Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
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Title
Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
Authors
Keywords
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Journal
MOLECULES
Volume 23, Issue 2, Pages 509
Publisher
MDPI AG
Online
2018-02-27
DOI
10.3390/molecules23020509
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Note: Only part of the references are listed.- Circadian Rhythms Disturbances in Alzheimer Disease
- (2018) Ángela Milán-Tomás et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress
- (2018) Ehsan Dehdashtian et al. LIFE SCIENCES
- The influence of vitamins E and C and exercise on brain aging
- (2017) J. Thomas Mock et al. EXPERIMENTAL GERONTOLOGY
- The role of mitochondrial ROS in the aging brain
- (2017) Rhoda Stefanatos et al. FEBS LETTERS
- Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen
- (2017) Shou-Long Deng et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cell Biology of the Mitochondrion
- (2017) Alexander M. van der Bliek et al. GENETICS
- Melatonin reduces inflammatory response in peripheral T helper lymphocytes from relapsing-remitting multiple sclerosis patients
- (2017) Nuria Álvarez-Sánchez et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC-1β: In vivo and in vitro studies
- (2017) Mengen Zhai et al. JOURNAL OF PINEAL RESEARCH
- Long-term melatonin treatment delays ovarian aging
- (2017) Hiroshi Tamura et al. JOURNAL OF PINEAL RESEARCH
- Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy
- (2017) Aparna Areti et al. JOURNAL OF PINEAL RESEARCH
- Dynamin-related protein 1-mediated mitochondrial fission contributes to post-traumatic cardiac dysfunction in rats and the protective effect of melatonin
- (2017) Mingge Ding et al. JOURNAL OF PINEAL RESEARCH
- Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential
- (2017) Xiaokui Huo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin systemically ameliorates drought stress-induced damage inMedicago sativaplants by modulating nitro-oxidative homeostasis and proline metabolism
- (2017) Chrystalla Antoniou et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: Antioxidant and modulatory properties in age-related changes during Trypanosoma cruzi infection
- (2017) Vânia Brazão et al. JOURNAL OF PINEAL RESEARCH
- HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants
- (2017) Shu-Yu Cai et al. JOURNAL OF PINEAL RESEARCH
- Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome
- (2017) Zhengwang Cao et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice
- (2017) Nabanita Das et al. JOURNAL OF PINEAL RESEARCH
- Melatonin enhances survival and preserves functional integrity of stem cells: A review
- (2017) Mel S. Lee et al. JOURNAL OF PINEAL RESEARCH
- RAV transcription factors are essential for disease resistance against cassava bacterial blight via activation of melatonin biosynthesis genes
- (2017) Yunxie Wei et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways
- (2017) Maryam Majidinia et al. JOURNAL OF PINEAL RESEARCH
- Chloroplast overexpression of rice caffeic acid O -methyltransferase increases melatonin production in chloroplasts via the 5-methoxytryptamine pathway in transgenic rice plants
- (2017) Geun-Hee Choi et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2-dependent pathway
- (2017) Longsen Han et al. JOURNAL OF PINEAL RESEARCH
- Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress
- (2017) Lin Wang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and sirtuins: A “not-so unexpected” relationship
- (2017) Juan C. Mayo et al. JOURNAL OF PINEAL RESEARCH
- Effects of melatonin on fatty liver disease: The role of NR4A1/DNA-PKcs/p53 pathway, mitochondrial fission, and mitophagy
- (2017) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Mechanism of melatonin protection against copper-ascorbate-induced oxidative damage in vitro through isothermal titration calorimetry
- (2017) Arnab K. Ghosh et al. LIFE SCIENCES
- Oxidative stress and frailty: A systematic review and synthesis of the best evidence
- (2017) Pinar Soysal et al. MATURITAS
- Telomere shortening during aging: Attenuation by antioxidants and anti-inflammatory agents
- (2017) Kedar N. Prasad et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Cadmium Disrupts Subcellular Organelles, Including Chloroplasts, Resulting in Melatonin Induction in Plants
- (2017) Hyoung-Yool Lee et al. MOLECULES
- Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases
- (2017) Ana López et al. PLoS One
- Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
- (2017) Yalikun Suofu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dietary Sources and Bioactivities of Melatonin
- (2017) Xiao Meng et al. Nutrients
