Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles

Fluorescence microscopy colocalization of lipid–nucleic acid nanoparticles with wildtype and mutant Rab5–GFP: A platform for investigating early endosomal events

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Controlled Drug Delivery: Historical perspective for the next generation

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Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents

(2015) Igor V. Zhigaltsev et al.   JOURNAL OF LIPOSOME RESEARCH

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

(2015) Anders Wittrup et al.   NATURE BIOTECHNOLOGY

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

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Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles

(2013) Mark J. Ernsting et al.   JOURNAL OF CONTROLLED RELEASE

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(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

(2013) Barbara L Mui et al.   Molecular Therapy-Nucleic Acids

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The endocytosis and intracellular fate of nanomedicines: Implication for rational design

(2013) Longfa Kou et al.   Asian Journal of Pharmaceutical Sciences

Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery

(2012) Christian Dohmen et al.   ACS Nano

Cationic lipids activate intracellular signaling pathways

(2012) Caroline Lonez et al.   ADVANCED DRUG DELIVERY REVIEWS

Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid

(2012) Chia-Ling Chan et al.   BIOMATERIALS

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

(2012) Alex K. K. Leung et al.   Journal of Physical Chemistry C

Self-Assembly of Stable Monomolecular Nucleic Acid Lipid Particles with a Size of 30 nm

(2012) Sophia Rudorf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-Labile Traceless Click Linker for Protein Transduction

(2012) Kevin Maier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing

(2012) Igor V. Zhigaltsev et al.   LANGMUIR

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

(2012) Nathan M Belliveau et al.   Molecular Therapy-Nucleic Acids

Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid

(2011) Hiroto Hatakeyama et al.   BIOMATERIALS

Altering the immune response with lipid-based nanoparticles

(2011) Dalit Landesman-Milo et al.   JOURNAL OF CONTROLLED RELEASE

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

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Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

(2009) Ayman El-Sayed et al.   AAPS Journal

Preparation of nanoparticles by continuous-flow microfluidics

(2008) Andreas Jahn et al.   JOURNAL OF NANOPARTICLE RESEARCH

Microfluidic Platform for Controlled Synthesis of Polymeric Nanoparticles

(2008) Rohit Karnik et al.   NANO LETTERS

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Nanoparticles for drug delivery: The need for precision in reporting particle size parameters

(2007) Marie Gaumet et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS