Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders

Caffeine and Coffee as Therapeutics Against Alzheimer's Disease

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson’s Disease

(2016) Ikuko Miyazaki et al.   CURRENT MEDICINAL CHEMISTRY

Glial cells as drug targets: What does it take?

(2016) Thomas Möller et al.   GLIA

Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice

(2016) R. Jiang et al.   JOURNAL OF NEUROSCIENCE

Glia as drivers of abnormal neuronal activity

(2016) Stefanie Robel et al.   NATURE NEUROSCIENCE

Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders

(2016) Alexei Verkhratsky et al.   NEUROBIOLOGY OF DISEASE

Astrocytes in neuroprotection and neurodegeneration: The role of connexin43 and pannexin1

(2016) M. Freitas-Andrade et al.   NEUROSCIENCE

Nrf2–ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

(2016) Izaskun Buendia et al.   PHARMACOLOGY & THERAPEUTICS

“Targeting astrocytes in CNS injury and disease: A translational research approach”

(2016) Angela R. Filous et al.   PROGRESS IN NEUROBIOLOGY

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade

(2016) P. Jourdain et al.   Scientific Reports

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Transcriptome Sequencing of the Anterior Cingulate in Bipolar Disorder: Dysregulation of G Protein-Coupled Receptors

(2015) Cristiana Cruceanu et al.   AMERICAN JOURNAL OF PSYCHIATRY

Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia

(2015) Marco Matos et al.   BIOLOGICAL PSYCHIATRY

High metallothionein predicts poor survival in glioblastoma multiforme

(2015) Ruty Mehrian-Shai et al.   BMC Medical Genomics

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

(2015) D Jimenez-Blasco et al.   CELL DEATH AND DIFFERENTIATION

Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease

(2015) Kou Takahashi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

From Multiple PAR1 Receptor/Protein Interactions to their Multiple Therapeutic Implications

(2015) Marta Gutierrez-Rodriguez et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Neuroprotective agents target molecular mechanisms of disease in ALS

(2015) Yongjin Zhu et al.   DRUG DISCOVERY TODAY

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

(2015) Delinda A. Johnson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hemichannel-mediated release of lactate

(2015) Anastassios Karagiannis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Is L-Lactate a Novel Signaling Molecule in the Brain?

(2015) Valentina Mosienko et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease

(2015) Kou Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular determinants of transport stimulation of EAAT2 are located at interface between the trimerization and substrate transport domains

(2015) Ole V. Mortensen et al.   JOURNAL OF NEUROCHEMISTRY

Current approaches to enhance glutamate transporter function and expression

(2015) Andréia C. K. Fontana   JOURNAL OF NEUROCHEMISTRY

PAR1-Activated Astrocytes in the Nucleus of the Solitary Tract Stimulate Adjacent Neurons via NMDA Receptors

(2015) K. M. Vance et al.   JOURNAL OF NEUROSCIENCE

The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases

(2015) L. Ben Haim et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrogliosis Causes the Development of Spontaneous Seizures

(2015) S. Robel et al.   JOURNAL OF NEUROSCIENCE

Meteorin is upregulated in reactive astrocytes and functions as a negative feedback effector in reactive gliosis

(2015) HYE SHIN LEE et al.   Molecular Medicine Reports

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory

(2015) Anna G Orr et al.   NATURE NEUROSCIENCE

Octadecaneuropeptide ODN prevents hydrogen peroxide-induced oxidative damage of biomolecules in cultured rat astrocytes

(2015) Yosra Hamdi et al.   PEPTIDES

Targeting LDH enzymes with a stiripentol analog to treat epilepsy

(2015) N. Sada et al.   SCIENCE

Filtering the muddied waters of brain edema

(2015) Alexander S. Thrane et al.   TRENDS IN NEUROSCIENCES

Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3

(2015) Martyn A. Sharpe et al.   Oncotarget

Role of Astrocytes in Epilepsy

(2015) D. A. Coulter et al.   Cold Spring Harbor Perspectives in Medicine

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Glia in the pathogenesis of neurodegenerative diseases

(2014) Alexei Verkhratsky et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Involvement of Aquaporin 4 in Astrocyte Function and Neuropsychiatric Disorders

