Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes

(2014) R. F. Deighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Deighton et al.: Neuronal activity regulates distinct antioxidant pathways in neurons and astrocytes

(2014) A. Habas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Neuronal activity regulates astrocytic Nrf2 signaling

(2013) A. Habas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

(2012) P Rodriguez-Rodriguez et al.   CELL DEATH AND DIFFERENTIATION

Synaptic NMDA Receptors Mediate Hypoxic Excitotoxic Death

(2012) C. M. Wroge et al.   JOURNAL OF NEUROSCIENCE

Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes

(2011) Oleg Palygin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

Regulation and role of cyclin-dependent kinase activity in neuronal survival and death

(2010) Shin-ichi Hisanaga et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Characterisation of the Expression of NMDA Receptors in Human Astrocytes

(2010) Ming-Chak Lee et al.   PLoS One

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

(2010) K. F. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway

(2010) R. E. Haskew-Layton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

PKCδ regulates cortical radial migration by stabilizing the Cdk5 activator p35

(2009) Chun-tao Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

(2008) Carolina Maestre et al.   EMBO JOURNAL

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c

(2008) Allyson E. Vaughn et al.   NATURE CELL BIOLOGY

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Transient global ischemia in rat brain promotes different NMDA receptor regulation depending on the brain structure studied

(2008) Severiano Dos-Anjos et al.   NEUROCHEMISTRY INTERNATIONAL

Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes

(2008) Miguel Salazar et al.   TOXICOLOGY