Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy

(2019) Gulsah Erel-Akbaba et al.   ACS Nano

Extracellular vesicles: exosomes, microparticles, their parts, and their targets to enable their biomanufacturing and clinical applications

(2019) Chen-Yuan Kao et al.   CURRENT OPINION IN BIOTECHNOLOGY

A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4

(2018) Scott W. Messenger et al.   JOURNAL OF CELL BIOLOGY

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens

(2018) Mario Leonardo Squadrito et al.   NATURE METHODS

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

(2018) Ryosuke Kojima et al.   Nature Communications

Efficient RNA drug delivery using red blood cell extracellular vesicles

(2018) Waqas Muhammad Usman et al.   Nature Communications

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

(2018) Franz L. Ricklefs et al.   Science Advances

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

(2018) Joseph A. Fraietta et al.   NATURE

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue

(2017) Daniel Gallego-Perez et al.   Nature Nanotechnology

Exosomal Markers (CD63 and CD9) Expression Pattern Using Immunohistochemistry in Resected Malignant and Nonmalignant Pancreatic Specimens

(2017) Moh’d Khushman et al.   PANCREAS

Closed-loop control of targeted ultrasound drug delivery across the blood–brain/tumor barriers in a rat glioma model

(2017) Tao Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional Photonics Nanoparticles for Crossing the Blood-Brain Barrier and Effecting Optically Trackable Brain Theranostics

(2016) Ajay Singh et al.   ADVANCED FUNCTIONAL MATERIALS

Extracellular mRNA Detected by Tethered Lipoplex Nanoparticle Biochip for Lung Adenocarcinoma Detection

(2016) L. James Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protective effect of α-mangostin against iodixanol-induced apoptotic damage in LLC-PK1 cells

(2016) Dahae Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

(2016) Zhaogang Yang et al.   JOURNAL OF CONTROLLED RELEASE

Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers

(2016) Daniel Gallego-Perez et al.   Nanomedicine-Nanotechnology Biology and Medicine

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

(2016) Erica N. Borducchi et al.   NATURE

In vitro and ex vivo strategies for intracellular delivery

(2016) Martin P. Stewart et al.   NATURE

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Culture and Identification of Mouse Bone Marrow-Derived Dendritic Cells and Their Capability to Induce T Lymphocyte Proliferation

(2016) Wenguang Wang et al.   MEDICAL SCIENCE MONITOR

AD-Peptide Ligand of Nicotine Acetylcholine Receptors for Brain-Targeted Drug Delivery

(2015) Xiaoli Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma

(2013) Eun Ji Chung et al.   BIOMATERIALS

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

(2012) Ronne Wee Yeh Yeo et al.   ADVANCED DRUG DELIVERY REVIEWS

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Nanochannel electroporation delivers precise amounts of biomolecules into living cells

(2011) Pouyan E. Boukany et al.   Nature Nanotechnology

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

(2009) D Walerych et al.   ONCOGENE

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

(2008) A Lespagnol et al.   CELL DEATH AND DIFFERENTIATION