Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1
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Title
Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 23, Issue 5, Pages 1271-1285
Publisher
Oxford University Press (OUP)
Online
2013-10-26
DOI
10.1093/hmg/ddt517
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Note: Only part of the references are listed.- Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities
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