Ionizable Amphiphilic Dendrimer-Based Nanomaterials with Alkyl-Chain-Substituted Amines for Tunable siRNA Delivery to the Liver Endothelium In Vivo

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

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Small RNA combination therapy for lung cancer

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Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

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Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

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Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

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Can nanomedicines kill cancer stem cells?

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Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

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Copolymer of poly(ethylene glycol) and poly(l-lysine) grafting polyethylenimine through a reducible disulfide linkage for siRNA delivery

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Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

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Hyperbranched Polymeric “Star Vectors” for Effective DNA or siRNA Delivery

(2012) Yasuhide Nakayama   ACCOUNTS OF CHEMICAL RESEARCH

An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

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Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

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The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

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Glycine-Terminated Dendritic Amphiphiles for Nonviral Gene Delivery

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Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

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Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing

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Intrinsically Fluorescent PAMAM Dendrimer as Gene Carrier and Nanoprobe for Nucleic Acids Delivery: Bioimaging and Transfection Study

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Poly(propyleneimine) dendrimers as potential siRNA delivery nanocarrier: from structure to function

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Lipid-like materials for low-dose, in vivo gene silencing

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Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells

(2009) Dhananjay Jere et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery

(2009) Dong Wook Lee et al.   JOURNAL OF CONTROLLED RELEASE

In vivo siRNA delivery with dendritic poly(l-lysine) for the treatment of hypercholesterolemia

(2009) Kazuto Watanabe et al.   Molecular BioSystems

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

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Cooperative nanomaterial system to sensitize, target, and treat tumors

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Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

(2008) Arkadi Zintchenko et al.   BIOCONJUGATE CHEMISTRY

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Efficient delivery of siRNA using dendritic poly(l-lysine) for loss-of-function analysis

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