标题
Lipids and Lipid Derivatives for RNA Delivery
作者
关键词
-
出版物
CHEMICAL REVIEWS
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2021-07-19
DOI
10.1021/acs.chemrev.1c00244
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles
- (2021) Uri Elia et al. ACS Nano
- Lumasiran: First Approval
- (2021) Lesley J. Scott et al. DRUGS
- First Drug Approved for Rare Genetic Disorder Affecting Kidneys
- (2021) Mary Chris Jaklevic JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
- (2021) Christina Krienke et al. SCIENCE
- Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing
- (2021) Shuai Liu et al. NATURE MATERIALS
- Neutralizing Activity of BNT162b2-Elicited Serum
- (2021) Yang Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3
- (2021) Min Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
- (2021) Linde Schoenmaker et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice
- (2021) Ruklanthi de Alwis et al. MOLECULAR THERAPY
- A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes
- (2020) Srinivas Ramishetti et al. ADVANCED MATERIALS
- Combinatorial Synthesis of a Lipidoid Library by Thiolactone Chemistry: In Vitro Screening and In Vivo Validation for siRNA Delivery
- (2020) Mijanur R. Molla et al. BIOCONJUGATE CHEMISTRY
- Givosiran: First Approval
- (2020) Lesley J. Scott DRUGS
- Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination
- (2020) Sejin Son et al. NANO LETTERS
- Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
- (2020) Margaret M. Billingsley et al. NANO LETTERS
- Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis
- (2020) Xucheng Hou et al. Nature Nanotechnology
- An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors
- (2020) Katharina Reinhard et al. SCIENCE
- Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
- (2020) Siddharth Patel et al. Nature Communications
- Lipid‐Modified Aminoglycosides for mRNA Delivery to the Liver
- (2020) Xueliang Yu et al. Advanced Healthcare Materials
- Efficient Delivery of Antisense Oligonucleotides Using Bioreducible Lipid Nanoparticles In Vitro and In Vivo
- (2020) Liu Yang et al. Molecular Therapy-Nucleic Acids
- In Vitro and In Vivo Study of Amphotericin B Formulation with Quaternized Bioreducible Lipidoids
- (2020) Fang Liu et al. ACS Biomaterials-Science & Engineering
- Tailored Lipoprotein‐Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor‐Stimulated Macropinocytosis
- (2020) Gan Jiang et al. Advanced Science
- Artificial Platelets for Efficient siRNA Delivery to Clear “Bad Cholesterol”
- (2020) Yanfen Zhang et al. ACS Applied Materials & Interfaces
- Protein and mRNA Delivery Enabled by Cholesteryl‐Based Biodegradable Lipidoid Nanoparticles
- (2020) Yamin Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Lipid Nanoparticles for Cell-Specific in Vivo Targeted Delivery of Nucleic Acids
- (2020) Ikramy A. Khalil et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- RNA-based pharmacotherapy for tumors: From bench to clinic and back
- (2020) Xiangping Liang et al. BIOMEDICINE & PHARMACOTHERAPY
- Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery
- (2020) Jeonghwan Kim et al. Cellular and Molecular Bioengineering
- Charge-reversible Lipid Derivative: A Novel Type of pH-responsive Lipid for Nanoparticle-mediated siRNA Delivery
- (2020) Yusuke Hirai et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Targeted delivery of celastrol to renal interstitial myofibroblasts using fibronectin-binding liposomes attenuates renal fibrosis and reduces systemic toxicity
- (2020) Rui Li et al. JOURNAL OF CONTROLLED RELEASE
- Hyperbranched lipoid-based lipid nanoparticles for bidirectional regulation of collagen accumulation in liver fibrosis
- (2020) Jian-Bin Qiao et al. JOURNAL OF CONTROLLED RELEASE
- Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery
- (2020) Yulia Eygeris et al. NANO LETTERS
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- RNA delivery by extracellular vesicles in mammalian cells and its applications
- (2020) Killian O’Brien et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
- (2020) Kausik K. Ray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia
- (2020) Frederick J. Raal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
- (2020) Lei Miao et al. Nature Communications
- Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles
- (2020) Jia Zhuang et al. Science Advances
- Biocompatible Nanovector of siRNA Consisting of Arginine-Based Cationic Lipid for Gene Knockdown in Cancer Cells
- (2020) Natalia Sánchez-Arribas et al. ACS Applied Materials & Interfaces
- Surface-Functionalized PEGylated Nanoparticles Deliver Messenger RNA to Pulmonary Immune Cells
- (2020) Xiyu Ke et al. ACS Applied Materials & Interfaces
- Development of lipid-like materials for RNA delivery based on intracellular environment-responsive membrane destabilization and spontaneous collapse
- (2020) Hiroki Tanaka et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipoprotein-based drug delivery
- (2020) Sara Busatto et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipid nanoparticle technology for therapeutic gene regulation in the liver
- (2020) Dominik Witzigmann et al. ADVANCED DRUG DELIVERY REVIEWS
- Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery
- (2020) Hiroki Tanaka et al. ADVANCED FUNCTIONAL MATERIALS
- Imidazole‐based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes
- (2020) Xuewei Zhao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Thermostable mRNA Vaccine against COVID-19
- (2020) Na-Na Zhang et al. CELL
- A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2
- (2020) Wanbo Tai et al. CELL RESEARCH
- DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications
- (2020) Yuhang Dong et al. CHEMICAL REVIEWS
- Magnetofection: Magic magnetic nanoparticles for efficient gene delivery
- (2020) Qunjie Bi et al. CHINESE CHEMICAL LETTERS
- Recent advances in mRNA vaccine technology
- (2020) Norbert Pardi et al. CURRENT OPINION IN IMMUNOLOGY
- A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice
- (2020) Dorottya Laczkó et al. IMMUNITY
- Nucleic acid-based drug delivery strategies
- (2020) Xuyu Tan et al. JOURNAL OF CONTROLLED RELEASE
- Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy
- (2020) Francesco Mainini et al. MOLECULES
- Role of Lipid-Based and Polymer-Based Non-Viral Vectors in Nucleic Acid Delivery for Next-Generation Gene Therapy
- (2020) Aniket Wahane et al. MOLECULES
- A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
- (2020) Khalid A. Hajj et al. NANO LETTERS
- An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
- (2020) Ugur Sahin et al. NATURE
- Advances in oligonucleotide drug delivery
- (2020) Thomas C. Roberts et al. NATURE REVIEWS DRUG DISCOVERY
- Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria
- (2020) Manisha Balwani et al. NEW ENGLAND JOURNAL OF MEDICINE
- Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
- (2020) Paul F. McKay et al. Nature Communications
- Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
- (2020) Tuo Wei et al. Nature Communications
- Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening
- (2020) Takuya Miyazaki et al. Advanced Healthcare Materials
- Characterizing Extracellular Vesicles and Their Diverse RNA Contents
- (2020) Eren M. Veziroglu et al. Frontiers in Genetics
- Co-delivery of IKBKE siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer
- (2020) Zhen Zhao et al. Science Advances
- Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection
- (2020) Feihe Ma et al. Science Advances
- A Comprehensive Review of Cancer MicroRNA Therapeutic Delivery Strategies
- (2020) Alexis Forterre et al. Cancers
- The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature
- (2020) Silvia Nuzzo et al. Cancers
- Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands
- (2020) Zubao Gan et al. Bioengineering & Translational Medicine
- Leveraging mRNA Sequences and Nanoparticles to Deliver SARS‐CoV‐2 Antigens In Vivo
- (2020) Chunxi Zeng et al. ADVANCED MATERIALS
- A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice
- (2020) Jing Lu et al. CELL RESEARCH
- PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production
- (2020) Takuya Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Triton X-100-Modified Adenosine Triphosphate-Responsive siRNA Delivery Agent for Antitumor Therapy
- (2020) Xinli Fan et al. MOLECULAR PHARMACEUTICS
- Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
- (2020) Edward E. Walsh et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults
- (2020) Evan J. Anderson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gene Therapy Based on Nucleic Acid Nanostructure
- (2020) Xiaohui Wu et al. Advanced Healthcare Materials
- Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing
- (2020) Xinfu Zhang et al. Science Advances
- Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice
- (2020) Mohammad Ariful Islam et al. BIOMATERIALS
- Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo
- (2020) Kyoko Koji et al. BIOMATERIALS
- COVID-19: A review of therapeutic strategies and vaccine candidates
- (2020) Vladislav Izda et al. CLINICAL IMMUNOLOGY
- Addressing the Cold Reality of mRNA Vaccine Stability
- (2020) Daan J.A. Crommelin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination
- (2020) Alicia T. Widge et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection
- (2020) Cole J. Batty et al. ADVANCED DRUG DELIVERY REVIEWS
- Engineered histidine-enriched facial lipopeptides for enhanced intracellular delivery of functional siRNA to triple negative breast cancer cells.
- (2019) Abhijit Biswas et al. ACS Applied Materials & Interfaces
- Bioconjugated oligonucleotides: recent developments and therapeutic applications
- (2019) sebastien benizri et al. BIOCONJUGATE CHEMISTRY
- Branched-Tail Lipid Nanoparticles Potently Deliver mRNA In Vivo due to Enhanced Ionization at Endosomal pH
- (2019) Khalid A. Hajj et al. Small
- Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
- (2019) Santiago Grijalvo et al. Pharmaceutics
- Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer
- (2019) Chengxiang Zhang et al. Nano Research
- Improved Efficacy in a Fabry Disease Model Using a Systemic mRNA Liver Depot System as Compared to Enzyme Replacement Therapy
- (2019) Frank DeRosa et al. MOLECULAR THERAPY
- Lipid-polymer hybrid nanoparticles: Synthesis strategies and biomedical applications
- (2019) Vivek Dave et al. JOURNAL OF MICROBIOLOGICAL METHODS
- Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo
- (2019) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives
- (2019) Anubhab Mukherjee et al. International Journal of Nanomedicine
- Systemic Delivery of Tumor-Targeting siRNA Nanoparticles against an Oncogenic LncRNA Facilitates Effective Triple-Negative Breast Cancer Therapy
- (2019) Amita M Vaidya et al. BIOCONJUGATE CHEMISTRY
- Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses
- (2019) Kalina Paunovska et al. ADVANCED MATERIALS
- A minimalist's approach for DNA nanoconstructions
- (2019) Hua Zuo et al. ADVANCED DRUG DELIVERY REVIEWS
- Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy
- (2019) Gulsah Erel-Akbaba et al. ACS Nano
- Lipid-mRNA Nanoparticle Designed to Enhance Intracellular Delivery Mediated by Shock Waves
- (2019) Jing Zhang et al. ACS Applied Materials & Interfaces
- Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
- (2019) Ghanbar Mahmoodi Chalbatani et al. International Journal of Nanomedicine
- Oligo(serine ester) Charge-Altering Releasable Transporters: Organocatalytic Ring-Opening Polymerization and their Use for in Vitro and in Vivo mRNA Delivery
- (2019) Nancy L. Benner et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Advances in therapeutic applications of extracellular vesicles
- (2019) Oscar P. B. Wiklander et al. Science Translational Medicine
- mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials
- (2019) Robert A. Feldman et al. VACCINE
- Formulation of Biocompatible Targeted ECO/siRNA Nanoparticles with Long-Term Stability for Clinical Translation of RNAi
- (2019) Nadia R. Ayat et al. Nucleic Acid Therapeutics
- Intriguing circles: Conflicts and controversies in circular RNA research
- (2019) Hui‐Min Li et al. Wiley Interdisciplinary Reviews-RNA
- Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
- (2019) Kimberly J. Hassett et al. Molecular Therapy-Nucleic Acids
- Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles
- (2019) Ji Liu et al. ADVANCED MATERIALS
- Nucleic‐Acid Structures as Intracellular Probes for Live Cells
- (2019) Devleena Samanta et al. ADVANCED MATERIALS
- Introduction: Nucleic Acid Nanotechnology
- (2019) Yamuna Krishnan et al. CHEMICAL REVIEWS
- Lipid-Based Vectors for Therapeutic mRNA-Based Anti-Cancer Vaccines
- (2019) Maria L Guevara et al. CURRENT PHARMACEUTICAL DESIGN
- Lipid nanoparticles for delivery of messenger RNA to the back of the eye
- (2019) Siddharth Patel et al. JOURNAL OF CONTROLLED RELEASE
- Extracellular vesicles: a new communication paradigm?
- (2019) Graça Raposo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines
- (2019) Roshan Goswami et al. ACS Infectious Diseases
- Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands
- (2019) Melissa P. Lokugamage et al. ADVANCED MATERIALS
- Development of a lipoplex-type mRNA carrier composed of an ionizable lipid with a vitamin E scaffold and the KALA peptide for use as an ex vivo dendritic cell-based cancer vaccine
- (2019) Naho Tateshita et al. JOURNAL OF CONTROLLED RELEASE
- Strategies for the use of Extracellular Vesicles for the Delivery of Therapeutics
- (2019) Susmita Sil et al. Journal of Neuroimmune Pharmacology
- A Multifunctional Lipid-Based Nanodevice for the Highly Specific Codelivery of Sorafenib and Midkine siRNA to Hepatic Cancer Cells
- (2019) Mahmoud A. Younis et al. MOLECULAR PHARMACEUTICS
- Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
- (2019) Lei Miao et al. NATURE BIOTECHNOLOGY
- Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency
- (2019) Brian Truong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted Delivery of siRNA Lipoplexes to Cancer Cells Using Macrophage Transient Horizontal Gene Transfer
- (2019) Elizabeth C. Wayne et al. Advanced Science
- Cell-Selective Messenger RNA Delivery and CRISPR/Cas9 Genome Editing by Modulating the Interface of Phenylboronic Acid-Derived Lipid Nanoparticles and Cellular Surface Sialic Acid
- (2019) Qiao Tang et al. ACS Applied Materials & Interfaces
- Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles
- (2019) Yusuke Sato et al. Acta Biomaterialia
- Mild Innate Immune Activation Overrides Efficient Nanoparticle‐Mediated RNA Delivery
- (2019) Melissa P. Lokugamage et al. ADVANCED MATERIALS
- Quantitative analysis of cholesterol oxidation products and desmosterol in parenteral liposomal pharmaceutical formulations
- (2019) Changguang Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Key determinants of siRNA delivery mediated by unique pH-responsive lipid-based liposomes
- (2019) Mariko Sako et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pharmacokinetics of Patisiran, the First Approved RNA Interference Therapy in Patients With Hereditary Transthyretin‐Mediated Amyloidosis
- (2019) Xiaoping Zhang et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application
- (2019) Adachi et al. MOLECULES
- Therapeutic Prospects of mRNA-Based Gene Therapy for Glioblastoma
- (2019) Xiangjun Tang et al. Frontiers in Oncology
- Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo
- (2019) Petro Zhupanyn et al. JOURNAL OF CONTROLLED RELEASE
- The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
- (2019) Akin Akinc et al. Nature Nanotechnology
- Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition
- (2019) Na Kong et al. Science Translational Medicine
- Strategies for the CRISPR-Based Therapeutics
- (2019) Bin Li et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Circular RNA: biogenesis, degradation, functions and potential roles in mediating resistance to anticarcinogens
- (2019) Xiuchao Geng et al. Epigenomics
- Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation
- (2019) Zhaogang Yang et al. Nature Biomedical Engineering
- On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA
- (2018) Jayesh A. Kulkarni et al. ACS Nano
- Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery
- (2018) Kalina Paunovska et al. ACS Nano
- Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems
- (2018) Masatoshi Maeki et al. ADVANCED DRUG DELIVERY REVIEWS
- One-Pot Parallel Synthesis of Lipid Library via Thiolactone Ring Opening and Screening for Gene Delivery
- (2018) Mijanur R. Molla et al. BIOCONJUGATE CHEMISTRY
- A novel Lipidoid-MicroRNA formulation promotes calvarial bone regeneration
- (2018) Lei Sui et al. BIOMATERIALS
- Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins
- (2018) Yamin Li et al. BIOMATERIALS
- Noncovalent tagging of siRNA with steroids for transmembrane delivery
- (2018) Wanyi Tai et al. BIOMATERIALS
- Paranemic Crossover DNA: There and Back Again
- (2018) Xing Wang et al. CHEMICAL REVIEWS
- Safety, tolerability, and pharmacokinetics of BMS-986263/ND-L02-s0201, a novel targeted lipid nanoparticle delivering HSP47 siRNA, in healthy participants: A randomised, placebo-controlled, double-blind, phase 1 study
- (2018) B. Soule et al. JOURNAL OF HEPATOLOGY
- Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression
- (2018) Jennifer L.S. Willoughby et al. MOLECULAR THERAPY
- Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses
- (2018) Duo Zhang et al. MOLECULAR THERAPY
- A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
- (2018) Staci Sabnis et al. MOLECULAR THERAPY
- Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation
- (2018) Shufang He et al. NANO LETTERS
- Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA
- (2018) Rebecca L. Ball et al. NANO LETTERS
- Multifunctional nucleic acid nanostructures for gene therapies
- (2018) Jianbing Liu et al. Nano Research
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
- (2018) David Adams et al. NEW ENGLAND JOURNAL OF MEDICINE
- Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
- (2018) Marianna Yanez Arteta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A review on current status of antiviral siRNA
- (2018) Abid Qureshi et al. REVIEWS IN MEDICAL VIROLOGY
- Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity
- (2018) Shinu John et al. VACCINE
- Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection
- (2018) Alvaro Baeza Garcia et al. Nature Communications
- Efficient RNA drug delivery using red blood cell extracellular vesicles
- (2018) Waqas Muhammad Usman et al. Nature Communications
- Journey of siRNA: Clinical Developments and Targeted Delivery
- (2018) Rahul R. Nikam et al. Nucleic Acid Therapeutics
- Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility
- (2018) Jayesh A. Kulkarni et al. Nucleic Acid Therapeutics
- DNA Nanostructure-Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides
- (2018) Qinqin Hu et al. Advanced Healthcare Materials
- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression
- (2018) Yanhong Guo et al. EBioMedicine
- Exosome-based small RNA delivery: Progress and prospects
- (2018) Mei Lu et al. Asian Journal of Pharmaceutical Sciences
- Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs
- (2018) Owen S. Fenton et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- PEGylated DC-Chol/DOPE cationic liposomes containing KSP siRNA as a systemic siRNA delivery Carrier for ovarian cancer therapy
- (2018) Jinju Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Immune lipoprotein nanostructures inspired relay drug delivery for amplifying antitumor efficiency
- (2018) Yue Han et al. BIOMATERIALS
- Optimization of siRNA delivery to target sites: issues and future directions
- (2018) Ikramy A. Khalil et al. Expert Opinion on Drug Delivery
- Transfection reagent Lipofectamine triggers type I interferon signaling activation in macrophages
- (2018) Xiaomin Guo et al. IMMUNOLOGY AND CELL BIOLOGY
- Tryptamine-Induced Tryptophanyl-tRNAtrp Deficiency in Neurodifferentiation and Neurodegeneration Interplay: Progenitor Activation with Neurite Growth Terminated in Alzheimer's Disease Neuronal Vesicularization and Fragmentation
- (2018) Elena L. Paley JOURNAL OF ALZHEIMERS DISEASE
- Nanoparticles Based on Poly (β-Amino Ester) and HPV16-Targeting CRISPR/shRNA as Potential Drugs for HPV16-Related Cervical Malignancy
- (2018) Da Zhu et al. MOLECULAR THERAPY
- Biomedical applications of mRNA nanomedicine
- (2018) Qingqing Xiong et al. Nano Research
- Alnylam launches era of RNAi drugs
- (2018) Ken Garber NATURE BIOTECHNOLOGY
- FDA approves landmark RNAi drug
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice
- (2018) Ole A. W. Haabeth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sugar Functionalized Synergistic Dendrimers for Biocompatible Delivery of Nucleic Acid Therapeutics
- (2018) Shuqin Han et al. Polymers
- RNA Interference as a Prospective Tool for the Control of Human Viral Infections
- (2018) Alesia Levanova et al. Frontiers in Microbiology
- Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA
- (2018) Mohammad Ariful Islam et al. Nature Biomedical Engineering
- Synthetic materials at the forefront of gene delivery
- (2018) Irene Lostalé-Seijo et al. Nature Reviews Chemistry
- Dendrimer-Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I
- (2018) Qiang Cheng et al. ADVANCED MATERIALS
- Exosomes: natural nanoparticles as bio shuttles for RNAi delivery
- (2018) Saber Ghazizadeh Darband et al. JOURNAL OF CONTROLLED RELEASE
- Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles
- (2018) Patrick Urban et al. LANGMUIR
- A Review on Electroporation-Based Intracellular Delivery
- (2018) Junfeng Shi et al. MOLECULES
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
- (2018) Cory D. Sago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
- (2018) Tia DiTommaso et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted delivery of antisense oligonucleotides to pancreatic β-cells
- (2018) C. Ämmälä et al. Science Advances
- Rigorous control of vesicle-forming lipid pKa by fluorine-conjugated bioisosteres for gene-silencing with siRNA
- (2018) Ayaka Okamoto et al. JOURNAL OF CONTROLLED RELEASE
- Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes
- (2017) Shuaijian Ni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Biodegradable lipid nanoparticles induce a prolonged RNA interference-mediated protein knockdown and show rapid hepatic clearance in mice and nonhuman primates
- (2017) Yuta Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Exosomes: Nanoparticulate tools for RNA interference and drug delivery
- (2017) Fahimeh Shahabipour et al. JOURNAL OF CELLULAR PHYSIOLOGY
- pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes
- (2017) Kazuki Hashiba et al. JOURNAL OF CONTROLLED RELEASE
- Retinal gene delivery enhancement by lycopene incorporation into cationic niosomes based on DOTMA and polysorbate 60
- (2017) Mohamed Mashal et al. JOURNAL OF CONTROLLED RELEASE
- The Delivery of Small Interfering RNA to Hepatic Stellate Cells Using a Lipid Nanoparticle Composed of a Vitamin A-Scaffold Lipid-Like Material
- (2017) Naoyuki Toriyabe et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- PEGylation of the GALA Peptide Enhances the Lung-Targeting Activity of Nanocarriers That Contain Encapsulated siRNA
- (2017) Sarochin Santiwarangkool et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Systemic delivery of complexes of melanoma RNA with mannosylated liposomes activates highly efficient murine melanoma-specific cytotoxic T cells in vivo
- (2017) O. V. Markov et al. MOLECULAR BIOLOGY
- Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques
- (2017) Frank Liang et al. MOLECULAR THERAPY
- Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer
- (2017) Jon Voutila et al. MOLECULAR THERAPY
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Adamantane in Drug Delivery Systems and Surface Recognition
- (2017) Adela Štimac et al. MOLECULES
- Cell membrane-derived nanoparticles: emerging clinical opportunities for targeted drug delivery
- (2017) Svetlana T Yurkin et al. Nanomedicine
- Cationic switchable lipids: pH-triggered molecular switch for siRNA delivery
- (2017) W. Viricel et al. Nanoscale
- Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles
- (2017) R. Krzysztoń et al. Nanoscale
- Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
- (2017) Naoki Iwamoto et al. NATURE BIOTECHNOLOGY
- Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
- (2017) Hao Yin et al. NATURE BIOTECHNOLOGY
- Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol
- (2017) Kausik K. Ray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs
- (2017) Xiulong Shen et al. NUCLEIC ACIDS RESEARCH
- Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
- (2017) James E. Dahlman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals
- (2017) Colin J. McKinlay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic delivery of factor IX messenger RNA for protein replacement therapy
- (2017) Suvasini Ramaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunogenicity and protective efficacy induced by self-amplifying mRNA vaccines encoding bacterial antigens
- (2017) Giulietta Maruggi et al. VACCINE
- Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles
- (2017) Laura I. Selby et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
- (2017) Jia-Lin Huang et al. Nature Communications
- Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
- (2017) Norbert Pardi et al. Nature Communications
- Molecular Mechanisms of Antisense Oligonucleotides
- (2017) Stanley T. Crooke Nucleic Acid Therapeutics
- Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo
- (2017) Xi Zhu et al. Theranostics
- RNA in extracellular vesicles
- (2017) Kyoung Mi Kim et al. Wiley Interdisciplinary Reviews-RNA
- Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo
- (2017) X. Luo et al. Biomaterials Science
- Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications
- (2017) Tatjana Michel et al. Molecular Therapy-Nucleic Acids
- Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing
- (2017) Yu Cao et al. Frontiers of Chemical Science and Engineering
- DNA nanotechnology
- (2017) Nadrian C. Seeman et al. Nature Reviews Materials
- High-throughput nuclear delivery and rapid expression of DNA via mechanical and electrical cell-membrane disruption
- (2017) Xiaoyun Ding et al. Nature Biomedical Engineering
- Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers
- (2017) Masatoshi Maeki et al. PLoS One
- Tumor-targeted delivery of siRNA using fatty acyl-CGKRK peptide conjugates
- (2017) Meenakshi Sharma et al. Scientific Reports
- Role of Cell Membrane–Vector Interactions in Successful Gene Delivery
- (2016) Sriram Vaidyanathan et al. ACCOUNTS OF CHEMICAL RESEARCH
- Design of Highly Potent Lipid-Functionalized Peptidomimetics for Efficient in Vivo siRNA Delivery
- (2016) Hai Xiao et al. ACS Applied Materials & Interfaces
- Efficient Cellular Knockdown Mediated by siRNA Nanovectors of Gemini Cationic Lipids Having Delocalizable Headgroups and Oligo-Oxyethylene Spacers
- (2016) María Martínez-Negro et al. ACS Applied Materials & Interfaces
- High-Density Lipoproteins: Nature’s Multifunctional Nanoparticles
- (2016) Rui Kuai et al. ACS Nano
- The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
- (2016) Xinwei Cheng et al. ADVANCED DRUG DELIVERY REVIEWS
- Properties of Native High-Density Lipoproteins Inspire Synthesis of Actively Targeted In Vivo siRNA Delivery Vehicles
- (2016) Kaylin M. McMahon et al. ADVANCED FUNCTIONAL MATERIALS
- PGMA-Based Star-Like Polycations with Plentiful Hydroxyl Groups Act as Highly Efficient miRNA Delivery Nanovectors for Effective Applications in Heart Diseases
- (2016) Rui-Quan Li et al. ADVANCED MATERIALS
- Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
- (2016) Owen S. Fenton et al. ADVANCED MATERIALS
- Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
- (2016) Jason B. Miller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Coordinative Amphiphiles as Tunable siRNA Transporters
- (2016) Jin Bum Kim et al. BIOCONJUGATE CHEMISTRY
- Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype
- (2016) Mariana Conceição et al. BIOMATERIALS
- Comparative Study of the Condensing Effects of Ergosterol and Cholesterol
- (2016) Wei-Chin Hung et al. BIOPHYSICAL JOURNAL
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
- (2016) Mercedes Tkach et al. CELL
- Lipidoid Tail Structure Strongly Influences siRNA Delivery Activity
- (2016) Christopher M. Knapp et al. Cellular and Molecular Bioengineering
- Structural studies of the formation of lipoplexes between siRNA and selected bis-imidazolium gemini surfactants
- (2016) W. Andrzejewska et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Synthesis and evaluation of novel lipopeptide as a vehicle for efficient gene delivery and gene silencing
- (2016) O.O. Koloskova et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
- (2016) F DeRosa et al. GENE THERAPY
- Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA
- (2016) Xinlong Zang et al. International Journal of Nanomedicine
- Nanomedicine engulfed by macrophages for targeted tumor therapy
- (2016) Yueqing Gu et al. International Journal of Nanomedicine
- Efficient delivery of Notch1 siRNA to SKOV3 cells by cationic cholesterol derivative-based liposome
- (2016) Yunchun Zhao et al. International Journal of Nanomedicine
- Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization
- (2016) Rebecca Ball et al. International Journal of Nanomedicine
- Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid
- (2016) Yuta Suzuki et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
- (2016) Edilberto Ojeda et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effect of particle size on their accumulation in an inflammatory lesion in a dextran sulfate sodium (DSS)-induced colitis model
- (2016) Ayaka Watanabe et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Extracellular vesicles: masters of intercellular communication and potential clinical interventions
- (2016) Jonathan M. Pitt et al. JOURNAL OF CLINICAL INVESTIGATION
- A phase Ib/IIa study of combination therapy with gemcitabine and Atu027 in patients with locally advanced or metastatic pancreatic adenocarcinoma.
- (2016) Beate Schultheis et al. JOURNAL OF CLINICAL ONCOLOGY
- A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells
- (2016) Shota Warashina et al. JOURNAL OF CONTROLLED RELEASE
- Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method
- (2016) Cyril Corbet et al. JOURNAL OF CONTROLLED RELEASE
- Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation
- (2016) Zhaogang Yang et al. JOURNAL OF CONTROLLED RELEASE
- Materials for non-viral intracellular delivery of messenger RNA therapeutics
- (2016) Kevin J. Kauffman et al. JOURNAL OF CONTROLLED RELEASE
- Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
- (2016) Sam Chen et al. JOURNAL OF CONTROLLED RELEASE
- The role of disulfide-bridge on the activities of H-shape gemini-like cationic lipid based siRNA delivery
- (2016) Xiao-Fei Ma et al. JOURNAL OF CONTROLLED RELEASE
- Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection
- (2016) Naoki Yamamoto et al. JOURNAL OF HEPATOLOGY
- Design of Ionizable Lipids To Overcome the Limiting Step of Endosomal Escape: Application in the Intracellular Delivery of mRNA, DNA, and siRNA
- (2016) Damien Habrant et al. JOURNAL OF MEDICINAL CHEMISTRY
- Effects of HMGA2 siRNA and doxorubicin dual delivery by chitosan nanoparticles on cytotoxicity and gene expression of HT-29 colorectal cancer cell line
- (2016) Homayoon Siahmansouri et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate
- (2016) Noriko Satake et al. MOLECULAR MEDICINE
- Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System
- (2016) Xiaona Jing et al. MOLECULAR PHARMACEUTICS
- Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression
- (2016) Irene C Turnbull et al. MOLECULAR THERAPY
- Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells
- (2016) Yusuke Sato et al. MOLECULAR THERAPY
- Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
- (2016) Yizhou Dong et al. NANO LETTERS
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- Biodistribution and pharmacokinetics ofMad2siRNA-loaded EGFR-targeted chitosan nanoparticles in cisplatin sensitive and resistant lung cancer models
- (2016) Ana Vanessa Nascimento et al. Nanomedicine
- Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines
- (2016) Thomas Démoulins et al. Nanomedicine-Nanotechnology Biology and Medicine
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
- (2016) Yang Yang et al. NATURE BIOTECHNOLOGY
- Lipid Nanoparticles Loaded with an Antisense Oligonucleotide Gapmer Against Bcl-2 for Treatment of Lung Cancer
- (2016) Xinwei Cheng et al. PHARMACEUTICAL RESEARCH
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
- (2016) Ming Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells
- (2016) Yunfeng Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
- (2016) Kejin Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Looking Beyond Structure: Membrane Phospholipids of Skeletal Muscle Mitochondria
- (2016) Timothy D. Heden et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia
- (2016) Joseph F. Nabhan et al. Scientific Reports
- Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy
- (2016) Jinju Lee et al. Theranostics
- Targeted Dual pH-Sensitive Lipid ECO/siRNA Self-Assembly Nanoparticles Facilitate In Vivo Cytosolic sieIF4E Delivery and Overcome Paclitaxel Resistance in Breast Cancer Therapy
- (2016) Maneesh Gujrati et al. Advanced Healthcare Materials
- Exosome-mediated small RNA delivery for gene therapy
- (2016) Yu Zhou et al. Wiley Interdisciplinary Reviews-RNA
- Enhanced siRNA delivery of a cyclododecylated dendrimer compared to its linear derivative
- (2016) Wanwan Shen et al. Journal of Materials Chemistry B
- Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
- (2016) Dinh Ha et al. Acta Pharmaceutica Sinica B
- Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA
