Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans

Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity

(2015) S. Rodriguez-Cuenca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Improved insulin sensitivity after exercise training is linked to reduced plasma C14:0 ceramide in obesity and type 2 diabetes

(2015) Takhar Kasumov et al.   Obesity

Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression ofdegs1Impairs Adipocyte Differentiation and Function

(2014) Nuria Barbarroja et al.   DIABETES

Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans

(2014) F. Rosqvist et al.   DIABETES

Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults

(2014) H Hanamatsu et al.   Nutrition & Diabetes

A Single Session of Low-Intensity Exercise Is Sufficient to Enhance Insulin Sensitivity Into the Next Day in Obese Adults

(2013) Sean A. Newsom et al.   DIABETES CARE

Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics

(2013) Fengguo Xu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin andPCSK9Deficiency

(2013) Kirill Tarasov et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sphingomyelin Patches on Pancreatic Beta-cells Are Indicative of Insulin Secretory Capacity

(2013) Amol Kavishwar et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Ablation of Dihydroceramide Desaturase 1, a Therapeutic Target for the Treatment of Metabolic Diseases, Simultaneously Stimulates Anabolic and Catabolic Signaling

(2013) M. M. Siddique et al.   MOLECULAR AND CELLULAR BIOLOGY

The effect of short-term overfeeding on serum lipids in healthy humans

(2013) Leonie K. Heilbronn et al.   Obesity

Plasma dihydroceramide species associate with waist circumference in Mexican American families

(2013) Manju Mamtani et al.   Obesity

Plasma Lipid Profiling Shows Similar Associations with Prediabetes and Type 2 Diabetes

(2013) Peter J. Meikle et al.   PLoS One

Impact of Sphingomyelin Synthase 1 Deficiency on Sphingolipid Metabolism and Atherosclerosis in Mice

(2012) Zhiqiang Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance

(2012) J. Boon et al.   DIABETES

A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults

(2012) C. L. Kien et al.   DIABETES

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans

(2012) B. C. Bergman et al.   DIABETOLOGIA

Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet

(2012) J T Brozinick et al.   INTERNATIONAL JOURNAL OF OBESITY

High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance

(2012) Kayo Kurotani et al.   NUTRITION RESEARCH

Exercise increases plasma levels of sphingoid base-1 phosphates in humans

(2011) M. Baranowski et al.   Acta Physiologica

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels

(2011) Kittichai Promrat et al.   HEPATOLOGY RESEARCH

Gastric Bypass Surgery Reduces Plasma Ceramide Subspecies and Improves Insulin Sensitivity in Severely Obese Patients

(2011) Hazel Huang et al.   Obesity

C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements

(2010) Smadar Levy et al.   IUBMB LIFE

Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes

(2010) Bryan C. Bergman et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice

(2010) Masato Yano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood sphingolipidomics in healthy humans: impact of sample collection methodology

(2010) Samar M. Hammad et al.   JOURNAL OF LIPID RESEARCH

Fatty Fish Intake Decreases Lipids Related to Inflammation and Insulin Signaling—A Lipidomics Approach

(2009) Maria Lankinen et al.   PLoS One

Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

(2008) J. M. Haus et al.   DIABETES