral 1,2,3,4-Tetrahydro-1-naphthylamine-Derived Phosphine-Phosphoramidite Ligand (THNAPhos): Application in Highly Enantioselective Hydrogenations of Functionalized CC Bonds

(2008) Min Qiu et al.   ADVANCED SYNTHESIS & CATALYSIS

Rationally-DesignedS-Chiral Bissulfinamides as Highly Enantioselective Organocatalysts for Reduction of Ketimines

(2008) Dong Pei et al.   ADVANCED SYNTHESIS & CATALYSIS

Fully Enzymatic Resolution of Chiral Amines: Acylation and Deacylation in the Presence ofCandida antarcticaLipase B

(2008) Hilda Ismail et al.   ADVANCED SYNTHESIS & CATALYSIS

The Enantioselective, Brønsted Acid Catalyzed, Vinylogous Mannich Reaction

(2008) Marcel Sickert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective CH Amination Using Cationic Ruthenium(II)-pybox Catalysts

(2008) Erika Milczek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formal Asymmetric Biocatalytic Reductive Amination

(2008) Dominik Koszelewski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Chiral β-Arylisopropylamines by Using Catalytic Asymmetric Hydrogenation

(2008) Jian Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase

(2008) Matthias Höhne et al.   CHEMBIOCHEM

Modular chiral dendritic monodentate phosphoramidite ligands for Rh(ii)-catalyzed asymmetric hydrogenation: unprecedented enhancement of enantioselectivity

(2008) Feng Zhang et al.   CHEMICAL COMMUNICATIONS

Hydroamination: Direct Addition of Amines to Alkenes and Alkynes

(2008) Thomas E. Müller et al.   CHEMICAL REVIEWS

N‐Tosyloxycarbamates as Reagents in Rhodium‐Catalyzed CH Amination Reactions

(2008) Kim Huard et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Highly Enantioselective Organocatalytic Method for Reduction of AromaticN-Alkyl Ketimines

(2008) Chao Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Marked Deuterium Isotope Effects on the Enantioselectivity in Rhodium-Catalyzed Asymmetric Hydrogenation of Enamides

(2008) Tsuneo Imamoto et al.   Chemistry-An Asian Journal

Synthesis of Enantiomerically Pure 1,2,3,4‐Tetrahydro‐β‐carbolines andN‐Acyl‐1‐aryl Ethylamines by Rhodium‐Catalyzed Hydrogenation

(2008) Stephan Enthaler et al.   Chemistry-An Asian Journal

Phosphine-Free Cp*Ru(Diamine) Catalysts in the Hydrogenation of Imines

(2008) Pradeep Cheruku et al.   Chemistry-An Asian Journal

Enantioselective catalytic reduction of ketoimines with trichlorosilane promoted by readily available chiral Lewis bases

(2008) Stefania Guizzetti et al.   CHIRALITY

A Practical and Efficient Route for the Highly Enantioselective Synthesis of Mexiletine Analogues and Novel β-Thiophenoxy and Pyridyl Ethers

(2008) Kun Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Polymer-Supported Organocatalysts: Asymmetric Reduction of Imines with Trichlorosilane Catalyzed by an Amino Acid-Derived Formamide Anchored to a Polymer†

(2008) Andrei V. Malkov et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Borane Reduction of Heteroaryl and Heterocyclic Ketoxime Ethers Catalyzed by Novel Spiroborate Ester Derived from Diphenylvalinol: Application to the Synthesis of Nicotine Analogues

(2008) Kun Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Reductive Acylation of Aromatic Ketoximes by Enzyme-Metal Cocatalysis

(2008) Kiwon Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Ytterbium Acetate Promoted Asymmetric Reductive Amination:  Significantly Enhanced Stereoselectivity

(2008) Thomas C. Nugent et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

(2008) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Hydrogenation Catalyzed by a Rhodium Complex of (R)-(tert-Butylmethylphosphino)(di-tert-butylphosphino)methane:  Scope of Enantioselectivity and Mechanistic Study

(2008) Ilya D. Gridnev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydroaminoalkylation of Unactivated Olefins with Dialkylamines

(2008) Seth B. Herzon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ag-Catalyzed Diastereo- and Enantioselective Vinylogous Mannich Reactions of α-Ketoimine Esters. Development of a Method and Investigation of its Mechanism

(2008) Laura C. Wieland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric transfer hydrogenation of imines catalyzed by a polymer-immobilized chiral catalyst

(2008) Naoki Haraguchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric reduction of ketimines with trichlorosilane employing an imidazole derived organocatalyst

(2008) François-Moana Gautier et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Axial 4,4′,6,6′-Tetrakis-trifluoromethyl-biphenyl-2,2′-diamine (TF-BIPHAM): Resolution and Applications in Asymmetric Hydrogenation

(2008) Chun-Jiang Wang et al.   ORGANIC LETTERS

An Efficient Synthesis of Enamides from Ketones

(2008) Hang Zhao et al.   ORGANIC LETTERS

Enantioselective Synthesis of Cyclic Sulfamidates via Pd-Catalyzed Hydrogenation

(2008) You-Qing Wang et al.   ORGANIC LETTERS

Synthesis of Enamides via Rh/C-Catalyzed Direct Hydroacylation of Ketoximes

(2008) Zheng-Hui Guan et al.   ORGANIC LETTERS

Stable Preformed Chiral Palladium Catalysts for the One-Pot Asymmetric Reductive Amination of Ketones

(2008) Laura Rubio-Pérez et al.   ORGANIC LETTERS

Novel chiral phosphine-phosphoramidite ligands derived from 1-naphthylamine for highly efficient Rh-catalyzed asymmetric hydrogenation

(2008) Sai-Bo Yu et al.   TETRAHEDRON-ASYMMETRY

Asymmetric synthesis of N-substituted N-hydroxyureas

(2008) Krzysztof Z. Łączkowski et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Strecker-type reaction of phosphinoyl ketimines catalyzed by a chiral Zr-bipyridyldiol catalyst

(2008) Yi-Jing Chen et al.   TETRAHEDRON-ASYMMETRY

Asymmetric reduction of aryl imines using Candida parapsilosis ATCC 7330

(2008) T. Vaijayanthi et al.   TETRAHEDRON-ASYMMETRY

Heterogeneous Raney Nickel and Cobalt Catalysts for Racemization and Dynamic Kinetic Resolution of Amines

(2007) Andrei N. Parvulescu et al.   ADVANCED SYNTHESIS & CATALYSIS

Ruthenium-catalyzed asymmetric hydrogenation of N-(3,4-dihydro-2-naphthalenyl)-acetamide

(2007) Xavier Sala et al.   CATALYSIS COMMUNICATIONS

1,2-Addition of trialkylaluminium reagents to N-diphenylphosphinoylketimines in the absence of any additional reagents

(2007) Rüdiger Reingruber et al.   CHEMICAL COMMUNICATIONS

Chiral Tertiary Diamines in Asymmetric Synthesis

(2007) Jean-Claude Kizirian   CHEMICAL REVIEWS

Iridium catalysts for the asymmetric hydrogenation of olefins with nontraditional functional substituents

(2007) Tamara L. Church et al.   COORDINATION CHEMISTRY REVIEWS

N-Isopropylsulfinylimines as Useful Intermediates in the Synthesis of Chiral Amines:  Expeditive Asymmetric Synthesis of the Calcimimetic (+)-NPS R-568

(2007) Inmaculada Fernández et al.   JOURNAL OF ORGANIC CHEMISTRY

Toward a Synthetically Useful Stereoselective C−H Amination of Hydrocarbons

(2007) Chungen Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY