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Title
Interorgan Metabolic Crosstalk in Human Insulin Resistance
Authors
Keywords
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Journal
PHYSIOLOGICAL REVIEWS
Volume 98, Issue 3, Pages 1371-1415
Publisher
American Physiological Society
Online
2018-05-16
DOI
10.1152/physrev.00015.2017
References
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Note: Only part of the references are listed.- Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis
- (2018) Maria Apostolopoulou et al. DIABETES CARE
- Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study
- (2018) Paraskevi Detopoulou et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Impaired “Glycine”-mia in Type 2 Diabetes and Potential Mechanisms Contributing to Glucose Homeostasis
- (2017) Richard Yan-Do et al. ENDOCRINOLOGY
- Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes
- (2017) Mariya Markova et al. GASTROENTEROLOGY
- Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals
- (2017) Emanuel E. Canfora et al. GASTROENTEROLOGY
- Amino Acid and Fatty Acid Levels Affect Hepatic Phosphorus Metabolite Content in Metabolically Healthy Humans
- (2017) Sabine Kahl et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance
- (2017) Elisa Álvarez Hernández et al. JOURNAL OF CLINICAL INVESTIGATION
- A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans
- (2017) DAVID A. HOLDSWORTH et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
- (2017) Matthew D Lynes et al. NATURE MEDICINE
- High dietary choline and betaine intake is associated with low insulin resistance in the Newfoundland population
- (2017) Xiang Gao et al. NUTRITION
- Jejunal gluconeogenesis associated with insulin resistance level and its evolution after Roux-en-Y gastric bypass
- (2017) Carolina Gutierrez-Repiso et al. Surgery for Obesity and Related Diseases
- Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
- (2017) Max C. Petersen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
- (2017) Kasper W. ter Horst et al. Cell Reports
- Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans
- (2017) Leonore Wigger et al. Cell Reports
- Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians
- (2017) Anne Gemmink et al. Scientific Reports
- Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study
- (2017) Vanessa D. de Mello et al. Scientific Reports
- Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial
- (2017) Emanuel E. Canfora et al. Scientific Reports
- Alterations of Mitochondrial Function and Insulin Sensitivity in Human Obesity and Diabetes Mellitus
- (2016) Chrysi Koliaki et al. Annual Review of Nutrition
- Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
- (2016) Matthew J. Kolar et al. BIOCHEMISTRY
- Alpha-Ketoglutarate: Physiological Functions and Applications
- (2016) Nan Wu et al. Biomolecules & Therapeutics
- From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
- (2016) Ara Koh et al. CELL
- Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by 13 C Magnetic Resonance Spectroscopy
- (2016) Kitt Falk Petersen et al. Cell Metabolism
- Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism
- (2016) Bhagirath Chaurasia et al. Cell Metabolism
- Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men
- (2016) C. M. van der Beek et al. CLINICAL SCIENCE
- What Have Metabolomics Approaches Taught Us About Type 2 Diabetes?
- (2016) Alba Gonzalez-Franquesa et al. Current Diabetes Reports
- Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes
- (2016) Sofiya Gancheva et al. DIABETES
- GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects
- (2016) Pedro M. Moraes-Vieira et al. DIABETES
- α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance
- (2016) Jeff Cobb et al. DIABETES CARE
- Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses
- (2016) Jennifer Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biomarkers of Ectopic Fat Deposition: The Next Frontier in Serum Lipidomics
- (2016) Leigh Perreault et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes
- (2016) Birgit Knebel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance
- (2016) Max C. Petersen et al. JOURNAL OF CLINICAL INVESTIGATION
- The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
- (2016) Varman T. Samuel et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipose tissue in control of metabolism
- (2016) Liping Luo et al. JOURNAL OF ENDOCRINOLOGY
- EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
- (2016) JOURNAL OF HEPATOLOGY
- Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease
- (2016) Panu K. Luukkonen et al. JOURNAL OF HEPATOLOGY
- Adipose tissue regulates insulin sensitivity: role of adipogenesis,de novolipogenesis and novel lipids
- (2016) U. Smith et al. JOURNAL OF INTERNAL MEDICINE
- Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes
- (2016) Michael Taulo Lund et al. JOURNAL OF PHYSIOLOGY-LONDON
- Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study
- (2016) Eef Boets et al. JOURNAL OF PHYSIOLOGY-LONDON
- Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2
- (2016) Emily C. Graff et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Human gut microbes impact host serum metabolome and insulin sensitivity
- (2016) Helle Krogh Pedersen et al. NATURE
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- (2016) Rachel J. Perry et al. NATURE
- A LC-MS–based workflow for measurement of branched fatty acid esters of hydroxy fatty acids
- (2016) Tejia Zhang et al. Nature Protocols
- Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus
- (2016) Matthijs K. C. Hesselink et al. Nature Reviews Endocrinology
- NAFLD and diabetes mellitus
- (2016) Herbert Tilg et al. Nature Reviews Gastroenterology & Hepatology
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- (2016) Sara Tulipani et al. Obesity
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- (2016) Katherine T. Tonks et al. Obesity
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- (2016) Lindsey A. Muir et al. Obesity
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- (2016) Dagfinn Aune et al. BMJ-British Medical Journal
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- (2016) Dagfinn Aune et al. BMJ-British Medical Journal
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- (2015) Rachel J. Perry et al. CELL
- Acetyl Coenzyme A: A Central Metabolite and Second Messenger
- (2015) Federico Pietrocola et al. Cell Metabolism
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- (2015) Chrysi Koliaki et al. Cell Metabolism
- Evaluation of the Effect of Enteral Lipid Sensing on Endogenous Glucose Production in Humans
- (2015) Changting Xiao et al. DIABETES
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- (2015) Gijs den Besten et al. DIABETES
- Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans
- (2015) Erin L. Glynn et al. DIABETOLOGIA
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- (2015) Sylvie Caspar-Bauguil et al. DIABETOLOGIA
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- (2015) Therese Tillin et al. DIABETOLOGIA
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- (2015) Alwine F. M. Kardinaal et al. FASEB JOURNAL
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- (2015) Kenny L. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2015) Kristian H. Mikkelsen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Lipid-mediated muscle insulin resistance: different fat, different pathways?
- (2015) Olesja Ritter et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
- (2015) Courtney R Green et al. Nature Chemical Biology
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- (2015) Yun-Hee Youm et al. NATURE MEDICINE
- Short-chain fatty acids in control of body weight and insulin sensitivity
- (2015) Emanuel E. Canfora et al. Nature Reviews Endocrinology
- Ceramides – Lipotoxic Inducers of Metabolic Disorders
- (2015) Bhagirath Chaurasia et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals
- (2015) Kenji Uno et al. Nature Communications
- Characterization of hepatic lipid profiles in a mouse model with nonalcoholic steatohepatitis and subsequent fibrosis
- (2015) Kosuke Saito et al. Scientific Reports
- Effects of Acute Exposure to Increased Plasma Branched-Chain Amino Acid Concentrations on Insulin-Mediated Plasma Glucose Turnover in Healthy Young Subjects
- (2015) Sarah Everman et al. PLoS One
- The Intra- or Extracellular Redox State Was Not Affected by a High vs. Low Glycemic Response Diet in Mice
- (2015) Amber S. Kleckner et al. PLoS One
- Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease
- (2015) Sulin Cheng et al. PLoS One
- Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes
- (2015) Scott B. Crown et al. PLoS One
- Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance
- (2014) John J. Dubé et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Acylcarnitines activate proinflammatory signaling pathways
- (2014) Jennifer M. Rutkowsky et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Effects of betaine on performance and body composition: a review of recent findings and potential mechanisms
- (2014) Jason M. Cholewa et al. AMINO ACIDS
- Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease
- (2014) April D. Lake et al. AMINO ACIDS
- Metabolites in the choline oxidation pathway in relation to diabetes, glycemic control and insulin sensitivity among patients with angina pectoris
- (2014) G. Svingen et al. ATHEROSCLEROSIS
- Role of free fatty acid receptors in the regulation of energy metabolism
- (2014) Takafumi Hara et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
- (2014) Mark M. Yore et al. CELL
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- (2014) Filipe De Vadder et al. CELL
- Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
- (2014) Sarah M. Turpin et al. Cell Metabolism
- Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
- (2014) Ingrid Wernstedt Asterholm et al. Cell Metabolism
- Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation
- (2014) Francis B. Stephens et al. CLINICAL SCIENCE
- Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation
- (2014) Gordon I. Smith et al. DIABETES
- Novel Metabolic Markers for the Risk of Diabetes Development in American Indians
- (2014) Jinying Zhao et al. DIABETES CARE
- Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: a randomised feasibility trial
- (2014) Bettina Nowotny et al. DIABETOLOGIA
- Kinetic model of acetate metabolism in healthy and hyperinsulinaemic humans
- (2014) J Fernandes et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- High dietary protein intake, reducing or eliciting insulin resistance?
- (2014) A Rietman et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Sa1062 Effect of 12 Weeks of Oral Betaine on Homeostasic Model Assessment of Insulin Resistance (Homa-IR) in Non-Diabetic Subjects With Mildly Elevated Fasting Blood Sugar
- (2014) David Nolan et al. GASTROENTEROLOGY
- Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
- (2014) Edward S Chambers et al. GUT
- Mapping of the circulating metabolome reveals α-ketoglutarate as a predictor of morbid obesity-associated non-alcoholic fatty liver disease
- (2014) E Rodríguez-Gallego et al. INTERNATIONAL JOURNAL OF OBESITY
- High Insulin Combined With Essential Amino Acids Stimulates Skeletal Muscle Mitochondrial Protein Synthesis While Decreasing Insulin Sensitivity in Healthy Humans
- (2014) Matthew M. Robinson et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Modulation of Amino Acid Metabolic Signatures by Supplemented Isoenergetic Diets Differing in Protein and Cereal Fiber Content
- (2014) John G. Hattersley et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Long–echo time MR spectroscopy for skeletal muscle acetylcarnitine detection
- (2014) Lucas Lindeboom et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2014) M. Cruz et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
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- (2014) Monique van Nielen et al. JOURNAL OF NUTRITION
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- (2014) Flavia Badoud et al. JOURNAL OF PROTEOME RESEARCH
- Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013
- (2014) Marie Ng et al. LANCET
- Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis
- (2014) Kazutoshi Yamada et al. LIVER INTERNATIONAL
- Palmitoleic Acid (N-7) Attenuates the Immunometabolic Disturbances Caused by a High-Fat Diet Independently of PPARα
- (2014) Camila O. Souza et al. MEDIATORS OF INFLAMMATION
- Mitochondrial form and function
- (2014) Jonathan R. Friedman et al. NATURE
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- (2014) Da Young Oh et al. NATURE MEDICINE
- Branched-chain amino acids in metabolic signalling and insulin resistance
- (2014) Christopher J. Lynch et al. Nature Reviews Endocrinology
- Adipose tissue monomethyl branched-chain fatty acids and insulin sensitivity: Effects of obesity and weight loss
- (2014) Xiong Su et al. Obesity
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- (2014) Wei Perng et al. Obesity
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- (2014) A. A. Gibson et al. Obesity Reviews
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- (2014) Michael S. Lustgarten et al. PLoS One
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- (2014) F. Payne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Julia Szendroedi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) H Hanamatsu et al. Nutrition & Diabetes
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- (2014) Nicola Aberdein et al. Adipocyte
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- (2014) Susan Duckett et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
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- (2013) Denise E. Lackey et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2013) Gijs den Besten et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
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- (2013) Weiwei Wang et al. AMINO ACIDS
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- (2013) Jonathan Y. Xia et al. BIOCHIMIE
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- (2013) Leanne Hodson et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
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- (2013) L. E. H. Bakker et al. DIABETES
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- (2013) W. Xie et al. DIABETES
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- (2013) C. Menni et al. DIABETES
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- (2013) Xinwei Li et al. PLoS One
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- (2013) Peter J. Meikle et al. PLoS One
