标题
Biomedical applications of mRNA nanomedicine
作者
关键词
messenger RNA, chemical modification, nanoparticle, vaccination, gene editing, protein-replacement, cellular reprogramming and engineering
出版物
Nano Research
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-07-27
DOI
10.1007/s12274-018-2146-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine
- (2018) Hyokyoung Kwon et al. BIOMATERIALS
- Dual-responsive polyplexes with enhanced disassembly and endosomal escape for efficient delivery of siRNA
- (2018) Jia Zhu et al. BIOMATERIALS
- Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer
- (2018) Lina Liu et al. MOLECULAR THERAPY
- mRNA Vaccine with Antigen-Specific Checkpoint Blockade Induces an Enhanced Immune Response against Established Melanoma
- (2018) Yuhua Wang et al. MOLECULAR THERAPY
- Targeted mRNA Therapy for Ornithine Transcarbamylase Deficiency
- (2018) Mary G. Prieve et al. MOLECULAR THERAPY
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Recent Progress in Delivery of Therapeutic and Imaging Agents Utilizing Organic-Inorganic Hybrid Nanoparticles
- (2018) Sheikh Tanzina Haque et al. Current Drug Delivery
- Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems
- (2017) S Guan et al. GENE THERAPY
- Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides
- (2017) Manuela Chiper et al. JOURNAL OF CONTROLLED RELEASE
- Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial
- (2017) Martin Alberer et al. LANCET
- Chitosan/Hyaluronic Acid Nanoparticles: Rational Design Revisited for RNA Delivery
- (2017) Enrique Lallana et al. MOLECULAR PHARMACEUTICS
- A Targeted and Stable Polymeric Nanoformulation Enhances Systemic Delivery of mRNA to Tumors
- (2017) Qixian Chen et al. MOLECULAR THERAPY
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA
- (2017) Siddharth Patel et al. NANO LETTERS
- Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy
- (2017) Xiaoding Xu et al. NANO LETTERS
- Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
- (2017) X. Luo et al. Nanoscale
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
- (2017) Hao Yin et al. NATURE BIOTECHNOLOGY
- Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
- (2017) Kathrin Leppek et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation
- (2017) Anna M. Rydzik et al. NUCLEIC ACIDS RESEARCH
- Systemic delivery of factor IX messenger RNA for protein replacement therapy
- (2017) Suvasini Ramaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics—An innate immune system standpoint
- (2017) Yasmin Granot et al. SEMINARS IN IMMUNOLOGY
- Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells
- (2017) Adam Nowakowski et al. Scientific Reports
- Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia
- (2017) Ding An et al. Cell Reports
- A new developing class of gene delivery: messenger RNA-based therapeutics
- (2017) Zhao Meng et al. Biomaterials Science
- Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA
- (2017) Eva Schrom et al. Molecular Therapy-Nucleic Acids
- Tools for translation: non-viral materials for therapeutic mRNA delivery
- (2017) Khalid A. Hajj et al. Nature Reviews Materials
- Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency
- (2017) Bin Li et al. Nature Biomedical Engineering
- Final analysis of a phase I/IIa study with CV9103, an intradermally administered prostate cancer immunotherapy based on self-adjuvanted mRNA.
- (2017) H. Kübler et al. JOURNAL OF CLINICAL ONCOLOGY
- An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model
- (2017) Jasdave S. Chahal et al. Scientific Reports
- Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
- (2016) Owen S. Fenton et al. ADVANCED MATERIALS
- Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
- (2016) Jason B. Miller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
- (2016) James C. Kaczmarek et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Effects of Chemically Modified Messenger RNA on Protein Expression
- (2016) Bin Li et al. BIOCONJUGATE CHEMISTRY
- Chemically modified RNA induces osteogenesis of stem cells and human tissue explants as well as accelerates bone healing in rats
- (2016) Elizabeth R. Balmayor et al. BIOMATERIALS
- Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
- (2016) Satoshi Uchida et al. BIOMATERIALS
- Designing and incorporating a real world data approach to international drug development and use: what the UK offers
- (2016) Andrew Bate et al. DRUG DISCOVERY TODAY
- Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
- (2016) F DeRosa et al. GENE THERAPY
- Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside
- (2016) Victor Kotelianski et al. International Journal of Nanomedicine
- Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration
- (2016) Zohreh Sadat Badieyan et al. JOURNAL OF CONTROLLED RELEASE
- Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways
- (2016) Man Li et al. JOURNAL OF CONTROLLED RELEASE
- Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells
- (2016) Hye Yeon Choi et al. JOURNAL OF CONTROLLED RELEASE
- Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery
- (2016) Lutz Nuhn et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines
- (2016) Thomas Démoulins et al. Nanomedicine-Nanotechnology Biology and Medicine
- Ultra-small lipid–polymer hybrid nanoparticles for tumor-penetrating drug delivery
- (2016) Diana Dehaini et al. Nanoscale
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Dual-responsive nanoparticles based on oxidized pullulan and a disulfide-containing poly(β-amino) ester for efficient delivery of genes and chemotherapeutic agents targeting hepatoma
- (2016) Hemei Wang et al. Polymer Chemistry
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translational control by 5'-untranslated regions of eukaryotic mRNAs
- (2016) A. G. Hinnebusch et al. SCIENCE
- An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs
- (2016) Margit Schnee et al. PLoS Neglected Tropical Diseases
- V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Synthetic Modified mRNA Drives Reprogramming of Human Pancreatic Duct-Derived Cells Into Insulin-Secreting Cells
- (2016) Elisa Corritore et al. Stem Cells Translational Medicine
- Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors
- (2016) Tomas Koblas et al. Molecular Therapy-Nucleic Acids
- pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences
- (2016) Alexandra E Grier et al. Molecular Therapy-Nucleic Acids
- Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles
- (2016) Elias J. Sayour et al. OncoImmunology
- Biodegradable Dendronized Polymers for Efficient mRNA Delivery
- (2016) Nathan J. Oldenhuis et al. ChemistrySelect
- Terminal PEGylated DNA–Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents
- (2015) Lei Song et al. ACS Applied Materials & Interfaces
- 5′ UTR m6A Promotes Cap-Independent Translation
- (2015) Kate D. Meyer et al. CELL
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- Modified mRNA as an alternative to plasmid DNA (pDNA) for transcript replacement and vaccination therapy
- (2015) Hyewon Youn et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection
- (2015) Xiquan Liang et al. JOURNAL OF BIOTECHNOLOGY
- Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles
- (2015) Miyuki Baba et al. JOURNAL OF CONTROLLED RELEASE
- N 1 -methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
- (2015) Oliwia Andries et al. JOURNAL OF CONTROLLED RELEASE
- Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
- (2015) Michela Brazzoli et al. JOURNAL OF VIROLOGY
- Hopx and the Cardiomyocyte Parentage
- (2015) Michael D Schneider et al. MOLECULAR THERAPY
- An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo
- (2015) Bin Li et al. NANO LETTERS
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization
- (2015) Binyamin D. Berkovits et al. NATURE
- Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery
- (2015) Liliana Wroblewska et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- Clinical experiences with systemically administered siRNA-based therapeutics in cancer
- (2015) Jonathan E. Zuckerman et al. NATURE REVIEWS DRUG DISCOVERY
- Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases
- (2015) Akitsugu Matsui et al. Scientific Reports
- Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study
- (2015) Hubert Kübler et al. Journal for ImmunoTherapy of Cancer
- Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity
- (2015) Satoshi Uchida et al. Pharmaceutics
- Multifunctional DNA-Gold Nanoparticles for Targeted Doxorubicin Delivery
- (2014) Colleen M. Alexander et al. BIOCONJUGATE CHEMISTRY
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos
- (2014) Yuyu Niu et al. CELL
- Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
- (2014) Delphine Goubau et al. NATURE
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- mRNA-based therapeutics — developing a new class of drugs
- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
- Engineering adeno-associated viruses for clinical gene therapy
- (2014) Melissa A. Kotterman et al. NATURE REVIEWS GENETICS
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes
- (2014) Joanna Kowalska et al. NUCLEIC ACIDS RESEARCH
- Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs
- (2014) Kamen P. Simeonov et al. PLoS One
- Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
- (2014) Thomas S. Ligon et al. PLoS One
- A well-defined coil–comb polycationic brush with “star polymers” as side chains for gene delivery
- (2014) Mingming Zhang et al. Polymer Chemistry
- mRNA-based vaccines synergize with radiation therapy to eradicate established tumors
- (2014) Mariola Fotin-Mleczek et al. Radiation Oncology
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- A critical analysis of codon optimization in human therapeutics
- (2014) Vincent P. Mauro et al. TRENDS IN MOLECULAR MEDICINE
- Effective gene targeting in rabbits using RNA-guided Cas9 nucleases
- (2014) Dongshan Yang et al. Journal of Molecular Cell Biology
- Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
- (2014) Kyle K. L. Phua et al. Scientific Reports
- Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo
- (2014) Kenneth C McCullough et al. Molecular Therapy-Nucleic Acids
- Chitosans for delivery of nucleic acids
- (2013) Michael D. Buschmann et al. ADVANCED DRUG DELIVERY REVIEWS
- Degradable Terpolymers with Alkyl Side Chains Demonstrate Enhanced Gene Delivery Potency and Nanoparticle Stability
- (2013) Ahmed A. Eltoukhy et al. ADVANCED MATERIALS
- mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation
- (2013) O. Levy et al. BLOOD
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
- (2013) Bin Shen et al. CELL RESEARCH
- Single-cell mRNA transfection studies: Delivery, kinetics and statistics by numbers
- (2013) Carolin Leonhardt et al. Nanomedicine-Nanotechnology Biology and Medicine
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
- (2013) Lior Zangi et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Reprogramming human fibroblasts to pluripotency using modified mRNA
- (2013) Pankaj K Mandal et al. Nature Protocols
- Inhibition of Xenograft Tumor Growth by Gold Nanoparticle-DNA Oligonucleotide Conjugates-Assisted Delivery of BAX mRNA
- (2013) Ji-Hyun Yeom et al. PLoS One
- The CRISPR Craze
- (2013) E. Pennisi SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Challenges and advances towards the rational design of mRNA vaccines
- (2013) Charlotte Pollard et al. TRENDS IN MOLECULAR MEDICINE
- Self-assembled inorganic/organic hybrid nanoparticles with multi-functionalized surfaces for active targeting drug delivery
- (2013) Ping Liang et al. Journal of Materials Chemistry B
- Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice
- (2013) Armin Hekele et al. Emerging Microbes & Infections
- Design of an Optimized Wilms’ Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo
- (2013) Daphné Benteyn et al. Molecular Therapy-Nucleic Acids
- mRNA Delivery through Fibronectin Associated Liposome-Apatite Particles: A New Approach for Enhanced mRNA Transfection to Mammalian Cell
- (2012) Fatema Tuj Zohra et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Multifunctional triblock copolymers for intracellular messenger RNA delivery
- (2012) Connie Cheng et al. BIOMATERIALS
- mRNA as a Versatile Tool for Exogenous Protein Expression
- (2012) Andreas N. Kuhn et al. CURRENT GENE THERAPY
- UU/UA Dinucleotide Frequency Reduction in Coding Regions Results in Increased mRNA Stability and Protein Expression
- (2012) Maher Al-Saif et al. MOLECULAR THERAPY
- Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy
- (2012) Yuhua Wang et al. MOLECULAR THERAPY
- Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
- (2012) Charlotte Pollard et al. MOLECULAR THERAPY
- Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
- (2012) Benjamin Petsch et al. NATURE BIOTECHNOLOGY
- Translational control by changes in poly(A) tail length: recycling mRNAs
- (2012) Laure Weill et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Nonviral delivery of self-amplifying RNA vaccines
- (2012) A. J. Geall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.