(2014) Ming Xiao et al.   CNS Neuroscience & Therapeutics

Functional regeneration beyond the glial scar

(2014) Jared M. Cregg et al.   EXPERIMENTAL NEUROLOGY

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

(2014) Qiongman Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Ceftriaxone modulates uptake activity of glial glutamate transporter-1 against global brain ischemia in rats

(2014) Yu-Yan Hu et al.   JOURNAL OF NEUROCHEMISTRY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer’s disease

(2014) A. J. Carman et al.   Journal of Nutrition Health & Aging

Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial

(2014) Merit E Cudkowicz et al.   LANCET NEUROLOGY

Post-study caffeine administration enhances memory consolidation in humans

(2014) Daniel Borota et al.   NATURE NEUROSCIENCE

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

(2014) Marie Orre et al.   NEUROBIOLOGY OF AGING

Significance of metallothioneins in aging brain

(2014) Sushil Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1

(2014) Zhihui Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

Optogenetic Countering of Glial Acidosis Suppresses Glial Glutamate Release and Ischemic Brain Damage

(2014) Kaoru Beppu et al.   NEURON

Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system

(2014) Małgorzata Filip et al.   Pharmacological Reports

The effects of the β-lactam antibiotic, ceftriaxone, on forepaw stepping and l-DOPA-induced dyskinesia in a rodent model of Parkinson’s disease

(2014) John E. Kelsey et al.   PSYCHOPHARMACOLOGY

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases

(2014) Hideyuki Takeuchi et al.   Frontiers in Cellular Neuroscience

The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes

(2014) Verónica Abudara et al.   Frontiers in Cellular Neuroscience

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

(2014) Ricardo Cabezas et al.   Frontiers in Cellular Neuroscience

In Vitro and in Vivo Characterization of a Tunable Dual-Reactivity Probe of the Nrf2-ARE Pathway

(2013) Rui Wang et al.   ACS Chemical Biology

The multifaceted role of glial cells in amyotrophic lateral sclerosis

(2013) Chiara F. Valori et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Roles and Therapeutic Potential of Metallothioneins in Neurodegenerative Diseases

(2013) Isao Hozumi   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1

(2013) E. Tokuda et al.   HUMAN MOLECULAR GENETICS

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

(2013) Han-Yun Hsiao et al.   HUMAN MOLECULAR GENETICS

Clinical significance of metallothioneins in cell therapy and nanomedicine

(2013) Sushil Sharma et al.   International Journal of Nanomedicine

Antagonistic Interaction between Adenosine A2A Receptors and Na+/K+-ATPase- 2 Controlling Glutamate Uptake in Astrocytes

(2013) M. Matos et al.   JOURNAL OF NEUROSCIENCE

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Targeting 5-HT1A receptors in astrocytes to protect dopaminergic neurons in parkinsonian models

(2013) Ikuko Miyazaki et al.   NEUROBIOLOGY OF DISEASE

Altered Kir and gap junction channels in temporal lobe epilepsy

(2013) Peter Bedner et al.   NEUROCHEMISTRY INTERNATIONAL

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

SLC1 glutamate transporters

(2013) Christof Grewer et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis

(2013) James D. Berry et al.   PLoS One

Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor

(2013) D. Marazziti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

(2013) Rebecca C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Development of a steady-state FRET-based assay to identify inhibitors of the Keap1-Nrf2 protein-protein interaction

(2013) Marjolein Schaap et al.   PROTEIN SCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3

(2013) Anna M. Wójtowicz et al.   Frontiers in Neural Circuits

Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials

(2013) Paul Gordon et al.   Aging and Disease

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles

(2013) Christian Giaume et al.   Frontiers in Pharmacology

G protein-linked signaling pathways in bipolar and major depressive disorders

(2013) Hiroaki Tomita et al.   Frontiers in Genetics

Expression of mutant N-terminal huntingtin fragment (htt552-100Q) in astrocytes suppresses the secretion of BDNF

(2012) Linhui Wang et al.   BRAIN RESEARCH

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, andIn VitroExperimental Validation

(2012) Tracy P. Williamson et al.   Chemical Biology & Drug Design

Meteorin reverses hypersensitivity in rat models of neuropathic pain

(2012) Jesper Roland Jørgensen et al.   EXPERIMENTAL NEUROLOGY

Deletion of Astroglial Connexins Weakens the Blood–Brain Barrier

(2012) Pascal Ezan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington’s disease