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- (2013) Elke Binder et al. PLoS One
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- (2013) Leah Eissing et al. Nature Communications
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- (2012) K. E. Pinnick et al. DIABETES
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- (2012) Sara G Vienberg et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
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- (2012) Shireesh Srivastava et al. FASEB JOURNAL
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- (2012) Faidon Magkos et al. GASTROENTEROLOGY
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- (2012) Lindsay M. Edwards et al. JOURNAL OF LIPID RESEARCH
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- (2012) SoJung Lee et al. METABOLISM-CLINICAL AND EXPERIMENTAL
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- (2012) Rui Wang-Sattler et al. Molecular Systems Biology
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- (2012) Atsuhiko Ichimura et al. NATURE
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- (2012) Harry J. Flint et al. Nature Reviews Gastroenterology & Hepatology
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- (2012) Xin Guo et al. PLoS One
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- (2011) Martin O Weickert et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction
- (2011) Jeffrey D Browning et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats
- (2011) Sunmin Park et al. BRAIN RESEARCH
- Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease
- (2011) Nishanth E. Sunny et al. Cell Metabolism
- Amino Acid-Dependent Activation of Liver Estrogen Receptor Alpha Integrates Metabolic and Reproductive Functions via IGF-1
- (2011) Sara Della Torre et al. Cell Metabolism
- Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates
- (2011) Ee L. Lim et al. CLINICAL SCIENCE
- Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways
- (2011) Fei Xiao et al. DIABETES
- Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?
- (2011) F. Amati et al. DIABETES
- Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes
- (2011) A. I. Schmid et al. DIABETES CARE
- Hyperaminoacidaemia at postprandial levels does not modulate glucose metabolism in type 2 diabetes mellitus
- (2011) M. Bassil et al. DIABETOLOGIA
- Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?
- (2011) A. Othman et al. DIABETOLOGIA
- Propionic acid affects immune status and metabolism in adipose tissue from overweight subjects
- (2011) Sa’ad Al-Lahham et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C
- (2011) Masao Honda et al. GASTROENTEROLOGY
- Dietary Methionine Restriction Increases Fat Oxidation in Obese Adults with Metabolic Syndrome
- (2011) Eric P. Plaisance et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Three Weeks on a High-Fat Diet Increases Intrahepatic Lipid Accumulation and Decreases Metabolic Flexibility in Healthy Overweight Men
- (2011) Noud A. van Herpen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Long- and Medium-Chain Fatty Acids Induce Insulin Resistance to a Similar Extent in Humans Despite Marked Differences in Muscle Fat Accumulation
- (2011) Joris Hoeks et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
- (2011) Eugene P. Rhee et al. JOURNAL OF CLINICAL INVESTIGATION
- Insulin sensitivity is not associated with palmitoleate availability in obese humans
- (2011) Elisa Fabbrini et al. JOURNAL OF LIPID RESEARCH
- Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men
- (2011) Myrte Brands et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- The role of mitochondria in insulin resistance and type 2 diabetes mellitus
- (2011) Julia Szendroedi et al. Nature Reviews Endocrinology
- Is Intestinal Gluconeogenesis a Key Factor in the Early Changes in Glucose Homeostasis Following Gastric Bypass?
- (2011) Mark Thomas Hayes et al. OBESITY SURGERY
- Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
- (2011) N. Kumashiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adipose tissue palmitoleic acid and obesity in humans: does it behave as a lipokine?