- (2012) Eva Matoulkova et al. RNA Biology
- Speeding with control: codon usage, tRNAs, and ribosomes
- (2012) Eva Maria Novoa et al. TRENDS IN GENETICS
- Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA
- (2012) Luigi Warren et al. Scientific Reports
- Differentially Charged Hollow Core/Shell Lipid-Polymer-Lipid Hybrid Nanoparticles for Small Interfering RNA Delivery
- (2011) Jinjun Shi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cellular IRES-mediated translation
- (2011) Anton A Komar et al. CELL CYCLE
- In Vitroandin VivomRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
- (2011) Xingfang Su et al. MOLECULAR PHARMACEUTICS
- Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
- (2011) Federico Perche et al. Nanomedicine-Nanotechnology Biology and Medicine
- Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
- (2011) Michael S D Kormann et al. NATURE BIOTECHNOLOGY
- Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L
- (2011) B. R. Anderson et al. NUCLEIC ACIDS RESEARCH
- PEGylation Improves Nanoparticle Formation and Transfection Efficiency of Messenger RNA
- (2011) Senta Üzgün et al. PHARMACEUTICAL RESEARCH
- Polymer vectors via controlled/living radical polymerization for gene delivery
- (2011) F.J. Xu et al. PROGRESS IN POLYMER SCIENCE
- Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH
- (2011) W. Su et al. RNA
- Enhancement of In Vitro Translation by Gold Nanoparticle−DNA Conjugates
- (2010) Sunho Park et al. ACS Nano
- Delivery of shRNA using gold nanoparticle–DNA oligonucleotide conjugates as a universal carrier
- (2010) Sang-Mi Ryou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors
- (2010) Eduard Yakubov et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
- (2010) A N Kuhn et al. GENE THERAPY
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
- Genome editing with engineered zinc finger nucleases
- (2010) Fyodor D. Urnov et al. NATURE REVIEWS GENETICS
- Synonymous but not the same: the causes and consequences of codon bias
- (2010) Joshua B. Plotkin et al. NATURE REVIEWS GENETICS
- Synthetic mRNA cap analogs with a modified triphosphate bridge – synthesis, applications and prospects
- (2010) Jacek Jemielity et al. NEW JOURNAL OF CHEMISTRY
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
- (2010) Bart R. Anderson et al. NUCLEIC ACIDS RESEARCH
- Regulation of mRNA decapping
- (2010) You Li et al. Wiley Interdisciplinary Reviews-RNA
- Control of poly(A) tail length
- (2010) Christian R. Eckmann et al. Wiley Interdisciplinary Reviews-RNA
- High performance mRNA transfection through carbonate apatite–cationic liposome conjugates
- (2009) Fatema T. Zohra et al. BIOMATERIALS
- Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients
- (2009) Benjamin Weide et al. JOURNAL OF IMMUNOTHERAPY
- Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5′,5′ bridge containing methylenebis(phosphonate) modification
- (2009) Anna Maria Rydzik et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Coding-Sequence Determinants of Gene Expression in Escherichia coli
- (2009) G. Kudla et al. SCIENCE
- Viral vectors: from virology to transgene expression
- (2008) D Bouard et al. BRITISH JOURNAL OF PHARMACOLOGY
- Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients
- (2008) Ashley J. Knights et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Current prospects for mRNA gene delivery
- (2008) Ayako Yamamoto et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Bax mRNA therapy using cationic liposomes for human malignant melanoma
- (2008) Kenya Okumura et al. JOURNAL OF GENE MEDICINE
- Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
- (2008) Katalin Karikó et al. MOLECULAR THERAPY
- Multifunctional deadenylase complexes diversify mRNA control
- (2008) Aaron C. Goldstrohm et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
- (2008) S. J. J. Brouns et al. SCIENCE
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