(2012) Benjamin R. Miller et al.   JOURNAL OF NEUROCHEMISTRY

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Astrocyte-Specific Overexpression of Nrf2 Delays Motor Pathology and Synuclein Aggregation throughout the CNS in the Alpha-Synuclein Mutant (A53T) Mouse Model

(2012) L. Gan et al.   JOURNAL OF NEUROSCIENCE

Alexander Disease

(2012) A. Messing et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Targeting proteinase-activated receptors: therapeutic potential and challenges

(2012) Rithwik Ramachandran et al.   NATURE REVIEWS DRUG DISCOVERY

Evidence for astrocytes as a potential source of the glutamate excess in temporal lobe epilepsy

(2012) Edgar L. Perez et al.   NEUROBIOLOGY OF DISEASE

Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus

(2012) Qiongman Kong et al.   NEUROBIOLOGY OF DISEASE

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

The Octadecaneuropeptide ODN Protects Astrocytes against Hydrogen Peroxide-Induced Apoptosis via a PKA/MAPK-Dependent Mechanism

(2012) Yosra Hamdi et al.   PLoS One

Mutation in Parkinson Disease-Associated, G-Protein-Coupled Receptor 37 (GPR37/PaelR) Is Related to Autism Spectrum Disorder

(2012) Eriko Fujita-Jimbo et al.   PLoS One

Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway

(2012) Kai Connie Wu et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Structure–activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators

(2011) Xuechao Xing et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Proteinase-activated receptor-1 mediates dorsal root ganglion neuronal degeneration in HIV/AIDS

(2011) Shaona Acharjee et al.   BRAIN

Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes

(2011) Oleg Palygin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Astrocytes: Implications for Neuroinflammatory Pathogenesis of Alzheimers Disease

(2011) Chuanyu Li et al.   Current Alzheimer Research

Neuron–astrocyte signaling and epilepsy

(2011) Gerald Seifert et al.   EXPERIMENTAL NEUROLOGY

Absence of the GPR37/PAEL receptor impairs striatal Akt and ERK2 phosphorylation, ΔFosB expression, and conditioned place preference to amphetamine and cocaine

(2011) Daniela Marazziti et al.   FASEB JOURNAL

Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10)

(2011) Nadia Nabil Haj-Yasein et al.   GLIA

Reduced Astrocytic Contribution to the Turnover of Glutamate, Glutamine, and GABA Characterizes the Latent Phase in the Kainate Model of Temporal Lobe Epilepsy

(2011) Silje Alvestad et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain Lactate Metabolism: The Discoveries and the Controversies

(2011) Gerald A Dienel   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Protective effect of the octadecaneuropeptide on hydrogen peroxide-induced oxidative stress and cell death in cultured rat astrocytes

(2011) Yosra Hamdi et al.   JOURNAL OF NEUROCHEMISTRY

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

(2011) Juan A. Orellana et al.   JOURNAL OF NEUROCHEMISTRY

Use of viral vectors to create animal models for Parkinson's disease

(2011) Karin Löw et al.   NEUROBIOLOGY OF DISEASE

Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke

(2011) Brandon K. Harvey et al.   PLoS One

Astroglial networks scale synaptic activity and plasticity

(2011) U. Pannasch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet

(2011) N. N. Haj-Yasein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

Immunocytochemical Studies of Aquaporin 4, Kir4.1, and α1-syntrophin in the Astrocyte Endfeet of Mouse Brain Capillaries

(2010) Hisatsugu Masaki et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

(2010) Jeffrey D. Rothstein   ANNALS OF NEUROLOGY

Identification of genes related to heart failure using global gene expression profiling of human failing myocardium

(2010) Kyung-Duk Min et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Therapeutic Role of 5-HT1A Receptors in The Treatment of Schizophrenia and Parkinson's Disease

(2010) Yukihiro Ohno   CNS Neuroscience & Therapeutics

Astrocyte-derived metallothionein protects dopaminergic neurons from dopamine quinone toxicity

(2010) Ikuko Miyazaki et al.   GLIA

Glial and glutamatergic markers in depression, alcoholism, and their comorbidity

(2010) José Javier Miguel-Hidalgo et al.   JOURNAL OF AFFECTIVE DISORDERS

Neuroprotective Drug Riluzole Amplifies the Heat Shock Factor 1 (HSF1)- and Glutamate Transporter 1 (GLT1)-dependent Cytoprotective Mechanisms for Neuronal Survival