- (2016) Bin Li et al. Scientific Reports
- siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes
- (2015) Shigeo Matsuda et al. ACS Chemical Biology
- Stealth monoolein-based nanocarriers for delivery of siRNA to cancer cells
- (2015) Ana C.N. Oliveira et al. Acta Biomaterialia
- In vivo delivery of miRNAs for cancer therapy: Challenges and strategies
- (2015) Yunching Chen et al. ADVANCED DRUG DELIVERY REVIEWS
- Preclinical and clinical development of siRNA-based therapeutics
- (2015) Gulnihal Ozcan et al. ADVANCED DRUG DELIVERY REVIEWS
- Antisense oligonucleotides in therapy for neurodegenerative disorders
- (2015) Melvin M. Evers et al. ADVANCED DRUG DELIVERY REVIEWS
- Switchable Lipids: Conformational Change for Fast pH-Triggered Cytoplasmic Delivery
- (2015) Warren Viricel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biodegradable Stearylated Peptide with Internal Disulfide Bonds for Efficient Delivery of siRNA In Vitro and In Vivo
- (2015) Zongguang Tai et al. BIOMACROMOLECULES
- Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer
- (2015) Jenny G. Parvani et al. CANCER RESEARCH
- pH-Cleavable Nucleoside Lipids: A New Paradigm for Controlling the Stability of Lipid-Based Delivery Systems
- (2015) Khalid Oumzil et al. ChemMedChem
- Lipid-Based Nanocarriers for RNA Delivery
- (2015) Hui Xue et al. CURRENT PHARMACEUTICAL DESIGN
- Fatty acid modified octa-arginine for delivery of siRNA
- (2015) Yuhuan Li et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model
- (2015) Oleg V. Markov et al. JOURNAL OF CONTROLLED RELEASE
- A neutral lipid envelope-type nanoparticle composed of a pH-activated and vitamin E-scaffold lipid-like material as a platform for a gene carrier targeting renal cell carcinoma
- (2015) Hidetaka Akita et al. JOURNAL OF CONTROLLED RELEASE
- siRNA-lipid nanoparticles with long-term storage stability facilitate potent gene-silencing in vivo
- (2015) Y. Suzuki et al. JOURNAL OF CONTROLLED RELEASE
- siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes
- (2015) Yoshiyuki Hattori et al. JOURNAL OF LIPOSOME RESEARCH
- Rapid Synthesis of a Lipocationic Polyester Library via Ring-Opening Polymerization of Functional Valerolactones for Efficacious siRNA Delivery
- (2015) Jing Hao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
- (2015) Michela Brazzoli et al. JOURNAL OF VIROLOGY
- Lipid–PEG Conjugates Sterically Stabilize and Reduce the Toxicity of Phytantriol-Based Lyotropic Liquid Crystalline Nanoparticles
- (2015) Jiali Zhai et al. LANGMUIR
- mRNA: Fulfilling the Promise of Gene Therapy
- (2015) Drew Weissman et al. MOLECULAR THERAPY
- Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature
- (2015) Omar F. Khan et al. NANO LETTERS
- An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo
- (2015) Bin Li et al. NANO LETTERS
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications
- (2015) Sarah Altınoglu et al. Nanomedicine
- Nanoparticle biointerfacing by platelet membrane cloaking
- (2015) Che-Ming J. Hu et al. NATURE
- Gene therapy returns to centre stage
- (2015) Luigi Naldini NATURE
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- Clinical experiences with systemically administered siRNA-based therapeutics in cancer
- (2015) Jonathan E. Zuckerman et al. NATURE REVIEWS DRUG DISCOVERY
- Knocking down disease: a progress report on siRNA therapeutics
- (2015) Anders Wittrup et al. NATURE REVIEWS GENETICS
- Programmable materials and the nature of the DNA bond
- (2015) M. R. Jones et al. SCIENCE
- Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy
- (2015) C. Long et al. SCIENCE
- Supramolecularly engineered phospholipids constructed by nucleobase molecular recognition: upgraded generation of phospholipids for drug delivery
- (2015) Dali Wang et al. Chemical Science
- Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells
- (2015) Jean-Rémi Bertrand et al. Nucleic Acid Therapeutics
- Cell or Cell Membrane-Based Drug Delivery Systems
- (2015) Songwei Tan et al. Theranostics
- Synthesis, Physicochemical Characterization, and Interaction with DNA of Long-Alkyl-Chain Gemini Pyridinium Surfactants
- (2015) Nadia Barbero et al. ChemPlusChem
- Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
- (2015) Britta Vallazza et al. Wiley Interdisciplinary Reviews-RNA
- Chimeric Antisense Oligonucleotide Conjugated to α-Tocopherol
- (2015) Tomoko Nishina et al. Molecular Therapy-Nucleic Acids
- Molecular Tuning of a Vitamin E-Scaffold pH-Sensitive and Reductive Cleavable Lipid-like Material for Accelerated in Vivo Hepatic siRNA Delivery
- (2015) Hidetaka Akita et al. ACS Biomaterials-Science & Engineering
- Influence of cholesterol on liposome stability and on in vitro drug release
- (2015) Maria-Lucia Briuglia et al. Drug Delivery and Translational Research
- Molecular Tuning of a Vitamin E-Scaffold pH-Sensitive and Reductive Cleavable Lipid-like Material for Accelerated in Vivo Hepatic siRNA Delivery
- (2015) Hidetaka Akita et al. ACS Biomaterials Science & Engineering
- CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation
- (2015) X. Han et al. Science Advances
- Cell-Type–Specific Aptamer and Aptamer-Small Interfering RNA Conjugates for Targeted Human Immunodeficiency Virus Type 1 Therapy
- (2015) Jiehua Zhou et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
- (2015) Rebecca L. Ball et al. PLoS One
- Gemini Surfactants Based on Bis-Imidazolium Alkoxy Derivatives as Effective Agents for Delivery of Nucleic Acids: A Structural and Spectroscopic Study
- (2015) Zuzanna Pietralik et al. PLoS One
- Dioctadecyldimethylammonium:Monoolein Nanocarriers for Efficient in Vitro Gene Silencing
- (2014) Ana Cristina Norberto Oliveira et al. ACS Applied Materials & Interfaces
- Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles
- (2014) Kirill A. Afonin et al. ACS Nano
- Liposomal siRNA nanocarriers for cancer therapy
- (2014) Bulent Ozpolat et al. ADVANCED DRUG DELIVERY REVIEWS
- Ionizable Amphiphilic Dendrimer-Based Nanomaterials with Alkyl-Chain-Substituted Amines for Tunable siRNA Delivery to the Liver Endothelium In Vivo
- (2014) Omar F. Khan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Combinatorially Designed Lipid-like Nanoparticles for Intracellular Delivery of Cytotoxic Protein for Cancer Therapy
- (2014) Ming Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Electroporation-Based Technologies for Medicine: Principles, Applications, and Challenges
- (2014) Martin L. Yarmush et al. Annual Review of Biomedical Engineering
- Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
- (2014) Selma Maric et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics
- (2014) Gijs Koopmanschap et al. Beilstein Journal of Organic Chemistry
- Structural dynamics and physicochemical properties of pDNA/DODAB:MO lipoplexes: Effect of pH and anionic lipids in inverted non-lamellar phases versus lamellar phases
- (2014) J.P. Neves Silva et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy
- (2014) Kasper Bendix Johnsen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Direct cytosolic siRNA delivery by reconstituted high density lipoprotein for target-specific therapy of tumor angiogenesis
- (2014) Yang Ding et al. BIOMATERIALS
- Low-density lipoprotein-coupled N-succinyl chitosan nanoparticles co-delivering siRNA and doxorubicin for hepatocyte-targeted therapy
- (2014) Qiao-ling Zhu et al. BIOMATERIALS
- Sialic Acids Sweeten a Tumor's Life
- (2014) C. Bull et al. CANCER RESEARCH
- Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing
- (2014) Qiurong Ding et al. CIRCULATION RESEARCH
- Lipid-based mRNA vaccine delivery systems
- (2014) Patrick Midoux et al. Expert Review of Vaccines
- VCAM-1 specific PEGylated SAINT-based lipoplexes deliver siRNA to activated endothelium in vivo but do not attenuate target gene expression
- (2014) Niek G.J. Leus et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- First-in-Human Phase I Study of the Liposomal RNA Interference Therapeutic Atu027 in Patients With Advanced Solid Tumors
- (2014) Beate Schultheis et al. JOURNAL OF CLINICAL ONCOLOGY
- How does spacer length of imidazolium gemini surfactants control the fabrication of 2D-Langmuir films of silver-nanoparticles at the air–water interface?
- (2014) Sougata Datta et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Designer lipids for drug delivery: From heads to tails
- (2014) Aditya G. Kohli et al. JOURNAL OF CONTROLLED RELEASE
- Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo
- (2014) Piotr S. Kowalski et al. JOURNAL OF CONTROLLED RELEASE
- Target-specific delivery of siRNA by stabilized calcium phosphate nanoparticles using dopa–hyaluronic acid conjugate
- (2014) Min Sang Lee et al. JOURNAL OF CONTROLLED RELEASE
- Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion
- (2014) W. M. Bogers et al. JOURNAL OF INFECTIOUS DISEASES
- Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing
- (2014) Jayaprakash K. Nair et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Lies and deception in bacterial gene regulation: the roles of nucleic acid decoys
- (2014) Yvonne Göpel et al. MOLECULAR MICROBIOLOGY
- Stabilization of Ostwald Ripening in Low Molecular Weight Amino Lipid Nanoparticles for Systemic Delivery of siRNA Therapeutics
- (2014) Marian E. Gindy et al. MOLECULAR PHARMACEUTICS
- Multifunctional Cationic Lipid-Based Nanoparticles Facilitate Endosomal Escape and Reduction-Triggered Cytosolic siRNA Release
- (2014) Maneesh Gujrati et al. MOLECULAR PHARMACEUTICS
- A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines
- (2014) Luis A Brito et al. MOLECULAR THERAPY
- Intracellular delivery of nanomaterials: How to catch endosomal escape in the act
- (2014) Thomas F. Martens et al. Nano Today
- Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
- (2014) Hao Yin et al. NATURE BIOTECHNOLOGY
- In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight
- (2014) James E. Dahlman et al. Nature Nanotechnology
- mRNA-based therapeutics — developing a new class of drugs
- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Antisense Oligonucleotides Capable of Promoting Specific Target mRNA Reduction via Competing RNase H1-Dependent and Independent Mechanisms
- (2014) Timothy A. Vickers et al. PLoS One
- Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
- (2014) Y. Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes
- (2014) J. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
- (2014) Kathryn A. Whitehead et al. Nature Communications
- Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
- (2014) Fritz Eckstein Nucleic Acid Therapeutics
- In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.
- (2014) Tsunamasa Watanabe et al. Scientific Reports
- Enhanced Intracellular siRNA Delivery using Bioreducible Lipid-Like Nanoparticles
- (2014) Ming Wang et al. Advanced Healthcare Materials
- Neutralized Nanoparticle Composed of SS-Cleavable and pH-Activated Lipid-Like Material as a Long-Lasting and Liver-Specific Gene Delivery System
- (2014) Masami Ukawa et al. Advanced Healthcare Materials
- Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo
- (2014) Yizhou Dong et al. Advanced Healthcare Materials
- Tamoxifen embedded in lipid bilayer improves the oncotarget of liposomal daunorubicin in vivo
- (2014) M. H. Li et al. Journal of Materials Chemistry B
- Cationic gemini lipids containing polyoxyethylene spacers as improved transfecting agents of plasmid DNA in cancer cells
- (2014) Ana L. Barrán-Berdón et al. Journal of Materials Chemistry B
- Mechanism of Polyplex- and Lipoplex-Mediated Delivery of Nucleic Acids: Real-Time Visualization of Transient Membrane Destabilization without Endosomal Lysis
- (2013) Zia ur Rehman et al. ACS Nano
- Stable RNA nanoparticles as potential new generation drugs for cancer therapy
- (2013) Yi Shu et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery
- (2013) Yunlong Zhang et al. ADVANCED MATERIALS
- The Headgroup Evolution of Cationic Lipids for Gene Delivery
- (2013) Defu Zhi et al. BIOCONJUGATE CHEMISTRY
- The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors
- (2013) Hiroto Hatakeyama et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy
- (2013) Yuan Zhang et al. BIOMATERIALS
- Interfacial engineering of pyridinium gemini surfactants for the generation of synthetic transfection systems
- (2013) Vishnu D. Sharma et al. BIOMATERIALS
- Core-Shell type lipid/rPAA-Chol polymer hybrid nanoparticles for in vivo siRNA delivery
- (2013) Ling-Yan Gao et al. BIOMATERIALS
- Gene therapy for cardiovascular disease mediated by ultrasound and microbubbles
- (2013) Zhi-Yi Chen et al. Cardiovascular Ultrasound
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Phospholipid-Detergent Conjugates as Novel Tools for siRNA Delivery
- (2013) Philippe Pierrat et al. CHEMISTRY-A EUROPEAN JOURNAL
- In-Vivo Gene Delivery by Sonoporation: Recent Progress and Prospects
- (2013) Jean-Michel Escoffre et al. CURRENT GENE THERAPY
- Cholesterol precursors
- (2013) Andrew J. Brown et al. CURRENT OPINION IN LIPIDOLOGY
- An efficient method for long-term room temperature storage of RNA
- (2013) Anne-Lise Fabre et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection
- (2013) Cristine Gonçalves et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations
- (2013) Xinmei Wang et al. JOURNAL OF CONTROLLED RELEASE
- Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA
- (2013) Oleh Taratula et al. JOURNAL OF CONTROLLED RELEASE
- Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery
- (2013) Anthony S. Malamas et al. JOURNAL OF CONTROLLED RELEASE
- Efficient delivery of therapeutic small nucleic acids to prostate cancer cells using ketal nucleoside lipid nanoparticles
- (2013) Delphine Luvino et al. JOURNAL OF CONTROLLED RELEASE
- A novel cationic niosome formulation for gene delivery to the retina
- (2013) G. Puras et al. JOURNAL OF CONTROLLED RELEASE
- Dual-Responsive Surfaces Modified with Phenylboronic Acid-Containing Polymer Brush To Reversibly Capture and Release Cancer Cells
- (2013) Hongliang Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Developing Lipid Nanoparticle-Based siRNA Therapeutics for Hepatocellular Carcinoma Using an Integrated Approach
- (2013) Leiming Li et al. MOLECULAR CANCER THERAPEUTICS
- Anti-VCAM-1 and Anti-E-selectin SAINT-O-Somes for Selective Delivery of siRNA into Inflammation-Activated Primary Endothelial Cells
- (2013) Piotr S. Kowalski et al. MOLECULAR PHARMACEUTICS
- Stabilization of Distearoylphosphatidylcholine Lamellar Phases in Propylene Glycol Using Cholesterol
- (2013) Richard D. Harvey et al. MOLECULAR PHARMACEUTICS
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
- (2013) Martin A Maier et al. MOLECULAR THERAPY
- Gene Silencing via RNAi and siRNA Quantification in Tumor Tissue Using MEND, a Liposomal siRNA Delivery System
- (2013) Yu Sakurai et al. MOLECULAR THERAPY
- Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor
- (2013) Shu-hao Hsu et al. Nanomedicine-Nanotechnology Biology and Medicine
- Phospholipid-modified polyethylenimine-based nanopreparations for siRNA–mediated gene silencing: Implications for transfection and the role of lipid components
- (2013) Gemma Navarro et al. Nanomedicine-Nanotechnology Biology and Medicine
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
- (2013) Lior Zangi et al. NATURE BIOTECHNOLOGY
- Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
- (2013) Gaurav Sahay et al. NATURE BIOTECHNOLOGY
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Extracellular vesicles: biology and emerging therapeutic opportunities
- (2013) Samir EL Andaloussi et al. NATURE REVIEWS DRUG DISCOVERY
- Rat Brain-Uptake Index for Phenylethylamine and Various Monomethylated Derivatives
- (2013) Aron D. Mosnaim et al. NEUROCHEMICAL RESEARCH
- Structure–transfection activity relationships in a series of novel cationic lipids with heterocyclic head-groups
- (2013) Ekaterina A. Ivanova et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA
- (2013) Philippe Pierrat et al. PHARMACEUTICAL RESEARCH
- Transfection and structural properties of phytanyl substituted gemini surfactant-based vectors for gene delivery
- (2013) Haitang Wang et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
- (2013) C. A. Alabi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug
- (2013) X. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A vector-free microfluidic platform for intracellular delivery
- (2013) A. Sharei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Based Tools for Nuclear Reprogramming and Lineage-Conversion: Towards Clinical Applications
- (2013) Juan A. Bernal Journal of Cardiovascular Translational Research
- A Neutral Envelope-Type Nanoparticle Containing pH-Responsive and SS-Cleavable Lipid-Like Material as a Carrier for Plasmid DNA
- (2013) Hidetaka Akita et al. Advanced Healthcare Materials
- Delivery of RNA and Its Intracellular Translation into Protein Mediated by SDS-CTAB Vesicles: Potential Use in Nanobiotechnology
- (2013) Laura Russo et al. Biomed Research International
- Magnetofection: A Reproducible Method for Gene Delivery to Melanoma Cells
- (2013) Lara Prosen et al. Biomed Research International
- Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
- (2013) Armon Sharei et al. Jove-Journal of Visualized Experiments
- Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles
- (2013) Barbara L Mui et al. Molecular Therapy-Nucleic Acids
- Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain
- (2013) Ravi L Rungta et al. Molecular Therapy-Nucleic Acids
- Lipid nanoparticle delivery systems for siRNA-based therapeutics
- (2013) C. Wan et al. Drug Delivery and Translational Research
- Advances in Lipid Nanoparticles for siRNA Delivery
- (2013) Yuen Tam et al. Pharmaceutics
- Safety profile of RNAi nanomedicines
- (2012) Scott A. Barros et al. ADVANCED DRUG DELIVERY REVIEWS
- Cationic lipids activate intracellular signaling pathways
- (2012) Caroline Lonez et al. ADVANCED DRUG DELIVERY REVIEWS
- Liposomal drug delivery systems: From concept to clinical applications
- (2012) Theresa M. Allen et al. ADVANCED DRUG DELIVERY REVIEWS
- Exosomes for targeted siRNA delivery across biological barriers
- (2012) Samir EL Andaloussi et al. ADVANCED DRUG DELIVERY REVIEWS
- Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
- (2012) Fangqiong Tang et al. ADVANCED MATERIALS
- An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo
- (2012) Tianzhu Yu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Transfection efficiency boost of cholesterol-containing lipoplexes
- (2012) Daniela Pozzi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine
- (2012) Shinichi Mochizuki et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Synthesis, Characterization, and Evaluation of Ionizable Lysine-Based Lipids for siRNA Delivery
- (2012) Colin L. Walsh et al. BIOCONJUGATE CHEMISTRY
- How Does the Spacer Length of Cationic Gemini Lipids Influence the Lipoplex Formation with Plasmid DNA? Physicochemical and Biochemical Characterizations and their Relevance in Gene Therapy
- (2012) Mónica Muñoz-Úbeda et al. BIOMACROMOLECULES
- A biomimetic lipid library for gene delivery through thiol-yne click chemistry
- (2012) Linxian Li et al. BIOMATERIALS
- Lipid nanoparticles for hepatic delivery of small interfering RNA
- (2012) Bo Yu et al. BIOMATERIALS
- Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties
- (2012) Colin L. Walsh et al. CHEMICAL COMMUNICATIONS
- Efficient and safe delivery of siRNA using anionic lipids: Formulation optimization studies
- (2012) Mamta Kapoor et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo
- (2012) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- Doxil® — The first FDA-approved nano-drug: Lessons learned
- (2012) Yechezkel (Chezy) Barenholz JOURNAL OF CONTROLLED RELEASE
- How cationic lipids transfer nucleic acids into cells and across cellular membranes: Recent advances
- (2012) Zia ur Rehman et al. JOURNAL OF CONTROLLED RELEASE
- The mannose receptor
- (2012) Luisa Martinez-Pomares JOURNAL OF LEUKOCYTE BIOLOGY
- Small-Angle Neutron-Scattering Studies of Mixed Micellar Structures Made of Dimeric Surfactants Having Imidazolium and Ammonium Headgroups
- (2012) Asish Pal et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation
- (2012) Delai Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pendant Polymer:Amino-β-Cyclodextrin:siRNA Guest:Host Nanoparticles as Efficient Vectors for Gene Silencing
- (2012) Aditya Kulkarni et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Gemini Imidazolium Surfactants: Synthesis and Their Biophysiochemical Study
- (2012) Raman Kamboj et al. LANGMUIR
- Heterocyclic Cationic Gemini Surfactants: A Comparative Overview of Their Synthesis, Self-assembling, Physicochemical, and Biological Properties
- (2012) Vishnu Dutt Sharma et al. MEDICINAL RESEARCH REVIEWS
- Asymmetrical N4,N9-Diacyl Spermines: SAR Studies of Nonviral Lipopolyamine Vectors for Efficient siRNA Delivery with Silencing of EGFP Reporter Gene
- (2012) Ian S. Blagbrough et al. MOLECULAR PHARMACEUTICS
- Glycerol Monooleate-Based Nanocarriers for siRNA Delivery in Vitro
- (2012) Guoliang Zhen et al. MOLECULAR PHARMACEUTICS
- Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids
- (2012) Michael D. Pungente et al. MOLECULES
- Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA
- (2012) Paulo J.C. Lin et al. Nanomedicine-Nanotechnology Biology and Medicine
- RNA therapeutics: beyond RNA interference and antisense oligonucleotides
- (2012) Ryszard Kole et al. NATURE REVIEWS DRUG DISCOVERY
- Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
- (2012) Jessica Wahlgren et al. NUCLEIC ACIDS RESEARCH
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Exploiting cell surface thiols to enhance cellular uptake
- (2012) Adrian G. Torres et al. TRENDS IN BIOTECHNOLOGY
- DODAB:monoolein-based lipoplexes as non-viral vectors for transfection of mammalian cells
- (2011) J.P. Neves Silva et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A Molecular Umbrella Approach to the Intracellular Delivery of Small Interfering RNA
- (2011) Lauren L. Cline et al. BIOCONJUGATE CHEMISTRY
- Dicetyl Phosphate-Tetraethylenepentamine-Based Liposomes for Systemic siRNA Delivery
- (2011) Tomohiro Asai et al. BIOCONJUGATE CHEMISTRY
- Mechanistic Insights into LDL Nanoparticle-Mediated siRNA Delivery
- (2011) Honglin Jin et al. BIOCONJUGATE CHEMISTRY
- Galactose-Modified Cationic Liposomes as a Liver-Targeting Delivery System for Small Interfering RNA
- (2011) Satoru Sonoke et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA
- (2011) Rae Sung Chang et al. BIOMATERIALS
- The many faces of the adamantyl group in drug design
- (2011) Joe Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- MicroRNA therapeutics
- (2011) J A Broderick et al. GENE THERAPY
- Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
- (2011) Justin B. Lee et al. INTERNATIONAL JOURNAL OF CANCER
- Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells
- (2011) Cheng-Wei Chen et al. International Journal of Nanomedicine
- Design of multifunctional non-viral gene vectors to overcome physiological barriers: Dilemmas and strategies
- (2011) Tao Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor
- (2011) Jun Li et al. JOURNAL OF CONTROLLED RELEASE
- Interaction of Cholesterol-Conjugated Ionizable Amino Lipids with Biomembranes: Lipid Polymorphism, Structure–Activity Relationship, and Implications for siRNA Delivery
- (2011) Jingtao Zhang et al. LANGMUIR
- Nanogyroids Incorporating Multivalent Lipids: Enhanced Membrane Charge Density and Pore Forming Ability for Gene Silencing
- (2011) Cecília Leal et al. LANGMUIR
- Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid pKaon Cationic Lipid−Biomembrane Interactions
- (2011) Jingtao Zhang et al. LANGMUIR
- SPANosomes as Delivery Vehicles for Small Interfering RNA (siRNA)
- (2011) Chenguang Zhou et al. MOLECULAR PHARMACEUTICS
- Mannose-Functionalized “Pathogen-like” Polyanhydride Nanoparticles Target C-Type Lectin Receptors on Dendritic Cells
- (2011) Brenda Carrillo-Conde et al. MOLECULAR PHARMACEUTICS
- In Vitroandin VivomRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
- (2011) Xingfang Su et al. MOLECULAR PHARMACEUTICS
- Efficient Silencing of EGFP Reporter Gene with siRNA Delivered by Asymmetrical N4,N9-Diacyl Spermines
- (2011) Abdelkader A. Metwally et al. MOLECULAR PHARMACEUTICS
- Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells
- (2011) Genc Basha et al. MOLECULAR THERAPY
- An Amino Acid-based Amphoteric Liposomal Delivery System for Systemic Administration of siRNA
- (2011) Roger C Adami et al. MOLECULAR THERAPY
- Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice
- (2011) Phong Trang et al. MOLECULAR THERAPY
- Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
- (2011) Federico Perche et al. Nanomedicine-Nanotechnology Biology and Medicine
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Photoporation of Biomolecules into Single Cells in Living Vertebrate Embryos Induced by a Femtosecond Laser Amplifier
- (2011) Yoichiroh Hosokawa et al. PLoS One
- Efficient Cytosolic Delivery of siRNA Using HDL-Mimicking Nanoparticles
- (2011) Mi Yang et al. Small
- Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
- (2011) Feng Zhao et al. Small
- Enhanced Chemotherapy Efficacy by Sequential Delivery of siRNA and Anticancer Drugs Using PEI-Grafted Graphene Oxide
- (2011) Liming Zhang et al. Small
- Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
- (2011) María Mittelbrunn et al. Nature Communications
- Polymers in Small-Interfering RNA Delivery
- (2011) Kaushik Singha et al. Nucleic Acid Therapeutics
- Efficient Gene Silencing by Self-Assembled Complexes of siRNA and Symmetrical Fatty Acid Amides of Spermine
- (2011) Abdelkader A. Metwally et al. Pharmaceutics
- Self-Assembled Lipoplexes of Short Interfering RNA (siRNA) Using Spermine-Based Fatty Acid Amide Guanidines: Effect on Gene Silencing Efficiency
- (2011) Abdelkader A. Metwally et al. Pharmaceutics
- Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy
- (2010) Morteza Mahmoudi et al. ADVANCED DRUG DELIVERY REVIEWS
- Assessment of Tumor Metastasis by the Direct Determination of Cell-Membrane Sialic Acid Expression
- (2010) Akira Matsumoto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Thiol-Yne Chemistry: A Powerful Tool for Creating Highly Functional Materials
- (2010) Richard Hoogenboom ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
- (2010) C. Frank Bennett et al. Annual Review of Pharmacology and Toxicology
- Plant pentacyclic triterpenic acids as modulators of lipid membrane physical properties
- (2010) Jesús Prades et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery
- (2010) Kerry P. Mahon et al. BIOCONJUGATE CHEMISTRY
- Transfection Efficiency of Cationic Lipids with Different Hydrophobic Domains in Gene Delivery
- (2010) DeFu Zhi et al. BIOCONJUGATE CHEMISTRY
- Cationic Nucleoside Lipids Derived from Universal Bases: A Rational Approach for siRNA Transfection
- (2010) Claire Ceballos et al. BIOCONJUGATE CHEMISTRY
- The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation
- (2010) Ranit Kedmi et al. BIOMATERIALS
- Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions
- (2010) Megan M. Kaneda et al. BIOMATERIALS
- Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34
- (2010) J. F. Wiggins et al. CANCER RESEARCH
- Synthesis and delivery activity of new cationic cholesteryl glucosides
- (2010) Mikhail A. Maslov et al. CARBOHYDRATE RESEARCH
- Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models
- (2010) A. Santel et al. CLINICAL CANCER RESEARCH
- Gene delivery by lipoplexes and polyplexes
- (2010) Conchita Tros de Ilarduya et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- DC-Chol/DOPE cationic liposomes: A comparative study of the influence factors on plasmid pDNA and siRNA gene delivery
- (2010) Yang Zhang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Multifunctional Nanoparticles Delivering Small Interfering RNA and Doxorubicin Overcome Drug Resistance in Cancer
- (2010) Yunching Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endosomal escape pathways for delivery of biologicals
- (2010) Amir K. Varkouhi et al. JOURNAL OF CONTROLLED RELEASE
- Glioma-initiating cells: A predominant role in microglia/macrophages tropism to glioma
- (2010) Liang Yi et al. JOURNAL OF NEUROIMMUNOLOGY
- Highly Efficient Gene Silencing Activity of siRNA Embedded in a Nanostructured Gyroid Cubic Lipid Matrix
- (2010) Cecília Leal et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Tailoring Lipoplex Composition to the Lipid Composition of Plasma Membrane: A Trojan Horse for Cell Entry?
- (2010) Cristina Marchini et al. LANGMUIR
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver
- (2010) Weikang Tao et al. MOLECULAR THERAPY
- Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses
- (2010) Weikang Tao et al. MOLECULAR THERAPY
- Polymer- and lipid-based nanoparticle therapeutics for the treatment of liver diseases
- (2010) Lanjuan Li et al. Nano Today
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- The emerging field of RNA nanotechnology
- (2010) Peixuan Guo Nature Nanotechnology
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional delivery of viral miRNAs via exosomes
- (2010) D. M. Pegtel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Locked nucleic acid as a novel class of therapeutic agents
- (2010) Rakesh N. Veedu et al. RNA Biology
- Platelet-derived microparticles – an updated perspective
- (2010) Pia R.M. Siljander THROMBOSIS RESEARCH
- Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells
- (2010) Mohd Javed Akhtar et al. TOXICOLOGY
- Laser-Activated Gene Silencing via Gold Nanoshell−siRNA Conjugates
- (2009) Gary B. Braun et al. ACS Nano
- Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs
- (2009) Tian Xia et al. ACS Nano
- Lipid-Like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells
- (2009) Seung-Woo Cho et al. ADVANCED FUNCTIONAL MATERIALS
- All-in-One Target-Cell-Specific Magnetic Nanoparticles for Simultaneous Molecular Imaging and siRNA Delivery
- (2009) Jae-Hyun Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ligand-Targeted Delivery of Small Interfering RNAs to Malignant Cells and Tissues
- (2009) Mini Thomas et al. Annals of the New York Academy of Sciences
- Cationic Nucleoside Lipids Based on a 3-Nitropyrrole Universal Base for siRNA Delivery
- (2009) Claire Ceballos et al. BIOCONJUGATE CHEMISTRY
- Addressing the problem of cationic lipid-mediated toxicity: The magnetoliposome model
- (2009) Stefaan J.H. Soenen et al. BIOMATERIALS
- A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation
- (2009) X. Zheng et al. BLOOD
- A modified protocol for efficient DNA encapsulation into pegylated immunoliposomes (PILs)
- (2009) Tina Skjørringe et al. JOURNAL OF CONTROLLED RELEASE
- Anionic amino acid-derived cationic lipid for siRNA delivery
- (2009) Min Sung Suh et al. JOURNAL OF CONTROLLED RELEASE
- DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA
- (2009) Mathieu Mével et al. JOURNAL OF CONTROLLED RELEASE
- Noninvasive Sialic Acid Detection at Cell Membrane by Using Phenylboronic Acid Modified Self-Assembled Monolayer Gold Electrode
- (2009) Akira Matsumoto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mesomorphic Imidazolium Salts: New Vectors for Efficient siRNA Transfection
- (2009) William Dobbs et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates
- (2009) David A. Giljohann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Novel Gemini Pyridinium Surfactants: Synthesis and Study of Their Surface Activity, DNA Binding, and Cytotoxicity
- (2009) Avinash Bhadani et al. LANGMUIR
- Novel Cationic Lipid That Delivers siRNA and Enhances Therapeutic Effect in Lung Cancer Cells
- (2009) Yunching Chen et al. MOLECULAR PHARMACEUTICS
- A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery
- (2009) James J. Lu et al. MOLECULAR PHARMACEUTICS
- Drug Delivery–mediated Control of RNA Immunostimulation
- (2009) David N. Nguyen et al. MOLECULAR THERAPY
- Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
- (2009) Akin Akinc et al. MOLECULAR THERAPY
- Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment
- (2009) Marc T Abrams et al. MOLECULAR THERAPY
- Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein
- (2009) Akiko Eguchi et al. NATURE BIOTECHNOLOGY
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Sensors and regulators of intracellular pH
- (2009) Joseph R. Casey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles
- (2009) Alex Yuan et al. PLoS One
- Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform
- (2008) Liangfang Zhang et al. ACS Nano
- Gold nanoparticles in delivery applications☆
- (2008) P GHOSH et al. ADVANCED DRUG DELIVERY REVIEWS
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- (2008) Yosuke Obata et al. BIOCONJUGATE CHEMISTRY
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- (2008) Satoru Sonoke et al. CANCER RESEARCH
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- (2008) Noritaka Odani et al. DEVELOPMENT GROWTH & DIFFERENTIATION
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- (2008) Juan M Irache et al. Expert Opinion on Drug Delivery
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- (2008) A. Manosroi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2008) H. Faneca et al. JOURNAL OF CONTROLLED RELEASE
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- (2008) Zhaohua Huang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2008) Aws Alshamsan et al. MOLECULAR PHARMACEUTICS
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- (2008) M. Frank-Kamenetsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2007) Shyh-Dar Li et al. JOURNAL OF CONTROLLED RELEASE
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- (2007) Benjamin Leader et al. NATURE REVIEWS DRUG DISCOVERY
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