- (2010) Jian Gong et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Acute elevation of plasma lipids does not affect ATP synthesis in human skeletal muscle
- (2010) A. Brehm et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- β-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle
- (2010) Takashi Yamada et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
- (2010) François R. Jornayvaz et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine
- (2010) Elango Kathirvel et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease
- (2010) Zhigang Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
- (2010) Sa'ad H. Al-Lahham et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
- (2010) Da Young Oh et al. CELL
- Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle
- (2010) N. Lefort et al. DIABETES
- Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling
- (2010) L. D. Hoeg et al. DIABETES
- Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine
- (2010) R. V. Sekhar et al. DIABETES CARE
- Adipose tissue fatty acids and insulin sensitivity in elderly men
- (2010) D. Iggman et al. DIABETOLOGIA
- Regulation of adipokine production in human adipose tissue by propionic acid
- (2010) Sa’ad H. Al-Lahham et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men
- (2010) Lindsay M. Edwards et al. FASEB JOURNAL
- Activation ofN-Methyl-d-aspartate (NMDA) Receptors in the Dorsal Vagal Complex Lowers Glucose Production
- (2010) Carol K. L. Lam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Oxocarboxylic Acids
- (2010) Robert C. Kerber et al. JOURNAL OF CHEMICAL EDUCATION
- A High-Fat Diet Elicits Differential Responses in Genes Coordinating Oxidative Metabolism in Skeletal Muscle of Lean and Obese Individuals
- (2010) K. E. Boyle et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Lipid-induced insulin resistance: unravelling the mechanism
- (2010) Varman T Samuel et al. LANCET
- Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
- (2010) Stephanie J. Mihalik et al. Obesity
- α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population
- (2010) Walter E. Gall et al. PLoS One
- Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting
- (2010) Karsten Suhre et al. PLoS One
- Inhibiting gluconeogenesis prevents fatty acid-induced increases in endogenous glucose production
- (2009) Sylvia Kehlenbrink et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mitochondrial dysfunction and lipotoxicity
- (2009) Patrick Schrauwen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Expression of short-chain fatty acid receptor GPR41 in the human colon
- (2009) Hideaki Tazoe et al. BIOMEDICAL RESEARCH-TOKYO
- Glycine regulates inflammatory markers modifying the energetic balance through PPAR and UCP-2
- (2009) J.C. Almanza-Perez et al. BIOMEDICINE & PHARMACOTHERAPY
- Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-α
- (2009) Kristin R. Freeland et al. BRITISH JOURNAL OF NUTRITION
- GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
- (2009) M. Thangaraju et al. CANCER RESEARCH
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue
- (2009) Y. Cheng et al. DIABETES
- Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
- (2009) Z. Gao et al. DIABETES
- Circulating Palmitoleate Strongly and Independently Predicts Insulin Sensitivity in Humans
- (2009) N. Stefan et al. DIABETES CARE
- Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women
- (2009) K. M. Huffman et al. DIABETES CARE
- Dietary Fiber Supplements: Effects in Obesity and Metabolic Syndrome and Relationship to Gastrointestinal Functions
- (2009) Athanasios Papathanasopoulos et al. GASTROENTEROLOGY
- Betaine for nonalcoholic fatty liver disease: Results of a randomized placebo-controlled trial
- (2009) Manal F. Abdelmalek et al. HEPATOLOGY
- Abnormal hepatic energy homeostasis in type 2 diabetes
- (2009) Julia Szendroedi et al. HEPATOLOGY
- Changes in Basal and Insulin and Amino Acid Response of Whole Body and Skeletal Muscle Proteins in Obese Men
- (2009) Christelle Guillet et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Effect of Branched Chain Amino Acids on Skeletal Muscle Mitochondrial Function in Young and Elderly Adults
- (2009) Laura L. Tatpati et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
- (2009) Alberto O. Chavez et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women
- (2009) Sean H. Adams et al. JOURNAL OF NUTRITION
- Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men
- (2009) Charlotte Brøns et al. JOURNAL OF PHYSIOLOGY-LONDON
- Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome
- (2009) Guo-Xin Hu et al. MEDICAL HYPOTHESES
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Microbiota and SCFA in Lean and Overweight Healthy Subjects
- (2009) Andreas Schwiertz et al. Obesity
- GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
- (2009) Kashan Ahmed et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal men
- (2008) Olasunkanmi A. J. Adegoke et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism
- (2008) Haiming Cao et al. CELL
- Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
- (2008) Timothy R. Koves et al. Cell Metabolism
- Muscle acylcarnitines during short-term fasting in lean healthy men
- (2008) Maarten R. Soeters et al. CLINICAL SCIENCE
- Ectopic lipids and organ function
- (2008) Julia Szendroedi et al. CURRENT OPINION IN LIPIDOLOGY
- Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
- (2008) J. M. Haus et al. DIABETES
- Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice
- (2008) F.J. Alarcon-Aguilar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effects of dietary fibers on disturbances clustered in the metabolic syndrome
- (2007) Milagros Galisteo et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
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