(2010) Alice Y. C. Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway

(2010) H. S. Lee et al.   JOURNAL OF CELL SCIENCE

Role of Excitatory Amino Acid Transporter-2 (EAAT2) and glutamate in neurodegeneration: Opportunities for developing novel therapeutics

(2010) Keetae Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease

(2010) Guilian Tian et al.   JOURNAL OF NEUROCHEMISTRY

Alexander Disease Mutant Glial Fibrillary Acidic Protein Compromises Glutamate Transport in Astrocytes

(2010) Rujin Tian et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Implication of Kir4.1 Channel in Excess Potassium Clearance: An In Vivo Study on Anesthetized Glial-Conditional Kir4.1 Knock-Out Mice

(2010) O. Chever et al.   JOURNAL OF NEUROSCIENCE

A mutation in the saposin C domain of the sphingolipid activator protein (Prosaposin) gene causes neurodegenerative disease in mice

(2010) Azusa Yoneshige et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity

(2010) Robert T. R. Huckstepp et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lentiviral delivery of Meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model

(2010) Jesper Roland Jørgensen et al.   NEUROBIOLOGY OF DISEASE

Estimating risk for developing epilepsy: A population-based study in Rochester, Minnesota

(2010) D. C. Hesdorffer et al.   NEUROLOGY

Targeting astrocytes for stroke therapy

(2010) Yanxin Zhao et al.   Neurotherapeutics

Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease

(2010) G. P. Sykiotis et al.   Science Signaling

Role of Astrocytes in Brain Function and Disease

(2010) Marta Sidoryk-Wegrzynowicz et al.   TOXICOLOGIC PATHOLOGY

Astrocyte-Specific Overexpression of Nrf2 Protects Striatal Neurons from Mitochondrial Complex II Inhibition

(2010) Marcus J. Calkins et al.   TOXICOLOGICAL SCIENCES

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Neuroprotective effects of zonisamide target astrocyte

(2009) Masato Asanuma et al.   ANNALS OF NEUROLOGY

Astrocytic dysfunction: Insights on the role in neurodegeneration

(2009) Daniela Rossi et al.   BRAIN RESEARCH BULLETIN

Pharmacological and genetic approaches to study connexin-mediated channels in glial cells of the central nervous system

(2009) Christian Giaume et al.   BRAIN RESEARCH REVIEWS

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function

(2009) Cecily E. Hamill et al.   EXPERIMENTAL NEUROLOGY

The Nrf2–ARE cytoprotective pathway in astrocytes

(2009) Marcelo R. Vargas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

ERK and cell death: ERK1/2 in neuronal death

(2009) Srinivasa Subramaniam et al.   FEBS Journal

Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival

(2009) K. A. Staats et al.   JOURNAL OF BIOLOGICAL PHYSICS

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

(2009) Julien Dusonchet et al.   NEUROBIOLOGY OF DISEASE

Exercise induces metallothioneins in mouse spinal cord

(2009) K. Hashimoto et al.   NEUROSCIENCE

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Relative Importance of Proteinase-Activated Receptor-1 Versus Matrix Metalloproteinases in Intracerebral Hemorrhage-Mediated Neurotoxicity in Mice

(2009) Mengzhou Xue et al.   STROKE

Redox imbalance in Parkinson's disease

(2008) Shankar J. Chinta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

RESEARCH ARTICLE: Up-regulation of Adenosine Receptors in the Frontal Cortex in Alzheimer's Disease

(2008) José L. Albasanz et al.   BRAIN PATHOLOGY

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

(2008) Helga E. de Vries et al.   FREE RADICAL BIOLOGY AND MEDICINE

The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke

(2008) Christa Thöne-Reineke et al.   JOURNAL OF HYPERTENSION

The Good, the Bad, and the Cell Type-Specific Roles of Hypoxia Inducible Factor-1  in Neurons and Astrocytes

(2008) G. Vangeison et al.   JOURNAL OF NEUROSCIENCE

Loss of Astrocytic Domain Organization in the Epileptic Brain

(2008) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Astrocytes in the Epileptic Brain

(2008) Jonathon Wetherington et al.   NEURON

Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

(2008) B.R. Miller et al.   NEUROSCIENCE

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS

(2008) B TURNER et al.   PROGRESS IN NEUROBIOLOGY

Astrocytes and Ischemic Injury

(2008) T. Takano et al.   STROKE