- Endophytic Bacterium Pseudomonas fluorescens RG11 May Transform Tryptophan to Melatonin and Promote Endogenous Melatonin Levels in the Roots of Four Grape Cultivars
- (2017) Yaner Ma et al. Frontiers in Plant Science
- Cell Biology of the Mitochondrion
- (2017) Alexander M. van der Bliek et al. GENETICS
- The decay of Redox-stress Response Capacity is a substantive characteristic of aging: Revising the redox theory of aging
- (2017) Jiao Meng et al. Redox Biology
- Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress
- (2017) Helmut Sies Redox Biology
- Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress
- (2017) Xiaodong Zheng et al. Scientific Reports
- Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways
- (2017) Zorica Janjetovic et al. Scientific Reports
- Oxidative Modifications in Tissue Pathology and Autoimmune Disease
- (2017) Mei-Ling Yang et al. ANTIOXIDANTS & REDOX SIGNALING
- Melatonin production in Escherichia coli by dual expression of serotonin N-acetyltransferase and caffeic acid O-methyltransferase
- (2016) Yeong Byeon et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Redox regulation and pro-oxidant reactions in the physiology of circadian systems
- (2016) Isabel Méndez et al. BIOCHIMIE
- Targeting Mitochondria in Cardiovascular Diseases
- (2016) Filomena Silva et al. CURRENT PHARMACEUTICAL DESIGN
- Chronobiology of Aging: A Mini-Review
- (2016) Germaine Cornelissen et al. GERONTOLOGY
- Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics
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- (2016) Shangcheng Xu et al. JOURNAL OF PINEAL RESEARCH
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- (2016) Meng-Qi Li et al. JOURNAL OF PINEAL RESEARCH
- Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts
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- (2016) Yunxie Wei et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates postharvest physiological deterioration of cassava storage roots
- (2016) Qiuxiang Ma et al. JOURNAL OF PINEAL RESEARCH
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- (2016) Shih-Chi Su et al. JOURNAL OF PINEAL RESEARCH
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- (2016) Liming Yu et al. JOURNAL OF PINEAL RESEARCH
- Melatonin prevents the dynamin-related protein 1-dependent mitochondrial fission and oxidative insult in the cortical neurons after 1-methyl-4-phenylpyridinium treatment
- (2016) Jih-Ing Chuang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as an antioxidant: under promises but over delivers
- (2016) Russel J. Reiter et al. JOURNAL OF PINEAL RESEARCH
- Melatonin is required for H2O2- and NO-mediated defense signaling through MAPKKK3 and OXI1 inArabidopsis thaliana
- (2016) Hyoung Yool Lee et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates postmyocardial infarction injury via increasing Tom70 expression
- (2016) Hai-Feng Pei et al. JOURNAL OF PINEAL RESEARCH
- Melatonin, bone regulation and the ubiquitin-proteasome connection: A review
- (2016) Jerry Vriend et al. LIFE SCIENCES
- Melatonin’s role in preventing toxin-related and sepsis-mediated hepatic damage: A review
- (2016) Eduardo Esteban-Zubero et al. PHARMACOLOGICAL RESEARCH
- Effects of melatonin and metformin co-administration on testicular ischemia/reperfusion injury in rats
- (2016) Ahmad Asghari et al. Journal of Pediatric Urology
- The Circadian Nature of Mitochondrial Biology
- (2016) Gal Manella et al. Frontiers in Endocrinology
- Protective role of melatonin in mitochondrial dysfunction and related disorders
- (2015) Giuseppe Paradies et al. ARCHIVES OF TOXICOLOGY
- SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin
- (2015) Huifeng Pi et al. Autophagy
- Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review
- (2015) M. Ramis et al. CURRENT MEDICINAL CHEMISTRY
- ROS-dependent signal transduction
- (2015) Colleen R Reczek et al. CURRENT OPINION IN CELL BIOLOGY
- Melatonin Redox Activity. Its Potential Clinical Applications in Neurodegenerative Disorders
- (2015) Elzbieta Miller et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Quinone reductase 2 as a promising target of melatonin therapeutic actions
- (2015) Jean A Boutin EXPERT OPINION ON THERAPEUTIC TARGETS
- N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin
- (2015) Ruslán Álvarez-Diduk et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
- (2015) Amit Naskar et al. JOURNAL OF PINEAL RESEARCH
- Melatonin treatment improves primary progressive multiple sclerosis: a case report
- (2015) Antonio López-González et al. JOURNAL OF PINEAL RESEARCH
- Chloroplastic and cytoplasmic overexpression of sheep serotoninN-acetyltransferase in transgenic rice plants is associated with low melatonin production despite high enzyme activity
