Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy

Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy

(2017) Prashanth Komirishetty et al.   NEUROPHARMACOLOGY

Potential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies

(2016) Aparna Areti et al.   Current Neuropharmacology

Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride-induced liver fibrosis

(2016) Jung-Woo Kang et al.   JOURNAL OF PINEAL RESEARCH

PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy

(2016) Prashanth Komirishetty et al.   LIFE SCIENCES

Morin Mitigates Chronic Constriction Injury (CCI)-Induced Peripheral Neuropathy by Inhibiting Oxidative Stress Induced PARP Over-Activation and Neuroinflammation

(2016) Prashanth Komirishetty et al.   NEUROCHEMICAL RESEARCH

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

(2016) J. Julie Wu et al.   Aging-US

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

(2015) Anna Fernández et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Protective effects of phosphatidylcholine on oxaliplatin-induced neuropathy in rats

(2015) Sung Tae Kim et al.   LIFE SCIENCES

Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms?

(2015) V.A. Carozzi et al.   NEUROSCIENCE LETTERS

Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression

(2014) Qinghua Dong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Boswellia ovalifoliolata abrogates ROS mediated NF-κB activation, causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells

(2014) Dinesh Thummuri et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Glial role in oxaliplatin-induced neuropathic pain

(2014) Lorenzo Di Cesare Mannelli et al.   EXPERIMENTAL NEUROLOGY

Proliferative effects of melatonin on Schwann cells: implication for nerve regeneration following peripheral nerve injury

(2014) Hung-Ming Chang et al.   JOURNAL OF PINEAL RESEARCH

Mitotoxicity in distal symmetrical sensory peripheral neuropathies

(2014) Gary J. Bennett et al.   Nature Reviews Neurology

The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model

(2014) Qi-Liang Mao-Ying et al.   PLoS One

Oxidative stress and nerve damage: Role in chemotherapy induced peripheral neuropathy

(2014) Aparna Areti et al.   Redox Biology

Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): A systematic review

(2013) Janet M. Schloss et al.   CLINICAL NUTRITION

Oxaliplatin-induced oxidative stress in nervous system-derived cellular models: Could it correlate with in vivo neuropathy?

(2013) L. Di Cesare Mannelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress and Neurodegenerative Disorders

(2013) Jie Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase

(2013) Kali Janes et al.   PAIN

P2X7 Cell Death Receptor Activation and Mitochondrial Impairment in Oxaliplatin-Induced Apoptosis and Neuronal Injury: Cellular Mechanisms and In Vivo Approach

(2013) France Massicot et al.   PLoS One

A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain

(2013) Cristina Nativi et al.   Scientific Reports

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

(2013) Yaqin Han et al.   Frontiers in Pharmacology

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

(2012) Subir K. Roy Chowdhury et al.   BRAIN

Oxaliplatin-Induced Neuropathy: Oxidative Stress as Pathological Mechanism. Protective Effect of Silibinin

(2012) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF PAIN

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

(2012) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Role of melatonin in the regulation of autophagy and mitophagy: A review

(2012) Ana Coto-Montes et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Chemotherapy-Induced Peripheral Neuropathy: Prevention and Treatment

(2011) D R Pachman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Functional deficits in peripheral nerve mitochondria in rats with paclitaxel- and oxaliplatin-evoked painful peripheral neuropathy

(2011) Huaien Zheng et al.   EXPERIMENTAL NEUROLOGY

Roles of reactive oxygen and nitrogen species in pain

(2011) Daniela Salvemini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

(2011) Amteshwar Singh Jaggi et al.   TOXICOLOGY

Prevention of oxaliplatin-induced mechanical allodynia and neurodegeneration by neurotropin in the rat model

(2010) Takehiro Kawashiri et al.   EUROPEAN JOURNAL OF PAIN

NGF protects Dorsal Root Ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2

(2010) Arianna Scuteri et al.   NEUROSCIENCE LETTERS

Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: Multi-parametric assessment and direct evidence

(2010) Laurence Meyer et al.   PAIN

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

(2009) Zhenyu Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy

(2009) Geeta Negi et al.   NEUROPHARMACOLOGY

Role of MAPKs in platinum-induced neuronal apoptosis

(2009) Arianna Scuteri et al.   NEUROTOXICOLOGY

Chemotherapy-induced peripheral neuropathy: Prevention and treatment strategies

(2008) Sherry Wolf et al.   EUROPEAN JOURNAL OF CANCER