Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
出版年份 2015 全文链接
标题
Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model
作者
关键词
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出版物
PLoS One
Volume 10, Issue 7, Pages e0133154
出版商
Public Library of Science (PLoS)
发表日期
2015-07-21
DOI
10.1371/journal.pone.0133154
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- (2014) Masahiro Suzuki et al. PLoS One
- Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
- (2014) Kathryn A. Whitehead et al. Nature Communications
- Drug delivery strategies in the therapy of inflammatory bowel disease
- (2013) Christian Lautenschläger et al. ADVANCED DRUG DELIVERY REVIEWS
- Multifunctional polymeric nanoparticles for oral delivery of TNF-α siRNA to macrophages
- (2013) Chunbai He et al. BIOMATERIALS
- Overcoming therapeutic obstacles in inflammatory bowel diseases: A comprehensive review on novel drug delivery strategies
- (2013) F. Talaei et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: In vitro investigations
- (2013) Jianfeng Guo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease
- (2013) Ole Haagen Nielsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Unique insights into the intestinal absorption, transit, and subsequent biodistribution of polymer-derived microspheres
- (2013) Joshua J. Reineke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vitro–In Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery
- (2012) Kathryn A. Whitehead et al. ACS Nano
- Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome
- (2012) Michael Camilleri et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Synthesis, Characterization, and Evaluation of Ionizable Lysine-Based Lipids for siRNA Delivery
- (2012) Colin L. Walsh et al. BIOCONJUGATE CHEMISTRY
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- RNA-Based Therapeutics: Current Progress and Future Prospects
- (2012) John C. Burnett et al. CHEMISTRY & BIOLOGY
- Mechanisms of tumor necrosis factor-alpha-induced leaks in intestine epithelial barrier
- (2012) Fang He et al. CYTOKINE
- Nano- and microparticulate drug carriers for targeting of the inflamed intestinal mucosa
- (2012) Eva-Maria Collnot et al. JOURNAL OF CONTROLLED RELEASE
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
- Tight Junction Pore and Leak Pathways: A Dynamic Duo
- (2011) Le Shen et al. Annual Review of Physiology
- On the functional diversity of glyceraldehyde-3-phosphate dehydrogenase: Biochemical mechanisms and regulatory control
- (2011) Michael A. Sirover BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Use of biological molecules in the treatment of inflammatory bowel disease
- (2011) O. H. Nielsen et al. JOURNAL OF INTERNAL MEDICINE
- Intestinal homeostasis and its breakdown in inflammatory bowel disease
- (2011) Kevin J. Maloy et al. NATURE
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
- (2011) Daniel J. Siegwart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stimuli-Sensitive Synthetic Polypeptide-Based Materials for Drug and Gene Delivery
- (2011) Chaoliang He et al. Advanced Healthcare Materials
- Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery
- (2010) Kerry P. Mahon et al. BIOCONJUGATE CHEMISTRY
- Oral nuclear factor-κB decoy oligonucleotides delivery system with chitosan modified poly(d,l-lactide-co-glycolide) nanospheres for inflammatory bowel disease
- (2010) Kohei Tahara et al. BIOMATERIALS
- Oral TNF-α gene silencing using a polymeric microsphere-based delivery system for the treatment of inflammatory bowel disease
- (2010) Christina Kriegel et al. JOURNAL OF CONTROLLED RELEASE
- Endosomal escape pathways for delivery of biologicals
- (2010) Amir K. Varkouhi et al. JOURNAL OF CONTROLLED RELEASE
- Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines
- (2010) D. Scott Wilson et al. NATURE MATERIALS
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Permeability for Intestinal Absorption: Caco-2 Assay and Related Issues
- (2008) Barry Press et al. CURRENT DRUG METABOLISM
- Development of bioadhesive amino-pegylated poly(anhydride) nanoparticles designed for oral DNA delivery
- (2008) Krassimira Yoncheva et al. JOURNAL OF MICROENCAPSULATION
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
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