- (2015) Yeong Byeon et al. JOURNAL OF PINEAL RESEARCH
- Melatonin delays leaf senescence and enhances salt stress tolerance in rice
- (2015) Chengzhen Liang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer
- (2015) David Hevia et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable
- (2015) Lucien C. Manchester et al. JOURNAL OF PINEAL RESEARCH
- Functions of melatonin in plants: a review
- (2015) Marino B. Arnao et al. JOURNAL OF PINEAL RESEARCH
- Phytomelatonin: Assisting Plants to Survive and Thrive
- (2015) Russel Reiter et al. MOLECULES
- Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces
- (2014) Russel J. Reiter et al. Brain Structure & Function
- Cyclic-3-hydroxymelatonin (C3HOM), A Potent Antioxidant, Scavenges Free Radicals and Suppresses Oxidative Reactions
- (2014) Dun-Xian Tan et al. CURRENT MEDICINAL CHEMISTRY
- Endosymbiotic theory for organelle origins
- (2014) Verena Zimorski et al. CURRENT OPINION IN MICROBIOLOGY
- Melatonin regulates proteomic changes during leaf senescence inMalus hupehensis
- (2014) Ping Wang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats
- (2014) Aroa Jimenéz-Aranda et al. JOURNAL OF PINEAL RESEARCH
- Melatonin feedback on clock genes: a theory involving the proteasome
- (2014) Jerry Vriend et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis
- (2014) Annia Galano et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: Exceeding Expectations
- (2014) Russel J. Reiter et al. PHYSIOLOGY
- Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis
- (2013) D.A. Lowes et al. BRITISH JOURNAL OF ANAESTHESIA
- The role of mitochondria in aging
- (2013) Ana Bratic et al. JOURNAL OF CLINICAL INVESTIGATION
- Melatonin and female reproduction
- (2013) Hiroshi Tamura et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- Changes in the mitochondrial permeability transition pore in aging and age-associated diseases
- (2013) Giuseppe Paradies et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Antioxidant supplements in exercise: worse than useless?
- (2012) Mari Carmen Gomez-Cabrera et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
- (2012) Paul D. Ray et al. CELLULAR SIGNALLING
- Melatonin-mitochondria Interplay in Health and Disease
- (2012) Dario Acuna Castroviejo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
- (2012) Kalavathi Dasuri et al. FREE RADICAL BIOLOGY AND MEDICINE
- Diabetes, Metformin, and Breast Cancer: Lilac Time?
- (2012) Pamela J. Goodwin et al. JOURNAL OF CLINICAL ONCOLOGY
- Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes
- (2012) Dun-Xian Tan et al. JOURNAL OF PINEAL RESEARCH
- On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK
- (2012) Annia Galano et al. JOURNAL OF PINEAL RESEARCH
- Physiological Roles of Mitochondrial Reactive Oxygen Species
- (2012) Laura A. Sena et al. MOLECULAR CELL
- Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science
- (2011) D.-X. Tan et al. JOURNAL OF EXPERIMENTAL BOTANY
- The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity
- (2011) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice
- (2011) Carmen Vida et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signaling
- (2011) Natasa Dragicevic et al. JOURNAL OF PINEAL RESEARCH
- mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca2+, and lipid insults in NARP cybrids: a potential therapeutic target for melatonin
- (2011) Tsung-I Peng et al. JOURNAL OF PINEAL RESEARCH
- A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases
- (2011) Jörg H. Stehle et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as a natural ally against oxidative stress: a physicochemical examination
- (2011) Annia Galano et al. JOURNAL OF PINEAL RESEARCH
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- (2011) Carmen Venegas et al. JOURNAL OF PINEAL RESEARCH
- Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin
- (2011) Sergio A. Rosales-Corral et al. JOURNAL OF PINEAL RESEARCH
- Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
- (2011) Grant R. Drummond et al. NATURE REVIEWS DRUG DISCOVERY
- On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals
- (2011) Annia Galano PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- The sites and topology of mitochondrial superoxide production
- (2010) Martin D. Brand EXPERIMENTAL GERONTOLOGY
- Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease
- (2010) Giuseppe Paradies et al. JOURNAL OF PINEAL RESEARCH
- Melatonin in Plants
- (2010) Russel J. Reiter et al. NUTRITION REVIEWS
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- (2010) M. L. Dubocovich et al. PHARMACOLOGICAL REVIEWS
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- (2010) Vladimir I. Titorenko et al. TRAFFIC
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