Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

Metalloproteinase-9 contributes to inflammatory glia activation and nigro-striatal pathway degeneration in both mouse and monkey models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism

(2014) V. Annese et al.   Brain Structure & Function

Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons

(2014) C. Proschel et al.   EMBO Molecular Medicine

Disruption of the blood-brain barrier in parkinson's disease: curse or route to a cure?

(2014) Heyne Lee   Frontiers in Bioscience-Landmark

The Role of Pericytes in Neurovascular Unit Remodeling in Brain Disorders

(2014) Ayman ElAli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrogliosis as a therapeutic target for neurodegenerative diseases

(2014) Anna Maria Colangelo et al.   NEUROSCIENCE LETTERS

Análisis comparativo de marcadores de lesión en modelos de isquemia cerebral focal y global en ratas

(2013) Ángel Enrique Céspedes et al.   Biomedica

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glial influence on the blood brain barrier

(2013) Jorge Ivan Alvarez et al.   GLIA

Treatment of Parkinson’s disease in the advanced stage

(2013) C. Ossig et al.   JOURNAL OF NEURAL TRANSMISSION

Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence

(2013) Souhel Najjar et al.   Journal of Neuroinflammation

Pathophysiology of the brain extracellular matrix: a new target for remyelination

(2013) Lorraine W. Lau et al.   NATURE REVIEWS NEUROSCIENCE

Lipopolysaccharide-induced blood brain barrier permeability is enhanced by alpha-synuclein expression

(2013) Adam Jangula et al.   NEUROSCIENCE LETTERS

Ion transporters in brain endothelial cells that contribute to formation of brain interstitial fluid

(2013) Ruth Mokgokong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

Targeted Brain Derived Neurotropic Factors (BDNF) Delivery across the Blood-Brain Barrier for Neuro-Protection Using Magnetic Nano Carriers: An In-Vitro Study

(2013) Sudheesh Pilakka-Kanthikeel et al.   PLoS One

Vascular Endothelial Growth Factor Promotes Pericyte Coverage of Brain Capillaries, Improves Cerebral Blood Flow During Subsequent Focal Cerebral Ischemia, and Preserves the Metabolic Penumbra

(2013) Anil Zechariah et al.   STROKE

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Is There a Causal Link between Inflammation and Dementia?

(2013) Ana-Maria Enciu et al.   Biomed Research International

The blood-brain barrier in health and disease

(2012) Richard Daneman   ANNALS OF NEUROLOGY

Updates in the medical management of Parkinson disease

(2012) H. H. FERNANDEZ   CLEVELAND CLINIC JOURNAL OF MEDICINE

Managing the patient with newly diagnosed Parkinson disease

(2012) C. SINGER   CLEVELAND CLINIC JOURNAL OF MEDICINE

Therapies in Parkinsonʼs disease

(2012) Joseph Jankovic et al.   CURRENT OPINION IN NEUROLOGY

Blood-Brain Barrier P-Glycoprotein Function in Neurodegenerative Disease

(2012) A.L. Bartels   CURRENT PHARMACEUTICAL DESIGN

Brain pericyte plasticity as a potential drug target in CNS repair

(2012) Simona Lange et al.   DRUG DISCOVERY TODAY

Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse

(2012) George E. Barreto et al.   EXPERIMENTAL NEUROLOGY

Defense at the border: the blood–brain barrier versus bacterial foreigners

(2012) Nina M van Sorge et al.   Future Microbiology

Pathophysiology of the Neurovascular Unit: Disease Cause or Consequence?

(2012) Danica B Stanimirovic et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular Unit: a Focus on Pericytes

(2012) Inês Sá-Pereira et al.   MOLECULAR NEUROBIOLOGY

Fibroblast growth factors preserve blood–brain barrier integrity through RhoA inhibition after intracerebral hemorrhage in mice

(2012) Bin Huang et al.   NEUROBIOLOGY OF DISEASE

Neuroprotection from Stroke in the Absence of MHCI or PirB

(2012) Jaimie D. Adelson et al.   NEURON

PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

(2011) Hung-Li Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia

(2011) K. Elisabet Ohlin et al.   BRAIN

Neurotrophic factors for the treatment of Parkinson's disease

(2011) Aideen M. Sullivan et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Topiramate Treatment Protects Blood-Brain Barrier Pericytes from Hyperglycemia-Induced Oxidative Damage in Diabetic Mice

(2011) Tulin O. Price et al.   ENDOCRINOLOGY

Rotenone, Paraquat, and Parkinson’s Disease

(2011) Caroline M. Tanner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases

(2011) Paula Grammas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The role of pericytes in angiogenesis

(2011) Domenico Ribatti et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Future Treatments for Parkinson's Disease: Surfing the PD Pipeline

(2011) Robert A. Hauser   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Optimized Quantities of GDNF Overexpressed by Engineered Astrocytes Are Critical for Protection of Neuroblastoma Cells Against 6-OHDA Toxicity

(2011) Roya Safi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Evidence for angiogenesis in Parkinson’s disease, incidental Lewy body disease, and progressive supranuclear palsy

(2011) Brinda Desai Bradaric et al.   JOURNAL OF NEURAL TRANSMISSION

Signaling Pathways in Reactive Astrocytes, a Genetic Perspective

(2011) Wenfei Kang et al.   MOLECULAR NEUROBIOLOGY

Glia: Initiators and progressors of pathology in Parkinson's disease

(2011) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Evaluation of Markers of Oxidative Stress, Antioxidant Function and Astrocytic Proliferation in the Striatum and Frontal Cortex of Parkinson’s Disease Brains

(2011) Rajeswara Babu Mythri et al.   NEUROCHEMICAL RESEARCH

Astrocytic-neuronal crosstalk: Implications for neuroprotection from brain injury

(2011) George E. Barreto et al.   NEUROSCIENCE RESEARCH

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

(2011) S. T. Papadeas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Brain Injury and Worsened Neurological Outcome in Interleukin-4 Knockout Mice After Transient Focal Cerebral Ischemia

(2011) Xiaoxing Xiong et al.   STROKE

Ca2+ sources for the exocytotic release of glutamate from astrocytes

(2010) Vladimir Parpura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Use of growth factors for the treatment of Parkinson’s disease

(2010) Toru Yasuda et al.   Expert Review of Neurotherapeutics

The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6

(2010) Rituraj Niranjan et al.   FREE RADICAL RESEARCH

Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity

(2010) Diêgo Madureira de Oliveira et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Ascorbic Acid Prevents Blood–Brain Barrier Disruption and Sensory Deficit Caused by Sustained Compression of Primary Somatosensory Cortex

(2010) Jia-Li Lin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Astrocytes and therapeutics for Parkinson’s disease

(2010) Phillip M. Rappold et al.   Neurotherapeutics

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

IGF-1 Can Either Protect Against or Increase LPS-Induced Damage in the Developing Rat Brain

(2010) Yi Pang et al.   PEDIATRIC RESEARCH

Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice

(2010) Francisco Pan-Montojo et al.   PLoS One

Mitophagy: the latest problem for Parkinson's disease

(2010) Cristofol Vives-Bauza et al.   TRENDS IN MOLECULAR MEDICINE

Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

(2010) Xing-Long Gu et al.   Molecular Brain

Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease

(2009) Mark P. Mattson   Annals of the New York Academy of Sciences

Selective Estrogen Receptor Modulators Decrease Reactive Astrogliosis in the Injured Brain: Effects of Aging and Prolonged Depletion of Ovarian Hormones

(2009) George Barreto et al.   ENDOCRINOLOGY

Astrocyte function and role in motor neuron disease: A future therapeutic target?

(2009) Daniel Blackburn et al.   GLIA

Conditional deletion of β1-integrin in astroglia causes partial reactive gliosis

(2009) Stefanie Robel et al.   GLIA

Rho-Associated Kinase II (ROCKII) Limits Axonal Growth after Trauma within the Adult Mouse Spinal Cord

(2009) P. Duffy et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved

(2009) Lianshun Zheng et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Blood-brain barrier alterations in ageing and dementia

(2009) Bogdan O. Popescu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Are growth factors the answer?

(2009) Shilpa Ramaswamy et al.   PARKINSONISM & RELATED DISORDERS

The severity of leukoaraiosis correlates with the clinical phenotype of Parkinson’s disease

(2008) Seung-Jae Lee et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Redox imbalance in Parkinson's disease

(2008) Shankar J. Chinta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Brain endothelial cells and the glio-vascular complex

(2008) Hartwig Wolburg et al.   CELL AND TISSUE RESEARCH

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

(2008) J. Weber et al.   CURRENT MEDICINAL CHEMISTRY

Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier

(2008) Svetlana Stamatovic et al.   Current Neuropharmacology

Pericytes: Pluripotent Cells of the Blood Brain Barrier

(2008) Paula Dore-Duffy   CURRENT PHARMACEUTICAL DESIGN

Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA

(2008) A. L. Bartels et al.   JOURNAL OF NEURAL TRANSMISSION

Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum

(2008) Xuesong Chen et al.   JOURNAL OF NEUROCHEMISTRY

Dissociation of Metabolic and Neurovascular Responses to Levodopa in the Treatment of Parkinson's Disease

(2008) S. Hirano et al.   JOURNAL OF NEUROSCIENCE

Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease

(2008) Jose A. Botella et al.   NEUROBIOLOGY OF DISEASE

Treatment of Parkinson’s disease with trophic factors

(2008) Amie L. Peterson et al.   Neurotherapeutics

Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71

(2008) Gennaro Giordano et al.   NEUROTOXICOLOGY

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY