Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells

(2015) Alejandro Romero et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects against behavioural dysfunctions and dendritic spine damage in 3-nitropropionic acid-induced rat model of Huntington's disease

(2014) J. Chakraborty et al.   BEHAVIOURAL BRAIN RESEARCH

Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa

(2014) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Tozadenant (SYN115) in patients with Parkinson's disease who have motor fluctuations on levodopa: a phase 2b, double-blind, randomised trial

(2014) Robert A Hauser et al.   LANCET NEUROLOGY

Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias

(2014) Olivier Rascol et al.   PARKINSONISM & RELATED DISORDERS

Neuroprotective effect of silymarin in a MPTP mouse model of Parkinson's disease

(2014) Jesús Pérez-H et al.   TOXICOLOGY

In vivoNMR studies of regional cerebral energetics in MPTP model of Parkinson's disease: recovery of cerebral metabolism with acute levodopa treatment

(2013) Puneet Bagga et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism

(2013) Amit Naskar et al.   JOURNAL OF PINEAL RESEARCH

Increased melatonin may play dual roles in the striata of a 6-hydroxydopamine model of Parkinson's disease

(2013) Ling Lin et al.   LIFE SCIENCES

Evidence-based guideline: Treatment of tardive syndromes: Report of the Guideline Development Subcommittee of the American Academy of Neurology

(2013) R. Bhidayasiri et al.   NEUROLOGY

Engraftment of Mouse Embryonic Stem Cells Differentiated by Default Leads to Neuroprotection, Behaviour Revival and Astrogliosis in Parkinsonian Rats

(2013) Debasmita Tripathy et al.   PLoS One

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

(2012) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

L-DOPA induced-endogenous 6-hydroxydopamine is the cause of aggravated dopaminergic neurodegeneration in Parkinson’s disease patients

(2012) Anupom Borah et al.   MEDICAL HYPOTHESES

Photobiomodulation enhances nigral dopaminergic cell survival in a chronic MPTP mouse model of Parkinson’s disease

(2012) Cassandra Peoples et al.   PARKINSONISM & RELATED DISORDERS

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration

(2011) Siau Bai et al.   BMC BIOLOGY

Mitochondrial DNA and inflammatory diseases

(2011) Germaine Escames et al.   HUMAN GENETICS

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease

(2011) Jennifer M. King et al.   LIFE SCIENCES

The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease

(2011) Klaus Seppi et al.   MOVEMENT DISORDERS

Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease

(2011) Gaurav Patki et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Resistance of Golden Hamster to l-Methyl-4-Phenyl-1,2,3,6 Tetrahydropyridine: Relationship with Low Levels of Regional Monoamine Oxidase B

(2010) N. Mitra et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents

(2009) Anupom Borah et al.   JOURNAL OF PINEAL RESEARCH

l-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation

(2009) Anupom Borah et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of Adenosine A2A Receptor Antagonists on l-DOPA-Induced Hydroxyl Radical Formation in Rat Striatum

(2009) Krystyna Gołembiowska et al.   NEUROTOXICITY RESEARCH

Placebo-controlled chronic high-frequency stimulation of the subthalamic nucleus preserves dopaminergic nigral neurons in a rat model of progressive Parkinsonism

(2007) Daniel Harnack et al.   EXPERIMENTAL NEUROLOGY